{"title":"Chlorinated insecticides and the diet","authors":"","doi":"10.1016/0015-6264(81)90373-4","DOIUrl":"https://doi.org/10.1016/0015-6264(81)90373-4","url":null,"abstract":"","PeriodicalId":12197,"journal":{"name":"Food and cosmetics toxicology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0015-6264(81)90373-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136818927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Books received for review","authors":"","doi":"10.1016/0015-6264(81)90370-9","DOIUrl":"https://doi.org/10.1016/0015-6264(81)90370-9","url":null,"abstract":"","PeriodicalId":12197,"journal":{"name":"Food and cosmetics toxicology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0015-6264(81)90370-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136818929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mass spectrometry. Vol. 5. A review of the recent literature published between July 1976 and June 1978","authors":"","doi":"10.1016/0015-6264(81)90368-0","DOIUrl":"https://doi.org/10.1016/0015-6264(81)90368-0","url":null,"abstract":"","PeriodicalId":12197,"journal":{"name":"Food and cosmetics toxicology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0015-6264(81)90368-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136818931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Arsenicals and lung cancer","authors":"","doi":"10.1016/0015-6264(81)90332-1","DOIUrl":"https://doi.org/10.1016/0015-6264(81)90332-1","url":null,"abstract":"","PeriodicalId":12197,"journal":{"name":"Food and cosmetics toxicology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0015-6264(81)90332-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136819171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Developments in food colours—1","authors":"","doi":"10.1016/0015-6264(81)90312-6","DOIUrl":"https://doi.org/10.1016/0015-6264(81)90312-6","url":null,"abstract":"","PeriodicalId":12197,"journal":{"name":"Food and cosmetics toxicology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0015-6264(81)90312-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136819272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Toxicological aspects of food safety","authors":"","doi":"10.1016/0015-6264(81)90313-8","DOIUrl":"https://doi.org/10.1016/0015-6264(81)90313-8","url":null,"abstract":"","PeriodicalId":12197,"journal":{"name":"Food and cosmetics toxicology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0015-6264(81)90313-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136819273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Three-generation reproduction study of rats ingesting 2,4,5-trichlorophenoxyacetic acid in the diet","authors":"F.A. Smith, F.J. Murray, J.A. John, K.D. Nitschke, R.J. Kociba, B.A. Schwetz","doi":"10.1016/0015-6264(81)90301-1","DOIUrl":"10.1016/0015-6264(81)90301-1","url":null,"abstract":"<div><p>Male and female 4–6-wk-old Sprague-Dawley rats (F<sub>0</sub>) were fed lab chow containing 2,4,5-T to provide dosage levels of 0, 3, 10 or 30 mg/kg/day for 90 days and were then bred. At day 21 of lactation, pups were randomly selected for the following generation (F<sub>1</sub>) and the rest were autopsied. Subsequent matings were conducted to produce F<sub>2</sub>, F<sub>3a</sub> and F<sub>3b</sub> litters, successive generations being fed from weaning on the appropriate test or control diet. Fertility was decreased in the matings for the F<sub>3b</sub> litters in the group on the 10-mg/kg/day dose level. Postnatal survival was significantly decreased in the F<sub>2</sub> litters of the 10-mg/kg group and the F<sub>1′</sub> F<sub>2</sub> and F<sub>3a</sub> litters of the 30-mg/kg/day group. The relative liver weight of weanlings was significantly increased in the F<sub>2′</sub> F<sub>3a</sub> and F<sub>b</sub> litters of the 30-mg/kg/day group. A significant decrease in relative thymus weight was seen only in the F<sub>b</sub> generation of this dosage group. Thus, dose levels of 2,4,5-T that were sufficiently high to cause signs of toxicity in neonates had no effect on the reproductive capacity of rats, except for a tendency toward a reduction in postnatal survival at a dose level of 30 mg/kg/day. Reproduction was not impaired at the lowest dose level (3 mg/kg/day).</p></div>","PeriodicalId":12197,"journal":{"name":"Food and cosmetics toxicology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0015-6264(81)90301-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18275619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Studies on the metabolism of calcium stearoyl-2-lactylate in the rat, mouse, guinea-pig and man","authors":"J.C. Phillips, C. Topp, S.D. Gangolli","doi":"10.1016/0015-6264(81)90296-0","DOIUrl":"10.1016/0015-6264(81)90296-0","url":null,"abstract":"<div><p>The absorption, metabolism, tissue distribution and excretion of <sup>14</sup>C-labelled calcium stearoyl-2-lactylate (CSL) was compared with that of [U-<sup>14</sup>C]lactic acid in the mouse and the guinea-pig. A comparison was also made of the rates of hydrolysis of CSL by various tissue preparations from the rat, mouse, guinea-pig and man. In both mice and guinea-pigs, the metabolism and tissue distribution of radioactivity from [U-<sup>14</sup>C]lactate-labelled CSL were similar to those of an equivalent dose of free [U-<sup>14</sup>C]lactate, with the majority of the radioactivity rapidly excreted as <sup>14</sup>CO<sub>2</sub>. Homogenates of liver and intestinal mucosa from the rat, mouse and guinea-pig rapidly hydrolysed CSL to lactic acid and stearic acid, and whole blood from rats and mice also hydrolysed the compound, but at a much slower rate. Although no significant hydrolysis of CSL was detected using human blood, the single sample of human duodenal mucosa rapidly hydrolysed the compound to stearic and lactic acids. These studies suggest that the biological fate of CSL is similar in all the species investigated and that the compound is unlikely to present a hazard to man in terms of its metabolic fate.</p></div>","PeriodicalId":12197,"journal":{"name":"Food and cosmetics toxicology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0015-6264(81)90296-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18275621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Banbury Report. 1. Assessing Chemical Mutagens: The Risk to Humans","authors":"","doi":"10.1016/0015-6264(81)90320-5","DOIUrl":"10.1016/0015-6264(81)90320-5","url":null,"abstract":"","PeriodicalId":12197,"journal":{"name":"Food and cosmetics toxicology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0015-6264(81)90320-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52927943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dioxin: Teratogenicity and reproductive effects","authors":"K. Miller","doi":"10.1016/0015-6264(81)90324-2","DOIUrl":"10.1016/0015-6264(81)90324-2","url":null,"abstract":"","PeriodicalId":12197,"journal":{"name":"Food and cosmetics toxicology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0015-6264(81)90324-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77949452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}