{"title":"Cervical ripening with self administered iso sorbide mononitrate vaginally, in uncomplicated singleton pregnancies at 39 weeks gestation: a double blind randomised controlled trial","authors":"K. Attanayake, M. Goonewardene","doi":"10.4038/cmj.v61i4.8378","DOIUrl":"https://doi.org/10.4038/cmj.v61i4.8378","url":null,"abstract":"Introduction\u0000Vaginal iso sorbide mononitrate (ISMN) is effective in pre induction cervical ripening in post dated pregnancies.\u0000\u0000\u0000Objectives\u0000To determine the effectiveness and acceptability of ISMN self-administered vaginally at home, in causing cervical ripening in uncomplicated singleton pregnancies at 39 weeks gestation.\u0000\u0000\u0000Methods\u0000Consecutive women with uncomplicated singleton pregnancies, presenting between 01 October 2013 and 31 March 2014, with a modified Bishop score (MBS) of < 5 at a gestational age (GA) of 273 days to the University Obstetric Unit of Teaching Hospital Mahamodera Galle, were allocated by stratified (primip/multip) block randomisation to self-administer vaginally at home every other day, five doses of 60 mg of sustained release form of ISMN (ISMN-SR); (n = 72, cases), or pyridoxine 10 mgs (n=72, controls), from GA 273 to 282 days.\u0000\u0000\u0000Results\u0000The mean MBS and the mean change of MBS at 282 days, and the proportions with spontaneous onset of labour (SOL) by GA 282 days, were not significantly different between the two groups. A vast majority were satisfied with outpatient therapy (80% cases vs.76% controls), were happy to use it in a subsequent preg-nancy (89% cases vs. 86% controls) and would recom-mend it to a friend (93% cases vs. 90% controls).\u0000\u0000\u0000Conclusions\u0000Home adminstrated vaginal ISMN therapy from GA 39 weeks was not effective in causing significant cervical ripening or promoting SOL, but it was acceptable to women.","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128301263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of gestational diabetes mellitus in a Suburban District in Sri Lanka: a population based study","authors":"B. Sudasinghe, P S Ginige, C N Wijeyaratne","doi":"10.4038/cmj.v61i4.8379","DOIUrl":"https://doi.org/10.4038/cmj.v61i4.8379","url":null,"abstract":"Introduction\u0000GDM is a leading metabolic cause of morbidity to mother and offspring. Determining its prevalence is important for health planning and implementation.\u0000\u0000\u0000Objective\u0000Assess prevalence of GDM in the District of Gampaha.\u0000\u0000\u0000Method\u0000Community based cross-sectional study was conducted in women attending field-based ante-natal clinics in two Medical Officer of Health (MOH) areas between January 2014 to March 2015. Consecutive women were recruited by cluster sampling with probability proportionate to size using strict exclusion criteria. GDM diagnosis was based on fasting 75 g OGTT, WHO 1999. All responders underwent 2 hr PPBS in first trimester- >200 mg/dl with symptoms identified as abnormal, probably diabetes in pregnancy (DIP); those >120 and <200 mg/dl proceeded to OGTT before 16 weeks POA; all negatives were tested by OGTT between 24-28 weeks. Negatives for GDM at 24-28 weeks underwent OGTT between 32-36 weeks; venous plasma glucose tested by accredited laboratory.\u0000\u0000\u0000Results\u0000Sample consistedof 160, non-response 4.2% (67); 1533 underwent 2 hr PPBS with 40 exceeding 120mg: 4 >200 mg diagnosed as GDM / DIP, 36 (PPBS >120 < 200 mg) underwent OGTT before 16 weeks with 15 GDM. One hundred and thirty four (8.38%) miscarried including one with early abnormal OGTT. Of 1381 eligible for OGTT (24- 28 weeks) 150 had GDM (10.86%). Only 344 (27.94% of normal 1231) consented for third trimester OGTT, of whom 25 had GDM- yielding a total of 194 with GDM (13.9%).\u0000\u0000\u0000Conclusions\u0000The current community prevalence of GDM in the suburban Gampaha District, Sri Lanka is high.","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"139 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127458693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pathological characteristics of fifty patients with renal amyloidosis in Sri Lanka","authors":"D L P Dasanayaka, S. Wijetunge, N. Ratnatunga","doi":"10.4038/cmj.v61i4.8388","DOIUrl":"https://doi.org/10.4038/cmj.v61i4.8388","url":null,"abstract":"Renal involvement is the most important cause of morbidity and mortality in systemic amyloidosis. This retrospective analysis was conducted to analyse the clinico-pathological characteristics of renal amyloidosis in a group of Sri Lankan patients undergoing renal biopsy. Renal amyloidosis was observed in 50/ 9712 (0.5%) renal biopsies. The underlying cause for amyloidosis was not known in most. Of the known causes multiple myeloma was the commonest. Nephrotic range proteinuria was the most common clinical outcome and most had grade I to III chronic kidney disease at the time of diagnosis. Glomerulosclerosis was associated with the deterioration of renal function.","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"61 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130286231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Inguinal ureteral hernia","authors":"B. Sayanthan, G. Rathnasiri, A. Silva","doi":"10.4038/cmj.v61i4.8396","DOIUrl":"https://doi.org/10.4038/cmj.v61i4.8396","url":null,"abstract":"A 63-year-old previously healthy male was admitted with a large reducible left inguinal hernia. He was otherwise asymptomatic. The routine preoperative investigations including renal functions were normal. A routine hernia repair was conducted under spinal anaesthesia. Intra-operatively we found a para-peritoneal sliding type hernia of left ureter which was injured during hernia sac dissection. We inserted a double J stent into the injured left ureter and completed the hernia repair. Recovery was uneventful with normal urine output and renal function during post-operative period. Postoperative X-Ray KUB (Figure 1) and CT-IVU were normal. Urinary stent was removed after 6 weeks and he recovered without any complication.","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126857408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gender differences in suicide in Sri Lanka – what does it tell us?","authors":"Thilini Rajapakse, Sampath Tennakoon","doi":"10.4038/cmj.v61i4.8377","DOIUrl":"https://doi.org/10.4038/cmj.v61i4.8377","url":null,"abstract":"Rikaz Sheriff MBBS MSc Worldwide suicide is more common among males than females [1]. The male to female ratio of suicide among young adults in the United States is as high as 5:1 [1]. In contrast, attempted suicide is more common among females [1, 2]. This is sometimes referred to as the ‘gender paradox’ of suicide and self-harm behaviour [1]. Different theories have been put forward to explain the higher suicide rate among males. These include the finding that worldwide, males tend to use more lethal methods for suicide compared to females; as well as the role of cultural perceptions and gender stereotypes in suicide and self-harm behaviour [1].","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134600848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Warnasekara, S B Agampodi, P. Marage, A A S D Athurupana, S. D. Koonthota, N. Dahanayaka
{"title":"Real time surveillance of dengue fever – a preliminary study","authors":"Y. Warnasekara, S B Agampodi, P. Marage, A A S D Athurupana, S. D. Koonthota, N. Dahanayaka","doi":"10.4038/cmj.v61i4.8393","DOIUrl":"https://doi.org/10.4038/cmj.v61i4.8393","url":null,"abstract":"","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114143859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rice variety and processing: contribution to glycaemic response","authors":"T. U. Nisanka, S. Ekanayake","doi":"10.4038/cmj.v61i4.8381","DOIUrl":"https://doi.org/10.4038/cmj.v61i4.8381","url":null,"abstract":"Introduction\u0000Glycaemic index (GI) of different varieties of rice (Oryza sativa L.) commonly consumed in Sri Lanka are not widely studied even though it is the staple food.\u0000\u0000\u0000Objectives\u0000To determine the proximate compositions and the GI of three different rice meals, namely Bg 360 Samba (raw), Basmati At 405 (raw) and parboiled Nadu Bg 352.\u0000\u0000\u0000Methods\u0000The study was a randomised cross over study using healthy volunteers (n=11). GI was determined as the ratio between the incremental areas under curve obtained for the test food and the standard glucose (WHO/FAO method). Proximate compositions were determined by standard methods.\u0000\u0000\u0000Results\u0000The GI value so obtained were, 66±8 (medium GI) for Bg 360 Samba, 73±7 (high GI) for Basmati At 405 and 40±4 (low GI) for Nadu Bg 352. Parboiled variety had a significantly low GI and the lowest peak glucose concentration. Significant differences were observed in insoluble dietary fibre (IDF), total dietary fibre (TDF) and moisture contents of the rice varieties. Non significant negative correlations between IDF (r = -0.94, p = >0.05, n = 3) and TDF (r = - 0.90, p = >0.05, n = 3) and GI of the rice varieties were observed.\u0000\u0000\u0000Conclusions\u0000Parboiled Nadu Bg 352 and Bg 360 Samba (raw) are of nutritional significance to individuals seeking to control the energy intake and glycaemic response.","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126533777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Scientific research-based evidence used in drug promotion material distributed in Sri Lanka","authors":"M. Kommalage, D. Nayanarasie, S. Basnayake","doi":"10.4038/cmj.v61i4.8394","DOIUrl":"https://doi.org/10.4038/cmj.v61i4.8394","url":null,"abstract":"In the drug promotion process, pharmaceutical companies make many claims about the efficacy, safety and ‘quality’ of the products. These claims should be clear, valid and justifiable. In scientific literature, each claim should be supported by evidence. Therefore, they are expected to provide evidence to support the claims made in DPM. The high quality references increase the authenti-city of the evidence. The aim of this study was to examine the quality of scientific supportive evidence used in DPM in Sri Lanka.","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"61 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129741618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. B. Piyasiri, S. Wickramasinghe, V. C. Lekamvasam, E. Corea, R. Gunarathne, U. Priyadarshana
{"title":"Endocarditis in melioidosis","authors":"L. B. Piyasiri, S. Wickramasinghe, V. C. Lekamvasam, E. Corea, R. Gunarathne, U. Priyadarshana","doi":"10.4038/cmj.v61i4.8390","DOIUrl":"https://doi.org/10.4038/cmj.v61i4.8390","url":null,"abstract":"On examination he was emaciated, pale, looked ill and was mildly dyspnoeic. He had a high volume pulse of 72/bpm, a pan-systolic murmur in the mitral area with a loud pulmonary component of the second heart sound and bilateral basal crackles and rhonchi. Investigations showed a total white cell count of 27.8×109/l with neutrophilia (90%), a platelet count of 208×109/l, haemoglobin 9.2g/dl, CRP 49g/l, ESR 43mm/1st hour and normal blood sugar, renal and liver profiles. Blood picture revealed normochromic normocytic anaemia. His chest radiograph showed hyper-inflated lung fields with patchy consolidation. Ultrasound examination of the abdomen was normal. A provisional diagnosis of com-munity acquired pneumonia complicating COPD was made and the patient was started on intravenous cefotaxime and clarithromycin after taking blood and sputum for culture.","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"278 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115830409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Estimation of provider cost and the out of pocket expenditure for cataract surgery at a base hospital","authors":"C. Perera, D. De Silva, L. Perera","doi":"10.4038/cmj.v61i4.8395","DOIUrl":"https://doi.org/10.4038/cmj.v61i4.8395","url":null,"abstract":"A descriptive cross sectional study was conducted after obtaining approval from Ethics Review Committee, Faculty of Medicine, Ragama. Permission was obtained from the consultant ophthalmologist of the unit. A pretested interviewer administered questionnaire was used to collect data. The study was carried out from April 2015 to June 2015. All patients (n=202) who were admitted for surgery during the study period were included in the study.","PeriodicalId":122256,"journal":{"name":"The Ceylon medical journal","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116767155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}