Frontiers in Behavioral Neuroscience最新文献

{"title":"Individual corticosterone response to intermittent swim stress predicts a shift in economic demand for ethanol from pre-stress to post-stress in male rats.","authors":"Christopher L Robison, Victoria Madore, Nicole Cova, Robert C Drugan, Sergios Charntikov","doi":"10.3389/fnbeh.2024.1418544","DOIUrl":"10.3389/fnbeh.2024.1418544","url":null,"abstract":"<p><p>This study investigated the relationship between stress exposure and subsequent ethanol use, focusing on individual differences among male rats. We combined operant self-administration with behavioral economics to assess how intermittent swim stress affects ethanol consumption. This approach allowed for a nuanced analysis of the transition from regular ethanol intake to stress-induced escalation in economic demand. Results showed a consistent rise in ethanol demand post-stress among subjects, irrespective of exposure to actual swim stress or a sham procedure. This increase may result from a two-week abstinence or an inherent rise in demand over time. Significantly, we identified a direct link between post-stress corticosterone levels and the demand for ethanol, considering baseline levels. This correlation was particularly pronounced when examining the shifts in both corticosterone levels and demand for ethanol post-stress. However, neither post-stress corticosterone levels nor their change over time correlated significantly with changes in ethanol demand following a forced swim test that was administered 24 h after the intermittent swim stress test. This suggests potential context-specific or stressor-specific effects. Importantly, pre-stress ethanol demand did not significantly predict the corticosterone response to stress, indicating that high ethanol-demand rats do not inherently exhibit heightened stress sensitivity. Our research brings to light the complex interplay between stress and ethanol consumption, highlighting the critical role of individual differences in this relationship. This research introduces a nuanced perspective, underscoring the need for future studies in the realm of stress and substance use to give greater consideration to individual variability.</p>","PeriodicalId":12368,"journal":{"name":"Frontiers in Behavioral Neuroscience","volume":"18 ","pages":"1418544"},"PeriodicalIF":2.6,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11349677/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142105986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Cortico-hippocampal interactions during learning and memory.","authors":"Travis P Todd, Christian Bravo-Rivera, Karyn M Frick, Sharon C Furtak","doi":"10.3389/fnbeh.2024.1454782","DOIUrl":"10.3389/fnbeh.2024.1454782","url":null,"abstract":"","PeriodicalId":12368,"journal":{"name":"Frontiers in Behavioral Neuroscience","volume":"18 ","pages":"1454782"},"PeriodicalIF":2.6,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11347408/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142079885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurocognitive mechanisms of emotional interference in native and foreign languages: evidence from proficient bilinguals","authors":"Nicola Del Maschio, Simone Sulpizio, Camilla Bellini, Gianpaolo Del Mauro, Matteo Giannachi, Duygu Buga, Davide Fedeli, Daniela Perani, Jubin Abutalebi","doi":"10.3389/fnbeh.2024.1392005","DOIUrl":"https://doi.org/10.3389/fnbeh.2024.1392005","url":null,"abstract":"Currently available data show mixed results as to whether the processing of emotional information has the same characteristics in the native (L1) as in the second language (L2) of bilinguals. We conducted a functional magnetic resonance imaging (fMRI) experiment to shed light on the neurocognitive mechanisms underlying bilinguals’ emotional processing in L1 and L2 during an emotional interference task (i.e., the Emotional Stroop Task – EST). Our sample comprised proficient Italian-English bilinguals who learned their L2 during childhood mainly in instructional rather than immersive contexts. In spite of no detectable behavioural effects, we found stronger brain activations for L1 versus L2 emotional words in sectors of the posteromedial cortex involved in attention modulation, episodic memory, and affective processing. While fMRI findings are consistent with the hypothesis of a stronger emotional resonance when processing words in a native language, our overall pattern of results points to the different sensitivity of behavioural and hemodynamic responses to emotional information in the two languages of bilingual speakers.","PeriodicalId":12368,"journal":{"name":"Frontiers in Behavioral Neuroscience","volume":"41 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141938972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Pediatric autoimmune neuropsychiatric syndrome.","authors":"Natashia Bottoms, Sydney Rice, Aravindhan Veerapandiyan","doi":"10.3389/fnbeh.2024.1467469","DOIUrl":"10.3389/fnbeh.2024.1467469","url":null,"abstract":"","PeriodicalId":12368,"journal":{"name":"Frontiers in Behavioral Neuroscience","volume":"18 ","pages":"1467469"},"PeriodicalIF":2.6,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11334474/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142008571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Preclinical research in neurodegenerative diseases: biochemical, pharmacological, and behavioral bases.","authors":"Eduardo Rivadeneyra-Domínguez, Juan Francisco Rodríguez-Landa","doi":"10.3389/fnbeh.2024.1448790","DOIUrl":"10.3389/fnbeh.2024.1448790","url":null,"abstract":"","PeriodicalId":12368,"journal":{"name":"Frontiers in Behavioral Neuroscience","volume":"18 ","pages":"1448790"},"PeriodicalIF":2.6,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11330869/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142004002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adaptation of the inferior temporal neurons and efficient visual processing","authors":"Yukako Yamane","doi":"10.3389/fnbeh.2024.1398874","DOIUrl":"https://doi.org/10.3389/fnbeh.2024.1398874","url":null,"abstract":"Numerous studies examining the responses of individual neurons in the inferior temporal (IT) cortex have revealed their characteristics such as two-dimensional or three-dimensional shape tuning, objects, or category selectivity. While these basic selectivities have been studied assuming that their response to stimuli is relatively stable, physiological experiments have revealed that the responsiveness of IT neurons also depends on visual experience. The activity changes of IT neurons occur over various time ranges; among these, repetition suppression (RS), in particular, is robustly observed in IT neurons without any behavioral or task constraints. I observed a similar phenomenon in the ventral visual neurons in macaque monkeys while they engaged in free viewing and actively fixated on one consistent object multiple times. This observation indicates that the phenomenon also occurs in natural situations during which the subject actively views stimuli without forced fixation, suggesting that this phenomenon is an everyday occurrence and widespread across regions of the visual system, making it a default process for visual neurons. Such short-term activity modulation may be a key to understanding the visual system; however, the circuit mechanism and the biological significance of RS remain unclear. Thus, in this review, I summarize the observed modulation types in IT neurons and the known properties of RS. Subsequently, I discuss adaptation in vision, including concepts such as efficient and predictive coding, as well as the relationship between adaptation and psychophysical aftereffects. Finally, I discuss some conceptual implications of this phenomenon as well as the circuit mechanisms and the models that may explain adaptation as a fundamental aspect of visual processing.","PeriodicalId":12368,"journal":{"name":"Frontiers in Behavioral Neuroscience","volume":"62 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141771053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phospholipid supplementation inhibits male and female odor discrimination in mice","authors":"Maryana Morozova, Jelizaveta Andrejeva, Olga Snytnikova, Lidiya Boldyreva, Yuri Tsentalovich, Elena Kozhevnikova","doi":"10.3389/fnbeh.2024.1397284","DOIUrl":"https://doi.org/10.3389/fnbeh.2024.1397284","url":null,"abstract":"Dietary phospholipids (PLs) are promising supplements that are commonly found as natural food ingredients and emulsifier additives. The present study aimed to evaluate the effect of major PLs found in food supplements on social behavior in mice. In this study, the effect of short-term high dietary PL content was studied in terms of social odor discrimination and social interactions with male and female intruders in male mice. We used odor discrimination and habituation tests to demonstrate that PL-fed male mice tend to lose preference toward female odor and fail to discriminate against socially significant scents. At the same time, test animals recognize non-social odors. We also found that PL affected the social behavior of the test males, who tend to behave indiscriminately toward male and female intruders during direct contact. Brain metabolomic profiling revealed no major changes in the intermediary metabolism or neurotransmitter biosynthesis. At the same time, intranasal PL application resembled the effects of dietary supplementation. These data suggest that certain PL might suppress pheromone perception in the olfactory system and affect the sense of socially important odor cues.","PeriodicalId":12368,"journal":{"name":"Frontiers in Behavioral Neuroscience","volume":"24 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141770984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights into conscious cognitive information processing","authors":"Ekrem Dere","doi":"10.3389/fnbeh.2024.1443161","DOIUrl":"https://doi.org/10.3389/fnbeh.2024.1443161","url":null,"abstract":"For over a century, the neuro- and pathophysiological, behavioral, and cognitive correlates of consciousness have been an active field of theoretical considerations and empirical research in a wide range of modern disciplines. Conscious cognitive processing of information cannot be observed directly, but might be inferred from step-like discontinuities in learning performance or sudden insight-based improvements in problem solving behavior. It is assumed that a sudden step of knowledge associated with insight requires a creative reorganization of mental representations of task- or problem-relevant information and the restructuration of the task, respectively problem to overcome an cognitive dead-end or impasse. Discontinuities in learning performance or problem solving after an insight event can be used as time-tags to capture the time window in which conscious cognitive information processing must have taken place. According to the platform theory of conscious cognitive information processing, the reorganization and restructuration processes, require the maintenance of task- or problem-relevant information in working memory for the operation of executive functions on these mental representations. Electrophysiological evidence suggests that the reorganization and restructuration processes in working memory, that precede insight-based problem solutions are accompanied by an increase in the power of gamma oscillations in cortical areas including the prefrontal cortex. Empirical evidence and theoretical assumptions argue for an involvement of gap junction channels and connexin hemichannels in cortical gamma-oscillations and working memory processes. Discontinuities in learning or problem solving performance might be used as time-tags to investigate the implication of gap junction channels and hemichannels in conscious cognitive processing.","PeriodicalId":12368,"journal":{"name":"Frontiers in Behavioral Neuroscience","volume":"32 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141770985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frontiers | Cognitive mechanisms of learning in sequential decision-making under uncertainty: an experimental and theoretical approach","authors":"Gloria Cecchini, Michael DePass, Emre Baspinar, Marta Andujar, Surabhi Ramawat, Pierpaolo Pani, Stefano Ferraina, Alain Destexhe, Rubén Moreno-Bote, Ignasi Cos","doi":"10.3389/fnbeh.2024.1399394","DOIUrl":"https://doi.org/10.3389/fnbeh.2024.1399394","url":null,"abstract":"Learning to make adaptive decisions involves making choices, assessing their consequence, and leveraging this assessment to attain higher rewarding states. Despite vast literature on value-based decision-making, relatively little is known about the cognitive processes underlying decisions in highly uncertain contexts. Real world decisions are rarely accompanied by immediate feedback, explicit rewards, or complete knowledge of the environment. Being able to make informed decisions in such contexts requires significant knowledge about the environment, which can only be gained via exploration. Here we aim at understanding and formalizing the brain mechanisms underlying these processes. To this end, we first designed and performed an experimental task. Human participants had to learn to maximize reward while making sequences of decisions with only basic knowledge of the environment, and in the absence of explicit performance cues. Participants had to rely on their own internal assessment of performance to reveal a covert relationship between their choices and their subsequent consequences to find a strategy leading to the highest cumulative reward. Our results show that the participants’ reaction times were longer whenever the decision involved a future consequence, suggesting greater introspection whenever a delayed value had to be considered. The learning time varied significantly across participants. Second, we formalized the neurocognitive processes underlying decision-making within this task, combining mean-field representations of competing neural populations with a reinforcement learning mechanism. This model provided a plausible characterization of the brain dynamics underlying these processes, and reproduced each aspect of the participants’ behavior, from their reaction times and choices to their learning rates. In summary, both the experimental results and the model provide a principled explanation to how delayed value may be computed and incorporated into the neural dynamics of decision-making, and to how learning occurs in these uncertain scenarios.","PeriodicalId":12368,"journal":{"name":"Frontiers in Behavioral Neuroscience","volume":"133 1","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141938973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum: Plasticity of carbohydrate transport at the blood-brain barrier.","authors":"Ellen McMullen, Astrid Weiler, Holger M Becker, Stefanie Schirmeier","doi":"10.3389/fnbeh.2024.1443912","DOIUrl":"https://doi.org/10.3389/fnbeh.2024.1443912","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.3389/fnbeh.2020.612430.].</p>","PeriodicalId":12368,"journal":{"name":"Frontiers in Behavioral Neuroscience","volume":"18 ","pages":"1443912"},"PeriodicalIF":2.6,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11294888/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141888957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}