Bulletin of the Club of Pancreatologists最新文献

{"title":"The problems of delayed diagnostics of neuroendocrine tumors of the gastrointestinal tract and pancreas (clinical case)","authors":"L. G. Vologzhanina, I. Petukhova","doi":"10.33149/vkp.2018.03.07","DOIUrl":"https://doi.org/10.33149/vkp.2018.03.07","url":null,"abstract":"Gastrinoma is a rare neuroendocrine tumor, with frequent cases of late detection. A clinical case of late diagnostics of gastrinoma complicated by metastases is presented, with symptomatology remaining after surgical treatment, which is stopped with the help of proton pump inhibitors.","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133604056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolic acidosis as an important factor of pathogenesis of chronic pancreatitis","authors":"O. S. Zemlyak, L. Babinets","doi":"10.33149/VKP.2018.03.03","DOIUrl":"https://doi.org/10.33149/VKP.2018.03.03","url":null,"abstract":"Article presents the results of the analysis of scientific literature on the role of metabolic acidosis in the pathogenesis of chronic pancreatitis. It is stated that metabolic acidosis is an important predictive factor in the formation and deepening of trophic insufficiency, which further reduces the quality of life of patients with chronic pancreatitis and worsens the prognosis. This motivates the need to take into account the presence of metabolic acidosis during the development of a complex treatment program for such patients.","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115746067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastroesophageal reflux disease: current state of the problem and prospects","authors":"Y. Tsimmerman, L. G. Vologzhanina","doi":"10.33149/VKP.2018.03.08","DOIUrl":"https://doi.org/10.33149/VKP.2018.03.08","url":null,"abstract":"The article is a lecture for doctors which includes modern ideas about gastroesophageal reflux disease: its etiology and pathogenesis, risk factors, clinical features and diagnostics. The classification, strategy and tactics of treatment are explained in detail. The author critically evaluated the literature data and expressed his reasoned critical point of view concerning the basic concepts, diagnostics and treatment of the disease.","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"211 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123532262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What is common between functional dyspepsia and bacterial overgrowth syndrome","authors":"E. Plotnikova, Y. Zakharova, T. Gracheva","doi":"10.33149/vkp.2018.03.09","DOIUrl":"https://doi.org/10.33149/vkp.2018.03.09","url":null,"abstract":"The article presents the results of a review of various syndromes that occur in the pathology of the digestive system. Functional dyspepsia and the principles of its treatment are considered in detail. Proton pump inhibitors are one of the main groups of drugs used to treat functional dyspepsia. A serious complication of prolonged use of proton pump inhibitors is the syndrome of small intestinal bacterial overgrowth. The main principles of treatment of this complication are antibacterial therapy and probiotics. Enterobseptic Novobismol® and modern probiotic Maxilak® can be drugs of choice in this situation.","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123844474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First use of ultrasound elastography in differential diagnostics of pancreatic cystic lesions","authors":"T. Dibina, A. Koshel, Y. S. Drozdov, S. Klokov","doi":"10.33149/VKP.2018.03.06","DOIUrl":"https://doi.org/10.33149/VKP.2018.03.06","url":null,"abstract":"Aim is to evaluate the effectiveness of ultrasonic elastography in the differential diagnostics of pancreatic cystic lesions. \u0000Materials and methods. Seventy patients with pancreatic cystic lesions were examined. Structure of clinical forms: serous cystadenoma – 2, mucinous cystadenoma – 2, mucinous cystadenocarcinoma – 2, highly differentiated endocrine functionally inactive cystic tumor – 1, solid pseudopapillary tumor – 1, mixed sero-neuroendocrine neoplasia – 1, pseudocyst – 61. Diagnosis of cystic pancreatic formations was stated with the help of transabdominal ultrasound examination (with 3D reconstruction) and ultrasonic elastography. \u0000Results. The parameters of ultrasonic elastography for various types of cystic pancreatic formations were determined. Sensitivity, specificity, prognosticity of the positive result, predictability of the negative result, the overall accuracy of the technique were 97%, 75%, 74%, 97% and 84%, respectively. The AUC value (the area bounded by the ROC curve) for ultrasonic elastography was 0.93 (P=0.028). \u0000Conclusions. Ultrasonic elastography is an effective, non-invasive technique of differential diagnostics of cystic pancreatic formations and can be widely used in clinical practice.","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133901937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New systems for assessing severity and predicting outcomes of acute pancreatitis","authors":"A. Litvin, A. A. Filatov, S. Sychev, A. S. Prokoptsov","doi":"10.33149/vkp.2018.03.01","DOIUrl":"https://doi.org/10.33149/vkp.2018.03.01","url":null,"abstract":"The article is a review of the literature on new systems for assessing the severity and predicting the outcomes of acute pancreatitis. The authors cite current literature data on the effectiveness of various new scales, as well as information on developed systems that undergo a clinical information test in determining the severity of acute pancreatitis.","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133940144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enzyme replacement therapy, life quality and expectancy of patients with chronic pancreatitis and exocrine pancreatic insufficiency","authors":"N. Gubergrits, N. Byelyayeva, А. Y. Klochkov, G. Lukashevich, P. Fomenko, V. S. Rachmetova","doi":"10.33149/VKP.2018.03.02","DOIUrl":"https://doi.org/10.33149/VKP.2018.03.02","url":null,"abstract":"The article reviews the evidence-based studies devoted to the evaluation of the efficacy and safety of enzyme replacement therapy in patients with chronic pancreatitis with exocrine pancreatic insufficiency. Particular attention is paid to the effect of replacement therapy on the life quality and expectancy of patients. It has been proven that the correct prescription of enzyme preparations (minimicrosphere enteric-coated preparation, adequate dosage) improves the quality and prolongs the life of patients.","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129727014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic pancreatitis in patients with coronary heart disease: a lipid spectrum of blood, a possibility of correction","authors":"T. Hristich, D. O. Gontsariuk","doi":"10.33149/VKP.2018.03.05","DOIUrl":"https://doi.org/10.33149/VKP.2018.03.05","url":null,"abstract":"Aim of research is to evaluate significance of changes in the lipid spectrum of blood in patients with chronic pancreatitis with coronary heart disease in the pathogenesis of the comorbidity of these diseases and in the dynamics of treatment with polycosanol. \u0000Materials and methods. The study was conducted in 22 patients (10 patients with chronic pancreatitis and dyslipidemia, 12 patients with comorbidity of chronic pancreatitis and coronary heart disease in CHD II-II A-B syndrome of stage II-III functional class) and in 10 almost healthy individuals. There were 13 men, 9 women, 31–69 years old. Patients of two groups in addition to protocol treatment were prescribed polycosanol 10 mg 1 time in the evening during dinner, up to 3 months. To study the characteristics of the lipid spectrum of the blood, the level of total cholesterol, high-density lipoprotein cholesterol, triglycerols was determined (using the Zlatix-Zack-based Lachema reagents (Czech Republic)). The level of low-density lipoprotein cholesterol was determined using the Friedewald calculation method, taking into account that the triglycerol concentration did not exceed 4.5 mmol/l. In addition, very low density lipoprotein cholesterol and an atherogenicity index were determined using conventional calculation methods. \u0000Results. In patients with a combined course of chronic pancreatitis with coronary heart disease, in most cases there is a significant (p<0.05) increase in total cholesterol, low and very low-density lipoproteins and triglycerols. When analyzing the types of dyslipidemia, it was found that ІІа and ІІв types were more common (22 і 25%, respectively), but with comorbidity ІІ and ІV type of dyslipidemia was more often detected. In the dynamics of a three-month treatment with polycosanol in patients with chronic pancreatitis, the cholesterol levels of high-density lipoproteins increased significantly and the triglycerol values ​​significantly decreased, indicating a hypolipidemic effect of the drug and the possibility of using it in combination with statins in order to reduce the risk of cardiovascular events. \u0000Conclusion. The comorbidity of chronic pancreatitis with ischemic heart disease increases the risk of progression of dyslipidemia and atherosclerosis. This is confirmed by an increased atherogenic index in this group of patients, along with the severity of lipid spectrum disorders. The addition of polycosanol to patients with chronic pancreatitis and dyslipidemia, as well as in combination with coronary heart disease, contributes to the reduction and normalization of certain parameters of the lipid spectrum of the blood. This allows us to recommend a drug for long-term treatment of these groups of patients, including in combination with statin therapy.","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114655674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wilson’s disease — hepatocerebral dystrophy","authors":"Y. Tsimmerman","doi":"10.33149/VKP.2018.02.08","DOIUrl":"https://doi.org/10.33149/VKP.2018.02.08","url":null,"abstract":"The article presents a detailed review of modern ideas on Wilson’s disease – hepatocerebral dystrophy. The definition, terminology, history of the study of the disease are stated. Special attention is paid to the analysis of the pathogenesis of hepatocerebral dystrophy, including the genetic basis of its development, the disturbance of copper metabolism. The clinical picture is thoroughly described, taking into account the characteristics of liver lesion and extrahepatic manifestations, diagnostics, classification. Particular attention is paid to the means of pathogenetic and symptomatic treatment.","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122729770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post-infectious irritable bowel syndrome","authors":"E. Plotnikova","doi":"10.33149/vkp.2018.02.09","DOIUrl":"https://doi.org/10.33149/vkp.2018.02.09","url":null,"abstract":"Data on prevalence and etiopathogenesis of development of a post-infectious irritable bowel syndrome are provided in the article, the main manifestations of this disease and methods of their diagnostics are described. Treatment tactics is considered in details, the application of probiotics both for prevention, and for therapy of the described disease is being emphasized. Different studies on the related subject are presented.","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131195648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}