European urology最新文献

{"title":"Re: Alexander B.C.D. Ng, Aqua Asif, Ridhi Agarwal, et al. Biparametric vs Multiparametric MRI for Prostate Cancer Diagnosis: The PRIME Diagnostic Clinical Trial. JAMA 2025;334:1170–9","authors":"Derya Tilki , Ming-Hui Chen , Anthony V. D’Amico","doi":"10.1016/j.eururo.2025.10.025","DOIUrl":"10.1016/j.eururo.2025.10.025","url":null,"abstract":"","PeriodicalId":12223,"journal":{"name":"European urology","volume":"89 5","pages":"Page e123"},"PeriodicalIF":25.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145731942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Primary Retroperitoneal Lymph Node Dissection in Marker Positive Clinical Stage II Non-Seminomatous Germ Cell Tumours","authors":"Benjamin Baker, Sarah Azari, Margaret Meagher, Giacomo Musso, Fred Millard, Aditya Bagrodia","doi":"10.1016/j.eururo.2026.01.003","DOIUrl":"10.1016/j.eururo.2026.01.003","url":null,"abstract":"","PeriodicalId":12223,"journal":{"name":"European urology","volume":"89 5","pages":"Pages 474-475"},"PeriodicalIF":25.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145961674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Discovery of Prostate-specific Membrane Antigen Ligands: The Long Road to Changes in Clinical Practice for Prostate Cancer","authors":"Martina Benešová-Schäfer , Uwe Haberkorn , John W. Babich","doi":"10.1016/j.eururo.2026.01.002","DOIUrl":"10.1016/j.eururo.2026.01.002","url":null,"abstract":"","PeriodicalId":12223,"journal":{"name":"European urology","volume":"89 5","pages":"Pages 394-395"},"PeriodicalIF":25.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145992397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Bhaskar K. Somani, Jens Rassweiler, Evangelos Liatsikos, et al. European Association of Urology Policy on Telesurgery. Eur Urol 2025;88:318–24","authors":"Marcio Covas Moschovas , Mischa Dohler , Mohamad Omar Al Kalaa , Vipul Patel","doi":"10.1016/j.eururo.2025.10.021","DOIUrl":"10.1016/j.eururo.2025.10.021","url":null,"abstract":"","PeriodicalId":12223,"journal":{"name":"European urology","volume":"89 5","pages":"Pages e118-e119"},"PeriodicalIF":25.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145731940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congress Calendar","authors":"","doi":"10.1016/j.eururo.2026.03.035","DOIUrl":"10.1016/j.eururo.2026.03.035","url":null,"abstract":"","PeriodicalId":12223,"journal":{"name":"European urology","volume":"89 5","pages":"Pages e127-e128"},"PeriodicalIF":25.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147826755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Platinum Hall of Fame","authors":"","doi":"10.1016/j.eururo.2026.03.034","DOIUrl":"10.1016/j.eururo.2026.03.034","url":null,"abstract":"","PeriodicalId":12223,"journal":{"name":"European urology","volume":"89 5","pages":"Pages e105-e116"},"PeriodicalIF":25.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147826795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and International Evaluation of an Artificial Intelligence–based Model (PROGRxN-BCa) Using the World Health Organization 2004/2022 Grading System to Predict Progression Risk and Improve Substratification for Non–muscle-invasive Bladder Cancer","authors":"Jethro C.C. Kwong ,&nbsp;Zizo Al-Daqqaq ,&nbsp;Yashan Chelliahpillai ,&nbsp;Soomin Lee ,&nbsp;Kellie Kim ,&nbsp;Maximiliano Ringa ,&nbsp;Andrew Feifer ,&nbsp;Katherine Lajkosz ,&nbsp;Marian S. Wettstein ,&nbsp;Amy Chan ,&nbsp;Taeweon Lee ,&nbsp;Myky Nguyen ,&nbsp;Wassim Kassouf ,&nbsp;Peter C. Black ,&nbsp;Rodney H. Breau ,&nbsp;Michele Lodde ,&nbsp;Adrian Fairey ,&nbsp;Jean-Baptiste Lattouf ,&nbsp;Claudio Jeldres ,&nbsp;Ricardo Rendon ,&nbsp;Girish S. Kulkarni","doi":"10.1016/j.eururo.2025.09.4145","DOIUrl":"10.1016/j.eururo.2025.09.4145","url":null,"abstract":"<div><h3>Background and objective</h3><div>Current non–muscle-invasive bladder cancer (NMIBC) tools perform suboptimally in predicting progression risk to potentially lethal muscle-invasive disease. We aimed to improve risk assessment using artificial intelligence approaches (PROGression Risk assessment in NMIBC [PROGRxN-BCa]).</div></div><div><h3>Methods</h3><div>PROGRxN-BCa was trained using 14 clinicopathological features on 3324 NMIBC patients treated from 2005 to 2022 at four Canadian institutions. External testing was performed on 9335 patients treated from 2005 to 2023 across 30 North American and European institutions. The primary outcome was time to progression (muscle-invasive or metastatic disease). PROGRxN-BCa was compared with the European Association of Urology (EAU) risk calculator. Performance was characterised using concordance index (c-index), calibration plots, instability assessments, decision curve analysis, and an algorithmic audit.</div></div><div><h3>Key findings and limitations</h3><div>During a median follow-up of 3.3 yr (interquartile range 1.6–5.8), 1405 of 12659 patients progressed. In the external testing cohort, PROGRxN-BCa had significantly higher c-index (0.79, 95% confidence interval [CI] 0.77–0.80) and net benefit overall and across different subgroups compared with the EAU risk calculator (0.71, 95% CI 0.70–0.73, <em>p</em> &lt; 0.001). This improvement was consistent regardless of treatment with bacillus Calmette-Guérin, adherence to guideline-concordant care, and World Health Organization 1973 or 2004/2022 grading system, and was consistent among patients with at least 5 yr of follow-up. It also outperformed other guideline-endorsed tools and a previously published artificial intelligence model. Compared with guideline recommendations, PROGRxN-BCa improved substratification of intermediate-risk patients into distinct risk tertiles, with estimated 5-yr progression risks of 2%, 7%, and 15%—the latter in line with high-risk NMIBC.</div></div><div><h3>Conclusions and clinical implications</h3><div>PROGRxN-BCa outperformed current tools in the largest NMIBC cohort of its kind. Its integration into guidelines could improve risk stratification and patient management.</div></div>","PeriodicalId":12223,"journal":{"name":"European urology","volume":"89 5","pages":"Pages 404-413"},"PeriodicalIF":25.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145241424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Open Versus Robotic-assisted Partial Nephrectomy in Patients with Intermediate/High-complexity Kidney Tumours: Final Results of the Randomised, Controlled, Open-label, Multicentre Trial OpeRa","authors":"Daniele Amparore ,&nbsp;Eduard Roussel ,&nbsp;Riccardo Campi ,&nbsp;Young Academic Urologists Renal Cell Carcinoma Working Group","doi":"10.1016/j.eururo.2026.01.001","DOIUrl":"10.1016/j.eururo.2026.01.001","url":null,"abstract":"","PeriodicalId":12223,"journal":{"name":"European urology","volume":"89 5","pages":"Pages 473-474"},"PeriodicalIF":25.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145962449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Targeting of HIF2-driven Cachexia in Kidney Cancer","authors":"Donghao Lyu ,&nbsp;Yifan Liu ,&nbsp;Bingnan Lu ,&nbsp;Yuntao Yao ,&nbsp;Yuanan Li,&nbsp;Hangbiao Zhang,&nbsp;Xingang Cui,&nbsp;Xiuwu Pan","doi":"10.1016/j.eururo.2026.01.018","DOIUrl":"10.1016/j.eururo.2026.01.018","url":null,"abstract":"","PeriodicalId":12223,"journal":{"name":"European urology","volume":"89 5","pages":"Pages 477-478"},"PeriodicalIF":25.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146116166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Matthew Lee, Michael Lesgart, Connor McPartland, Randall Lee, Daniel D. Eun. Robotic Transvesical Bladder Neck Reconstruction: A Novel Approach to Managing Vesicourethral Anastomotic Stenosis. Eur Urol. 2025;88:519–24","authors":"Nikita Bhatt ,&nbsp;Benoit Peyronnet ,&nbsp;Lee Zhao","doi":"10.1016/j.eururo.2025.10.024","DOIUrl":"10.1016/j.eururo.2025.10.024","url":null,"abstract":"","PeriodicalId":12223,"journal":{"name":"European urology","volume":"89 5","pages":"Pages e124-e125"},"PeriodicalIF":25.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145759428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}