{"title":"[Changes in the blink reflex in patients with essential blepharospasm and hemifacial spasm].","authors":"P Roggenkämper, R Laskawi, W Damenz, M Schröder","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Electrophysiological investigations have been carried out in 46 patients with essential blepharospasm and 41 with hemifacial spasm. In both diseases reproducible pathologic alterations in the blink reflex were found. In essential blepharospasm a direct R1/R2 transition and a contralateral early component with and without direct transition into the R2C component were recorded. In patients with hemifacial spasm there was a loss of the R1 component in addition. In repeated treatments with botulinum toxin the amplitude (R1,R2) of the blink reflex was reduced in some cases, although in some cases the intensity of spasm was as high as before treatment once the effect had faded.</p>","PeriodicalId":12437,"journal":{"name":"Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft","volume":"88 4","pages":"411-5"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12948956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B Bertram, S Wolf, F Kaufhold, F Jung, H Kiesewetter, M Reim
{"title":"[Rheologic findings in patients with diabetic retinopathy].","authors":"B Bertram, S Wolf, F Kaufhold, F Jung, H Kiesewetter, M Reim","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The rheological parameters hematocrit, plasma viscosity, red blood cell aggregation and blood cell rigidity were measured in 256 adult-onset (type II) diabetics. The stage of diabetic retinopathy was graded by means of ophthalmoscopy and videofluorescein angiography. The mean values of hematocrit (men 45 +/- 5%, women 42 +/- 5%) and red blood cell rigidity (1.01 +/- 0.08) were equal to those in normal subjects. Plasma viscosity (1.40 +/- 0.10) mPas, normals: 1.24 +/- 0.05 mPas) and red blood cell aggregation (16.0 +/- 4.2, normals: 14.6 +/- 3.2) were increased over the values in normals. The groups with different stages of diabetic retinopathy showed no difference in all rheological parameters. Plasma viscosity and red blood cell aggregation were determined partly by the levels of the large plasma proteins. In the type II diabetics fibrinogen was the most markedly elevated large plasma protein (4.1 +/- 1.2 g/l, normals: 3.2 +/- 0.6 g/l). Significant correlations were found between plasma viscosity and fibrinogen (0.49); plasma viscosity and alpha-2-macroglobulin (0.33); red blood cell aggregation and alpha-2-macroglobulin (0.28); and red blood cell aggregation and immunoglobulin M (0.25). The elevation of red blood cell aggregation and plasma viscosity may be one of the reasons for disturbed microcirculation and fundus changes in diabetic retinopathy.</p>","PeriodicalId":12437,"journal":{"name":"Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft","volume":"88 4","pages":"321-5"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12949226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Epiphora as the leading symptom of Urbach-Wiethe syndrome in a sibling pair].","authors":"H L Knorr, H F Meythaler, G O Naumann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Urbach-Wiethe-Syndrom. syn. Hyalinosis cutis et mucosae is a rare, probably autosomal-recessively inherited disease. In the first weeks of life it begins with typical hoarness due to hyalin deposits in larynx and with increasing age leads to different changes in mucous membrane and later on in cutis. Etiology and pathogenesis are unknown. The treatment is only symptomatic. In our casuistic we present two sisters, who are constantly full of tears. Either show different stage of the typical representation of Hyalinosis cutis et mucosae. We demonstrate progression and penetrance of the disease and clinical alterations in eyes, skin and mucous membrane.</p>","PeriodicalId":12437,"journal":{"name":"Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft","volume":"88 2","pages":"168-72"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13016398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Effect of vasoconstrictor eyedrops on tear volume and tear secretion].","authors":"M Göbbels, C Achten, M Spitznas","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Vasoconstrictive, alpha-sympathicomimetic eye drops are ophthalmic drugs that are extensively used. However, patients often complain of typical dry eye symptoms, especially after long-lasting application of such eye drops. In the present study, the effect of sympathicomimetic eye drops (oxymetazoline 0.026%) on the tear volume and tear flow of 16 healthy individuals was determined quantitatively by means of objective fluorophotometry. Both tear volume and tear flow were found to be significantly (p less than 0.001) decreased 3 h after instillation (tear volume: -52%; tear flow: -31%). Thus, alpha-sympathicomimetic eye drops containing oxymetazoline 0.026% lead to marked and protracted decrease in tear volume and tear flow. After frequent or long-lasting application, this fact may be responsible for severe dry eye conditions.</p>","PeriodicalId":12437,"journal":{"name":"Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft","volume":"88 2","pages":"173-5"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13016399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Ocular motility disorders after retinal surgery].","authors":"C A Lawin-Brüssel, B Anhalt, H Markodimitrakis","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Motility disturbances after retinal detachment surgery are rare complications. This retrospective study examined 2427 cases from the University Eye Hospital in Münster (1/84-6/89). All cases underwent scleral buckling procedures for retinal detachment. Twelve patients developed persistent diplopia. The scleral buckle needed to be removed in all cases; however, additional strabismus surgery had to be done in 5 cases to restore binocular single vision. Evaluation of the 12 cases suggested that the complications were caused by hypertrophic scarring rather than by the buckles, suturing material or muscular decompensation.</p>","PeriodicalId":12437,"journal":{"name":"Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft","volume":"88 2","pages":"182-5"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13016402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Clinical and experimental results with a new fully automatic self-tonometer].","authors":"J Draeger, R Schwartz, C Deutsch, S Groenhoff","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In a clinical study 25 patients being treated at the Department of Ophthalmology in the Hamburg University were instructed in self-tonometry using a new automatic tonometer. In a first sequence, three self-measurements were taken by the patients within 1 min; then a control measurement with a motor-driven hand applanation tonometer (HAT) was taken by a physician. The procedure was repeated 6-10 min afterwards without new local anesthesia. In addition, a dynamometer was applied to 5 healthy eyes in order to test the self-tonometer at higher pressure levels. The correlation of repetitive measurements of the self-tonometer showed good results for the patient measurements (r1 = 0.97, SD1 = 1.66 mmHg, r2 = 0.96, SD2 = 1.47 mmHg) and slightly worse values for the measurements with the dynamometer (r3 = 0.97, SD3 = 2.02 mmHg), probably due to the non-physiological deformation of the eye induced by the dynamometer. To establish accuracy, the results were compared to the HAT. The following results were achieved: (r1 = 0.97, s1 = 1.71 mmHg, r2 = 0.96, s2 = 1.49 mmHg, r3 = 0.97, s3 = 2.69 mmHg). Other studies with the self-tonometer will follow in order to optimize its accuracy and design. Self-tonometry under conditions of microgravity is planned for the 2nd German Spacelab Mission and the Russian Space station MIR. In the future, self-tonometry will play an important part in the management of glaucoma.</p>","PeriodicalId":12437,"journal":{"name":"Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft","volume":"88 3","pages":"304-7"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13050455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Reference values for quantitative image analysis of indocyanine green video-fluorescence angiography].","authors":"C Prünte","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Indocyanine green video-fluorescence angiography was performed in 46 healthy normal subjects between the ages of 20 and 81 years using a 30 degrees Zeiss fundus camera, an external light supply and a high resolution CCD camera. Pictures were directly stored in a picture analysis system based on a PC with a temporal resolution of 25 pictures per second. Using statistical picture analysis, choroidal blood-flow parameters were obtained in a round area of interest with a diameter of 8 degrees with the center in the fovea. The parameters include: the mean arterial filling time (AFT) and the mean capillary density (MCD) in the choroid. There was no correlation for one of these parameters with arterial blood pressure or intraocular pressure. All values for the AFT were on an equal level for normal subjects younger than 65 years. Older normal subjects in some cases had clearly increased arterial filling times. The density of the capillary network in the choroid was significantly reduced with increasing age, and there was reduced density of the capillary network in normals with myopia.</p>","PeriodicalId":12437,"journal":{"name":"Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft","volume":"88 3","pages":"233-5"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13050502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Limbal transplantation for ocular surface reconstruction--a review.","authors":"S C Tseng, R J Tsai","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Based on the new concept that the limbal epithelium contains the stem cell population for corneal epithelial cellular proliferation and differentiation, a surgical procedure, limbal transplantation, has been devised. This paper reviews the background information regarding how this procedure was originally developed and the encouraging clinical as well as experimental results of corneal surface reconstruction using this procedure. The clinical aspects are also discussed concerning the surgical indications, procedural details, expected results, and potential problems. We also include the recent results using a rabbit model to compare the efficacy of surface reconstruction between limbal transplantation and original conjunctival transplantation. We hope, through this up-to-date review, that our capacities to manage these and other ocular surface disorders will be enhanced by understanding the new important concept of the limbal stem cell.</p>","PeriodicalId":12437,"journal":{"name":"Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft","volume":"88 3","pages":"236-42"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13050503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O Arend, S Wolf, K Schulte, F Jung, B Bertram, M Reim
{"title":"[Conjunctival microcirculation and hemorheology in patients with venous occlusions of the retina].","authors":"O Arend, S Wolf, K Schulte, F Jung, B Bertram, M Reim","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Forty-two patients with branch vein or central retinal vein occlusion were enrolled in this randomized placebo-controlled study. We studied the influence of hemodilution therapy with hydroxyethyl-starch (HAES-steril) combined with pentoxifylline (Trental) for 6 months. In the bulbar conjunctiva, capillary red blood cell (RBC) velocities and vessel diameters and rheological parameters of hematocrit, erythrocyte aggregation and plasma viscosity were examined. In the hemodilution group we observed no changes in vessel diameter and a significant increase in RBC velocity after therapy. After 6 weeks the RBC velocity showed 30% higher values but there was no statistically significant difference. After hemodilution therapy hematocrit, erythrocyte aggregation and plasma viscosity were significantly different from those in the control group. After 6 weeks we observed significant differences only in erythrocyte aggregation. This examination verifies the positive influence of hemodilution therapy on microcirculation and hemorheology.</p>","PeriodicalId":12437,"journal":{"name":"Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft","volume":"88 3","pages":"243-7"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13050504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[\"Lateralis splitting\" in total oculomotor paralysis with trochlear nerve paralysis].","authors":"H Kaufmann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In two cases of 3rd nerve palsy and trochlear palsy we performed a new transposition procedure. This procedure consists of splitting of the lateral rectus muscle and transposition of the upper half to a retroequatorial point near the nasal superior vortex vein. The lower half is transposed to a retroequatorial point near the nasal inferior vortex vein. In the first case we linked the two halves with fascia late. The horizontal deviation was diminished by 15-20 degrees.</p>","PeriodicalId":12437,"journal":{"name":"Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft","volume":"88 3","pages":"314-6"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13051076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}