{"title":"[Artificial intelligence in cardiology and beyond].","authors":"Roberto Ferrari, Luigi Tavazzi","doi":"10.1714/4488.44884","DOIUrl":"https://doi.org/10.1714/4488.44884","url":null,"abstract":"","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 5","pages":"309-315"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cristina Chimenti, Attilio Iacovoni, Andrea Montalto, Michele Emdin, Iacopo Olivotto, Cristina Basso, Benedetta Carla De Chiara, Irene Bottillo, Claudio Mario Ciampi, Santo Dellegrottaglie, Massimo Di Marco, Piero Gentile, Francesca Girolami, Paola Grammatico, Maria Iascone, Eluisa La Franca, Carla Lofiego, Andrea Matteucci, Daniele Pasqualucci, Samuele Pentiricci, Enrica Perugini, Maurizio Pieroni, Giovanni Quarta, Federica Re, Laura Scelsi, Giancarlo Todiere, Maria Alfarano, Monica De Gaspari, Claudio Bilato, Marco Corda, Leonardo De Luca, Giovanna Geraci, Massimo Milli, Alessandro Navazio, Vittorio Pascale, Carmine Riccio, Pietro Scicchitano, Emanuele Tizzani, Michele Massimo Gulizia, Federico Nardi, Domenico Gabrielli, Furio Colivicchi, Massimo Grimaldi, Fabrizio Oliva
{"title":"[ANMCO Position paper: Hypertrophic cardiomyopathy: from diagnosis to treatment].","authors":"Cristina Chimenti, Attilio Iacovoni, Andrea Montalto, Michele Emdin, Iacopo Olivotto, Cristina Basso, Benedetta Carla De Chiara, Irene Bottillo, Claudio Mario Ciampi, Santo Dellegrottaglie, Massimo Di Marco, Piero Gentile, Francesca Girolami, Paola Grammatico, Maria Iascone, Eluisa La Franca, Carla Lofiego, Andrea Matteucci, Daniele Pasqualucci, Samuele Pentiricci, Enrica Perugini, Maurizio Pieroni, Giovanni Quarta, Federica Re, Laura Scelsi, Giancarlo Todiere, Maria Alfarano, Monica De Gaspari, Claudio Bilato, Marco Corda, Leonardo De Luca, Giovanna Geraci, Massimo Milli, Alessandro Navazio, Vittorio Pascale, Carmine Riccio, Pietro Scicchitano, Emanuele Tizzani, Michele Massimo Gulizia, Federico Nardi, Domenico Gabrielli, Furio Colivicchi, Massimo Grimaldi, Fabrizio Oliva","doi":"10.1714/4488.44889","DOIUrl":"https://doi.org/10.1714/4488.44889","url":null,"abstract":"<p><p>Hypertrophic cardiomyopathy (HCM) is a non-rare genetic cardiomyopathy, with an estimated prevalence of 1:500, characterized by an increase in the left ventricular wall thickness in absence of increased loading conditions. The hypertrophy is mostly asymmetric and predominantly affects the basal septum and anterior wall. Left ventricular outflow tract obstruction, at rest or after provocative tests, is detected in many patients and represents the primary cause of reduced functional capacity, as well as an independent predictor of sudden cardiac death and advanced heart failure. Until about 1 year ago, symptomatic patients despite maximal therapy with beta-blockers or calcium channel blockers, with or without disopyramide, had only basal septal reduction therapy via myectomy or alcohol septal ablation as additional therapeutic options. Today, a new class of drugs that inhibit cardiac myosin activity is available for patients with obstructive HCM.In light of the new treatment perspectives, the correct clinical-therapeutic classification of affected patients becomes of fundamental importance for the cardiologist. The aim of this position paper is to increase the knowledge of cardiologists in the field of HCM, defining its epidemiological, genetic and pathological characteristics, identifying the diagnostic criteria and instrumental methods capable of stratifying the risk profile, with the aim of an optimal therapy tailored on the single patient.</p>","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 5","pages":"356-377"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143994531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lorenzo Bianchi, Sebastiano Stratoti, Giovanni Gnecco
{"title":"[When voltages decrease, the electrical axis can make the difference].","authors":"Lorenzo Bianchi, Sebastiano Stratoti, Giovanni Gnecco","doi":"10.1714/4488.44882","DOIUrl":"https://doi.org/10.1714/4488.44882","url":null,"abstract":"","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 5","pages":"302"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Coronary computed tomography in the clinical arena. Recent evidence and future perspectives].","authors":"Giancarlo Casolo, Jacopo Del Meglio, Carlo Tessa","doi":"10.1714/4488.44887","DOIUrl":"https://doi.org/10.1714/4488.44887","url":null,"abstract":"<p><p>In the past few years, computed tomography coronary angiography (CTCA) has rapidly become a widely used diagnostic tool in several clinical settings and is recommended by the European guidelines with a high degree of recommendation in patients with suspected coronary artery disease. The rapid accumulation of evidence is tumultuous and clinical use has grown in parallel with the possibility of offering significant advantages in many areas. Today, CTCA is used both in the diagnosis of low-risk chest pain in emergency departments and in the recognition and prognostic assessment of stable coronary artery disease. By identifying the presence, extent, and quality of atherosclerotic disease, CTCA today offers an important tool for the identification of the disease, promoting the best therapeutic choices with significant prognostic implications, a high safety profile and potentially significant savings in resources. New applications and evidence are accumulating thanks to the marriage of CTCA with artificial intelligence. Alongside increasing accuracy, new risk markers have been identified that enrich the informative content of this method. This review reports the most significant studies that have marked this path so far.</p>","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 5","pages":"333-346"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144011978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Federico Fortuni, Giuseppe Ciliberti, Mauro Gori, Pietro Scicchitano, Michele Magnesa, Antonella Spinelli, Enrica Vitale, Concetta Di Nora, Luca Franchin, Stefano Cornara, Paolo Manca, Stefano Cangemi, Samuela Carigi, Furio Colivicchi, Massimo Grimaldi, Fabrizio Oliva
{"title":"[Diagnosis and treatment of iron deficiency in heart failure].","authors":"Federico Fortuni, Giuseppe Ciliberti, Mauro Gori, Pietro Scicchitano, Michele Magnesa, Antonella Spinelli, Enrica Vitale, Concetta Di Nora, Luca Franchin, Stefano Cornara, Paolo Manca, Stefano Cangemi, Samuela Carigi, Furio Colivicchi, Massimo Grimaldi, Fabrizio Oliva","doi":"10.1714/4488.44886","DOIUrl":"https://doi.org/10.1714/4488.44886","url":null,"abstract":"<p><p>Patients with heart failure (HF) frequently experience iron deficiency, with an estimated prevalence of sideropenia around 50%. In HF patients, iron deficiency is associated with reduced functional capacity, lower quality of life, and an increased risk of hospitalizations and mortality. Therefore, timely diagnosis and treatment of sideropenia are essential to improve clinical outcomes in HF patients with reduced or mildly reduced ejection fraction, while data on the benefits of iron supplementation in HF patients with preserved ejection fraction remain limited. This review aims to provide an overview of the prevalence, diagnostic criteria, available evidence, indications, iron formulations, and recommended protocols for identifying and treating iron deficiency in HF patients.</p>","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 5","pages":"322-332"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143994533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In questo numero.","authors":"","doi":"10.1714/4488.44880","DOIUrl":"https://doi.org/10.1714/4488.44880","url":null,"abstract":"","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 5","pages":"0"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pier Luigi Temporelli, Andrea Di Lenarda, Riccardo Candido
{"title":"[Oral semaglutide: why we can no longer do without it?]","authors":"Pier Luigi Temporelli, Andrea Di Lenarda, Riccardo Candido","doi":"10.1714/4488.44883","DOIUrl":"https://doi.org/10.1714/4488.44883","url":null,"abstract":"","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 5","pages":"303-308"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144062321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marco Zuin, Daniela Pavan, Giuseppina Maura Francese, Arjuna Scagnetto, Cinzia Radesich, Katya Ranzato, Serafina Valente, Gian Franco Gensini, Andrea Di Lenarda
{"title":"[Artificial intelligence in cardiology: definition, types, glossary, algorithms used - opportunities, limitations, development barriers, and challenges].","authors":"Marco Zuin, Daniela Pavan, Giuseppina Maura Francese, Arjuna Scagnetto, Cinzia Radesich, Katya Ranzato, Serafina Valente, Gian Franco Gensini, Andrea Di Lenarda","doi":"10.1714/4488.44885","DOIUrl":"https://doi.org/10.1714/4488.44885","url":null,"abstract":"<p><p>Artificial intelligence (AI) is revolutionizing cardiology, offering new opportunities to improve diagnosis, therapy, and prevention of cardiovascular diseases. By analyzing large amounts of data and supporting clinical decisions, AI can simplify modern medical complexities. However, its development is limited by methodological, ethical, and organizational obstacles. This review aims to present the potential applications of AI in cardiology in a practical and accessible manner, exploring key algorithms, opportunities, and limitations. It is crucial to address the challenges associated with AI to ensure its ethical and responsible use in support of clinical expertise while actively promoting collaboration between clinicians and information technology specialists to fully realize the potential of AI in daily cardiological practice.</p>","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 5","pages":"316-321"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cristina Chimenti, Aldostefano Porcari, Marco Cittar, Alberto Aimo, Francesco Musca, Alberto Cipriani, Marco Zuin, Simone Longhi, Andrea Di Lenarda, Marco Merlo, Massimo Iacoviello, Marco Canepa, Giuseppe Limongelli, Michele Emdin, Furio Colivicchi, Pasquale Perrone Filardi, Fabrizio Oliva, Gianfranco Sinagra
{"title":"[Management of cardiac amyloidosis in Italy: a national survey of the Italian Cardiac Amyloidosis Network (RIAC)].","authors":"Cristina Chimenti, Aldostefano Porcari, Marco Cittar, Alberto Aimo, Francesco Musca, Alberto Cipriani, Marco Zuin, Simone Longhi, Andrea Di Lenarda, Marco Merlo, Massimo Iacoviello, Marco Canepa, Giuseppe Limongelli, Michele Emdin, Furio Colivicchi, Pasquale Perrone Filardi, Fabrizio Oliva, Gianfranco Sinagra","doi":"10.1714/4488.44888","DOIUrl":"10.1714/4488.44888","url":null,"abstract":"<p><strong>Background: </strong>The national survey of the SIC-ANMCO Amyloidosis Centers was designed to create a geographical mapping of the centers that identify and follow patients with cardiac amyloidosis in Italy and to describe their diagnostic capabilities and multidisciplinary organization.</p><p><strong>Methods: </strong>The survey was administered to 212 centers in Italy. Among them, 153 centers responded (72%), 31/35 (89%) of which were academic medical centers and 122/177 (69%) hospitals.</p><p><strong>Results: </strong>The results revealed a prevalence of centers in the North and Center of Italy compared to the South and the Islands, highlighting a greater number of patients in heart failure/cardiomyopathy clinics in hospitals (53%) and in clinics dedicated to amyloidosis in academic medical centers (71%). Most centers have an internal multidisciplinary collaboration network with the neurologist (82% in total, 97% in academic medical centers and 78% in hospitals) and the hematologist (69% in total, in 94% and 63%, respectively) and have the possibility of performing on-site cardiac magnetic resonance imaging (74%, in 94% and 68%, respectively) and scintigraphy with bone tracers (52%, in 91% and 44%, respectively), or alternatively to refer patients to other centers thanks to well-structured or occasional collaborations. Conversely, only a minority of centers perform endomyocardial biopsy (31%, in 71% of academic medical centers and in 20% of hospitals) and a smaller number of academic medical centers perform sophisticated amyloid tissue typing techniques such as immunogold labeling (11%) and mass spectrometry (4%).</p><p><strong>Conclusions: </strong>The survey provided important information on the current Italian situation, underlining the importance of collaboration between the various levels of the network, to guarantee the best possible pathways and treatments for all patients with amyloidosis.</p>","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 5","pages":"347-355"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Lalario, Enrico Fabris, Serena Rakar, Laura Massa, Alberto Benussi, Gianfranco Sinagra
{"title":"[Cerebral amyloid angiopathy and left atrial appendage occlusion: evidence and possible management for a collaborative approach between Cardiology and Neurology].","authors":"Andrea Lalario, Enrico Fabris, Serena Rakar, Laura Massa, Alberto Benussi, Gianfranco Sinagra","doi":"10.1714/4464.44614","DOIUrl":"10.1714/4464.44614","url":null,"abstract":"<p><p>This review highlights the epidemiological and clinical challenge associated with managing patients who have cerebral amyloid angiopathy (CAA) and atrial fibrillation. As the population ages, clinicians are increasingly required to devise appropriate management strategies for this specific patient subgroup. These patients face not only the risk of intracerebral hemorrhage associated with oral anticoagulant therapy but also complications due to CAA. CAA is an age-related small vessel disease characterized by the deposition of β-amyloid in the walls of cortical and leptomeningeal arteries, arterioles, and capillaries. This condition progressively weakens the vascular integrity, thereby increasing the risk of major bleeding events. The lack of randomized clinical trials necessitates a multiparametric and multidisciplinary approach to assess the extent of vasculopathy and balance thromboembolic and hemorrhagic risks, aiming to tailor the most effective management strategy for each patient. In managing such cases, it is crucial to address concomitant risk factors and consider both pharmacological and non-pharmacological interventions, such as left atrial appendage occlusion, to mitigate the risk of stroke.</p>","PeriodicalId":12510,"journal":{"name":"Giornale italiano di cardiologia","volume":"26 4","pages":"251-260"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}