Michèle Weber, Matthias Hannes Diebold, Peter Wiesli, Andreas David Kistler
{"title":"Accuracy of Flash Glucose Monitoring in Hemodialysis Patients With and Without Diabetes Mellitus.","authors":"Michèle Weber, Matthias Hannes Diebold, Peter Wiesli, Andreas David Kistler","doi":"10.1055/a-1978-0226","DOIUrl":"https://doi.org/10.1055/a-1978-0226","url":null,"abstract":"<p><strong>Aims: </strong>Glucose and insulin metabolism are altered in hemodialysis patients, and diabetes management is difficult in these patients. We aimed to validate flash glucose monitoring (FGM) in hemodialysis patients with and without diabetes mellitus as an attractive option for glucose monitoring not requiring regular self-punctures.</p><p><strong>Methods: </strong>We measured interstitial glucose using a FreeStyle Libre device in eight hemodialysis patients with and seven without diabetes mellitus over 14 days and compared the results to simultaneously performed self-monitoring of capillary blood glucose (SMBG).</p><p><strong>Results: </strong>In 720 paired measurements, mean flash glucose values were significantly lower than self-measured capillary values (6.17±2.52 vs. 7.15±2.41 mmol/L, p=1.3 E-86). Overall, the mean absolute relative difference was 17.4%, and the mean absolute difference was 1.20 mmol/L. The systematic error was significantly larger in patients without vs. with diabetes (- 1.17 vs. - 0.82 mmol/L) and on dialysis vs. interdialytic days (-1.09 vs. -0.90 mmol/L). Compared to venous blood glucose (72 paired measurements), the systematic error of FGM was even larger (5.89±2.44 mmol/L vs. 7.78±7.25 mmol/L, p=3.74E-22). Several strategies to reduce the systematic error were evaluated, including the addition of +1.0 mmol/L as a correction term to all FGM values, which significantly improved accuracy.</p><p><strong>Conclusions: </strong>FGM systematically underestimates blood glucose in hemodialysis patients but, taking this systematic error into account, the system may be useful for glucose monitoring in hemodialysis patients with or without diabetes.</p>","PeriodicalId":12241,"journal":{"name":"Experimental and Clinical Endocrinology & Diabetes","volume":"131 3","pages":"132-141"},"PeriodicalIF":1.8,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f9/d2/10-1055-a-1978-0226.PMC9998185.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9088415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Hummel, Martin Füchtenbusch, Wilgard Battefeld, Christoph Bührer, Tanja Groten, Thomas Haak, Franz Kainer, Alexandra Kautzky-Willer, Andreas Lechner, Thomas Meissner, Christine Nagel-Reuper, Ute Schäfer-Graf, Thorsten Siegmund
Bernhard Kulzer, Christian Albus, Stephan Herpertz, Johannes Kruse, Karin Lange, Florian Lederbogen, Frank Petrak
{"title":"Psychosocial Factors and Diabetes.","authors":"Bernhard Kulzer, Christian Albus, Stephan Herpertz, Johannes Kruse, Karin Lange, Florian Lederbogen, Frank Petrak","doi":"10.1055/a-1946-3863","DOIUrl":"https://doi.org/10.1055/a-1946-3863","url":null,"abstract":"Affiliations 1 Diabetes Center Bad Mergentheim, Research Institute of the Diabetes Academy (Forschungsinstitut der Diabetes Akademie – FIDAM), Mergentheim, Germany 2 Department of Psychosomatic Medicine and Psychotherapy, University of Cologne, Cologne, Germany 3 Department of Psychosomatic Medicine and Psychotherapy, LWL University Hospital of the Ruhr-University Bochum, Bochum, Germany 4 Department of Psychosomatics and Psychotherapy of the Justus-Liebig-University Giessen and Philipps University Marburg, Marburg, Germany 5 Research and Teaching Unit of Medical Psychology, Medical School, Hannover, Germany 6 Joint practice Weimer/Tabakhtory-Fard; Marburg, Heidelberg, Germany","PeriodicalId":12241,"journal":{"name":"Experimental and Clinical Endocrinology & Diabetes","volume":"131 1-02","pages":"94-109"},"PeriodicalIF":1.8,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9427151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ludwig Merker, Thomas Ebert, Martina Guthoff, Berend Isermann
{"title":"Nephropathy in Diabetes.","authors":"Ludwig Merker, Thomas Ebert, Martina Guthoff, Berend Isermann","doi":"10.1055/a-1946-3783","DOIUrl":"https://doi.org/10.1055/a-1946-3783","url":null,"abstract":"recommendation 1: Additional information added to the general measures reason: Important measures for the self-management of CKD supporting reference: [11] recommendation 2: Blood pressure target value lowered reason: Current guideline recommendation supporting reference: [12] recommendation 3: Use of non-steroidal mineralocorticoid receptor antagonists in future reason: New data from endpoint studies supporting reference: [13–14] recommendation 4: Use of some SGLT-2 inhibitors also in stage G4 reason: Newer data supporting reference: [11] Preliminary note","PeriodicalId":12241,"journal":{"name":"Experimental and Clinical Endocrinology & Diabetes","volume":"131 1-02","pages":"61-65"},"PeriodicalIF":1.8,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9428371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stephan Morbach, Michael Eckhard, Ralf Lobmann, Eckhard Müller, Heinrich Reike, Alexander Risse, Gerhard Rümenapf, Maximilian Spraul
{"title":"Diabetic Foot Syndrome.","authors":"Stephan Morbach, Michael Eckhard, Ralf Lobmann, Eckhard Müller, Heinrich Reike, Alexander Risse, Gerhard Rümenapf, Maximilian Spraul","doi":"10.1055/a-1946-3838","DOIUrl":"https://doi.org/10.1055/a-1946-3838","url":null,"abstract":"Affiliations 1 Department of Diabetology and Angiology, Marienkrankenhaus gGmbH, Soest, Germany 2 University Diabetes Center and Interdisciplinary Diabetic Foot Center of Central Hessen, University Hospital Giessen and Marburg GmbH, Location: Giessen and GZW Diabetes Clinic Bad Nauheim, Germany 3 Department of Endocrinology, Diabetology and Geriatrics, Klinikum Stuttgart, Location: Bad Cannstatt, Germany 4 Practice for Diabetology and Nephrology, KfH Kidney Center, Bernkastel-Kues, Germany 5 Dortmund, Germany 6 Diabetes Center at Sophie-Charlotte-Platz, Berlin, Germany 7 Upper Rhine Vascular Center, Department of Vascular Surgery, Diakonissen-Stiftungs-Hospital, Speyer, Germany 8 Diabetes Practice, Rheine, Germany","PeriodicalId":12241,"journal":{"name":"Experimental and Clinical Endocrinology & Diabetes","volume":"131 1-02","pages":"84-93"},"PeriodicalIF":1.8,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9779755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diana Rubin, Anja Bosy-Westphal, Stefan Kabisch, Peter Kronsbein, Marie-Christine Simon, Astrid Tombek, Katharina S Weber, Thomas Skurk
{"title":"Nutritional Recommendations for People with Type 1 Diabetes Mellitus.","authors":"Diana Rubin, Anja Bosy-Westphal, Stefan Kabisch, Peter Kronsbein, Marie-Christine Simon, Astrid Tombek, Katharina S Weber, Thomas Skurk","doi":"10.1055/a-1946-3753","DOIUrl":"https://doi.org/10.1055/a-1946-3753","url":null,"abstract":"Affiliations 1 Vivantes Hospital Spandau, Berlin, Germany 2 Vivantes Humboldt Hospital, Berlin, Germany 3 Institute of Human Nutrition, Faculty of Agriculture and Nutritional Sciences, Christian-Albrechts University of Kiel, Kiel, Germany 4 Department of Endocrinology, Diabetes and Nutritional Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany 5 German Center for Diabetes Research (DZD), Munich, Germany 6 Faculty of Nutrition and Food Sciences, Niederrhein University of Applied Sciences, Mönchengladbach, Germany 7 Institute of Nutrition and Food Sciences, Rhenish Friedrich Wilhelm University of Bonn, Bonn, Germany 8 Diabetes Center Bad Mergentheim, Bad Mergentheim, Germany 9 Institute for Epidemiology, Christian-Albrechts University of Kiel, Kiel, Germany 10 ZIEL – Institute for Food & Health, Technical University Munich, Freising, Germany published online 13.01.2023","PeriodicalId":12241,"journal":{"name":"Experimental and Clinical Endocrinology & Diabetes","volume":"131 1-02","pages":"33-50"},"PeriodicalIF":1.8,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9482047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diabetes Mellitus at an Elderly Age.","authors":"Andrej Zeyfang, Jürgen Wernecke, Anke Bahrmann","doi":"10.1055/a-1946-3728","DOIUrl":"https://doi.org/10.1055/a-1946-3728","url":null,"abstract":"recommendation 1: Modification of the use of GLP-1 agonists and SGLT-2 inhibitors in the elderly reason: NVL Type 2 DM supporting reference: REWIND, LEADER, SUSTAIN-6, EXSCEL, ELIXA, EMPE-REG, DAPA-HF recommendation 2: Participatory decision-making, individualized therapy reason: NVL Type 2 DM supporting reference: [5] recommendation 3: HbA1c target corridor reason: NVL Type 2 DM supporting reference: [5] recommendation 4: References Due to the good medical care in Germany, many people with diabetes mellitus now reach old age: Of the 340,000 adults with type 1 diabetes, more than 100,000 are over 70 years of age. Approximately 8 million people have type 2 diabetes and one-fourth of this group is over 75 years of age, and approximately 1 million over the age of 80 [1]. Nationwide, there are a total of about 630,000 people with diabetes mellitus in need of care. The statements in the practice recommendations are mainly directed at the majority of elderly people with type 2 diabetes and can only reflect some of the special characteristics of elderly people with diabetes. Topics such as type 1 diabetes at an elderly age, end of life, interface management or ethics are covered in the complete S2k guideline. The geriatric patient is defined by multimorbidity and a higher age. Age-typical functional limitations and high vulnerability create a special need for action that goes beyond blood glucose control and the management of cardiovascular risk factors or diabetes-typical complications. For differentiated therapy planning, elderly patients should be divided into functional groups (▶tab. 1). A geriatric assessment should be conducted to determine resources and deficits (division into functional groups) (Practice Tool 1, see Appendix).","PeriodicalId":12241,"journal":{"name":"Experimental and Clinical Endocrinology & Diabetes","volume":"131 1-02","pages":"24-32"},"PeriodicalIF":1.8,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9482045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katrin Esefeld, Stephan Kress, Meinolf Behrens, Peter Zimmer, Michael Stumvoll, Ulrike Thurm, Bernhard Gehr, Martin Halle, Christian Brinkmann
{"title":"Diabetes, Sports and Exercise.","authors":"Katrin Esefeld, Stephan Kress, Meinolf Behrens, Peter Zimmer, Michael Stumvoll, Ulrike Thurm, Bernhard Gehr, Martin Halle, Christian Brinkmann","doi":"10.1055/a-1946-3768","DOIUrl":"https://doi.org/10.1055/a-1946-3768","url":null,"abstract":"Affiliations 1 Department of Preventive Sports Medicine, Klinikum rechts der Isar, Technical University Munich, Munich, Germany 2 German Center for Cardiovascular Research (Deutsches Zentrum für Herzkreislaufforschung – DZHK), partner site Munich Heart Alliance (MHA), Munich, Germany 3 Diabetes, Sport and Physical Activity Working Group of the DDG 4 Department of Internal Medicine I, Vinzentius Hospital Landau, Landau, Germany 5 Diabetes Center Minden, Minden, Germany 6 Department of Internal Medicine III, University Hospital Leipzig, Leipzig, Germany 7 m&i specialized clinic Bad Heilbrunn, Bad Heilbrunn, Germany 8 Institute of Cardiovascular Research and Sport Medicine, German Sport University Cologne, Cologne, Germany 9 IST University of Applied Sciences Düsseldorf, Düsseldorf, Germany","PeriodicalId":12241,"journal":{"name":"Experimental and Clinical Endocrinology & Diabetes","volume":"131 1-02","pages":"51-60"},"PeriodicalIF":1.8,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9482046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}