Experimental and Сlinical Urology最新文献

{"title":"Enchanсed recovery. Relevance, history, pathophysiology.","authors":"V. Vorobev, V. Beloborodov, A. Tukhiev","doi":"10.29188/2222-8543-2022-15-4-10-17","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-4-10-17","url":null,"abstract":"Introduction. The Enhanced Recovery Program (ERP), Fast Track surgery (FTS), and ERAS (enhanced recovery after surgery/rapid recovery after surgery programs) is a multimodal and multidisciplinary treatment strategy designed to reduce the duration of disability and improve the quality of medical care. This program includes preparation at the preoperative stage, the use of minimally invasive techniques for performing surgical intervention and active management of the postoperative period to reduce the duration of inpatient treatment, rehabilitation time and the fastest possible return of patients to normal life. One of the key factors for the success of the ERP is the introduction of multidisciplinary interaction at all stages of examination and treatment. The history of the development of enhanced recovery programs is briefly described, the relevance of the development and application of an optimized treatment strategy, the problems of integration and multidisciplinary are described. The review of the features of the pathophysiology of perioperative stress and practical conclusions justifying the development and application of elements of the enhanced recovery program are presented.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128701890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical treatment of inferior vena cava tumor thrombus.","authors":"uulu Z. Polotbek, A.A. Сhevina, V. Raguzina, V. A. Oganyan, I. Miroshkina, N. Karelskaya, Y. Stepanova, A. G. Kochetov, S. Sapelkin","doi":"10.29188/2222-8543-2022-15-4-18-31","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-4-18-31","url":null,"abstract":"Introduction. Venous invasion and tumor thrombus formation are rare, but life-threatening complications of renal cell carcinoma (RCC), especially in combination with metastases, are considered significant adverse prognostic factors. Aim. To systematize the existing knowledge and summarize the clinical experience of surgical treatment (open and robot-assisted surgery) of RCC with inferior vena cava (IVC) tumor thrombus. Materials and methods. A literature search in the period 2000-2022 was performed in core databases MEDLINE, Scopus, Clinicaltrials.gov, Google Scholar and Web of Science. The PICO framework (Population-Intervention-Comparison-Outcome) was used to develop a literature search strategy. The following keywords were used to search databases: «renal cell carcinoma», «venous invasion», «inferior vena cava tumor thrombus», «surgical treatment», «robot-assisted», «clinical outcomes». Results. A total of 65 publications were identified. Various classifications of tumor thrombus level are considered, their inferiority and superiority in terms of selecting optimal surgical treatment, both open or robot-assisted surgeries, are discussed. Independent predictors of severe perioperative complications are determined. Optimal surgical treatment of RCC with tumor thrombus is highlighted. Functional and oncological outcomes of patients with RCC with IVC tumor thrombus, who underwent open surgical intervention and robot-assisted ones, are presented. Conclusion. Open surgery in patients with RCC and IVC tumor thrombus above the hepatic veins is associated with prolonged surgery duration, higher intraoperative blood loss, and prolonged in-hospital stay. Prolonged in-hospital stay, the need for blood transfusion, metastasis, sarcomatoid differentiation, and Clavien-Dindo grade 3-5 postoperative complications are predictors of poor outcomes.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125481518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemangioma of the glans penis.","authors":"K.I. Pelikh, D. Filippov, S.A. Buraya, I. Kagantsov","doi":"10.29188/2222-8543-2022-15-4-155-159","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-4-155-159","url":null,"abstract":"Introduction. Hemangioma of the genitourinary system is not common, and accounts for about 2% of cases among all hemangiomas. Its localization on the scrotum and glans penis is the most rare and the incidence of this pathology is less than 1%. The available literature presents various approaches to the treatment of penile hemangioma: drugs that inhibit the growth of blood vessels and narrow existing blood vessels (propranolol), surgical excision, sclerotherapy using a neodymium laser, sclerotherapy using polidocanol are used. The aim of our work is to report a rare clinical case of hemangioma of the glans penis in a 17-year-old boy and the results of treatment of this pathology. Clinical case. The article presents a clinical case of treatment of a 17-year-old patient with hemangioma of the glans penis, whose treatment method was sclerotherapy with 2% polidocanol (Ethoxysclerol). A good cosmetic and functional result was obtained using a 3-fold injection of the drug. Discussion. An analysis of the world literature on the treatment of penile hemangioma showed that at present there is no single approach to the treatment of this pathology and that one of the promising methods is sclerotherapy using various sclerosants. Conclusions. Sclerotherapy of penile hemangioma using 2% polidocanol (Ethoxysclerol) has proven to be an effective, inexpensive and technically uncomplicated method of treatment and may be the method of choice in the treatment of this pathology in children.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125215057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abdominal cryptorchidism with background complete dissociation between the testis and the deferent duct simulating testicular regression syndrome.","authors":"V. Sizonov, A. Makarov, V. V. Vigera","doi":"10.29188/2222-8543-2022-15-4-150-154","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-4-150-154","url":null,"abstract":"Introduction. Complete separation of the deferent duct from the epididymis with the testicle in abdominal cryptorchidism cases is an extremely rare variation of abnormal development of genitals in boys. Available sources mention just 3 clinical cases similar to our observations. The unique anatomic details of the abnormality and extreme rarity of its exposure pave the way for a failure to reveal an intra-abdominal testis, and determine the need for particular attention during diagnostic laparoscopy. Materials and methods. Two patients with non-palpable left-sided cryptorchidism underwent a diagnostic laparoscopy, which revealed an intra-abdominal testis with epididymis on testicular vessels that was completely separated from the deferent duct. The difference between the described clinical cases was in the distance between the deep inguinal ring and the crossing of testicular vessels from the retroperitoneal location to the intraperitoneal position, which was approximately 3- 4 cm in the first patient and 4-5 mm in the second one. The second difference was in the \"closed\" deep inguinal ring found on the left side in the first case while the second patient had a patent processus vaginalis case. In both cases an incision was made in the left inguinal area, the inguinal canal was opened, and exploration thereof revealed blind-ended deferent ducts. The testicle in both cases was brought down through the inguinal canal and attached in the scrotum. Results. No complications occurred during the early postoperative care period, the check-up examination in 6 months following the surgery revealed no signs of testis atrophy or malposition in both patients. Conclusion. In diagnostic laparoscopy for abdominal cryptorchidism, it is important to consider the possibility of complete separation of the testicle and vas deferens. Detection of the deferent duct passing through the «closed» deep inguinal ring together with hypoplastic vessels does not rule out the chances for an ipsolateral intra-abdominal testis; therefore, a careful examination of the abdominal cavity along the embryological testicular migration path is necessary.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132470367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rational pharmacotherapy for metabolic risk factors for erectile dysfunction.","authors":"S. Krasnyak","doi":"10.29188/2222-8543-2022-15-4-86-94","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-4-86-94","url":null,"abstract":"Introduction. The process of erection occurs through the coordination of several pathways. Therefore, any negative conditions and risk factors will make worse the quality of erection and can cause erectile dysfunction (ED). One of these conditions is metabolic syndrome. Aim. To evaluate the data published over the past 20 years on the prevalence, causes and risk factors, as well as conservative therapy for erectile dysfunction. Materials and methods. The search results in scientific database PubMed for the queries «physiology of erection», «erectile dysfunction», «risk factors for erectile dysfunction», «treatment of erectile dysfunction». Found 574 materials, 60 articles have been selected for writing a review of. Results. The global prevalence of ED varies greatly, ranging from 3% to 76.5%. However, ED was associated with increasing age. Among the main risk factors for ED are arterial hypertension, obesity, hyperlipidemia and diabetes mellitus. Now, conservative therapy for ED is aimed at treating individual risk factors and is often unable to have a complex effect on all factors at once, which leads to the need to combine medications. Conclusions. Since conservative therapy ED cannot be directed at all etiological aspects of this pathology at the same time, a combined drug \"EDELIM\" was developed by SH Pharma. It is a metabolic therapy for ED that addresses the underlying causes of erectile dysfunction and protects the endothelial cells of the corpora cavernosa.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"33 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120844963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamics of urination in patients after radical surgical treatment of cervical cancer.","authors":"M. A. Meshkova, S. Mukhtarulina, V. Romikh, O. Trushina, M. Vekilyan, E. Novikova, A. Kaprin","doi":"10.29188/2222-8543-2022-15-4-130-137","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-4-130-137","url":null,"abstract":"Introduction. The main question of the surgeon in the postoperative period is the possibilities of assessing the function of the lower urinary tract. Symptomatic assessment of urination disorders does not allow to diagnose since many symptoms are subjective and non-specific for a particular disease. Urodynamic study allows to assess the state of the urinary system and determine further tactics. Methods and materials. The study included 173 patients with morphologically verified cervical cancer IB1-IIB stages who underwent radical hysterectomy (RH). The main group consisted of 26 patients after RH type С1 using the water-jet technique. The comparison group A included 79 patients who underwent RH type С1 with the traditional technique. The comparison group B included 52 patients who accepted radical hysterectomy RH type C2. All patients underwent uroflowmetry at the preoperative and postoperative stages in order to exclude dysfunction of the lower urinary tract. Results. In a comparative study of the parameters of uroflowmetry before surgery and 2 months after surgical treatment in patients of the main group, significant differences were obtained in such parameters as the average and maximum velocity of urine flow. In control group A, statistically significant differences were obtained in such parameters as the average urine flow rate, maximum urine flow rate, urine flow time, and the volume of residual urine. In control group B, all indicators had significant differences, with the exception of the volume of urine excreted. Conclusion. Comparative results before surgery and 2 months after surgical treatment in the main group indicate the advantage of the water jet dissection technique as the most precise and nerve-sparing method.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133072109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined minimally invasive surgery for stones and tumors of the ipsilateral kidney.","authors":"A. Panferov, V. Elagin, E. Bekreev","doi":"10.29188/2222-8543-2022-15-4-42-47","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-4-42-47","url":null,"abstract":"Introduction. According to epidemiological studies, the incidence of urolithiasis in the world is about 20%, and the number of patients with this pathology is steadily increasing. Renal cell carcinoma shows the similar dynamics of case growth. The development of diagnostic methods has increased the detectability of combinations of these pathologies, and therefore the urgency of the issue of simultaneous interventions in such patients raises no doubts. Objective. To determine the efficacy and safety of the simultaneous interventions of a stone and a kidney mass of the ipsilateral kidney. Materials and methods. Nine patients with combination of kidney stones and masses of the ipsilateral kidney with indications for the operative treatment were included in the investigation. Results. Laparoscopic kidney resection with pyelolithotomy was performed in all patients in a simultaneously. There was no conversion to open surgery, significant postoperative complications and lethal outcomes. The stent-catheter was removed 4 weeks after the operation. A clinical observation is presented demonstrating the successful treatment of a patient with serious diseases (stones of the right kidney, stones of the right ureter and neoplasm of the right kidney) in one combined surgical treatment. The choice of a simultaneous treatment method in this category of patients, in our opinion, helps prevent the development of intra- and postsurgical complications during staged treatment. The lack of clinical guidelines, as well as the few publications available in the form of clinical examples on the subject are available, creates the need to develop a unified approach to managing patients with a combination of urolithiasis and tumors of the ipsilateral kidney. Conclusion. Combined interventions for ipsilateral kidney stones and masses are safe treatment methods with short rehabilitation period.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"23 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114021420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review of modern techniques of surgical correction of the short frenulum of the penis.","authors":"A. Ryzhkov, S. Sokolova, I. Shormanov","doi":"10.29188/2222-8543-2022-15-4-108-114","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-4-108-114","url":null,"abstract":"Introduction. Short frenulum of the penis (frenulum breve) is a condition associated with a decrease in the length of the frenulum of the penis and/or a decrease in its elasticity. A number of different techniques have been proposed for the surgical treatment of a short frenulum of the penis, from a simple incision (frenulotomy) to complex frenuloplasty and frenulum grafting techniques. Purpose of the study. To assess the results of various surgical techniques in the treatment of frenulum brevis by examining the current evidence base in the world literature. Materials and methods. A search was made for publications in the international database MEDLINE on the platform PubMed, in the scientific electronic library eLibrary.ru and in the Google Scholar search engine. Results. A total of 12 publications were selected. Selected publications were represented by retrospective cohort studies and case series. 3 studies evaluated the results of frenulotomy (frenulectomy), 8 – different methods of frenuloplasty and one – circumcision in the treatment of a short frenulum of the penis. Conclusion. The results of the literature review showed that all techniques of surgical correction of the short frenulum of the penis demonstrate excellent early functional and aesthetic results, with a minimum number of postoperative complications. The best results in the treatment of a short frenulum of the penis can be achieved by choosing the optimal surgical technique in each case.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"361 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115925040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of patients with chronic calculous pyelonephritis.","authors":"F. Asfandiyarov, V. Kruglov, K. Seidov, V. Lyashenko, E. S. Kalashnikov","doi":"10.29188/2222-8543-2022-15-4-122-128","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-4-122-128","url":null,"abstract":"Introduction. Frequent complications of kidney stone disease (KSD) are infectious and inflammatory processes in the organs of the genitourinary system, the most important of which is pyelonephritis. Adhering to a restrained tactic with small caliceal calculi, we observe a significant number of patients with chronic calculous non-obstructive pyelonephritis. Conservative treatment of these patients presents great practical difficulties, as it involves the mandatory parallel treatment of two diseases – pyelonephritis and KSD. The aim of this prospective study was to investigate the effectiveness of conservative therapy in patients with chronic calculous pyelonephritis. Materials and methods. The study included 100 patients with a verified diagnosis of chronic calculous pyelonephritis against the background of existing small caliceal calculi (up to 10 mm). Patients were divided into 2 groups, comparable in terms of the main evaluated criteria. Patients of the first (control) group (40 people) received etiotropic antibiotic course therapy in combination with antispasmodics and immunomodulators. Patients of the second (main) group (60 people) additionally for 3 months took the phytocomplex Onpelvicit 1 capsule 3 times a day under the control of urine pH. Results. At the control examination after 3 months in the group of patients treated with Onpelvicit the frequency of exacerbations of chronic pyelonephritis was significantly lower than in the control group of patients. In the main group, 50% of patients showed a decrease in the size of the calculus, in 15% of cases – complete litholysis. The noted positive effect in relation to chronic pyelonephritis is obviously associated with the phytocomponents of the drug. The effect on the size of the stones is largely due to the presence of sodium and potassium citrates in the complex. Citrate is one of the main inhibitors of crystallization. This effect is realized in both calcium oxalate and urate nephrolithiasis, although the mechanisms differ. Stabilization of the colloidal state of urine, normalization of the acidity index prevents the crystallization of salts and the growth of calculi. Conclusion. Chronic calculous pyelonephritis, which occurs against the background of small calyx calculi of the kidney, is a variant of a combined pathology that is widely encountered in urological practice. The dominant concept of management of this group of patients is to conduct conservative treatment. A pronounced acid reaction of urine in combination with crystalluria of one kind or another is a significant factor in the progression or recurrence of stone formation and the severe course of the inflammatory process. The present study shows that the correction of these disorders has a positive effect on the course of both diseases.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131342676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the effectiveness and safety of laser enucleation of the prostate in different age groups.","authors":"S. Kotov, R. A. Perov, A. Novikov","doi":"10.29188/2222-8543-2022-15-4-37-41","DOIUrl":"https://doi.org/10.29188/2222-8543-2022-15-4-37-41","url":null,"abstract":"Introduction. The influence of the age phenomenon on the outcome of the surgical treatment of benign prostate hyperplasia (BPH) research is insufficient. Considering the wide use of the more advanced laser enucleation method in the surgical treatment of BPH, there is a need to evaluate the efficiency and safety of this technique among aged patients compared to younger age groups. In this review the task was to evaluate the impact of the age phenomenon on the result of treatment, using the available scientific literature. Materials and methods. Articles were searched in three databases (Pubmed, Scopus and Web of Science) using the following request: «laser enucleation», «prostate», «elderly patients», «older patients» and «age». The unsystematic review of 7 works in English containing original data demonstrated the results of different types of enucleation among the patients with a clear stratification of groups by age for the period 2013-2022 was made. Results. Тhe absolute majority of studies do not show significant differences between the age groups regarding the preoperative IPSS, Qmax, post-void residual (PVR), however, a high frequency of chronic diseases in the older age group is noticed. In most studies, no significant differences in a number of complications according to Clavien-Dindo were found. Only in one study P. Gild et al., where large samples were researched, the frequency of blood transfusions and a number of complications ≥3b, were much higher in a group of patients over 80 y.o. and older comparing to younger-aged groups: 0 (0%), 8 (1,3%), 22 (2,7%), 14 (8,2%) for the group under 60 years old, 60-69 years old, 70-79 years old, 80 years and older, respectively (p<0,001); 2 (1,5%), 12 (1,9%), 34 (3,9%), 13 (7,1%), for these groups, respectively (p=0,02). Regarding the postoperative Qmax, despite of significant improvement of this indicator in all age groups, worse results are noticed in older patients group comparing to the results of patients in younger groups. However, the tendency to balance the marked differences with a long observation period is also noticed. Conclusions. Laser enucleation of the prostate is the effective and safe method for prostatic hyperplasia treatment for the patients of any age. However, available data about bad results after the surgical treatment among elderly patients and a higher frequency of complications show the need of the further research of this topic and evaluation of the surgical treatment at an earlier age.","PeriodicalId":123040,"journal":{"name":"Experimental and Сlinical Urology","volume":"122 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124624547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}