Folia morphologica最新文献_第2页

IGF 1, BDNF, and NGF mediate the neuro-modulatory role of stem cells in acrylamide-induced hippocampal toxic changes in rats. IGF 1、BDNF 和 NGF 在丙烯酰胺诱导的大鼠海马毒性变化中介导干细胞的神经调节作用。

IF 1.2 4区医学

Folia morphologica Pub Date : 2024-09-18 DOI: 10.5603/fm.101454

Nabila Youssef Abdel Halim, Gamal Hosny Mohamed, Ahmed Elhusseiny, Marwa Abdelgwad, Reda Abdelnasser Imam

{"title":"IGF 1, BDNF, and NGF mediate the neuro-modulatory role of stem cells in acrylamide-induced hippocampal toxic changes in rats.","authors":"Nabila Youssef Abdel Halim, Gamal Hosny Mohamed, Ahmed Elhusseiny, Marwa Abdelgwad, Reda Abdelnasser Imam","doi":"10.5603/fm.101454","DOIUrl":"https://doi.org/10.5603/fm.101454","url":null,"abstract":"Background: Acrylamide (ACR), a common industrial chemical, is a strong neurotoxic material. The hippocampus is a brain area of interest mostly affected by Alzheimer's disease. Mesenchymal stem cells (MSCs) usefulness in various neurological diseases including Alzheimer's is being debated. In this work, the authors aim to explore the role of MSCs in ACR-induced hippocampal neurodegeneration and elucidate the mediating mechanism.Materials and methods: For this purpose, ten rats served as control, another ten were injected ACR (i.p. 50 mg/kg/day for 2 weeks), and the last ten rats were injected ACR in addition to MSCs (i.p. 1 × 10⁷ MSCs single injection).Results: ACR induced neurodegenerative histopathological hippocampal changes and adversely altered hippocampal oxidative stress markers SOD, MDA, and GSH. ACR had induced hippocampal demyelination as detected by silver staining. ACR significantly (P < 0.05) up-regulated the ELISA hippocampal TNF-alpha and IL-6 and produced microglial & astrocyte activation (as tracked by Iba1 & GFAP immunohistochemistry respectively). ACR significantly reduced hippocampal PCR gene expression of IGF 1 (insulin growth factor-1), BDNF (brain-derived neurotrophic factor), and NGF (nerve growth factor). MSCs administration had mitigated all the previous deleterious changes.Conclusions: Acrylamide caused detrimental effects on the hippocampus and demonstrably altered the hippocampal architecture. Bone marrow mesenchymal stem cells offered a promising therapeutic role against these neurotoxic effects of acrylamide, presumably through modulation of IGF 1, BDNF, and NGF gene expressions.","PeriodicalId":12251,"journal":{"name":"Folia morphologica","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anatomy of the lymphatics in normal stomach and gastric carcinomas. 正常胃和胃癌的淋巴管解剖。

IF 1.2 4区医学

Folia morphologica Pub Date : 2024-09-18 DOI: 10.5603/fm.101667

Dimosthenis Chrysikos, Panagiotis Kanavaros, Alexandra Barbouti, Ameer Shehade, Dimitrios Liatsos, Alexandros Samolis, Thoedore Troupis

引用次数: 0

Zygomaticofacial foramen in dry adult human skulls: a morphological study. 干成人头骨中的颧面孔：形态学研究。

IF 1.2 4区医学

Folia morphologica Pub Date : 2024-09-18 DOI: 10.5603/fm.100537

Stanislav Malakhov, Petra Lukacikova, Andrej Mifkovic, Ladislava Wsolova, Oleg Vovk, Stefan Polak

{"title":"Zygomaticofacial foramen in dry adult human skulls: a morphological study.","authors":"Stanislav Malakhov, Petra Lukacikova, Andrej Mifkovic, Ladislava Wsolova, Oleg Vovk, Stefan Polak","doi":"10.5603/fm.100537","DOIUrl":"https://doi.org/10.5603/fm.100537","url":null,"abstract":"Background: A wide range of medical procedures in the zygomatic region in maxillofacial surgery, implantology, and aesthetic medicine requires a detailed study of the zygomaticofacial foramen (ZFF) due to the high risk of damage to its contents during manipulation.This study aimed to estimate the shape, diameter, and location of ZFF and their relationships with anatomical landmarks.Materials and methods: A studywas conductedon 53 dry adult human skulls. Standard morphometric measurementswere takenusing sliding calipers.The number, diameter, shape, and location of ZFF were notedon both sides, andthe distances between the ZFF and surrounding anatomical landmarks were measured.Conventional statistical methods were usedto evaluate the data.Results: Out of 106 sides, no ZFFwas noticedin 2.8%, one foramen was found in 40.6%, two foramina were found in 39.6%, threein 10.4%, four in 4.7%, andfive in 1.9%. The vertical diameter was 0.98 ± 0.35 mm, while the transverse diameter was 0.87 ± 0.31 mm. The shape of the ZFF was oval in 67%, round in 26.2%, semilunar in 4.9%, and irregular in 1.9%. The distance from the ZFF to the infraorbital margin was 6.63 ± 2.09 mm, tothe frontozygomatic suture was 26.24 ± 3.49 mm, tothe zygomaticomaxillarysuture,was 19.75 ± 3.55 mm, tothe zygomaticotemporal suture was 22.31 ± 3.98 mm and, to the most prominent point of the zygomatic bone was 8.03 ± 2.64 mm.Conclusions: The variations in the number and location of ZFF mustbe consideredwhile performing regional blockanesthesia,and surgical or aesthetic procedures in the zygomatic region.","PeriodicalId":12251,"journal":{"name":"Folia morphologica","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of aging on mast cell density in human skin: a comparative analysis of photoexposed and photoprotected regions. 衰老对人体皮肤肥大细胞密度的影响：光暴露区和光保护区的对比分析。

IF 1.2 4区医学

Folia morphologica Pub Date : 2024-09-18 DOI: 10.5603/fm.102163

Snezana Lestarevic, Sladjana Savic, Mirjana Dejanovic, Milica Mijovic, Predrag Mandic, Dragan Marjanovic, Milan Filipovic, Ivan Branimira Rancic, Teodora Jorgacevic

{"title":"The effect of aging on mast cell density in human skin: a comparative analysis of photoexposed and photoprotected regions.","authors":"Snezana Lestarevic, Sladjana Savic, Mirjana Dejanovic, Milica Mijovic, Predrag Mandic, Dragan Marjanovic, Milan Filipovic, Ivan Branimira Rancic, Teodora Jorgacevic","doi":"10.5603/fm.102163","DOIUrl":"https://doi.org/10.5603/fm.102163","url":null,"abstract":"Background: Mast cells are mononuclear cells originating from bone marrow. They produce various biologically active substances, which allow them to actively participate in immune and inflammatory processes associated with intrinsic and extrinsic skin aging. This research focused on distribution and density of mast cells in healthy skin in different stages of skin aging.Material and methods: This project included samples of photoexposed and photoprotected skin, obtained from 90 cadavers aged 0-82 years. The samples were classified into five age groups: newborns, young age, middle age, senior age and the oldest age. In order to visualize the mast cells, we have employed several histochemical staining protocols.Results: The number of mast cells of the photoexposed skin significantly correlated to the individual's age. The number of mast cells of the photoprotected skin was in general statistically significantly lower in younger compared to older groups; however, the correlation of the mast cell density in photoprotected skin and the age did not reach statistical significance. In middle age, senior age and the oldest age groups, a significantly higher number of mast cells was recorded in the skin of the photoexposed compared to photoprotected region.Conclusions: The increase in mast cell density correlated with age only in photoexposed skin. Age-related higher accumulation of dermal mast cells in photoexposed skin can be an important factor in the photoaging process, as well as the contributing factor in the occurrence of skin cancer.","PeriodicalId":12251,"journal":{"name":"Folia morphologica","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Frequency, localization, and diameter of the accessory maxillary ostium and its relationship with sinus pathologies and nasal cavity variations: an anatomical study based on cone beam computed tomography. 上颌副骨的频率、定位和直径及其与鼻窦病变和鼻腔变异的关系：基于锥形束计算机断层扫描的解剖学研究。

IF 1.2 4区医学

Folia morphologica Pub Date : 2024-09-18 DOI: 10.5603/fm.101465

Nurşat Türker, Duygu Göller Bulut

{"title":"Frequency, localization, and diameter of the accessory maxillary ostium and its relationship with sinus pathologies and nasal cavity variations: an anatomical study based on cone beam computed tomography.","authors":"Nurşat Türker, Duygu Göller Bulut","doi":"10.5603/fm.101465","DOIUrl":"https://doi.org/10.5603/fm.101465","url":null,"abstract":"Background: The aim of the present study was to determine the presence, frequency, and characteristics of the accessory maxillary ostium (AMO) in a specific Turkish population using cone beam computed tomography (CBCT) and to evaluate the frequency of pathologies and anatomical variations in the nasal cavity and maxillary sinus and to assess their relationship with the AMO.Materials and methods: This study retrospectively evaluated the presence of AMO in CBCT images of 543 patients, the patients' age, gender, and dentition status, the presence of nasal cavity variations and maxillary sinus pathologies, and their relationship to the presence of AMO. Descriptive values of the data and comparative results were included.Results: 249 males and 294 females participated in the study. The majority of right and left sinus pathologies were irregular type mucosal thickenings (right/left; 14%, 14.9%). The majority of nasal variations were concha bullosa (right/left; 37.9%, 39.2%). There were 148 (27.3%) and 138 (25.4%) AMOs on the right and left sides, respectively, with the majority in the middle position (right/left; 21.2%/17.5%). The frequency of right and left AMOs was significantly higher in men (P = 0.019 and P = 0.020, respectively). The left AMO frequency was significantly higher in patients with left-sided sinus pathology (P = 0.003). AMO diameters were larger in men (right/left P = 0.010 and P = 0.021, respectively), and left AMO diameter was significantly larger in patients with left sinus pathology (P = 0.006).Conclusions: Before any surgical intervention in the maxillary sinus and osteomeatal region, the presence and location of the AMO, existing pathologies, and variations in the region should be carefully checked to avoid complications.","PeriodicalId":12251,"journal":{"name":"Folia morphologica","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carrying angle among young adults of Saudi Arabia and its correlation with demographic characteristics: A cross sectional study. 沙特阿拉伯年轻成年人的携带角度及其与人口特征的相关性：一项横断面研究。

IF 1.2 4区医学

Folia morphologica Pub Date : 2024-09-11 DOI: 10.5603/fm.101752

Jaya Shanker Tedla, Raghu Jetti, Batool Abdulelah Alkhamis, Ravi Shankar Reddy, Mastour Saeed Alshahrani, Devika Rani Sangadala, Vikram Sreenivasa Rao, Debjani Mukherjee, Ahlam Mohammed Alamri, Hind Khalid Ali AlQahtani

{"title":"Carrying angle among young adults of Saudi Arabia and its correlation with demographic characteristics: A cross sectional study.","authors":"Jaya Shanker Tedla, Raghu Jetti, Batool Abdulelah Alkhamis, Ravi Shankar Reddy, Mastour Saeed Alshahrani, Devika Rani Sangadala, Vikram Sreenivasa Rao, Debjani Mukherjee, Ahlam Mohammed Alamri, Hind Khalid Ali AlQahtani","doi":"10.5603/fm.101752","DOIUrl":"https://doi.org/10.5603/fm.101752","url":null,"abstract":"Background: The angle between the median axes of the forearm and arm is called the carrying angle (CA). Sex differences in CA and its relation to age, height, weight, and BMI are unclear. The aim of the present study was to measure the CA in male and female subjects in the Saudi population and correlate it with the above variables.Materials and methods: A digital goniometer was used to measure CA in 181 males and 165 females. Information on age, height, weight, and BMI was also recorded.Results: CA showed differences based on sex, though was independent of age, height, weight, and BMI. Hormonal factors may influence CA and could explain larger CA values in female subjects.Conclusions: CA measurement in specific population groups contributes to the successful management of several pathological conditions of the elbow and aids in the design of elbow orthotics and prosthetics.","PeriodicalId":12251,"journal":{"name":"Folia morphologica","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Renal structural changes and apelin receptor expression in spontaneously hypertensive rats: implications for hypertension-induced kidney injury. 自发性高血压大鼠肾脏结构变化和凋亡素受体表达：对高血压诱发肾损伤的影响

IF 1.2 4区医学

Folia morphologica Pub Date : 2024-09-11 DOI: 10.5603/fm.100637

Stancho Stanchev, Lyubomir Gaydarski, Iva N Dimitrova, Georgi Kotov, Boycho Landzhov, Vidin Kirkov, Alexandar Iliev

{"title":"Renal structural changes and apelin receptor expression in spontaneously hypertensive rats: implications for hypertension-induced kidney injury.","authors":"Stancho Stanchev, Lyubomir Gaydarski, Iva N Dimitrova, Georgi Kotov, Boycho Landzhov, Vidin Kirkov, Alexandar Iliev","doi":"10.5603/fm.100637","DOIUrl":"https://doi.org/10.5603/fm.100637","url":null,"abstract":"Background: Arterial hypertension is a primary risk factor for kidney disease. Recent advances have implied a potential link between the apelin system and renal homeostasis.Materials and methods: We used 6- and 12-month-old spontaneously hypertensive rats and age-matched normotensive controls to assess the changes in the renal expression of the apelin receptor by immunohistochemical method. The study also evaluated correlations between the renal apelin receptor's expression and renal injury indicators.Results: The histological analysis showed elevated glomerular sclerosis and tubulointerstitial damage indices in both groups of hypertensive rats compared to age-matched controls. Older rats within each group exhibited higher scores than younger ones. The immunohistochemical analysis revealed varying apelin receptor expression patterns, with tubular expression intensifying both with hypertension severity and age. Glomerular expression was notably higher in older hypertensive rats compared to normotensive controls. We reported significant positive correlations between glomerular apelin receptor expression and glomerular sclerosis index in older hypertensive animals. Similarly, a positive correlation between tubular apelin receptor expression and tubulointerstitial damage index was discovered in hypertensive rats, suggesting hypertension-related changes in apelin receptor expression and renal damage.Conclusions: Our study found kidney changes and varying apelin receptor correlations in hypertensive rat kidneys, suggesting complex roles needing research.","PeriodicalId":12251,"journal":{"name":"Folia morphologica","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The complete anatomy of the azygos vein: a meta-analysis with clinical implications. 颧静脉的完整解剖：具有临床意义的荟萃分析。

IF 1.2 4区医学

Folia morphologica Pub Date : 2024-09-11 DOI: 10.5603/fm.101166

Dawid Plutecki, Michał Bonczar, Patryk Ostrowski, Bernard Solewski, Karolina Brzegowy-Solewska, Jerzy Walocha, Mateusz Koziej

{"title":"The complete anatomy of the azygos vein: a meta-analysis with clinical implications.","authors":"Dawid Plutecki, Michał Bonczar, Patryk Ostrowski, Bernard Solewski, Karolina Brzegowy-Solewska, Jerzy Walocha, Mateusz Koziej","doi":"10.5603/fm.101166","DOIUrl":"https://doi.org/10.5603/fm.101166","url":null,"abstract":"Background: The azygos vein (AV) plays a crucial role in the mediastinal region, exhibiting considerable variability in its anatomy and relationship with surrounding structures. This study aims to assess the morphometry and anatomy of the AV through a comprehensive meta-analysis of studies reporting extractable data on this vessel.Materials and methods: Major online medical databases such as PubMed, Scopus, ScienceDirect, Web of Science, SciELO, BIOSIS, Current Content Connect, Korean Journal Database and Wiley online library were searched to gather all relevant studies regarding the anatomical characteristics of the AV.Results: The results of the present meta-analysis comprised 40 studies, categorized into eight groups for data analysis. The mean AV diameter at its origin was set at 3.86 mm (SE = 0.84). The most prevalent was type IIB, with a prevalence of 40.23% (95% CI: 29.06-51.92%). The pooled prevalence of the right subcostal and right ascending lumbar veins forming the AV was 73.82% (95% CI: 55.77-88.67%).Conclusions: The AV exhibits a high degree of variability regarding its origin, trajectory, and connections with the hemiazygos system. The most prevalent type of AV, according to the Anson and McVay classification, was Type II (transitional type). Moreover, the vein was found to be formed by the right subcostal and the right ascending lumbar veins in the majority of the cases. This is the most comprehensive and current assessment of AV morphometry and anatomy to date. The findings are a valuable resource for physicians, especially surgeons performing various procedures in the mediastinum.","PeriodicalId":12251,"journal":{"name":"Folia morphologica","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Morphological and morphometric analysis of the Sacral Hiatus using lumbosacral spine CT scans: clinical relevance in Caudal Epidural Analgesia. 利用腰骶椎 CT 扫描对骶骨间隙进行形态学和形态计量学分析：与尾硬膜外镇痛的临床相关性。

IF 1.2 4区医学

Folia morphologica Pub Date : 2024-08-28 DOI: 10.5603/fm.101363

Apurba Patra, Harmeet Kaur, Priti Chaudhary, Adil Asghar, Navneh Samagh, Jerzy Andrzej Walocha, Bartosz Rutowicz, Karolina Brzegowy-Solewska, Dariusz Lusina, Janusz Skrzat

{"title":"Morphological and morphometric analysis of the Sacral Hiatus using lumbosacral spine CT scans: clinical relevance in Caudal Epidural Analgesia.","authors":"Apurba Patra, Harmeet Kaur, Priti Chaudhary, Adil Asghar, Navneh Samagh, Jerzy Andrzej Walocha, Bartosz Rutowicz, Karolina Brzegowy-Solewska, Dariusz Lusina, Janusz Skrzat","doi":"10.5603/fm.101363","DOIUrl":"https://doi.org/10.5603/fm.101363","url":null,"abstract":"Background: To conduct a morphological and morphometric analysis of the sacral hiatus (SH) using lumbosacral spine CT scans and to evaluate its clinical relevance in caudal epidural analgesia (CEA).Materials and methods: This retrospective study analyzed 77 lumbosacral spine CT scans from a diverse patient population. The shape of the SH was classified into common types: inverted U, inverted V, irregular, and bilobed. Morphometric measurements included the length, width, and depth at the apex of the SH. The apex level of the SH was also determined in relation to the sacral vertebrae, and statistical analysis was performed to identify any correlation between the apex level and the morphometric dimensions.Results: The most frequent SH shape was inverted U (68.83%), followed by inverted V (20.77%), irregular (9%), and a single instance of a bilobed shape (1.29%). The apex of the SH was most commonly located at the level of the S4 vertebra (75.32%), followed by the S3 vertebra (20.77%), S5 in two (2.59) and S2 in one (1.29%). No significant correlation was found between the level of the apex and the length, width, or depth of the SH. These findings indicate a high degree of anatomical variability in the SH, independent of the apex level.Conclusions: The anatomical variability of the SH, as observed in this study, underscores the need for individualized assessment during CEA. The lack of correlation between the apex level and the morphometric dimensions of the SH highlights the importance of imaging modalities such as ultrasound or fluoroscopy to ensure precise localization and effective analgesia administration. These insights can improve clinical outcomes by enhancing the accuracy and safety of caudal epidural procedures.","PeriodicalId":12251,"journal":{"name":"Folia morphologica","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142079826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unusual morphology of an aberrant right subclavian artery: a case report and systematic review of cadaveric studies . 右锁骨下动脉异常形态：病例报告和尸体研究系统回顾 .

IF 1.2 4区医学

Folia morphologica Pub Date : 2024-08-28 DOI: 10.5603/fm.99244

Kseniia Panteleeva, Dalia Bornstein, Neel Badhe, Perry Maskell, Cecilia Brassett, Sarah Fawcett

{"title":"Unusual morphology of an aberrant right subclavian artery: a case report and systematic review of cadaveric studies .","authors":"Kseniia Panteleeva, Dalia Bornstein, Neel Badhe, Perry Maskell, Cecilia Brassett, Sarah Fawcett","doi":"10.5603/fm.99244","DOIUrl":"https://doi.org/10.5603/fm.99244","url":null,"abstract":"Background: An aberrant right subclavian artery (ARSA) is a rare vascular anomaly defined by the origin of the right subclavian artery from the aorta, distal to the left subclavian artery (LSA). An ARSA was found in an 83-year-old female during cadaveric dissection for anatomy teaching, which had an unusually narrow lumen compared to previously reported cases.Materials and methods: The specific morphology of this ARSA variant was characterised by further dissection and measurements. A systematic review of cadaveric case reports with quantitative evaluation of ARSA dimensions was conducted for comparison with this case.Results: This ARSA variant exhibited an unusually narrow lumen (8.22 mm²) compared to the LSA (152.55²), with an ARSA: LSA ratio of 0.24. The systematic review included 17 studies with 23 cases of ARSAs. Of these cases, 20 contained details of ARSA diameter, 19 of which were wider than in this case. In all studies where both ARSA and LSA diameters were measured, ARSA was found to be significantly wider than LSA (mean ratio of ARSA to LSA: 1.49, range: 1.09-2.00). Several other variations were reported in these studies, such as concomitant aortic arch branch anomalies and differing origins of ARSA as defined by vertebral level and relation to the aortic arch.Conclusions: This case report presents an unusually narrow ARSA which has not been previously described in the literature. As there is limited evidence on how ARSA morphology affects clinical outcomes, further research is needed to better inform management of ARSAs.","PeriodicalId":12251,"journal":{"name":"Folia morphologica","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142079827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0