Frontiers in Microbiology最新文献

{"title":"Internal in-frame translation generates Cas11b, which is important for effective interference in an archaeal CRISPR-Cas system.","authors":"A-L Sailer, J Brendel, A Chernev, S König, T Bischler, T Gräfenhan, H Urlaub, U Gophna, A Marchfelder","doi":"10.3389/fmicb.2025.1543464","DOIUrl":"10.3389/fmicb.2025.1543464","url":null,"abstract":"<p><p>CRISPR-Cas is a sophisticated defence system used by bacteria and archaea to fend off invaders. CRISPR-Cas systems vary in their Cas protein composition and have therefore been divided into different classes and types. Type I systems of bacteria have been shown to contain the small protein Cas11 as part of the interference complex known as Cascade. Here we show for the first time that an archaeal CRISPR-Cas type I-B system also contains a homolog of Cas11. The Cas11b protein, encoded by the <i>cas8b</i> gene in <i>Haloferax volcanii</i>, represents the first known case of an internal in-frame translation of an archaeal protein. Translation initiation at an internal methionine of the <i>cas8b</i> open reading frame results in synthesis of Cas11b. Cas11b is required for an effective CRISPR-Cas interference reaction, and in its absence fewer Cascade complexes are formed. Comparison of transcriptomes from wild type and a Cas11b-less strain shows that the depletion of Cas11b also results in differential transcript abundance of many genes, presumably affecting their regulation. Taken together, Cas11b is important for the defence reaction of the type I-B CRISPR-Cas system and seems to play an additional cellular role.</p>","PeriodicalId":12466,"journal":{"name":"Frontiers in Microbiology","volume":"16 ","pages":"1543464"},"PeriodicalIF":4.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11899642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143614147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spatial and temporal groundwater biogeochemical variability help inform subsurface connectivity within a high-altitude Alpine catchment (Riale di Ronco, Switzerland).","authors":"Andrew S Acciardo, Moira Arnet, Nima Gholizadeh Doonechaly, Alberto Ceccato, Paula Rodriguez, Hoang N H Tran, Quinn Wenning, Eric Zimmerman, Marian Hertrich, Bernard Brixel, Cara Magnabosco","doi":"10.3389/fmicb.2025.1522714","DOIUrl":"10.3389/fmicb.2025.1522714","url":null,"abstract":"<p><p>Accessing the deep terrestrial subsurface (greater than 1 km below the surface) presents significant practical challenges, leaving these ecosystems largely uncharacterized despite their extensive presence beneath Earth's landmasses. In this study, we introduce the BedrettoLab Deep Life Observatory (DELOS), a new underground laboratory to study the biogeochemical diversity of groundwater in a high-altitude Alpine catchment tens of meters to 1.6 km underground. Biogeochemical monitoring of DELOS over spatial and temporal scales highlight three dominant ecotypes throughout DELOS: (1) Shallow groundwater with low electrical conductivity enriched in <i>Leptospirillia</i>; (2) High-inflow fault zones enriched in ultra-small bacteria and archaea; (3) Bicarbonate-enriched waters that are enriched in <i>Candidatus</i> Kryptonia and <i>Spirochaetota</i>. Despite a consistent lithology throughout DELOS, groundwater from fractures that are spatially near each other are not always represented by the same ecotype and can be more similar to groundwater emitted from fractures thousands of meters away. Despite this heterogeneity, the biological and hydrochemical compositions of the groundwater of individual fractures remained relatively stable throughout the course of a 1-year monitoring period. An exception to this trend occurred after a series of seismic events near one groundwater-bearing fracture. Here, the microbial community and hydrochemical composition of the groundwater changed after the seismic events but returned to the site's \"baseline\" composition within 3 weeks. Taken together, these findings provide new insights into the spatial and temporal heterogeneity of deep subsurface ecosystems and the subsurface connectivity of an Alpine subsurface environment.</p>","PeriodicalId":12466,"journal":{"name":"Frontiers in Microbiology","volume":"16 ","pages":"1522714"},"PeriodicalIF":4.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11897985/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143614329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Composite quantile regression approach to batch effect correction in microbiome data.","authors":"Jiwon Park, Taesung Park","doi":"10.3389/fmicb.2025.1484183","DOIUrl":"10.3389/fmicb.2025.1484183","url":null,"abstract":"<p><strong>Background: </strong>Batch effects refer to data variations that arise from non-biological factors such as experimental conditions, equipment, and external factors. These effects are considered significant issues in the analysis of biological data since they can compromise data consistency and distort actual biological differences, which can severely skew the results of downstream analyses.</p><p><strong>Method: </strong>In this study, we introduce a new approach that comprehensively addresses two types of batch effects: \"systematic batch effects\" which are consistent across all samples in a batch, and \"nonsystematic batch effects\" which vary depending on the variability of operational taxonomic units (OTUs) within each sample in the same batch. To address systematic batch effects, we apply a negative binomial regression model and correct for consistent batch influences by excluding fixed batch effects. Additionally, to handle nonsystematic batch effects, we employ composite quantile regression. By adjusting the distribution of OTUs to be similar based on a reference batch selected using the Kruskal-Walis test method, we consider the variability at the OTU level.</p><p><strong>Results: </strong>The performance of the model is evaluated and compared with existing methods using PERMANOVA R-squared values, Principal Coordinates Analysis (PCoA) plots and Average Silhouette Coefficient calculated with diverse distance-based metrics. The model is applied to three real microbiome datasets: Metagenomic urine control data, Human Immunodeficiency Virus Re-analysis Consortium data, and Men and Women Offering Understanding of Throat HPV study data. The results demonstrate that the model effectively corrects for batch effects across all datasets.</p>","PeriodicalId":12466,"journal":{"name":"Frontiers in Microbiology","volume":"16 ","pages":"1484183"},"PeriodicalIF":4.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11893821/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of antimicrobial resistance via state-of-the-art technologies versus conventional methods.","authors":"Ayman Elbehiry, Eman Marzouk, Adil Abalkhail, Moustafa H Abdelsalam, Mohamed E A Mostafa, Mazen Alasiri, Mai Ibrahem, Abousree T Ellethy, Abdulaziz Almuzaini, Sahar N Aljarallah, Akram Abu-Okail, Naif Marzook, Satam Alhadyan, Husam M Edrees","doi":"10.3389/fmicb.2025.1549044","DOIUrl":"10.3389/fmicb.2025.1549044","url":null,"abstract":"<p><p>Antimicrobial resistance (AMR) is recognized as one of the foremost global health challenges, complicating the treatment of infectious diseases and contributing to increased morbidity and mortality rates. Traditionally, microbiological culture and susceptibility testing methods, such as disk diffusion and minimum inhibitory concentration (MIC) assays, have been employed to identify AMR bacteria. However, these conventional techniques are often labor intensive and time consuming and lack the requisite sensitivity for the early detection of resistance. Recent advancements in molecular and genomic technologies-such as next-generation sequencing (NGS), matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS), lateral flow immunoassays (LFIAs), PCR-based diagnostic methods, and CRISPR-based diagnostics-have revolutionized the diagnosis of AMR. These innovative approaches provide increased sensitivity, reduced turnaround times, and the ability to identify genetic resistance mechanisms. This review seeks to examine the advantages and disadvantages of both emerging technologies and traditional methods for detecting AMR, emphasizing the potential benefits and limitations inherent to each. By understanding the strengths and limitations of these technologies, stakeholders, including researchers, healthcare professionals, regulatory agencies, health authorities, financial managers, and patients, can make informed decisions aimed at preventing the emergence and dissemination of antibiotic-resistant strains, thereby ultimately increasing patient safety.</p>","PeriodicalId":12466,"journal":{"name":"Frontiers in Microbiology","volume":"16 ","pages":"1549044"},"PeriodicalIF":4.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11893576/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determining the <i>Bordetella</i> LPS structural features that influence TLR4 downstream signaling.","authors":"Kiruthika Manivannan, Yasmine Fathy Mohamed, Rachel C Fernandez","doi":"10.3389/fmicb.2025.1540534","DOIUrl":"10.3389/fmicb.2025.1540534","url":null,"abstract":"<p><p>Upon recognizing bacterial lipopolysaccharide (LPS), human TLR4 initiates two distinct signaling pathways: the MyD88 pathway from the cell surface or the TRIF pathway following endocytosis. While the first is associated with strong pro-inflammatory responses, the latter is linked to dendritic cell maturation and T cell priming. Changes in LPS structure can influence the activation of either or both pathways. This study investigates the influence of specific structural features of <i>Bordetella</i> LPS on these pathways: the O antigen, the number of acyl chains in lipid A and the glucosamine modification of the phosphates of the lipid A diglucosamine backbone. Systematically engineered <i>Bordetella</i> LPS differing in one or more of these features were studied by quantifying NFκB and IRF3 activation-indicators of MyD88 and TRIF pathway activation, respectively. The findings reveal that the glucosamine modification of lipid A plays a dominant role in TLR4-mediated signaling, overriding the influence of the O antigen and lipid A acylation. The absence of glucosamine modification significantly reduced the activation of both MyD88 and TRIF pathways, underscoring its importance in promoting TLR4 dimerization. Furthermore, under-acylation of LPS (with 4 or 5 acyl chains) partially reduced NFκB activation, while completely abrogating TRIF pathway activation. In contrast, hexa-and hepta-acylated LPS equally and robustly activated both pathways. Lastly, the <i>Bordetella</i> O antigen selectively biased signaling towards the TRIF pathway without affecting the MyD88 pathway. This study provides valuable insights into how specific LPS structural modifications can be leveraged to tailor TLR4-mediated signaling.</p>","PeriodicalId":12466,"journal":{"name":"Frontiers in Microbiology","volume":"16 ","pages":"1540534"},"PeriodicalIF":4.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects and potential pathways of goose astrovirus infection on gosling hepatic lipid metabolism.","authors":"Chao Yin, Yun Shi, Haiqin Li, Zhihua Lu, Xiaona Gao, Guoliang Hu, Xiaoquan Guo","doi":"10.3389/fmicb.2025.1531373","DOIUrl":"10.3389/fmicb.2025.1531373","url":null,"abstract":"<p><strong>Introduction: </strong>The adverse effects of goose astrovirus (GoAstV) on avian growth and health have been widely reported previously, while the stress reactions and corresponding mechanism of gosling liver responding to GoAstV infection remain not entirely clear.</p><p><strong>Methods: </strong>One-day-old goslings inoculated subcutaneously with 2 × 10^-6 TCID₅₀ of GoAstV were employed as an experimental model, and the potential effects and pathways of GoAstV infection on gosling liver functions were investigated by combining the morphological, biochemical and RNA sequencing (RNA-seq) techniques.</p><p><strong>Results: </strong>Structural and functional impairments were found in gosling livers post the virus infection, as characterized by the histological alterations in liver index and morphology of hepatic cord and sinuses, as well as the abnormal expression patterns of the cellular antioxidant, inflammation and apoptosis-related genes. RNA sequencing analysis were performed to investigate the underlying mechanism. Results showed that the analysis of screened 1949 differentially expressed genes (DEGs) were mainly enriched in GO terms related to organic immune defense and substance metabolism, and their corresponding KEGG pathways represented by PPAR signaling pathway, intestinal immune network for IgA production, and fatty acid metabolism and degradation, suggesting that the functions of avian immunity and lipid metabolism were greatly changed after the GoAstV infection. Finally, the lipid deposition in gosling hepatocytes were further demonstrated by the subsequent Oil red O staining, biochemical detection of serum TG and HDL-C, and the gene expression analysis including <i>PPARα</i>, <i>PPARγ</i>, <i>ACSBG2</i>, <i>ACSL5</i>, <i>CPT1A</i> and <i>PCK1</i>.</p><p><strong>Discussion: </strong>Though limitations exist, the findings of this study are helpful to expand our understanding about the negative effects of GoAstV on goslings, and provide us with new clues for the salvaging of GoAstV-induced liver dysfunctions in poultry industry.</p>","PeriodicalId":12466,"journal":{"name":"Frontiers in Microbiology","volume":"16 ","pages":"1531373"},"PeriodicalIF":4.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11893818/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of calcium sources on the bio-mineralization behavior of <i>Shewanella putrefaciens</i> and induced microbiologically influenced corrosion inhibition.","authors":"Yuntian Lou, Hao Zhang, Weiwei Chang, Jingzhi Yang, Xudong Chen, Xiangping Hao, Hongchang Qian, Dawei Zhang","doi":"10.3389/fmicb.2025.1532151","DOIUrl":"10.3389/fmicb.2025.1532151","url":null,"abstract":"<p><p>The influence of different calcium sources on the mineralization behavior of <i>Shewanella putrefaciens</i> and their roles in microbiologically influenced corrosion inhibition (MICI) of Q235 carbon steel were investigated. Calcium lactate, calcium nitrate, and calcium L-aspartate were selected as alternative calcium sources to assess their effects on bacterial growth, carbonate deposition, and corrosion resistance. <i>S. putrefaciens</i> exhibited stable growth in all tested media, with the pH exceeding 8 after 14 days, promoting carbonate precipitation. Under sterile conditions, all calcium sources provided some corrosion inhibition, with calcium L-aspartate demonstrating the most effective protection. In bacterial inoculated systems, calcium lactate and calcium L-aspartate facilitated the formation of a continuous CaCO₃ mineralized layer, significantly reducing corrosion, whereas calcium nitrate resulted in discontinuous carbonate deposits, promoting localized corrosion. Electrochemical impedance spectroscopy and potentiodynamic polarization analyses confirmed that the mineralized layers formed with calcium lactate and calcium L-aspartate significantly enhanced corrosion resistance, while calcium nitrate exacerbated corrosion due to nitrate-reducing bacterial activity. These findings emphasize the crucial role of calcium source selection in MICI and provide insights for optimizing microbial mineralization strategies for corrosion mitigation.</p>","PeriodicalId":12466,"journal":{"name":"Frontiers in Microbiology","volume":"16 ","pages":"1532151"},"PeriodicalIF":4.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895700/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diversity of arbuscular mycorrhizal fungi and its response to seasonal variation in alpine grassland of the eastern Tibetan Plateau.","authors":"Wanqing Dong, Tingting Ding, Tingyu Duan","doi":"10.3389/fmicb.2025.1511979","DOIUrl":"10.3389/fmicb.2025.1511979","url":null,"abstract":"<p><strong>Introduction: </strong>Arbuscular mycorrhizal (AM) fungi play a crucial role in maintaining diversity and ensuring the proper functioning of grassland ecosystems. A comprehensive understanding of the diversity, distribution patterns, and drivers of AM fungi in different habitats is essential for exploring the ecological roles in grassland ecosystems.</p><p><strong>Methods: </strong>In this study, we utilized high-throughput sequencing technology to explore the diversity of AM fungi and their distribution at an altitude of approximately 3,500 m in the alpine grassland of the eastern Tibetan Plateau. Additionally, we investigated the impacts of seasonal variation on AM fungal communities.</p><p><strong>Results: </strong>A total of 97 species of AM fungi, comprising 937 operational taxonomic units (OTUs) belong to 9 families and 10 genera, were identified from the soil samples. Notably, the genera <i>Glomus</i> and <i>Paraglomus</i> were the most abundant and dominant within the identified communities. The composition, distribution, and diversity of the AM fungal communities in the alpine grassland of the eastern Tibetan Plateau were significantly affected by seasonal variation (<i>p</i> < 0.05), with geographic distance being a determining factor. Total nitrogen (TN), soil organic matter (SOM), and pH were identified as the key soil factors driving changes in AM fungal communities.</p><p><strong>Discussion: </strong>The results demonstrated that the characteristics of AM fungal communities in the alpine grasslands of the eastern Tibetan Plateau were affected by seasonal variations and geographic location, and these findings are significant for the application of AM fungi in the restoration of grassland in similar ecosystems.</p>","PeriodicalId":12466,"journal":{"name":"Frontiers in Microbiology","volume":"16 ","pages":"1511979"},"PeriodicalIF":4.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11893506/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.","authors":"Zhenyu Zhao, Zhixi Hu, Lin Li","doi":"10.3389/fmicb.2025.1509548","DOIUrl":"10.3389/fmicb.2025.1509548","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the relationship between heart failure (HF) and gut microbiota-mediated energy metabolism, and to explore the role of Shenfu Injection in this process.</p><p><strong>Materials and methods: </strong>In this study, Adriamycin-induced chronic heart failure (CHF) rat model was used and randomly divided into the blank control group (Normal, <i>n</i> = 9), HF control group (Model, <i>n</i> = 12), Shenfu Injection treatment group (SFI, <i>n</i> = 9), and positive drug control group (TMZ, <i>n</i> = 9). The changes in gut microbiota structure were analyzed by 16S rRNA high-throughput sequencing, the content of short-chain fatty acids (SCFAs) was detected by targeted metabolomics technology, and cardiac function and energy metabolism-related indicators were evaluated.</p><p><strong>Results: </strong>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.</p><p><strong>Conclusion: </strong>Shenfu Injection in treating HF may improve myocardial energy metabolism and intestinal health by regulating gut microbiota, especially the abundance of SCFAs-producing bacteria Akkermansia and Blautia, thereby exerting therapeutic effects. This provides theoretical support for treatment strategies based on gut microbiota.</p>","PeriodicalId":12466,"journal":{"name":"Frontiers in Microbiology","volume":"16 ","pages":"1509548"},"PeriodicalIF":4.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum: The effect and mechanism of volatile oil emulsion from leaves of <i>Clausena lansium</i> (Lour.) Skeels on <i>Staphylococcus aureus in vitro</i>.","authors":"Yan-Na Guo, Ke-Ren He, Shao-Shan Liang, Rui-Wei Mou, Meng-Han Lu, Yong-Ming He, Lu-Ping Tang","doi":"10.3389/fmicb.2025.1575361","DOIUrl":"https://doi.org/10.3389/fmicb.2025.1575361","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.3389/fmicb.2024.1376819.].</p>","PeriodicalId":12466,"journal":{"name":"Frontiers in Microbiology","volume":"16 ","pages":"1575361"},"PeriodicalIF":4.0,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11893863/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}