Global health & medicine最新文献_第5页

Retrospective observational analysis of prasugrel dosage afterpercutaneous coronary intervention using the Clinical Deep DataAccumulation System database. 应用临床深度数据积累系统数据库对经皮冠状动脉介入治疗后普拉格雷剂量进行回顾性观察分析。

IF 2.3

Global health & medicine Pub Date : 2026-02-28 DOI: 10.35772/ghm.2026.01003

Yukio Hiroi, Yosuke Shimizu, Yukari Uemura, Iori Kajikawa, Ryohei Matsuo, Masaya Yamamoto, Hisao Hara, Satoshi Kodera, Arihiro Kiyosue, Yoshiko Mizuno, Yoshihiro Miyamoto, Masaharu Nakayama, Tetsuya Matoba, Masanobu Ishii, Kenichi Tsujita, Yasushi Sakata, Tomoyuki Kabutoya, Kazuomi Kario, Yasushi Imai, Hisaki Makimoto, Takahide Kohro, Naoyuki Akashi, Hideo Fujita, Ryozo Nagai, Clidas Research Group

{"title":"Retrospective observational analysis of prasugrel dosage afterpercutaneous coronary intervention using the Clinical Deep DataAccumulation System database.","authors":"Yukio Hiroi, Yosuke Shimizu, Yukari Uemura, Iori Kajikawa, Ryohei Matsuo, Masaya Yamamoto, Hisao Hara, Satoshi Kodera, Arihiro Kiyosue, Yoshiko Mizuno, Yoshihiro Miyamoto, Masaharu Nakayama, Tetsuya Matoba, Masanobu Ishii, Kenichi Tsujita, Yasushi Sakata, Tomoyuki Kabutoya, Kazuomi Kario, Yasushi Imai, Hisaki Makimoto, Takahide Kohro, Naoyuki Akashi, Hideo Fujita, Ryozo Nagai, Clidas Research Group","doi":"10.35772/ghm.2026.01003","DOIUrl":"10.35772/ghm.2026.01003","url":null,"abstract":"Prasugrel reduces the recurrence of atherosclerotic cardiovascular disease and restenosis after percutaneous coronary intervention (PCI). However, its actual dosage in Japan has not been well studied. This study aimed to compare different prasugrel doses after PCI using retrospective data from the Clinical Deep Data Accumulation System (CLIDAS) database. A retrospective observational study was conducted using the CLIDAS-PCI database with a 2-year follow-up after PCI. There were 2,869 and 52 patients in the 3.75- and 2.5 mg groups, respectively. The 2.5 mg group was comprised of significantly more female, older, shorter, and lower-body-weight patients and included more patients with a history of coronary artery bypass grafting, stroke, peripheral arterial disease, or active malignancy than the 3.75 mg group. Concomitant medications included antiplatelets, anticoagulants, and statins. Laboratory data showed substantially lower hemoglobin and platelet counts in the 2.5 mg group. Most patients weighed < 50 kg; however, fewer had an estimated glomerular filtration rate < 30 mL/min/1.73 m². Major adverse cardio- and cerebrovascular events were similar between groups. The 2.5 mg group had more non-fatal strokes and major bleeding associated with antithrombotic therapy. In Japan, prasugrel 2.5 mg should be considered to reduce major bleeding in patients with low body weight, older adults, women, those receiving concomitant antithrombotic therapy, and those with low platelet counts.","PeriodicalId":12556,"journal":{"name":"Global health & medicine","volume":"8 1","pages":"39-52"},"PeriodicalIF":2.3,"publicationDate":"2026-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12932064/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147304581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence and risk factors of tuberculosis among slum dwellers and unhoused individuals in Ho Chi Minh City, Vietnam: Insights from a pilot study. 越南胡志明市贫民窟居民和无家可归者中结核病的患病率和危险因素：一项试点研究的见解。

IF 1.4

Global health & medicine Pub Date : 2025-12-31 DOI: 10.35772/ghm.2025.01112

Khuat Thi Hai Oanh, Nguyen Thuy Linh, Masami Fujita, Lam Ngoc Thuy, Nguyen Hong Phuc, Kieu Thi Mai Huong, Le Tuan Anh, Pham Thi Ngoc Mai, Hitoshi Murakami

{"title":"Prevalence and risk factors of tuberculosis among slum dwellers and unhoused individuals in Ho Chi Minh City, Vietnam: Insights from a pilot study.","authors":"Khuat Thi Hai Oanh, Nguyen Thuy Linh, Masami Fujita, Lam Ngoc Thuy, Nguyen Hong Phuc, Kieu Thi Mai Huong, Le Tuan Anh, Pham Thi Ngoc Mai, Hitoshi Murakami","doi":"10.35772/ghm.2025.01112","DOIUrl":"10.35772/ghm.2025.01112","url":null,"abstract":"Tuberculosis is reported as highly prevalent among slum dwellers and unhoused individuals worldwide. We conducted a study to estimate the prevalence of tuberculosis among slum dwellers and unhoused individuals in Ho Chi Minh City, Vietnam, and identified risk factors. An interview and chest X-ray screening of 367 slum dwellers and 32 unhoused individuals was conducted with sputum GeneXpert for X-ray-positive participants. The prevalence of bacteriologically confirmed tuberculosis was 1,504 per 100,000 population (1,362 among slum dwellers and 3,125 among unhoused individuals), and that of interview and chest X-ray positive status was 4,511 per 100,000 population (4,087 among slum dwellers and 9,375 among unhoused individuals). The above data represent 5.4- and 4.1-fold higher prevalence, respectively, compared to the general adult population of Vietnam based on point estimates. Interview and chest X-ray positive status was significantly associated with being 60 years or older (adjusted odds ratio = 5.039, p = 0.005) and having a monthly income below the median (adjusted odds ratio = 4.305, p = 0.037). The estimated high tuberculosis prevalences among the participants call for the need for systematic screening for tuberculosis disease among these populations.","PeriodicalId":12556,"journal":{"name":"Global health & medicine","volume":"7 6","pages":"444-448"},"PeriodicalIF":1.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12757318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145900053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical treatments for early-stage hepatocellular carcinoma: Resection versus transplantation. 早期肝癌的外科治疗：切除与移植。

IF 1.4

Global health & medicine Pub Date : 2025-12-31 DOI: 10.35772/ghm.2025.01133

Takashi Kokudo, Takamune Yamaguchi, Nermin Halkic, Norihiro Kokudo

引用次数: 0

Erratum: CORRIGENDUM.

IF 1.4

Global health & medicine Pub Date : 2025-12-31 DOI: 10.35772/ghm.2025.E1

引用次数: 0

Survey and analysis of sleep status among community-dwelling elderly diabetics: A cross-sectional study in Shanghai, China. 上海市社区老年糖尿病患者睡眠状况调查与分析

IF 1.4

Global health & medicine Pub Date : 2025-12-31 DOI: 10.35772/ghm.2025.01119

Yan Wan, Xiaomin Qian, Wanli Zhang, Yi Dong, Yuxin Huang, Wen Qin, Jiaojiao Bai, Aili Dong

{"title":"Survey and analysis of sleep status among community-dwelling elderly diabetics: A cross-sectional study in Shanghai, China.","authors":"Yan Wan, Xiaomin Qian, Wanli Zhang, Yi Dong, Yuxin Huang, Wen Qin, Jiaojiao Bai, Aili Dong","doi":"10.35772/ghm.2025.01119","DOIUrl":"10.35772/ghm.2025.01119","url":null,"abstract":"Sleep is crucial to maintaining physiological stability and exhibits a bidirectional relationship with metabolic health. This study used random sampling to investigate sleep status and factors influencing it among 585 community-dwelling elderly diabetics (age ≥ 60 years) in Shanghai (April-August 2025). Data were collected through a self-designed general questionnaire, the Athens Insomnia Scale (AIS), and clinical biochemical tests. Univariate analysis and binary logistic regression were used to identify influencing factors. Results indicated a median AIS score of 4.0 (3.0, 6.0), with 26.84% of patients (157/585) experiencing sleep problems. Univariate analysis revealed significant correlations between sleep quality and sex, level of education, glycated hemoglobin (HbA1c), fasting blood glucose (FBG), urine leukocytes, urine specific gravity, hypertension, the number of comorbidities, and diabetic peripheral neuropathy (p < 0.05 for all). Binary logistic regression analysis identified that being female (OR = 1.778, 95% CI: 1.115-2.836, p = 0.016), having a college degree or above (OR = 2.820, 95% CI: 1.305-6.092, p = 0.008), elevated glycated hemoglobin (OR = 1.460, 95% CI: 1.221-1.745, p < 0.001), elevated fasting blood glucose (OR = 1.490, 95% CI: 1.327-1.673, p < 0.001), and diabetic peripheral neuropathy (OR = 1.713, 95% CI: 1.046-2.804, p = 0.032) were independent risk factors for sleep disorders. Implementing individualized, multidimensional management for these high-risk populations is crucial to enhancing the overall effectiveness of diabetes prevention and control.","PeriodicalId":12556,"journal":{"name":"Global health & medicine","volume":"7 6","pages":"432-438"},"PeriodicalIF":1.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12757319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145900117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of healthy lifestyles on cognitive function in community-dwelling older adults: A cross-sectional study in Shanghai, China. 健康生活方式对社区老年人认知功能的影响：一项来自中国上海的横断面研究

IF 1.4

Global health & medicine Pub Date : 2025-12-31 DOI: 10.35772/ghm.2025.01092

Guyanan Li, Lihua Zhu, Xinyu Li, Biying Wu, Jianyu Chen

{"title":"The impact of healthy lifestyles on cognitive function in community-dwelling older adults: A cross-sectional study in Shanghai, China.","authors":"Guyanan Li, Lihua Zhu, Xinyu Li, Biying Wu, Jianyu Chen","doi":"10.35772/ghm.2025.01092","DOIUrl":"10.35772/ghm.2025.01092","url":null,"abstract":"Recent literature has demonstrated the link between lifestyle behavior factors and cognitive function, yet most evidence comes from Western populations. This study examined the associations between multiple healthy lifestyle factors and cognitive function among community-dwelling older adults in Shanghai, China. This cross-sectional study included 942 residents aged ≥ 60 years in Pudong District, Shanghai, China, who participated in China's national free physical examination program from July to September 2024. Cognitive function and cognitive impairment status were assessed by Mini-Mental State Examination (MMSE). Five healthy lifestyle factors were considered: never smoking, healthy body mass index, regular physical activity, light-to-moderate alcohol drinking and optimal night sleep duration. A composite healthy lifestyle score (0-5) was calculated. Results showed that regular physical activity and optimal night sleep duration were positively correlated with a MMSE score [β = 0.21 (95% confidence interval (CI): 0.09-0.34), p = 0.001; β = 0.15 (95% CI: 0.03-0.27), p = 0.016, respectively], and were significantly associated with lower odds of cognitive impairment [odds ratio (OR) = 0.69 (95% CI: 0.47-0.98); OR = 0.66 (95% CI: 0.45-0.95), respectively]. Compared with participants with ≤ 1 healthy lifestyle factor, the β (95% CI) of MMSE score for participants with 3, and 4-5 healthy lifestyle factors were 0.26 (0.08-0.44) and 0.25 (0.04-0.47), respectively; and the OR and 95% CI for participants with 3 healthy lifestyle factors were 0.59 (0.34-0.98). Adherence to multiple healthy lifestyle behaviors, particularly regular physical activity and adequate night sleep, was associated with better cognitive function among elders in Shanghai.","PeriodicalId":12556,"journal":{"name":"Global health & medicine","volume":"7 6","pages":"423-431"},"PeriodicalIF":1.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12757316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145900065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Responding to a super-aged society: A community-based model for early frailty detection using AI and smart meter data -Insights from Japan. 应对超老龄化社会：利用人工智能和智能电表数据进行早期虚弱检测的社区模型——来自日本的见解。

IF 1.4

Global health & medicine Pub Date : 2025-12-31 DOI: 10.35772/ghm.2025.01114

Machiko Uenishi, Peipei Song

{"title":"Responding to a super-aged society: A community-based model for early frailty detection using AI and smart meter data -Insights from Japan.","authors":"Machiko Uenishi, Peipei Song","doi":"10.35772/ghm.2025.01114","DOIUrl":"10.35772/ghm.2025.01114","url":null,"abstract":"Japan, at the forefront of a super-aged society where individuals age 65 and older constitute 29.3% of the total population, faces an urgent need for early detection of and intervention in reversible geriatric syndromes known as frailty to prevent older adults from becoming dependent on long-term care. One notable innovation is the frailty detection service e-Frail Navi, which began operational in 2023 following pilot testing since 2020. This service analyzes household electricity consumption patterns using AI, sending alerts to municipal welfare departments when unusual behavioral patterns are detected, enabling early intervention through professional home visits. A groundbreaking community-based integrated care model leveraging digital technology, 29 municipalities have adopted it as of June 2025. However, several challenges remain regarding the use of such technology, including issues with the accuracy of frailty assessment, ethical and legal concerns, and the potential barriers to use posed by disparities in digital literacy and economic circumstances.","PeriodicalId":12556,"journal":{"name":"Global health & medicine","volume":"7 6","pages":"439-443"},"PeriodicalIF":1.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12757314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145900055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Breast cancer screening challenges in women with breast augmentation: Evidence from a comprehensive health checkup program. 隆胸妇女的乳腺癌筛查挑战：来自全面健康检查计划的证据。

IF 1.4

Global health & medicine Pub Date : 2025-12-31 DOI: 10.35772/ghm.2025.01110

Jun Lu, Sachiko Kubo, Makiko Hashimoto, Yuko Hayashi, Erika Masuda, Yukio Hiroi

{"title":"Breast cancer screening challenges in women with breast augmentation: Evidence from a comprehensive health checkup program.","authors":"Jun Lu, Sachiko Kubo, Makiko Hashimoto, Yuko Hayashi, Erika Masuda, Yukio Hiroi","doi":"10.35772/ghm.2025.01110","DOIUrl":"10.35772/ghm.2025.01110","url":null,"abstract":"Breast augmentation may compromise the accuracy of breast cancer screening and mammography in particular. The aim of this study was to assess its impact on screening practices and the need for diagnostic follow-up. Data from 1,596 women undergoing comprehensive health checkups in 2024 were retrospectively analyzed. Among 912 women screened for breast cancer, 853 underwent both a mammography and ultrasound, while 54 underwent ultrasound only. Additional evaluation was required in 41/853 (4.8%) of the combined screening group compared to 1/54 (1.9%) of the ultrasound-only group. Breast augmentation was identified in 13/912 (1.43%) using extended detection, and 13/912 (1.43%) in the dedicated field. These findings highlight the limitations of mammography in augmented breasts. Breast augmentation influences screening choices and may hinder cancer detection. Alternative modalities, such as diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) MRI or low-compression 3D mammography, should be considered to improve detection accuracy and patient outcomes.","PeriodicalId":12556,"journal":{"name":"Global health & medicine","volume":"7 6","pages":"454-456"},"PeriodicalIF":1.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12757311/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145900144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Converging threats: The intersection of seasonal influenza surges and zoonotic highly pathogenic avian influenza. 趋同的威胁：季节性流感激增和人畜共患高致病性禽流感的交叉。

IF 1.4

Global health & medicine Pub Date : 2025-12-31 DOI: 10.35772/ghm.2025.01136

Wei Yang, Haiyun Xiong, Rui Zhao, Yang Yang, Hongzhou Lu

{"title":"Converging threats: The intersection of seasonal influenza surges and zoonotic highly pathogenic avian influenza.","authors":"Wei Yang, Haiyun Xiong, Rui Zhao, Yang Yang, Hongzhou Lu","doi":"10.35772/ghm.2025.01136","DOIUrl":"10.35772/ghm.2025.01136","url":null,"abstract":"The global landscape of influenza is becoming increasingly complex. In the Northern Hemisphere, seasonal influenza activity is exhibiting a pattern of \"early onset, high intensity\". At the same time, highly pathogenic avian influenza (HPAI) continues to circulate widely among wild birds and poultry, with a growing tendency to spillover into mammals, including dairy cattle, thereby substantially increasing the zoonotic risk. This convergence exposes the limitations of control systems that manage human and animal influenza separately. Given the ongoing cross-species adaptive evolution of influenza viruses at the human-animal-environment interface, global strategies need to pivot toward a fully integrated One Health paradigm as the organizing principle for preparedness and response. By synthesizing surveillance data and research capacity across human, animal, and environmental health sectors, the international community can build a more resilient defense network that both reduces the current disease burden and helps pre-empt the emergence of novel pandemic strains arising from viral reassortment.","PeriodicalId":12556,"journal":{"name":"Global health & medicine","volume":"7 6","pages":"409-413"},"PeriodicalIF":1.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12757313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145900088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improved prognostic predictability of the latest Japanese TNM Classification in patients undergoing resection for distal cholangiocarcinoma. 最新日本TNM分级对远端胆管癌切除患者预后的可预测性提高。

IF 1.4

Global health & medicine Pub Date : 2025-12-31 DOI: 10.35772/ghm.2025.01106

Kohei Nishio, Sayaka Tanaka, Ryota Tanaka, Shigeaki Kurihara, Sadaaki Nishimura, Jun Tauchi, Masahiko Kinoshita, Hiroji Shinkawa, Kenjiro Kimura, Takeaki Ishizawa

{"title":"Improved prognostic predictability of the latest Japanese TNM Classification in patients undergoing resection for distal cholangiocarcinoma.","authors":"Kohei Nishio, Sayaka Tanaka, Ryota Tanaka, Shigeaki Kurihara, Sadaaki Nishimura, Jun Tauchi, Masahiko Kinoshita, Hiroji Shinkawa, Kenjiro Kimura, Takeaki Ishizawa","doi":"10.35772/ghm.2025.01106","DOIUrl":"10.35772/ghm.2025.01106","url":null,"abstract":"In March 2021, the Japanese TNM Classification for Cancer of the Biliary Tract (JCCB) was revised. This study aimed to validate the 7th edition of JCCB based on long-term outcomes after resection for distal cholangiocarcinoma (DCC). We retrospectively reviewed 107 patients with resected DCC without distant metastasis between 2007 and 2019. Survival curves according to TNM factors were compared between the 6th and 7th editions. The 5-year overall survival (OS) and recurrence-free survival rate (RFS) were 43.4% and 35.5%, respectively. Significant differences in OS were observed between T categories in the 7th edition (T1 vs. T2, p = 0.049; T2 vs. T3, p = 0.027), but not in the 6th. The N classification also showed better prognostic discrimination in both editions, with more refined stratification in the 7th. Stage grouping in the 6th edition failed to show significant OS differences, while the 7th edition demonstrated clear stratification (e.g., Stage I vs. IIA, p = 0.0274; StageⅡA vs. StageⅡB, p = 0.0043; StageⅡB vs. StageⅢA, p = 0.0108). These findings indicate that the revised T and N classifications in the 7th edition more accurately reflect postoperative prognosis for resected DCC. Overall, our results support the clinical validity and improved prognostic utility of the 7th edition compared with the 6th edition.","PeriodicalId":12556,"journal":{"name":"Global health & medicine","volume":"7 6","pages":"416-422"},"PeriodicalIF":1.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12757320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145900126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0