Functional neurology最新文献_第3页

Automated mechanical peripheral stimulation and postural control in subjects with Parkinson's disease and freezing of gait: a randomized controlled trial. 帕金森病和步态冻结受试者的自动机械外周刺激和姿势控制:一项随机对照试验

Functional neurology Pub Date : 2018-10-01

J S Prusch, A F R Kleiner, A P Salazar, C Pinto, R R Marchese, M Galli, A S Pagnussat

引用次数: 0

Is there a correlation between urological and cardiovascular dysfunction in Parkinson's disease? 帕金森病患者的泌尿系统和心血管功能障碍之间是否存在相关性?

Functional neurology Pub Date : 2018-10-01

Livia Brusa, C Rocchi, V Ponzo, Paolo Stanzione, E Finazzi, A Attanasio

引用次数: 0

The dawn of algometry: Paolo Mantegazza's research on pain. 算术的曙光:保罗·曼特加扎对疼痛的研究。

Functional neurology Pub Date : 2018-10-01

V Cani

引用次数: 0

From paper to informatics: the Post Soft Care-App, an easy-to-use and fast tool to help therapists identify unmet needs in stroke patients. 从论文到信息学:Post Soft Care-App，一个易于使用和快速的工具，帮助治疗师识别中风患者未满足的需求。

Functional neurology Pub Date : 2018-10-01

D De Bartolo, G Morone, A Lupo, F Aloise, A Baricich, D Di Francesco, C Calderone, C Cisari, G Verdecchia, Giorgio Sandrini, C Pistarini, G Antonucci, Nicola Smania, Stefano Paolucci, M Iosa

{"title":"From paper to informatics: the Post Soft Care-App, an easy-to-use and fast tool to help therapists identify unmet needs in stroke patients.","authors":"D De Bartolo, G Morone, A Lupo, F Aloise, A Baricich, D Di Francesco, C Calderone, C Cisari, G Verdecchia, Giorgio Sandrini, C Pistarini, G Antonucci, Nicola Smania, Stefano Paolucci, M Iosa","doi":"","DOIUrl":"","url":null,"abstract":"Even after rehabilitation, post stroke patients remain disabled. The Post Stroke Checklist (PSC) was developed to highlight unmet needs of community-dwelling stroke patients. The present study set out to validate Post Soft Care-App, designed to administer the PSC using smartphones and tablets, in order to monitor unmet needs in chronic patients. Fifty-three patients and fifteen physiotherapists were enrolled. The therapists administered the PSC to patients using the app, and then completed a structured questionnaire on its usability and utility. The Post Soft Care-App highlighted the following unmet needs: increased spasticity (56.6%), reduced independence in activities of daily living (47.2%), reduced mobility (45.3%), absence of secondary prevention (45.3%). Therapists positively evaluated Post Soft Care-App as useful, practical, quick to complete (96.2%), and effective in helping improve communication with patients (75.5%). The Post Soft Care-App can be considered a valid assessment tool for helping therapists to monitor functional outcomes in chronic patients.","PeriodicalId":12560,"journal":{"name":"Functional neurology","volume":"33 4","pages":"200-205"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36882522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiple sclerosis and non-dystrophic myotonias: do they share a common pathophysiology? 多发性硬化症和非营养不良性肌强直:它们有共同的病理生理学吗?

Functional neurology Pub Date : 2018-10-01

S Portaro, A Naro, M Russo, P Bramanti, P Lauria, Giangaetano D'Aleo, G La Rosa, A Bramanti, Rocco Salvatore Calabrò

{"title":"Multiple sclerosis and non-dystrophic myotonias: do they share a common pathophysiology?","authors":"S Portaro, A Naro, M Russo, P Bramanti, P Lauria, Giangaetano D'Aleo, G La Rosa, A Bramanti, Rocco Salvatore Calabrò","doi":"","DOIUrl":"","url":null,"abstract":"Some patients with multiple sclerosis (MS) complain of symptoms, such as myokymia, myotonia, spasms, and stiffness, which have been demonstrated to be due to a concurrent non-dystrophic myotonia, i.e. myotonia congenita or paramyotonia congenita. Beyond the known casual association between MS and non-dystrophic myotonia, a channelopathy representing a primary trait of MS rather than an epiphenomenon of demyelization (i.e., an acquired channelopathy) may exist. Indeed, the finding of MS patients with no genetic evidence of non-dystrophic myotonia but showing a clinical picture resembling this condition would support this hypothesis. Thirty patients with MS and no concurrent diagnosis of myotonia congenita or paramyotonia congenita were submitted to the Fournier protocol. Some of these MS patients presented abnormal muscle excitability with scarce myotonic discharges, but only a few of them had clinical features compatible with myotonia congenita or paramyotonia congenita syndromes. Even though the low number of recruited patients did not allow a robust statistical analysis, our data seemed to indicate the presence of an ion channel dysfunction that is independent of the acquired channelopathies and likely represents a common pathophysiological mechanism underlying a unique channelopathy simultaneously involving the peripheral and the central nervous system in individuals with MS. Confirming the presence of such a primary channelopathy in MS patients is of non-negligible importance, since dysfunction of ion channels may represent a suitable therapeutic target in MS.","PeriodicalId":12560,"journal":{"name":"Functional neurology","volume":"33 4","pages":"194-199"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36924905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recovery of circadian melatonin rhythm after a melatonin holiday in daytime haemodialysis patients on long-term exogenous melatonin. 长期服用外源性褪黑素的日间血液透析患者褪黑素假期后褪黑素昼夜节律的恢复。

Functional neurology Pub Date : 2018-10-01

S Sparla, B C Koch, R Bosma, Elsbeth Nagtegaal

{"title":"Recovery of circadian melatonin rhythm after a melatonin holiday in daytime haemodialysis patients on long-term exogenous melatonin.","authors":"S Sparla, B C Koch, R Bosma, Elsbeth Nagtegaal","doi":"","DOIUrl":"","url":null,"abstract":"The effects of exogenous melatonin on sleep diminish after its long-term use in haemodialysis patients. Our aim was to determine whether melatonin levels accumulate after chronic (at least three months) use of exogenous melatonin, 5 mg daily, and whether discontinuation of this treatment improves endogenous melatonin production and improves the circadian sleep-wake rhythm. In this case series, stable haemodialysis patients discontinued their chronic exogenous melatonin usage for seven days and melatonin concentrations in saliva were analysed. The primary endpoint was recovery of a normal circadian melatonin rhythm. Secondary endpoints were the effects on melatonin pharmacokinetics and sleep parameters. At day three after discontinuation the normal circadian melatonin rhythm recovered in the two patients who discontinued the treatment for the full week. They also had an effective maximum trough level of melatonin. Discontinuing melatonin seems to result in recovery of the circadian rhythm, based on achievement of effective melatonin thresholds. Further research is necessary to investigate whether sleep parameters improve after a drug holiday.most appropriate treatment.","PeriodicalId":12560,"journal":{"name":"Functional neurology","volume":"33 4","pages":"188-193"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36924906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

TIA patients with higher ABCD3-I scores are prone to a higher incidence of intracranial stenosis, unstable carotid plaques and multiple-vessel involvement. ABCD3-I评分较高的TIA患者颅内狭窄、不稳定颈动脉斑块和多血管受累的发生率较高。

Functional neurology Pub Date : 2018-10-01

Q Yu, W Miao, J Han

引用次数: 0

Cross-cultural adaptation and validation in the Italian population of the wolf motor function test in patients with stroke. 意大利人群脑卒中患者wolf运动功能测试的跨文化适应和验证。

Functional neurology Pub Date : 2018-10-01

A Berardi, L Dhrami, M Tofani, Donatella Valente, J Sansoni, G Galeoto

{"title":"Cross-cultural adaptation and validation in the Italian population of the wolf motor function test in patients with stroke.","authors":"A Berardi, L Dhrami, M Tofani, Donatella Valente, J Sansoni, G Galeoto","doi":"","DOIUrl":"","url":null,"abstract":"Motor impairments of the upper extremities affect approximately 60% of stroke patients. Rehabilitation is extremely important and can make it possible to identify which manual function is causing difficulty for the patient and hindering daily activities. The Wolf Motor Function Test (WMFT) was recently highly recommended as one of several outcome measures that assess limitations of activities with a high level of psychometrics and clinical utility. The objective of this study was to translate and culturally adapt the WMFT for the Italian population (WMFT-IT) and examine its reliability and validity in Italian post-stroke adults with chronic hemiplegia or hemiparesis. The original scale was translated into Italian and culturally adapted in accordance with international guidelines. Its internal consistency and stability were examined using the Cronbach's alpha (α) coefficient and the intra-class correlation coefficient (ICC), respectively. Its concurrent validity was evaluated using the Pearson's correlation coefficient to compare the instrument with the Italian version of the Jebsen-Taylor Hand Function Test and the Disabilities of the Arm, Shoulder and Hand outcome measure. All WMFT-IT items were either identical or similar in meaning to the items in the original version. The WMFT-IT was administered to 24 subjects. Cronbach's α was 0.91 and 0.98 for the time and performance subscales respectively, and the ICC for test-retest reliability was 0.99. Pearson's correlation coefficients of the time subscale and the performance subscale both showed significant positive correlations (p <0.01). The WMFT-IT was found to be reliable and a valid outcome measure for assessing function and quality of movement of the upper extremities in post-stroke adults in the Italian population.","PeriodicalId":12560,"journal":{"name":"Functional neurology","volume":"33 4","pages":"229-253"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36882523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Automated mechanical peripheral stimulation and postural control in subjects with Parkinson's disease and freezing of gait: a randomized controlled trial. 帕金森病和步态冻结受试者的自动机械外周刺激和姿势控制：一项随机对照试验。

Functional neurology Pub Date : 2018-10-01 DOI: 10.11138/FNEUR/2018.33.4.206

J. S. Prusch, A. Kleiner, A. P. Salazar, C. Pinto, R. Marchese, M. Galli, A. Pagnussat

引用次数: 6

Clinical and neuroimaging spectrum of hyperglycemia-associated chorea-ballism: systematic review and exploratory analysis of case reports. 高血糖相关性舞蹈症的临床和神经影像学：系统回顾和病例报告的探索性分析。

Functional neurology Pub Date : 2018-10-01

Sergio Alejandro Gómez-Ochoa, Blanca Beatriz Espín-Chico, Gabriel David Pinilla-Monsalve, Bonnie M Kaas, Luis Ernesto Téllez-Mosquera

{"title":"Clinical and neuroimaging spectrum of hyperglycemia-associated chorea-ballism: systematic review and exploratory analysis of case reports.","authors":"Sergio Alejandro Gómez-Ochoa, Blanca Beatriz Espín-Chico, Gabriel David Pinilla-Monsalve, Bonnie M Kaas, Luis Ernesto Téllez-Mosquera","doi":"","DOIUrl":"","url":null,"abstract":"Hyperglycemia-associated chorea-ballism (HCB) is an infrequent neurological syndrome occurring predominantly in elderly females and in the setting of non-ketotic hyperglycemia (NKH). A systematic review was conducted in accordance with the PRISMA statement. Studies published between 1980 and 2018 that reported demographic, clinical, laboratory and imaging features from patients with HCB were screened. 136 studies describing 286 patients were included in the analysis. The patients included had a median age of 72 years; those with ketotic hyperglycemia (KH) were older (p<0.001). Women and NKH patients were the most frequently affected (63% and 92%, respectively). The median glucose level at admission was 420 mg/dL (IQR 328-535), and was significantly higher in KH (p=0.009). Moreover, the absence of a clear lesion on imaging studies and the finding of bilateral imaging evidence of lesions were each more frequent in the KH group (p=0.036 and p=0.008, respectively). 48 cases (19.4%) presented with bilateral CT/MRI lesions, having higher values of plasma osmolarity compared with the patients with unilateral lesions (p=0.011). Every patient received hypoglycemic treatment, but only 174 (60.84%) were prescribed neuroleptics. 213 patients (84.86%) showed a total recovery, after a median of 14 days (IQR 3-31). Bilateral chorea-ballism was supported by bilateral imaging evidence of involvement in only 60% of the cases (positive predictive value). Patients not prescribed neuroleptics, with negative lentiform nucleus involvement, and age within the third tertile (≥ 78 years) had an odds ratio of 6.6 (CI 95% 1.18-141.10) for a complete clinical recovery. Significant differences were identified between types of hyperglycemia and regarding the clinical and imaging laterality features. Furthermore, the predictor variables evaluated showed potential utility for assessing the prognosis of HCB patients.","PeriodicalId":12560,"journal":{"name":"Functional neurology","volume":"33 4","pages":"175-187"},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36924904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0