{"title":"Biosynthesis of polyhydroxyalkanoates from styrene by Enterobacter spp. isolated from polluted environment","authors":"A. Arshad, Bisma Ashraf, I. Ali, N. Jamil","doi":"10.1007/s11515-017-1446-2","DOIUrl":"https://doi.org/10.1007/s11515-017-1446-2","url":null,"abstract":"","PeriodicalId":12454,"journal":{"name":"Frontiers in Biology","volume":"12 1","pages":"210-218"},"PeriodicalIF":0.0,"publicationDate":"2017-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11515-017-1446-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43778343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How to manage rheumatoid arthritis according to classic biomarkers and polymorphisms?","authors":"K. Mowla, M. Saki, M. Jalali, Z. Zayeri","doi":"10.1007/s11515-017-1452-4","DOIUrl":"https://doi.org/10.1007/s11515-017-1452-4","url":null,"abstract":"","PeriodicalId":12454,"journal":{"name":"Frontiers in Biology","volume":"12 1","pages":"183-191"},"PeriodicalIF":0.0,"publicationDate":"2017-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11515-017-1452-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43304491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Boustani, S. Pakseresht, M. Haghdoust, Saeid Qanbari, Hadis Mehregan-Nasab
{"title":"Effect of psychological preparation on anxiety level before colonoscopy in outpatients referred to Golestan Hospital in Ahvaz","authors":"H. Boustani, S. Pakseresht, M. Haghdoust, Saeid Qanbari, Hadis Mehregan-Nasab","doi":"10.1007/s11515-017-1451-5","DOIUrl":"https://doi.org/10.1007/s11515-017-1451-5","url":null,"abstract":"","PeriodicalId":12454,"journal":{"name":"Frontiers in Biology","volume":"12 1","pages":"235-239"},"PeriodicalIF":0.0,"publicationDate":"2017-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11515-017-1451-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42659914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Kar, P. Basak, S. Sen, R. Ghosh, M. Bhattacharyya
{"title":"Analysis of curcumin interaction with human serum albumin using spectroscopic studies with molecular simulation","authors":"T. Kar, P. Basak, S. Sen, R. Ghosh, M. Bhattacharyya","doi":"10.1007/s11515-017-1449-z","DOIUrl":"https://doi.org/10.1007/s11515-017-1449-z","url":null,"abstract":"","PeriodicalId":12454,"journal":{"name":"Frontiers in Biology","volume":"12 1","pages":"199-209"},"PeriodicalIF":0.0,"publicationDate":"2017-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11515-017-1449-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43246346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Inhibition and attenuation of pathogenicity of Porphyromonas gingivalis by leupeptin: A review","authors":"H. Jain","doi":"10.1007/s11515-017-1442-6","DOIUrl":"https://doi.org/10.1007/s11515-017-1442-6","url":null,"abstract":"","PeriodicalId":12454,"journal":{"name":"Frontiers in Biology","volume":"12 1","pages":"192-198"},"PeriodicalIF":0.0,"publicationDate":"2017-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11515-017-1442-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48001661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Mohanasrinivasan, A. Mohanapriya, S. Potdar, S. Chatterji, S. Konne, S. Kumari, S. M. Keziah, C. Subathra Devi
{"title":"In vitro and in silico studies on fibrinolytic activity of nattokinase: A clot buster from Bacillus sp.","authors":"V. Mohanasrinivasan, A. Mohanapriya, S. Potdar, S. Chatterji, S. Konne, S. Kumari, S. M. Keziah, C. Subathra Devi","doi":"10.1007/s11515-017-1453-3","DOIUrl":"https://doi.org/10.1007/s11515-017-1453-3","url":null,"abstract":"","PeriodicalId":12454,"journal":{"name":"Frontiers in Biology","volume":"12 1","pages":"219-225"},"PeriodicalIF":0.0,"publicationDate":"2017-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11515-017-1453-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45503372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Frontiers in BiologyPub Date : 2017-06-01Epub Date: 2017-03-04DOI: 10.1007/s11515-017-1443-5
Andrew Brandmaier, Sheng-Qi Hou, Sandra Demaria, Silvia C Formenti, Wen H Shen
{"title":"PTEN at the interface of immune tolerance and tumor suppression.","authors":"Andrew Brandmaier, Sheng-Qi Hou, Sandra Demaria, Silvia C Formenti, Wen H Shen","doi":"10.1007/s11515-017-1443-5","DOIUrl":"https://doi.org/10.1007/s11515-017-1443-5","url":null,"abstract":"<p><strong>Background: </strong>PTEN is well known to function as a tumor suppressor that antagonizes oncogenic signaling and maintains genomic stability. The <i>PTEN</i> gene is frequently deleted or mutated in human cancers and the wide cancer spectrum associated with PTEN deficiency has been recapitulated in a variety of mouse models of <i>Pten</i> deletion or mutation. <i>Pten</i> mutations are highly penetrant in causing various types of spontaneous tumors that often exhibit resistance to anticancer therapies including immunotherapy. Recent studies demonstrate that PTEN also regulates immune functionality.</p><p><strong>Objective: </strong>To understand the multifaceted functions of PTEN as both a tumor suppressor and an immune regulator.</p><p><strong>Methods: </strong>This review will summarize the emerging knowledge of PTEN function in cancer immunoediting. In addition, the mechanisms underlying functional integration of various PTEN pathways in regulating cancer evolution and tumor immunity will be highlighted.</p><p><strong>Results: </strong>Recent preclinical and clinical studies revealed the essential role of PTEN in maintaining immune homeostasis, which significantly expands the repertoire of PTEN functions. Mechanistically, aberrant PTEN signaling alters the interplay between the immune system and tumors, leading to immunosuppression and tumor escape.</p><p><strong>Conclusion: </strong>Rational design of personalized anti-cancer treatment requires mechanistic understanding of diverse PTEN signaling pathways in modulation of the crosstalk between tumor and immune cells.</p>","PeriodicalId":12454,"journal":{"name":"Frontiers in Biology","volume":"12 3","pages":"163-174"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11515-017-1443-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35901839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cationic antimicrobial peptide: LL-37 and its role in periodontitis","authors":"H. Jain","doi":"10.1007/s11515-017-1432-8","DOIUrl":"https://doi.org/10.1007/s11515-017-1432-8","url":null,"abstract":"","PeriodicalId":12454,"journal":{"name":"Frontiers in Biology","volume":"12 1","pages":"116-123"},"PeriodicalIF":0.0,"publicationDate":"2017-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11515-017-1432-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45183527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tcf1 at the crossroads of CD4+ and CD8+ T cell identity","authors":"Jodi A. Gullicksrud, Q. Shan, Hai-hui Xue","doi":"10.1007/s11515-017-1445-3","DOIUrl":"https://doi.org/10.1007/s11515-017-1445-3","url":null,"abstract":"","PeriodicalId":12454,"journal":{"name":"Frontiers in Biology","volume":"12 1","pages":"83-93"},"PeriodicalIF":0.0,"publicationDate":"2017-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11515-017-1445-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47750726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}