Bulletin of the Club of Pancreatologists最新文献

{"title":"Bowel diseases: controversial terminology problems and classification","authors":"Y. Tsimmerman","doi":"10.33149/VKP.2018.04.08","DOIUrl":"https://doi.org/10.33149/VKP.2018.04.08","url":null,"abstract":"The article discusses the terminology of chronic bowel diseases, advantages and disadvantages of the terms \"enteritis\", \"colitis\", \"enteropathy\", and \"colopathy\". It is emphasized that upon functional diseases of the intestine there are always morphological changes explaining bowel disorders. According to etiology, pathogenesis, localization of the process, presence of clinical syndromes, a detailed classification of diseases of the small and large intestines is presented. The pathogenesis of bowel diseases is discussed corresponding to the names of certain pathologies.","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125427511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From edematous syndrome to the diagnosis of \"intestinal lymphangiectasia\" (clinical observation of a rare disease)","authors":"N. Gubergrits, K. Y. Linevskaya, K. Voronin","doi":"10.33149/VKP.2018.04.10","DOIUrl":"https://doi.org/10.33149/VKP.2018.04.10","url":null,"abstract":"The article presents differential diagnostic approaches to the verification of intestinal lymphangiectasia in a patient with edematous syndrome; features of the clinical picture, diagnosis, treatment and prognosis of intestinal lymphangiectasia are shown.","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127180437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peculiarities of clinical course of osteoarthritis combined with type 2 diabetes mellitus, obesity and hypertension","authors":"Y. Serdulets","doi":"10.33149/VKP.2018.04.06","DOIUrl":"https://doi.org/10.33149/VKP.2018.04.06","url":null,"abstract":"The aim of paper is to study the clinical indices of articular syndrome in patients with osteoarthritis combined with type 2 diabetes mellitus, obesity and hypertension. It has been found out that the combined course of osteoarthritis, abdominal obesity and type 2 diabetes mellitus is accompanied by the intensified pain syndrome in the joints, a disruption of the motor function as well as the daily activities of patients.","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123043940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Features of pharmacotherapy of chronic pancreatitis (literature review)","authors":"D. Hontsariuk","doi":"10.33149/vkp.2018.04.03","DOIUrl":"https://doi.org/10.33149/vkp.2018.04.03","url":null,"abstract":"The aim of literature review is to present modern approaches to the treatment of pain syndrome in chronic pancreatitis, the effects of drug therapy, pharmacotherapeutic features of the mechanisms of the drugs effect on the pancreatic exocrine function insufficiency. \u0000 Attention is paid to the conditions of use of substitution therapy, dosing of enzyme preparations and indications for their prescription. A differentiated approach to the prescription of drugs correcting the state of the microbiocenosis of small and large intestines is proposed.","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131734203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic pancreatitis: differential diagnosis of pain with a syndrome approach treatment","authors":"T. Hristich, D. Hontsariuk","doi":"10.33149/VKP.2018.04.04","DOIUrl":"https://doi.org/10.33149/VKP.2018.04.04","url":null,"abstract":"The aim of literature review is to highlight the essential problem of internal medicine – a differential diagnosis of abdominal pain syndrome in chronic pancreatitis. \u0000Features of the clinical picture of abdominal pain in the main diseases of internal medicine are presented. The effectiveness of laboratory and modern instrumental diagnostic methods and their significance in tactics and treatment strategies are discussed in detail.","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122339249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of psychosomatic factors in the formation of diseases of the digestive system","authors":"E. Plotnikova, T. Gracheva, Y. V. Moskvina","doi":"10.33149/vkp.2018.04.09","DOIUrl":"https://doi.org/10.33149/vkp.2018.04.09","url":null,"abstract":"Psychosomatic disorders are frequent in gastroenterological practice. Visceral pain and motor-evacuation disorders of the gastrointestinal tract is a common symptom of functional gastrointestinal disorders which have a multifactorial etiology. Many patients with these diseases have comorbid behavioral disorders, such as anxiety or depression, and functional gastrointestinal disorders are described as disorders of the “gastrointestinal tract-brain” axis. Chronic stress can change the central pattern of pain, as well as motor activity and permeability of the gastrointestinal tract. The multidirectional treatment for these diseases should include psychotropic drugs and groups of somatic antipsychotics and antidepressants.","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134115388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanisms of implementation of osteopenic conditions in patients with combined course of chronic pancreatitis and hypertensive disease","authors":"T. Viun","doi":"10.33149/VKP.2018.04.05","DOIUrl":"https://doi.org/10.33149/VKP.2018.04.05","url":null,"abstract":"The comorbidity of chronic pancreatitis (CP) and hypertensive disease (HD), which are often combined with each other, can be considered as predictor states of the complication formation. This is due to the intersection of individual pathogenic links, which are enhanced by their combination. As such a complication, it is possible to consider osteoporotic conditions, leading to metabolic disturbances of bone tissue with quantitative and qualitative changes. The emergence of secondary osteoporosis (SO) is not only phenotypically but also genetically conditioned, which is the basis for studying the gene aberrations of “osteopenically directed genes” and determining the content of SO biochemical markers. \u0000Aim of study: to establish the features of the comorbid course of CP and hypertension, to optimize the diagnosis of osteoporotic conditions by studying the content of biochemical markers of OP (total acid phosphatase (TAP) and tartrate-resistant acid phosphatise (TRAP)) and polymorphism of the vitamin D receptor genes (VDR). \u0000Materials and methods of research. To solve this problem, 110 patients with CP were examined and further divided into 2 groups: treatment group — 70 persons with CP and hypertensive disease (HD), and the comparison group — 40 patients with isolated CP. These groups were representative by age and sex. The condition of bone tissue was studied in assessing the content of indicators of total acid phosphatase (TAP) and non-prostatic acid phosphatase (TRAP) in blood serum. At the same time, VDR was determined. \u0000Results. It was found that the vast majority of patients in the treatment group (84.3%) had an unfavourable B-allele; against the comparison group — 77.5% of events. Changes in the VDR gene polymorphism affected the incidence of the osteoarticular system (CCP, χ2 = 20.81, p <0.01) and had a statistically significant relationship in the distribution of alleles between groups (CCP, χ2 = 30.08, p <0.01). The parameters of TAP and TRAP in patients with combined course of HP and CP were 8.7 ± 2.3 U/L and 5.1 ± 2.3 U/L, respectively, and in the comparison group — 6.9 ± 3.0 U/L and 3.5 ± 2.1 U/L. Thus, the content of TAP and TRAP exceeded the control in the treatment group by 2.5 (TAP) and 1.9 (TRAP) times (p<0.01) and in the comparison group by 2.0 (TAP) and 1.3 TRAP) times (p<0.01), which allowed us to state the development of osteopenic conditions. The distribution of alleles of the VDR gene was characterized by the predominance of the B-allele and was “supported” by changes in the biochemical markers of osteoporosis, which led to the development of osteopenicconditions in such individuals. Thus, the combination of HP and CP is an unfavourable factor in the development of osteoporosis and the basis for early detection of osteoporetic changes. \u0000Conclusions. In the combined course of CP and arterial hypertension, there is an increase in the number of persons with the B-allele of the VDR gene (84.3% of cases), the carriers of which ha","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131084162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New data on the immunohistochemical and morphological characteristics of ductal pancreatic adenocarcinoma","authors":"Y. Y. Rakina, M. V. Zav’yalova, N. V. Krakhmal, A. Koshel, S. Afanasyev, S. Vtorushin, S. Klokov","doi":"10.33149/VKP.2018.04.07","DOIUrl":"https://doi.org/10.33149/VKP.2018.04.07","url":null,"abstract":"In recent years, especially in developed countries, there has been an increase in the incidence of pancreatic cancer. Only 20% of tumors at the time of diagnosis are evaluated as resectable, but in these cases, the prognosis of the disease is unfavorable. The overall 5-year survival rate does not exceed 5%. \u0000Pancreatic cancer was described in the 1760s by Giovanni Battista Morgagni in his classic book “De Sedibus et Causis Morborum per Anatomen Indigatis”. Over the next 200 years, pathologists significantly improved our understanding of the macro- and microscopic features of this disease. At the same time, morphological research remained the basis of diagnostics for centuries. The introduction of immunohistochemical studies into clinical practice in the late 1970s and early 1980s radically changed our approach to diagnosing this disease. Evaluation of morphological features, as well as features of expression of markers that determine the invasive potential of such neoplasms, can serve in the future as a fundamental basis in solving questions concerning possible factors of prognosis upon malignant tumors of such a localization. \u0000Aim of research — to study the morphological and immunohistochemical features of ductal pancreatic adenocarcinoma. \u0000Materials and methods. The study included 84 patients with pancreatic cancer T1-4N0-2M0-1 stage, aged from 37 to 83, who underwent surgical treatment. Morphological study of the operating material was carried out. The condition for inclusion in the study was a histotype of the tumor, namely ductal pancreatic adenocarcinoma. Posting of the material, preparation of histological preparations, coloring, immunohistochemical examination were carried out according to a standard procedure. \u0000Results and conclusion. The study made it possible to characterize the tumor morphology, as well as the features of expression of markers associated with more evident invasive characteristics of the tumor. The results of this work may be of interest in terms of their further comparison with the parameters of various forms of progression upon pancreatic cancer.","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130951908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"News of European pancreatology (by materials of the 50th meeting of European Pancreatic Club)","authors":"N. Gubergrits, N. Byelyayeva, G. Lukashevich, A. Klochkov, P. Fomenko, L. Yaroshenko, A. Yuryeva, V. Rakhmetova","doi":"10.33149/VKP.2018.04.01","DOIUrl":"https://doi.org/10.33149/VKP.2018.04.01","url":null,"abstract":"Article represents the results of main scientific researches in pancreatology conducted in 2016–2017. There are stated achievements of leading pancreatologists of Europe regarding study of etiology, pathogenesis, diagnostics and treatment of pancreatitis and tumors of the pancreas.","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126695664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical observation of thinning of psychogenic genesis after colectomy","authors":"N. Gubergrits, K. Y. Linevskaya, K. Voronin","doi":"10.33149/VKP.2018.03.10","DOIUrl":"https://doi.org/10.33149/VKP.2018.03.10","url":null,"abstract":"The article presents differential-diagnostic approaches based on the example of clinical observation of severe thinning, clinical features, diagnostics, treatment and prognosis for anorexia nervosa.","PeriodicalId":124329,"journal":{"name":"Bulletin of the Club of Pancreatologists","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125393977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}