FEMS microbiology reviews最新文献_第10页

Giving a signal: how protein phosphorylation helps Bacillus navigate through different life stages. 发出信号：蛋白质磷酸化如何帮助芽孢杆菌穿越不同的生命阶段。

IF 10.1 2区生物学

FEMS microbiology reviews Pub Date : 2023-07-05 DOI: 10.1093/femsre/fuad044

Aakriti Gangwal, Nishant Kumar, Nitika Sangwan, Neha Dhasmana, Uma Dhawan, Andaleeb Sajid, Gunjan Arora, Yogendra Singh

{"title":"Giving a signal: how protein phosphorylation helps Bacillus navigate through different life stages.","authors":"Aakriti Gangwal, Nishant Kumar, Nitika Sangwan, Neha Dhasmana, Uma Dhawan, Andaleeb Sajid, Gunjan Arora, Yogendra Singh","doi":"10.1093/femsre/fuad044","DOIUrl":"10.1093/femsre/fuad044","url":null,"abstract":"Protein phosphorylation is a universal mechanism regulating a wide range of cellular responses across all domains of life. The antagonistic activities of kinases and phosphatases can orchestrate the life cycle of an organism. The availability of bacterial genome sequences, particularly Bacillus species, followed by proteomics and functional studies have aided in the identification of putative protein kinases and protein phosphatases, and their downstream substrates. Several studies have established the role of phosphorylation in different physiological states of Bacillus species as they pass through various life stages such as sporulation, germination, and biofilm formation. The most common phosphorylation sites in Bacillus proteins are histidine, aspartate, tyrosine, serine, threonine, and arginine residues. Protein phosphorylation can alter protein activity, structural conformation, and protein-protein interactions, ultimately affecting the downstream pathways. In this review, we summarize the knowledge available in the field of Bacillus signaling, with a focus on the role of protein phosphorylation in its physiological processes.","PeriodicalId":12201,"journal":{"name":"FEMS microbiology reviews","volume":"47 4","pages":""},"PeriodicalIF":10.1,"publicationDate":"2023-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10465088/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10227727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Drivers and consequences of bacteriophage host range. 噬菌体宿主的驱动因素和后果范围。

IF 11.3 2区生物学

FEMS microbiology reviews Pub Date : 2023-07-05 DOI: 10.1093/femsre/fuad038

D Holtappels, Poliane Alfenas-Zerbini, B Koskella

{"title":"Drivers and consequences of bacteriophage host range.","authors":"D Holtappels, Poliane Alfenas-Zerbini, B Koskella","doi":"10.1093/femsre/fuad038","DOIUrl":"https://doi.org/10.1093/femsre/fuad038","url":null,"abstract":"Bacteriophages are obligate parasites of bacteria characterized by the breadth of hosts that they can infect. This \"host range\" depends on the genotypes and morphologies of the phage and the bacterial host, but also on the environment in which they are interacting. Understanding phage host range is critical to predicting the impacts of these parasites in their natural host communities and their utility as therapeutic agents, but is also key to predicting how phages evolve and in doing so drive evolutionary change in their host populations, including through movement of genes among unrelated bacterial genomes. Here, we explore the drivers of phage infection and host range from the molecular underpinnings of the phage-host interaction to the ecological context in which they occur. We further evaluate the importance of intrinsic, transient, and environmental drivers shaping phage infection and replication, and discuss how each influences host range over evolutionary time. The host range of phages has great consequences in phage-based application strategies, as well as natural community dynamics, and we therefore highlight both recent developments and key open questions in the field as phage-based therapeutics come back into focus.","PeriodicalId":12201,"journal":{"name":"FEMS microbiology reviews","volume":"47 4","pages":""},"PeriodicalIF":11.3,"publicationDate":"2023-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10232439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Bacteriophage-host interactions in Streptococcus thermophilus and their impact on co-evolutionary processes. 嗜热链球菌中噬菌体-宿主相互作用及其对共同进化过程的影响。

IF 11.3 2区生物学

FEMS microbiology reviews Pub Date : 2023-07-05 DOI: 10.1093/femsre/fuad032

Katherine Lavelle, Brian McDonnell, Gerald Fitzgerald, Douwe van Sinderen, Jennifer Mahony

引用次数: 1

The never-ending battle between lactic acid bacteria and their phages. 乳酸菌和噬菌体之间永无休止的战斗。

IF 11.3 2区生物学

FEMS microbiology reviews Pub Date : 2023-07-05 DOI: 10.1093/femsre/fuad035

Cécile Philippe, Jeffrey K Cornuault, Alessandra G de Melo, Rachel Morin-Pelchat, Alice P Jolicoeur, Sylvain Moineau

引用次数: 1

Anti-infective activities of long-chain fatty acids against foodborne pathogens. 长链脂肪酸对食源性致病菌的抗感染活性。

IF 11.3 2区生物学

FEMS microbiology reviews Pub Date : 2023-07-05 DOI: 10.1093/femsre/fuad037

Caroline Borreby, Eva Maria Sternkopf Lillebæk, Birgitte H Kallipolitis

引用次数: 0

Crosstalk between gut microbiota and RNA N6-methyladenosine modification in cancer. 癌症中肠道微生物群与RNA n6 -甲基腺苷修饰之间的串扰。

IF 11.3 2区生物学

FEMS microbiology reviews Pub Date : 2023-07-05 DOI: 10.1093/femsre/fuad036

Hao Su, Henley Cheung, Harry Cheuk-Hay Lau, Hongyan Chen, Xiaoting Zhang, Na Qin, Yifei Wang, Matthew Tak Vai Chan, William Ka Kei Wu, Huarong Chen

引用次数: 0

Quorum sensing architecture network in Escherichia coli virulence and pathogenesis. 群体感应结构网络在大肠杆菌毒力和发病机制中的作用。

IF 11.3 2区生物学

FEMS microbiology reviews Pub Date : 2023-07-05 DOI: 10.1093/femsre/fuad031

Celia Mayer, Anabela Borges, Saskia-Camille Flament-Simon, Manuel Simões

{"title":"Quorum sensing architecture network in Escherichia coli virulence and pathogenesis.","authors":"Celia Mayer, Anabela Borges, Saskia-Camille Flament-Simon, Manuel Simões","doi":"10.1093/femsre/fuad031","DOIUrl":"https://doi.org/10.1093/femsre/fuad031","url":null,"abstract":"Escherichia coli is a Gram-negative commensal bacterium of the normal microbiota of humans and animals. However, several E. coli strains are opportunistic pathogens responsible for severe bacterial infections, including gastrointestinal and urinary tract infections. Due to the emergence of multidrug-resistant serotypes that can cause a wide spectrum of diseases, E. coli is considered one of the most troublesome human pathogens worldwide. Therefore, a more thorough understanding of its virulence control mechanisms is essential for the development of new anti-pathogenic strategies. Numerous bacteria rely on a cell density-dependent communication system known as quorum sensing (QS) to regulate several bacterial functions, including the expression of virulence factors. The QS systems described for E. coli include the orphan SdiA regulator, an autoinducer-2 (AI-2), an autoinducer-3 (AI-3) system, and indole, which allow E. coli to establish different communication processes to sense and respond to the surrounding environment. This review aims to summarise the current knowledge of the global QS network in E. coli and its influence on virulence and pathogenesis. This understanding will help to improve anti-virulence strategies with the E. coli QS network in focus.","PeriodicalId":12201,"journal":{"name":"FEMS microbiology reviews","volume":"47 4","pages":""},"PeriodicalIF":11.3,"publicationDate":"2023-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9800219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Correction to: four billion years of microbial terpenome evolution. 修正为:40亿年的微生物萜烯素进化。

IF 11.3 2区生物学

FEMS microbiology reviews Pub Date : 2023-07-05 DOI: 10.1093/femsre/fuad027

引用次数: 0

Editorial 14th international symposium on lactic acid bacteria (LAB14). 第十四届乳酸菌国际学术研讨会(LAB14)。

IF 11.3 2区生物学

FEMS microbiology reviews Pub Date : 2023-07-05 DOI: 10.1093/femsre/fuad043

Eddy J Smid, Sarah Lebeer, Egon B Hansen

引用次数: 0

From genotype to phenotype: computational approaches for inferring microbial traits relevant to the food industry. 从基因型到表型：推断与食品工业相关的微生物特征的计算方法。

IF 11.3 2区生物学

FEMS microbiology reviews Pub Date : 2023-07-05 DOI: 10.1093/femsre/fuad030

Signe T Karlsen, Martin H Rau, Benjamín J Sánchez, Kristian Jensen, Ahmad A Zeidan

{"title":"From genotype to phenotype: computational approaches for inferring microbial traits relevant to the food industry.","authors":"Signe T Karlsen, Martin H Rau, Benjamín J Sánchez, Kristian Jensen, Ahmad A Zeidan","doi":"10.1093/femsre/fuad030","DOIUrl":"10.1093/femsre/fuad030","url":null,"abstract":"When selecting microbial strains for the production of fermented foods, various microbial phenotypes need to be taken into account to achieve target product characteristics, such as biosafety, flavor, texture, and health-promoting effects. Through continuous advances in sequencing technologies, microbial whole-genome sequences of increasing quality can now be obtained both cheaper and faster, which increases the relevance of genome-based characterization of microbial phenotypes. Prediction of microbial phenotypes from genome sequences makes it possible to quickly screen large strain collections in silico to identify candidates with desirable traits. Several microbial phenotypes relevant to the production of fermented foods can be predicted using knowledge-based approaches, leveraging our existing understanding of the genetic and molecular mechanisms underlying those phenotypes. In the absence of this knowledge, data-driven approaches can be applied to estimate genotype-phenotype relationships based on large experimental datasets. Here, we review computational methods that implement knowledge- and data-driven approaches for phenotype prediction, as well as methods that combine elements from both approaches. Furthermore, we provide examples of how these methods have been applied in industrial biotechnology, with special focus on the fermented food industry.","PeriodicalId":12201,"journal":{"name":"FEMS microbiology reviews","volume":"47 4","pages":""},"PeriodicalIF":11.3,"publicationDate":"2023-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/69/bd/fuad030.PMC10337747.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9799218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0