Food and cosmetics toxicology最新文献

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Chlorinated insecticides and the diet 氯化杀虫剂和饮食
Food and cosmetics toxicology Pub Date : 1981-01-01 DOI: 10.1016/0015-6264(81)90373-4
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引用次数: 0
Books received for review 接受评审的书籍
Food and cosmetics toxicology Pub Date : 1981-01-01 DOI: 10.1016/0015-6264(81)90370-9
{"title":"Books received for review","authors":"","doi":"10.1016/0015-6264(81)90370-9","DOIUrl":"https://doi.org/10.1016/0015-6264(81)90370-9","url":null,"abstract":"","PeriodicalId":12197,"journal":{"name":"Food and cosmetics toxicology","volume":"19 ","pages":"Pages 266-267"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0015-6264(81)90370-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136818929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mass spectrometry. Vol. 5. A review of the recent literature published between July 1976 and June 1978 质谱分析。卷。5。回顾1976年7月至1978年6月间发表的最新文献
Food and cosmetics toxicology Pub Date : 1981-01-01 DOI: 10.1016/0015-6264(81)90368-0
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引用次数: 0
Arsenicals and lung cancer 砷和肺癌
Food and cosmetics toxicology Pub Date : 1981-01-01 DOI: 10.1016/0015-6264(81)90332-1
{"title":"Arsenicals and lung cancer","authors":"","doi":"10.1016/0015-6264(81)90332-1","DOIUrl":"https://doi.org/10.1016/0015-6264(81)90332-1","url":null,"abstract":"","PeriodicalId":12197,"journal":{"name":"Food and cosmetics toxicology","volume":"19 ","pages":"Page 132"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0015-6264(81)90332-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136819171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developments in food colours—1 食用色素的发展——1
Food and cosmetics toxicology Pub Date : 1981-01-01 DOI: 10.1016/0015-6264(81)90312-6
{"title":"Developments in food colours—1","authors":"","doi":"10.1016/0015-6264(81)90312-6","DOIUrl":"https://doi.org/10.1016/0015-6264(81)90312-6","url":null,"abstract":"","PeriodicalId":12197,"journal":{"name":"Food and cosmetics toxicology","volume":"19 ","pages":"Page 117"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0015-6264(81)90312-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136819272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Toxicological aspects of food safety 食品安全的毒理学方面
Food and cosmetics toxicology Pub Date : 1981-01-01 DOI: 10.1016/0015-6264(81)90313-8
{"title":"Toxicological aspects of food safety","authors":"","doi":"10.1016/0015-6264(81)90313-8","DOIUrl":"https://doi.org/10.1016/0015-6264(81)90313-8","url":null,"abstract":"","PeriodicalId":12197,"journal":{"name":"Food and cosmetics toxicology","volume":"19 ","pages":"Pages 117-118"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0015-6264(81)90313-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136819273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Three-generation reproduction study of rats ingesting 2,4,5-trichlorophenoxyacetic acid in the diet 饮食中摄入2,4,5-三氯苯氧乙酸的大鼠三代繁殖研究
Food and cosmetics toxicology Pub Date : 1981-01-01 DOI: 10.1016/0015-6264(81)90301-1
F.A. Smith, F.J. Murray, J.A. John, K.D. Nitschke, R.J. Kociba, B.A. Schwetz
{"title":"Three-generation reproduction study of rats ingesting 2,4,5-trichlorophenoxyacetic acid in the diet","authors":"F.A. Smith,&nbsp;F.J. Murray,&nbsp;J.A. John,&nbsp;K.D. Nitschke,&nbsp;R.J. Kociba,&nbsp;B.A. Schwetz","doi":"10.1016/0015-6264(81)90301-1","DOIUrl":"10.1016/0015-6264(81)90301-1","url":null,"abstract":"<div><p>Male and female 4–6-wk-old Sprague-Dawley rats (F<sub>0</sub>) were fed lab chow containing 2,4,5-T to provide dosage levels of 0, 3, 10 or 30 mg/kg/day for 90 days and were then bred. At day 21 of lactation, pups were randomly selected for the following generation (F<sub>1</sub>) and the rest were autopsied. Subsequent matings were conducted to produce F<sub>2</sub>, F<sub>3a</sub> and F<sub>3b</sub> litters, successive generations being fed from weaning on the appropriate test or control diet. Fertility was decreased in the matings for the F<sub>3b</sub> litters in the group on the 10-mg/kg/day dose level. Postnatal survival was significantly decreased in the F<sub>2</sub> litters of the 10-mg/kg group and the F<sub>1′</sub> F<sub>2</sub> and F<sub>3a</sub> litters of the 30-mg/kg/day group. The relative liver weight of weanlings was significantly increased in the F<sub>2′</sub> F<sub>3a</sub> and F<sub>b</sub> litters of the 30-mg/kg/day group. A significant decrease in relative thymus weight was seen only in the F<sub>b</sub> generation of this dosage group. Thus, dose levels of 2,4,5-T that were sufficiently high to cause signs of toxicity in neonates had no effect on the reproductive capacity of rats, except for a tendency toward a reduction in postnatal survival at a dose level of 30 mg/kg/day. Reproduction was not impaired at the lowest dose level (3 mg/kg/day).</p></div>","PeriodicalId":12197,"journal":{"name":"Food and cosmetics toxicology","volume":"19 ","pages":"Pages 41-45"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0015-6264(81)90301-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18275619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Studies on the metabolism of calcium stearoyl-2-lactylate in the rat, mouse, guinea-pig and man 硬脂酰-2-乳酸钙在大鼠、小鼠、豚鼠和人体内的代谢研究
Food and cosmetics toxicology Pub Date : 1981-01-01 DOI: 10.1016/0015-6264(81)90296-0
J.C. Phillips, C. Topp, S.D. Gangolli
{"title":"Studies on the metabolism of calcium stearoyl-2-lactylate in the rat, mouse, guinea-pig and man","authors":"J.C. Phillips,&nbsp;C. Topp,&nbsp;S.D. Gangolli","doi":"10.1016/0015-6264(81)90296-0","DOIUrl":"10.1016/0015-6264(81)90296-0","url":null,"abstract":"<div><p>The absorption, metabolism, tissue distribution and excretion of <sup>14</sup>C-labelled calcium stearoyl-2-lactylate (CSL) was compared with that of [U-<sup>14</sup>C]lactic acid in the mouse and the guinea-pig. A comparison was also made of the rates of hydrolysis of CSL by various tissue preparations from the rat, mouse, guinea-pig and man. In both mice and guinea-pigs, the metabolism and tissue distribution of radioactivity from [U-<sup>14</sup>C]lactate-labelled CSL were similar to those of an equivalent dose of free [U-<sup>14</sup>C]lactate, with the majority of the radioactivity rapidly excreted as <sup>14</sup>CO<sub>2</sub>. Homogenates of liver and intestinal mucosa from the rat, mouse and guinea-pig rapidly hydrolysed CSL to lactic acid and stearic acid, and whole blood from rats and mice also hydrolysed the compound, but at a much slower rate. Although no significant hydrolysis of CSL was detected using human blood, the single sample of human duodenal mucosa rapidly hydrolysed the compound to stearic and lactic acids. These studies suggest that the biological fate of CSL is similar in all the species investigated and that the compound is unlikely to present a hazard to man in terms of its metabolic fate.</p></div>","PeriodicalId":12197,"journal":{"name":"Food and cosmetics toxicology","volume":"19 ","pages":"Pages 7-11"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0015-6264(81)90296-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18275621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Banbury Report. 1. Assessing Chemical Mutagens: The Risk to Humans 班伯里报告。评估化学诱变剂:对人类的风险
Food and cosmetics toxicology Pub Date : 1981-01-01 DOI: 10.1016/0015-6264(81)90320-5
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引用次数: 8
Dioxin: Teratogenicity and reproductive effects 二恶英:致畸性和生殖效应
Food and cosmetics toxicology Pub Date : 1981-01-01 DOI: 10.1016/0015-6264(81)90324-2
K. Miller
{"title":"Dioxin: Teratogenicity and reproductive effects","authors":"K. Miller","doi":"10.1016/0015-6264(81)90324-2","DOIUrl":"10.1016/0015-6264(81)90324-2","url":null,"abstract":"","PeriodicalId":12197,"journal":{"name":"Food and cosmetics toxicology","volume":"19 ","pages":"Pages 123-127"},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0015-6264(81)90324-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77949452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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