Experimental and Clinical Gastroenterology最新文献

Comparative value of controlled attenuation (CAPc) and continuous controlled attenuation (CAP) parameters for different stages of non-alcoholic fatty liver disease 非酒精性脂肪肝不同阶段的受控衰减（CAPc）和连续受控衰减（CAP）参数的比较值

Experimental and Clinical Gastroenterology Pub Date : 2024-03-26 DOI: 10.31146/1682-8658-ecg-222-2-55-63

A. A. Goncharov, A. Sasunova, V. A. Isakov

引用次数: 0

COVID-19 liver damage. Features of laboratory and instrumental diagnostics COVID-19 肝损伤。实验室和仪器诊断的特点

Experimental and Clinical Gastroenterology Pub Date : 2024-03-26 DOI: 10.31146/1682-8658-ecg-219-11-146-152

S. V. Tarasenko, D. A. Glotov, O. D. Peskov, S. N. Sokolova, U. V. Zhuchkova, T. S. Rakhmaev, I. Bakonina, A. Bogomolov, D. O. Tyulenev, S. N. Brovkina, S. G. Bykova

{"title":"COVID-19 liver damage. Features of laboratory and instrumental diagnostics","authors":"S. V. Tarasenko, D. A. Glotov, O. D. Peskov, S. N. Sokolova, U. V. Zhuchkova, T. S. Rakhmaev, I. Bakonina, A. Bogomolov, D. O. Tyulenev, S. N. Brovkina, S. G. Bykova","doi":"10.31146/1682-8658-ecg-219-11-146-152","DOIUrl":"https://doi.org/10.31146/1682-8658-ecg-219-11-146-152","url":null,"abstract":"The aim of the study - to analyze the pathogenesis of liver damage in COVID-19, as well as to study the features of diagnosis. Research materials: literature and own data on the peculiarities of the pathogenesis of liver damage were analyzed, as well as an assessment of laboratory and instrumental diagnostics in patients with COVID-19. The results of the research. In patients, liver damage was manifested by an increase in liver enzymes, as well as a diffuse decrease in its density during CT. The severity of the disease is caused by a cytokine storm caused by a dysfunctional immune response to the virus, viral virulence factors, as well as the presence of concomitant diseases, especially those associated with liver pathology, such as cirrhosis or steatosis. Conclusions. The new COVID-19 coronavirus infection caused by SARS-CoV-2 continues to spread worldwide. The main target is the organs of the respiratory system. However, among the patients with COVID-19, there were lesions of the central nervous system, intestines, myocardium and liver. Liver dysfunction in most cases should be considered as a result of secondary damage due to CVD, ARDS, hypoxia, multiple organ failure, exposure to immune factors, and taking hepatotoxic drugs.","PeriodicalId":12262,"journal":{"name":"Experimental and Clinical Gastroenterology","volume":"120 49","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140378669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostics of the body composition of an elderly person to assess the prognosis of his health 诊断老年人的身体成分，以评估其健康预后

Experimental and Clinical Gastroenterology Pub Date : 2024-03-26 DOI: 10.31146/1682-8658-ecg-222-2-89-100

S. Bulgakova, D. P. Kurmaev, E. Treneva

引用次数: 0

Small intestinal polyps in adults: complications, diagnosis and treatment problems 成人小肠息肉：并发症、诊断和治疗问题

Experimental and Clinical Gastroenterology Pub Date : 2024-03-26 DOI: 10.31146/1682-8658-ecg-219-11-75-80

I. V. Melnyk

{"title":"Small intestinal polyps in adults: complications, diagnosis and treatment problems","authors":"I. V. Melnyk","doi":"10.31146/1682-8658-ecg-219-11-75-80","DOIUrl":"https://doi.org/10.31146/1682-8658-ecg-219-11-75-80","url":null,"abstract":"A case from practice is presented, demonstrating the development of small-intestinal intussusception in a patient, the pathogenetic cause of which was polyps of the small intestine. Despite the fact that the patient twice, before entering the surgical clinic with acute intestinal obstruction, came to the attention of medical workers (the first time with signs of gastrointestinal bleeding, the second time with abdominal pain), the patient was not properly examined, although, retrospectively, it can be assumed that the arsenal of diagnostic methods that were at the disposal of physicians made it possible to make a correct clinical diagnosis. With a very high degree of probability, it can be argued that in both cases, the cause of the patient's problems was the polyps of the small intestine. During the last hospitalization, the patient, despite the preoperative diagnosis that was not entirely accurate in terms of the wording, but absolutely correct in terms of tactics, was promptly performed an adequate surgical intervention in terms of volume. Particular attention of surgeons is drawn to the mandatory need for careful palpation and visual revision of all parts of the small intestine when performing surgical interventions for completed small intestinal intussusceptions.","PeriodicalId":12262,"journal":{"name":"Experimental and Clinical Gastroenterology","volume":"110 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140379151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gastritis and peptic ulcers are associated with the lower levels of plasma lipids: possible involvement of histamine 胃炎和消化性溃疡与血浆脂质水平降低有关：组胺可能参与其中

Experimental and Clinical Gastroenterology Pub Date : 2024-03-26 DOI: 10.31146/1682-8658-ecg-219-11-5-11

Laiegh Mohsen, Fakheri Hafez, Rasouli Mehdi

{"title":"Gastritis and peptic ulcers are associated with the lower levels of plasma lipids: possible involvement of histamine","authors":"Laiegh Mohsen, Fakheri Hafez, Rasouli Mehdi","doi":"10.31146/1682-8658-ecg-219-11-5-11","DOIUrl":"https://doi.org/10.31146/1682-8658-ecg-219-11-5-11","url":null,"abstract":"Background: Histamine receptors are involved to regulate lipid metabolism, so the hypothesis will arise that pathological states with abnormal histamine levels are associated with altered plasma lipids. Objectives: To study the profile of plasma lipids in patients with gastritis and peptic ulcer (GPU). Methods: In a case-control study, 70 dyspeptic patients were selected according to clinical criteria and using gastroduodenoscopy and compared with sex and age matched normal subjects. Results: There were no significant differences in age, sex, and the prevalence of hypertension and diabetes between two groups. But allergy, the familial history of allergy and dyspeptic and H. pylori infection were more prevalent in case group compared with controls. The levels of the indices of inflammation and body hydration were the same in two groups. Patients with dyspeptic compared with the controls had the lower concentrations of serum triglyceride (139.2±44.3 vs. 153.4±91.3), p≤0.553), total cholesterol (174.6±32.4 vs. 192.8±52.0, p≤0.073, LDLc (93.4±20.2 vs. 105.4±32.2, p≤0.015) and NonHDLc (130.2±38.1 vs. 159.2±42.2, p≤0.008). The level of HDL had not a significant change (43.4±7.8 vs. 43.5±12.7, p≤0.930). Dyspeptic state had negative significant correlation with total cholesterol, LDLc and NonHDLc but not HDLc. Neither the markers of inflammation nor the indices of body hydration had significant correlation with GPU. Conclusions: The GPU patients relative to normal group had the lower levels of serum lipids. The hypolipemic effects may be attributed to increased level of histamine in GPU patients.","PeriodicalId":12262,"journal":{"name":"Experimental and Clinical Gastroenterology","volume":"108 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140379466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Obesity provokes the development of bronchopulmonary pathology and aggravates its course 肥胖会诱发支气管肺部病变并加重其病程

Experimental and Clinical Gastroenterology Pub Date : 2024-03-26 DOI: 10.31146/1682-8658-ecg-222-2-50-54

A. V. Pashentseva, L. Y. Shvan, I. V. Gubareva, G. V. Supornik

引用次数: 0

Tribute to the memory of Zarivchatsky Mikhail Fedorovich - surgeon, organizer of health care, professor of Perm State Medical University 悼念外科医生、保健组织者、彼尔姆国立医科大学教授扎里夫查茨基-米哈伊尔-费多罗维奇

Experimental and Clinical Gastroenterology Pub Date : 2024-03-26 DOI: 10.31146/1682-8658-ecg-219-11-163-166

S. Styazhkina, R. R. Shaymukhametov, T. E. Chernyshova, D. G. Amarantov, S. A. Denisov

引用次数: 0

History of discovery of ileo-caecal valve: Josef Hyrtl’s version 回肠盲肠瓣的发现史：约瑟夫-希特尔的版本

Experimental and Clinical Gastroenterology Pub Date : 2024-03-26 DOI: 10.31146/1682-8658-ecg-219-11-160-162

S. Kutia, N. Nikolaeva

引用次数: 0

Adipocines and longevity: connections and paradoxes 脂肪素与长寿：联系与悖论

Experimental and Clinical Gastroenterology Pub Date : 2024-03-26 DOI: 10.31146/1682-8658-ecg-222-2-149-155

E. Treneva, S. Bulgakova, D. P. Kurmaev, L. A. Sharonova, Y. Dolgikh

{"title":"Adipocines and longevity: connections and paradoxes","authors":"E. Treneva, S. Bulgakova, D. P. Kurmaev, L. A. Sharonova, Y. Dolgikh","doi":"10.31146/1682-8658-ecg-222-2-149-155","DOIUrl":"https://doi.org/10.31146/1682-8658-ecg-222-2-149-155","url":null,"abstract":"Adipose tissue is an active endocrine organ that regulates energy homeostasis throughout the body by releasing hundreds of biologically active substances called adipokines. Dysregulation of adipokines is a key feature of insulin resistance with the development of metabolic syndrome and type 2 diabetes mellitus, which is an age-dependent pathology. In turn, dysregulation of adipokines and insulin resistance are associated with the development of metabolic deficiency and senile asthenia syndrome in older age groups. Previous studies have shown that the absence of insulin resistance and low prevalence of diabetes among centenarians are metabolic prerequisites for increased lifespan, suggesting a possible role for adipokine homeostasis in healthy longevity. Among numerous adipokines, adiponectin is considered a protective factor, showing a negative correlation with major metabolic disorders associated with age and obesity, and a positive association with life expectancy and insulin sensitivity among centenarians. Despite all the apparent protective effects of adiponectin, large-scale epidemiological studies have revealed the opposite aspect of adiponectin as a predictor of all-cause mortality and cardiovascular disease in patients with heart failure as well as kidney disease. In this review, the clinical significance of adiponectin is considered in centenarians from the point of view of the development of the main geriatric syndrome - senile asthenia, as well as cardiovascular risk and mortality.","PeriodicalId":12262,"journal":{"name":"Experimental and Clinical Gastroenterology","volume":"123 27","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140378804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The relationship between gastroesophageal pathogenic reflux and metabolic syndrome 胃食管返流与代谢综合征的关系

Experimental and Clinical Gastroenterology Pub Date : 2024-03-26 DOI: 10.31146/1682-8658-ecg-222-2-131-140

E. D. Bulgakova, E. Shrayner, A. I. Khavkin, G. Lifshits, K. Nikolaychuk, M. Denisov

{"title":"The relationship between gastroesophageal pathogenic reflux and metabolic syndrome","authors":"E. D. Bulgakova, E. Shrayner, A. I. Khavkin, G. Lifshits, K. Nikolaychuk, M. Denisov","doi":"10.31146/1682-8658-ecg-222-2-131-140","DOIUrl":"https://doi.org/10.31146/1682-8658-ecg-222-2-131-140","url":null,"abstract":"Currently, special attention is drawn to the phenomenon of comorbidity of chronic non-infectious diseases. The emergence of comorbidity is facilitated by the high incidence of coexisting diseases. One such combination is GERD and metabolic syndrome (MS). GERD and MS are multifactorial diseases, the pathogenesis of which is intertwined and mutually aggravates each other. Every year throughout the world and the Russian Federation, there is a clear trend towards an increase in the incidence of pathology of the upper gastrointestinal tract, namely gastroesophageal reflux disease (GERD). The prevalence of obesity in Russia over 40 years of observation has increased 4 times among men and 1.5 times among women. Despite the high incidence, to date there is no diagnosis of “metabolic syndrome” (MS) in ICD-10. MS is coded based on its constituent pathologies (obesity, dyslipidemia, insulin resistance, arterial hypertension). Treatment of this comorbid pathology requires a multidisciplinary approach, thereby placing a high burden on the healthcare system. This article displays the features of the pathogenesis and clinical picture of GERD, as well as the combination of this pathology with the components of MS.","PeriodicalId":12262,"journal":{"name":"Experimental and Clinical Gastroenterology","volume":"115 46","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140379066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0