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Expert Review of Vaccines最新文献

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Influenza burden averted with a cell-based quadrivalent seasonal influenza vaccine compared with egg-based quadrivalent seasonal influenza vaccine. 细胞型四价季节性流感疫苗与鸡蛋型四价季节性流感疫苗相比可避免的流感负担。
IF 6.2 3区 医学
Expert Review of Vaccines Pub Date : 2024-01-01 Epub Date: 2024-03-18 DOI: 10.1080/14760584.2024.2330643
Ian McGovern, Alexandra Taylor, Aditya Sardesai, Hector Toro-Diaz, Mendel Haag
{"title":"Influenza burden averted with a cell-based quadrivalent seasonal influenza vaccine compared with egg-based quadrivalent seasonal influenza vaccine.","authors":"Ian McGovern, Alexandra Taylor, Aditya Sardesai, Hector Toro-Diaz, Mendel Haag","doi":"10.1080/14760584.2024.2330643","DOIUrl":"10.1080/14760584.2024.2330643","url":null,"abstract":"<p><strong>Background: </strong>Cell-based quadrivalent inactivated influenza vaccines (IIV4c) avoid egg-adaptive mutations found in egg-based production, improving vaccine effectiveness (VE). Studies demonstrate improved VE for IIV4c relative to egg-based quadrivalent inactivated influenza vaccines (IIV4).</p><p><strong>Research design and methods: </strong>We built on a static compartmental model developed by the CDC to estimate the influenza burden in persons 0-64 years that would be additionally averted by vaccination with IIV4c vs. IIV4. Model inputs were based on published data from 2017-2018, 2018-2019, and 2019-2020 Northern Hemisphere influenza seasons for the US.</p><p><strong>Results: </strong>Over 3 influenza seasons, relative to IIV4, IIV4c would avert 31-39% more symptomatic cases, 29-40% more outpatient visits, 29-38% more hospitalizations and ICU admissions, and 34-49% more deaths vs. IIV4. In a deterministic sensitivity analysis, the main drivers were the relative VE of IIV4c vs. IIV4 in the 2017-2018 season and influenza burden estimates for the 2018-2019 and 2019-2020 seasons. Probabilistic sensitivity analysis showed that the interquartile range of symptomatic cases was ± 13% of baseline in 2017-2018, ±8% in 2018-2019, and ± 7% in 2019-2020.</p><p><strong>Conclusions: </strong>IIV4c prevented significantly more symptomatic cases, outpatient visits, hospitalizations, and deaths than IIV4 in persons aged 0-64 years over 3 influenza seasons.</p>","PeriodicalId":12326,"journal":{"name":"Expert Review of Vaccines","volume":"23 1","pages":"371-379"},"PeriodicalIF":6.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140143120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adaptive immune response to bordetella pertussis during vaccination and infection: emerging perspectives and unanswered questions. 疫苗接种和感染期间对百日咳杆菌的适应性免疫反应：新观点和未解之谜。
IF 5.5 3区 医学
Expert Review of Vaccines Pub Date : 2024-01-01 Epub Date: 2024-07-24 DOI: 10.1080/14760584.2024.2383745
A-Reum Kim, Alessandro Sette, Ricardo da Silva Antunes
{"title":"Adaptive immune response to bordetella pertussis during vaccination and infection: emerging perspectives and unanswered questions.","authors":"A-Reum Kim, Alessandro Sette, Ricardo da Silva Antunes","doi":"10.1080/14760584.2024.2383745","DOIUrl":"10.1080/14760584.2024.2383745","url":null,"abstract":"<p><strong>Introduction: </strong>Whooping cough, also known as pertussis, remains a significant challenge as a vaccine-preventable disease worldwide. Since the switch from the whole-cell Pertussis (wP) vaccine to the acellular Pertussis vaccine (aP), cases of whooping cough have increased in countries using the aP vaccine. Understanding the immune system's response to pertussis vaccines and infection is crucial for improving current vaccine efficacy.</p><p><strong>Areas covered: </strong>This review of the literature using PubMed records offers an overview of the qualitative differences in antibody and T cell responses to B. pertussis (BP) in vaccination and infection, and their potential association with decreased efficacy of the aP vaccine in preventing infection and subclinical colonization. We further discuss how asymptomatic infections and carriage are widespread among vaccinated human populations, and explore methodologies that can be employed for their detection, to better understand their impact on adaptive immune responses and identify key features necessary for protection against the disease.</p><p><strong>Expert opinion: </strong>An underappreciated human BP reservoir, stemming from the decreased capacity of the aP vaccine to prevent subclinical infection, offers an alternative explanation for the increased incidence of clinical disease and recurrent outbreaks.</p>","PeriodicalId":12326,"journal":{"name":"Expert Review of Vaccines","volume":" ","pages":"705-714"},"PeriodicalIF":5.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11306532/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141733848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunogenicity and safety of ebolavirus vaccines in healthy adults: a systematic review and meta-analysis of randomized controlled trials 健康成人接种埃博拉病毒疫苗的免疫原性和安全性：随机对照试验的系统回顾和荟萃分析
IF 6.2 3区 医学
Expert Review of Vaccines Pub Date : 2023-12-19 DOI: 10.1080/14760584.2023.2296937
Mingsan Miao, Juntao Yin, Liang Zhang, Chaoyang Wang, Changjiang Qin
{"title":"Immunogenicity and safety of ebolavirus vaccines in healthy adults: a systematic review and meta-analysis of randomized controlled trials","authors":"Mingsan Miao, Juntao Yin, Liang Zhang, Chaoyang Wang, Changjiang Qin","doi":"10.1080/14760584.2023.2296937","DOIUrl":"https://doi.org/10.1080/14760584.2023.2296937","url":null,"abstract":"This review aimed to systematically evaluate the immunogenicity and safety of the candidate ebolavirus vaccine (EVV).We searched five databases for randomized controlled trials (RCTs) evaluating th...","PeriodicalId":12326,"journal":{"name":"Expert Review of Vaccines","volume":"45 1","pages":""},"PeriodicalIF":6.2,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138743047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PCV15, a pneumococcal conjugate vaccine, for the prevention of invasive pneumococcal disease in infants and children 用于预防婴幼儿侵袭性肺炎球菌疾病的肺炎球菌结合疫苗 PCV15
IF 6.2 3区 医学
Expert Review of Vaccines Pub Date : 2023-12-19 DOI: 10.1080/14760584.2023.2294153
Timothy J Chapman, Liset Olarte, Ghassan Dbaibo, Avril Melissa Houston, Gretchen Tamms, Robert Lupinacci, Kristen Feemster, Ulrike K Buchwald, Natalie Banniettis
{"title":"PCV15, a pneumococcal conjugate vaccine, for the prevention of invasive pneumococcal disease in infants and children","authors":"Timothy J Chapman, Liset Olarte, Ghassan Dbaibo, Avril Melissa Houston, Gretchen Tamms, Robert Lupinacci, Kristen Feemster, Ulrike K Buchwald, Natalie Banniettis","doi":"10.1080/14760584.2023.2294153","DOIUrl":"https://doi.org/10.1080/14760584.2023.2294153","url":null,"abstract":"Streptococcus pneumoniae is a causative agent of pneumonia and acute otitis media (AOM), as well as invasive diseases such as meningitis and bacteremia. PCV15 (V114) is a new 15-valent pneumococcal...","PeriodicalId":12326,"journal":{"name":"Expert Review of Vaccines","volume":"132 1","pages":""},"PeriodicalIF":6.2,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138743044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plasmodium falciparum merozoite surface protein 1 as asexual blood stage malaria vaccine candidate 恶性疟原虫裂殖体表面蛋白 1 作为候选无性血型疟疾疫苗
IF 6.2 3区 医学
Expert Review of Vaccines Pub Date : 2023-12-15 DOI: 10.1080/14760584.2023.2295430
Richard Thomson-Luque, Thomas C Stabler, Kristin Fürle, Joana C Silva, Claudia Daubenberger
{"title":"Plasmodium falciparum merozoite surface protein 1 as asexual blood stage malaria vaccine candidate","authors":"Richard Thomson-Luque, Thomas C Stabler, Kristin Fürle, Joana C Silva, Claudia Daubenberger","doi":"10.1080/14760584.2023.2295430","DOIUrl":"https://doi.org/10.1080/14760584.2023.2295430","url":null,"abstract":"Malaria represents a tremendous public health challenge in tropical and sub-tropical regions, and currently deployed control strategies are likely insufficient to drive elimination of malaria. Deve...","PeriodicalId":12326,"journal":{"name":"Expert Review of Vaccines","volume":"41 1","pages":""},"PeriodicalIF":6.2,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138684349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predicted serotype-specific effectiveness of pneumococcal conjugate vaccines V114 and PCV20 against invasive pneumococcal disease in children 肺炎球菌结合疫苗 V114 和 PCV20 对儿童侵袭性肺炎球菌疾病的血清型特异性效果预测
IF 6.2 3区 医学
Expert Review of Vaccines Pub Date : 2023-12-14 DOI: 10.1080/14760584.2023.2292773
Josiah Ryman, Jeffrey R. Sachs, Ka Lai Yee, Natalie Banniettis, Jessica Weaver, Thomas Weiss
{"title":"Predicted serotype-specific effectiveness of pneumococcal conjugate vaccines V114 and PCV20 against invasive pneumococcal disease in children","authors":"Josiah Ryman, Jeffrey R. Sachs, Ka Lai Yee, Natalie Banniettis, Jessica Weaver, Thomas Weiss","doi":"10.1080/14760584.2023.2292773","DOIUrl":"https://doi.org/10.1080/14760584.2023.2292773","url":null,"abstract":"Next-generation, higher-valency pneumococcal conjugate vaccines (PCVs), 15-valent PCV V114 and 20-valent PCV (PCV20), have been assessed by comparing their immune responses across serotypes shared ...","PeriodicalId":12326,"journal":{"name":"Expert Review of Vaccines","volume":"6 1","pages":""},"PeriodicalIF":6.2,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138628051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pre-erythrocytic malaria vaccines: RTS,S, R21, and beyond 红细胞前疟疾疫苗：RTS、S、R21 及其他
IF 6.2 3区 医学
Expert Review of Vaccines Pub Date : 2023-12-14 DOI: 10.1080/14760584.2023.2292204
Elizabeth Adrianne Hammershaimb, Andrea A. Berry
{"title":"Pre-erythrocytic malaria vaccines: RTS,S, R21, and beyond","authors":"Elizabeth Adrianne Hammershaimb, Andrea A. Berry","doi":"10.1080/14760584.2023.2292204","DOIUrl":"https://doi.org/10.1080/14760584.2023.2292204","url":null,"abstract":"Published in Expert Review of Vaccines (Vol. 23, No. 1, 2024)","PeriodicalId":12326,"journal":{"name":"Expert Review of Vaccines","volume":"38 1","pages":""},"PeriodicalIF":6.2,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138628048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modelling the population-level benefits and cost-effectiveness of cell-based quadrivalent influenza vaccine for children and adolescents aged 6 months to 17 years in the US 为美国 6 个月至 17 岁儿童和青少年接种细胞型四价流感疫苗的人群效益和成本效益建模
IF 6.2 3区 医学
Expert Review of Vaccines Pub Date : 2023-12-14 DOI: 10.1080/14760584.2023.2295014
Stephen I. Pelton, Joaquin F. Mould-Quevedo, Van Hung Nguyen
{"title":"Modelling the population-level benefits and cost-effectiveness of cell-based quadrivalent influenza vaccine for children and adolescents aged 6 months to 17 years in the US","authors":"Stephen I. Pelton, Joaquin F. Mould-Quevedo, Van Hung Nguyen","doi":"10.1080/14760584.2023.2295014","DOIUrl":"https://doi.org/10.1080/14760584.2023.2295014","url":null,"abstract":"Cell-based quadrivalent influenza vaccines (QIVc) can increase effectiveness against seasonal influenza by avoiding mismatch from egg adaption of vaccine viruses. This study evaluates the populatio...","PeriodicalId":12326,"journal":{"name":"Expert Review of Vaccines","volume":"18 1","pages":""},"PeriodicalIF":6.2,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138627976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influvac Tetra: clinical experience on safety, efficacy, and immunogenicity Influvac Tetra：安全性、有效性和免疫原性方面的临床经验
IF 6.2 3区 医学
Expert Review of Vaccines Pub Date : 2023-12-13 DOI: 10.1080/14760584.2023.2293241
Laura Colombo, Sanjay Hadigal, Jos Nauta, Alona Kondratenko, Jutta Rogoll, Serge Van de Witte
{"title":"Influvac Tetra: clinical experience on safety, efficacy, and immunogenicity","authors":"Laura Colombo, Sanjay Hadigal, Jos Nauta, Alona Kondratenko, Jutta Rogoll, Serge Van de Witte","doi":"10.1080/14760584.2023.2293241","DOIUrl":"https://doi.org/10.1080/14760584.2023.2293241","url":null,"abstract":"This paper summarizes the safety and immunogenicity data of Influvac Tetra across all age groups starting from 6 months of age, obtained during its clinical development program.The article covers t...","PeriodicalId":12326,"journal":{"name":"Expert Review of Vaccines","volume":"63 1","pages":""},"PeriodicalIF":6.2,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138628280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real world evidence for public health decision-making on vaccination policies: perspectives from an expert roundtable 疫苗接种政策公共卫生决策的现实证据：专家圆桌会议的观点
IF 6.2 3区 医学
Expert Review of Vaccines Pub Date : 2023-12-12 DOI: 10.1080/14760584.2023.2290194
Chiara de Waure, Barbara C. Gärtner, Pier Luigi Lopalco, Joan Puig-Barbera, Jonathan S. Nguyen-Van-Tam
{"title":"Real world evidence for public health decision-making on vaccination policies: perspectives from an expert roundtable","authors":"Chiara de Waure, Barbara C. Gärtner, Pier Luigi Lopalco, Joan Puig-Barbera, Jonathan S. Nguyen-Van-Tam","doi":"10.1080/14760584.2023.2290194","DOIUrl":"https://doi.org/10.1080/14760584.2023.2290194","url":null,"abstract":"Influenza causes significant morbidity and mortality, but influenza vaccine uptake remains below most countries’ targets. Vaccine policy recommendations vary, as do procedures for reviewing and app...","PeriodicalId":12326,"journal":{"name":"Expert Review of Vaccines","volume":"15 1","pages":""},"PeriodicalIF":6.2,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138576084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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