Roberto de Sire, Ludovico Alfarone, Antonio Capogreco, Davide Massimi, Vincenzo Vadalà, Luca Brandaleone, Marco Spadaccini, Asma Alkandari, Pradeep Bhandari, Thomas Rosch, Cesare Hassan, Roberta Maselli, Alessandro Repici
{"title":"A Novel Thin-Needle Knife with High-Pressure Waterjet for Colorectal Underwater Endoscopic Submucosal Dissection.","authors":"Roberto de Sire, Ludovico Alfarone, Antonio Capogreco, Davide Massimi, Vincenzo Vadalà, Luca Brandaleone, Marco Spadaccini, Asma Alkandari, Pradeep Bhandari, Thomas Rosch, Cesare Hassan, Roberta Maselli, Alessandro Repici","doi":"10.1016/j.gie.2025.09.043","DOIUrl":"https://doi.org/10.1016/j.gie.2025.09.043","url":null,"abstract":"<p><strong>Background and aims: </strong>A novel thin-needle knife with high-pressure waterjet was developed to enhance endoscopic submucosal dissection (ESD) in terms of ease, speed, and safety. We present first clinical results using this new device.</p><p><strong>Methods: </strong>We included consecutive colorectal underwater ESD cases over 27 months at two therapeutic endoscopy centers. The new knife (HYBRIDknife® flex I-Type, 1.5 mm) was used at the examiner's discretion and compared to various conventional low-pressure waterjet knives. All cases treated with the new knife were matched 1:1 with controls using propensity score analysis based on lesion size, location, morphology, vascular pattern, and operator experience.</p><p><strong>Results: </strong>Forty matched pairs were analyzed. The mean long axis of ex vivo specimen was 47.2 mm (SD 18.8). Dissection speed was significantly higher with the high-pressure knife (36.7 mm<sup>2</sup>/min vs 28.2; p<0.0001), while R0 resection rates were comparable (97.5% vs 95%; p=0.8). The benefit appeared more pronounced among less experienced operators and with technically challenging lesions. Three intraprocedural perforations occurred in the control group only, while one case of post-endoscopic coagulation syndrome was observed in each group.</p><p><strong>Conclusion: </strong>The high-pressure thin-needle knife appears to improve dissection speed with a favorable efficacy and safety profile.</p>","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145181966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jun-Young Seo, Chan-Sik Ahn, Hui-Jeong Kim, Chang-Il Kwon
{"title":"Target biopsy via slim dilating catheter for hilar cholangiocarcinoma.","authors":"Jun-Young Seo, Chan-Sik Ahn, Hui-Jeong Kim, Chang-Il Kwon","doi":"10.1016/j.gie.2025.09.038","DOIUrl":"https://doi.org/10.1016/j.gie.2025.09.038","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145174587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endoscopic Removal of a Large Esophageal Leiomyoma via Bilateral Longitudinal-Transverse Tunneling After Failed Initial Resection.","authors":"Ningning You, Yandi Lu, Yi Chen, Jinshun Zhang","doi":"10.1016/j.gie.2025.09.039","DOIUrl":"https://doi.org/10.1016/j.gie.2025.09.039","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145174655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endoscopic septotomy for Zenker’s diverticulum: Open for discussion?","authors":"Dennis Yang MD","doi":"10.1016/j.gie.2025.03.643","DOIUrl":"10.1016/j.gie.2025.03.643","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":"102 4","pages":"Pages 557-558"},"PeriodicalIF":7.5,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145109943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Interpreting comparative effectiveness of endoscopic mucosal resection versus surgery: the challenge of selection bias","authors":"Xiaoming Xu MD","doi":"10.1016/j.gie.2025.05.008","DOIUrl":"10.1016/j.gie.2025.05.008","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":"102 4","pages":"Pages 623-624"},"PeriodicalIF":7.5,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145109991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Predicting incomplete endoscopic resection of ampullary adenomas: Are you keeping score?","authors":"Jorge V. Obando MD","doi":"10.1016/j.gie.2025.05.004","DOIUrl":"10.1016/j.gie.2025.05.004","url":null,"abstract":"","PeriodicalId":12542,"journal":{"name":"Gastrointestinal endoscopy","volume":"102 4","pages":"Pages 607-608"},"PeriodicalIF":7.5,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145109931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}