{"title":"3195 – FISH IN COMBINATION WITH RT-PCR AIDS IN THE CLASSIFICATION OF B-OTHER ALL BY IMPROVING THE IDENTIFICATION OF THE ZNF384 REARRANGEMENT","authors":"Ying Wang, Qinlu Li, Shugang Xing, Heng Zhang","doi":"10.1016/j.exphem.2024.104515","DOIUrl":"https://doi.org/10.1016/j.exphem.2024.104515","url":null,"abstract":"","PeriodicalId":12202,"journal":{"name":"Experimental hematology","volume":"14 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142197268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Floriane Tissot, George Adams, Flora Birch, Sara Gonzalez-Anton, Federica Bruno, Cera Mai, Cristina Lo Celso
{"title":"3220 – THE BONE MARROW EXTRACELLULAR MATRIX REMODELLING DURING ACUTE MYELOID LEUKAEMIA","authors":"Floriane Tissot, George Adams, Flora Birch, Sara Gonzalez-Anton, Federica Bruno, Cera Mai, Cristina Lo Celso","doi":"10.1016/j.exphem.2024.104540","DOIUrl":"https://doi.org/10.1016/j.exphem.2024.104540","url":null,"abstract":"","PeriodicalId":12202,"journal":{"name":"Experimental hematology","volume":"17 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142197245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"3212 – MEGAKARYOCYTES SENSE INFECTION AND PRIME ADJACENT HEMATOPOIETIC STEM CELLS FOR INFLAMMATION","authors":"Yang Zhang, Timm Schroeder","doi":"10.1016/j.exphem.2024.104532","DOIUrl":"https://doi.org/10.1016/j.exphem.2024.104532","url":null,"abstract":"","PeriodicalId":12202,"journal":{"name":"Experimental hematology","volume":"96 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142197253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiaoqin Zhu, Sean Walulik, Sarai Dean, Andrew Volk
{"title":"3215 – TWO NOVEL ENHANCERS OF CDKN1A ARE EPIGENETICALLY REGULATED BY THE CHROMATIN ASSEMBLY FACTOR 1 AND CEBPA IN ACUTE MYELOID LEUKEMIA","authors":"Xiaoqin Zhu, Sean Walulik, Sarai Dean, Andrew Volk","doi":"10.1016/j.exphem.2024.104535","DOIUrl":"https://doi.org/10.1016/j.exphem.2024.104535","url":null,"abstract":"","PeriodicalId":12202,"journal":{"name":"Experimental hematology","volume":"6 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142197250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stephanie Xie, Murtaza Nagree, Andy Zeng, Angelica Varesi, Sayyam Shah, MIchael Zhang, Isabel Lim, Hyerin Kim, Liqing Jin, Mason Boulanger, John Dick
{"title":"3204 – CD83 MARKS ACUTE INFLAMMATORY STRESS ACTIVATION IN HUMAN HEMATOPOIETIC STEM CELLS AND ITS DEPLETION RESTRAINS INFLAMMATION RESPONSE","authors":"Stephanie Xie, Murtaza Nagree, Andy Zeng, Angelica Varesi, Sayyam Shah, MIchael Zhang, Isabel Lim, Hyerin Kim, Liqing Jin, Mason Boulanger, John Dick","doi":"10.1016/j.exphem.2024.104524","DOIUrl":"https://doi.org/10.1016/j.exphem.2024.104524","url":null,"abstract":"","PeriodicalId":12202,"journal":{"name":"Experimental hematology","volume":"27 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142197262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carl Walkley, Jacki Heraud-Farlow, Maddison Stewart, Monique Smeets, David Izon, Scott Taylor, Zhen Liang, Alistair Chalk, Ankita Goradia, Shi-Bin Hu, Jin Billy Li, Louise Purton
{"title":"3192 – ADAR1P150 PROTEIN, INDEPENDENT OF ITS A-TO-I RNA EDITING ACTIVITY, REGULATES PERIPHERAL T CELL HOMEOSTASIS AND HSC REPOPULATING CAPACITY","authors":"Carl Walkley, Jacki Heraud-Farlow, Maddison Stewart, Monique Smeets, David Izon, Scott Taylor, Zhen Liang, Alistair Chalk, Ankita Goradia, Shi-Bin Hu, Jin Billy Li, Louise Purton","doi":"10.1016/j.exphem.2024.104512","DOIUrl":"https://doi.org/10.1016/j.exphem.2024.104512","url":null,"abstract":"","PeriodicalId":12202,"journal":{"name":"Experimental hematology","volume":"11 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142197272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhen Liang , Carl R. Walkley , Jacki E. Heraud-Farlow
{"title":"A-to-I RNA editing and hematopoiesis","authors":"Zhen Liang , Carl R. Walkley , Jacki E. Heraud-Farlow","doi":"10.1016/j.exphem.2024.104621","DOIUrl":"10.1016/j.exphem.2024.104621","url":null,"abstract":"<div><p>Adenosine-to-inosine (A-to-I) RNA editing plays essential roles in modulating normal development and homeostasis. This process is catalyzed by adenosine deaminase acting on RNA (ADAR) family proteins. The most well-understood biological processes modulated by A-to-I editing are innate immunity and neurological development, attributed to ADAR1 and ADAR2, respectively. A-to-I editing by ADAR1 is also critical in regulating hematopoiesis. This review will focus on the role of A-to-I RNA editing and ADAR enzymes, particularly ADAR1, during normal hematopoiesis in humans and mice. Furthermore, we will discuss <em>Adar1</em> mouse models that have been developed to understand the contribution of ADAR1 to hematopoiesis and its role in innate immune pathways.</p></div>","PeriodicalId":12202,"journal":{"name":"Experimental hematology","volume":"139 ","pages":"Article 104621"},"PeriodicalIF":2.5,"publicationDate":"2024-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0301472X24004855/pdfft?md5=9862c030cef87f6a6067e3f78a40054e&pid=1-s2.0-S0301472X24004855-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}