Fiziolohichnyi zhurnal最新文献_第2页

COMPARISON OF SPECTROSCOPIC PROPERTIES OF INTRAOCULAR FLUID IN PATIENTS WITH CATARACT AND PRIMARY OPEN-ANGLE GLAUCOMA. 白内障与原发性开角型青光眼的眼内液光谱特性比较。

Fiziolohichnyi zhurnal Pub Date : 2016-01-01 DOI: 10.15407/FZ62.05.062

S. Kolotilov, V. Melnyk, A. Lytvynenko, S. O. Sotnik, O. Hurzhii

{"title":"COMPARISON OF SPECTROSCOPIC PROPERTIES OF INTRAOCULAR FLUID IN PATIENTS WITH CATARACT AND PRIMARY OPEN-ANGLE GLAUCOMA.","authors":"S. Kolotilov, V. Melnyk, A. Lytvynenko, S. O. Sotnik, O. Hurzhii","doi":"10.15407/FZ62.05.062","DOIUrl":"https://doi.org/10.15407/FZ62.05.062","url":null,"abstract":"This paper presents a comparison ofspectroscopic properties of aqueous humour in patients with cataract (60 patients, 60 eyes) and combination of cataract and primary open angle glaucoma (POAG, 36 patients, 36 eyes). The samples of aqueous humour were collected during the surgery. Both groups of patients were treated with different types of local drug antihypertensive therapy with different multiplicity and duration of instillation during the preoperative period. The absorption spectrum of aqueous humour were measured in the wavelength range 190-1100 nm. There were two absorption bands with maximums at 202 and 267 nm in the absorption spectrum (2nd maximum of some samples was shifted to larger wavelengths). The mean absorbance of aqueous humour at 202 nm in patients without POAG was significantly lower than in patients with POAG. This difference could be explained with accumulation of metabolites in aqueous humour of patients with POAG, which in turn may be caused by deceleration of aqueous humour flow in patients with POAG. Meanwhile, there were no statistically significant differences of mean absorbance of aqueous humour at 267 nm between the patients of both groups.","PeriodicalId":12306,"journal":{"name":"Fiziolohichnyi zhurnal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74705435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

STATUS OF GLUTATHIONE-DEPENDENT LINK OF BLOOD ANTIOXIDANT SYSTEM UNDER APPLICATION OF FENUGREEK SEED POWDER IN ANIMALS WITH EXPERIMENTAL OBESITY. 胡芦巴籽粉对实验性肥胖动物血液抗氧化系统谷胱甘肽依赖环节的影响。

Fiziolohichnyi zhurnal Pub Date : 2016-01-01 DOI: 10.15407/FZ62.05.069

V. Konopelnyuk, L. Kot, T. Koval, T. D. Khilko, I. Yakubtsova, T. Preobrazhenska, L. Ostapchenko

引用次数: 0

[ALLELIC VARIANT FREQUENCY OF PROMOTER (G(-47)-->A) γ-CRYSTALLIN GENE AFFECTS THE LEVEL OF ITS EXPRESSION IN PLATELETS]. [启动子(g(-47)—> a) γ-晶体蛋白基因等位基因变异频率影响其在血小板中的表达水平]。

Fiziolohichnyi zhurnal Pub Date : 2015-01-01 DOI: 10.15407/FZ61.04.030

S. Rykov, Y. Y. Byts, S. Goncharov, V. Dosenko

引用次数: 1

[FUNCTIONING PROTEASES IN THE ESOPHAGUS MUCOSA AFTER CHEMICAL BURNS]. [化学烧伤后食管黏膜功能蛋白酶]。

Fiziolohichnyi zhurnal Pub Date : 2015-01-01 DOI: 10.15407/FZ61.05.071

T. Ishchuk, O. Savchuk, Y. Raetska, V. Vereschaka, L. Ostapchenko

引用次数: 2

[HYDROGEN SULFIDE DONOR, NAHS, RECOVERS CONSTITUTIVE NO SYNTHESIS AND ENDOTHELIUM-DEPENDENT RELAXATION OF ISOLATED AORTA IN OLD RATS]. [硫化氢供体，nahs，恢复老年大鼠离体主动脉组成性一氧化氮合成和内皮依赖性松弛]。

Fiziolohichnyi zhurnal Pub Date : 2015-01-01 DOI: 10.15407/FZ61.06.003

K. Drachuk, A. Kotsjuruba, V. Sagach

引用次数: 11

[GLYCINE RECEPTOR: MOLECULAR ORGANIZATION AND PATHOLOGY]. [甘氨酸受体:分子组织与病理]。

Fiziolohichnyi zhurnal Pub Date : 2015-01-01 DOI: 10.1615/INTJPHYSPATHOPHYS.V7.I4.80

G. Maleeva, P. Bregestovski

引用次数: 1

Expression of aryl hydrocarbon receptor and ATG16L1 protein in experimental oxazolone-induced colitis in rats. 实验性恶唑酮诱导大鼠结肠炎中芳烃受体和ATG16L1蛋白的表达。

Fiziolohichnyi zhurnal Pub Date : 2015-01-01 DOI: 10.15407/FZ61.05.057

Zherebiatiev As, Kamyshny Am

引用次数: 1

[BRAIN FOCAL ISCHEMIA-REPERFUSION CAUSES A DECREASED RESISTANCE OF ERYTHROCYTES FROM VENOUS BLOOD TO ACID HEMOLYSIS, WHICH IS PREVENTED BY ECDYSTERONE]. [脑局灶性缺血-再灌注引起静脉血红细胞对酸性溶血的抵抗力降低，蜕皮酮可预防]。

Fiziolohichnyi zhurnal Pub Date : 2015-01-01 DOI: 10.15407/FZ61.05.003

A. Kotsuruba, R. Sharipov, B. S. Kopyak, V. Sagach

{"title":"[BRAIN FOCAL ISCHEMIA-REPERFUSION CAUSES A DECREASED RESISTANCE OF ERYTHROCYTES FROM VENOUS BLOOD TO ACID HEMOLYSIS, WHICH IS PREVENTED BY ECDYSTERONE].","authors":"A. Kotsuruba, R. Sharipov, B. S. Kopyak, V. Sagach","doi":"10.15407/FZ61.05.003","DOIUrl":"https://doi.org/10.15407/FZ61.05.003","url":null,"abstract":"We investigated the resistance of erythrocytes from rat brain venous blood to acid hemolysis in the dynamics of brain ischemic period (15, 30, 45 and 60 min), as well as in the early (5 min) and distant (24h) period of brain reperfusion. Brain ischemia-reperfusion was made in rats that received ecdysterone (standartized extract of Serratula coronata) within 18 days (per os, 1 mg/kg). Analysis of the kinetic curves of acid hemolysis showed a pronounced (60 times, from 1.45 to 85.85% at 60 min of brain ischemia and at 5 min of brain reperfusion, respectively) increase of unstable erythrocytes that hemolyzed easily (< 2.5 min). In the preconditioned rats, this increase was only 8-fold. During the period of brain ischemia, with a maximum at 15th minute, in the venous blood from brain the diene conjugates (DK) pools increased from 2.40 to 9.48 ng/mg protein and LTC4 pools increased from 1.49 to 5.98 pmol/mg protein. Even more pools of DC and LTC4 were increased at 5th min of brain reperfusion. In animals received ecdysterone, during ischemia and early reperfusion period, both pools of DC and LTC4 in venous blood were lower than that in the controls. The latter implies a possible antiradical mechanism of the protective effect of ecdysterone.","PeriodicalId":12306,"journal":{"name":"Fiziolohichnyi zhurnal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82378256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

[EFFECT OF PEPTIDE SEMAX ON SYNAPTIC ACTIVITY AND SHORT-TERM PLASTICITY OF GLUTAMATERGIC SYNAPSES OF CO-CULTURED DORSAL ROOT GANGLION AND DORSAL HORN NEURONS]. [肽semax对共培养背根神经节和背角神经元谷氨酸能突触活性和短期可塑性的影响]。

Fiziolohichnyi zhurnal Pub Date : 2015-01-01 DOI: 10.15407/FZ61.04.048

M. Shypshyna, N. Veselovsky, N. Myasoedov, S. Shram, S. Fedulova

{"title":"[EFFECT OF PEPTIDE SEMAX ON SYNAPTIC ACTIVITY AND SHORT-TERM PLASTICITY OF GLUTAMATERGIC SYNAPSES OF CO-CULTURED DORSAL ROOT GANGLION AND DORSAL HORN NEURONS].","authors":"M. Shypshyna, N. Veselovsky, N. Myasoedov, S. Shram, S. Fedulova","doi":"10.15407/FZ61.04.048","DOIUrl":"https://doi.org/10.15407/FZ61.04.048","url":null,"abstract":"The influence of long-term culturing (12 days in vitro) of dorsal root ganglion (DRG) and dorsal horn (DH) neurons with peptide Semax on the level of synaptic activity at co-cultures, as well as short-term plasticity in sensory synapses were studied. It has been shown that neuronal culturing with peptide at concentrations of 10 and 100 µM led to increasing the frequency of spontaneous glutamatergic postsynaptic currents in DH neurons to 71.7 ± 1.8% and 93.9 ± 3.1% (n = 6; P < 0.001); Semax has a not significant effect on the amplitude and frequency of miniature glutamatergic currents, but causes an increase of the amplitudes of spontaneous postsynaptic currents, as well as elevates the quantum content. The data show the increase of multivesicular glutamate release efficiency in neural networks of co-cultures following incubation with the peptide. Also Semax (10 and 100 µM) induces changes of the basic parameters of short-term plasticity in sensory synapses: (1) increasing the paired-pulse ratio from 0.53 ± 0.028 (n = 8) to 0.91 ± 0.072 (n = 6, P < 0.01) and 0.95 ± 0.026 (n = 7; P < 0.001); (2) reducing the ratio of the coefficients of variation (CV2/ CV1) from 1.49 ± 0.11 (n = 8) to 1.02 ± 0.09 (n = 6; P < 0.05) and 1.11 ± 0.13 (n = 7; P < 0.0) respectively. The results indicate a stimulating effect of Semax on the activity of glutamatergic synapses in neural networks of co-cultures, as well as the ability of the peptide to effectively modulate the short-term plasticity in sensory synapses.","PeriodicalId":12306,"journal":{"name":"Fiziolohichnyi zhurnal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86633896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

[MORPHOFUNCTIONAL STATE OF THE THYROID GLAND AFTER EXPOSURE TO MELATONIN]. [接触褪黑激素后甲状腺的形态功能状态]。

Fiziolohichnyi zhurnal Pub Date : 2015-01-01 DOI: 10.15407/FZ61.05.046

R. Yanko

{"title":"[MORPHOFUNCTIONAL STATE OF THE THYROID GLAND AFTER EXPOSURE TO MELATONIN].","authors":"R. Yanko","doi":"10.15407/FZ61.05.046","DOIUrl":"https://doi.org/10.15407/FZ61.05.046","url":null,"abstract":"Morphofunctional state of the thyroid gland (TG) of young rats after exposure of exogenous melatonin in the spring and autumn periods was investigated. Exogenous melatonin (Unipharm Inc., USA) was administered to experimental group of animals daily at a dose 5 mg/kg. The duration of the experiment was 28 days. It was shown an increase of the cross-section area of follicles by 31% and colloid by 30% (in spring), reduction of the area of follicle epithelium by 12% (in autumn), an increase in the follicle internal diameter and a decline in the thyroid epithelium height by 12% (in autumn) in TG of experimental groups rats. Also it was shown a decline of follicle-colloid index and growth of colloid accumulation index, reduction amount of interfollicular islets. The introduction of melatonin in the spring period brought down the amount of connecting tissue elements. Melatonin introduction in the autumn period reduced the thickness of connective tissue trabecules in TG. The introduction of melatonin in the spring period resulted in more substantial changes in the structure of TG, as compared to an autumn experiment. Thus, melatonin administered both in the spring and in the autumn periods reduces the functional activity and physiological regeneration of TG.","PeriodicalId":12306,"journal":{"name":"Fiziolohichnyi zhurnal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85620905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0