Facial Plastic Surgery最新文献

{"title":"First Insights on the Upcoming Role of Next-Generation PLLA-LASYNPRO in Aesthetic and Regenerative Medicine: A Survey of Experts-the PLLA-LASYNPRO Rationale.","authors":"Dario Bertossi, Maurizio Cavallini, Alessandra Camporese, Roberto Dell'Avanzato, Nicola Kefalas, Enrico Massidda, Marco Papagni, Mariagrazia Patalano, Sandro Quartucci, Monica Renga, Adriano Santorelli, Chantal Sciuto, Gloria Trocchi","doi":"10.1055/a-2764-3062","DOIUrl":"10.1055/a-2764-3062","url":null,"abstract":"<p><strong>Introduction: </strong>Injectable collagen stimulators have traditionally been linked to inflammatory foreign-body reactions (FBR) as a mechanism of action. However, the next-generation PLLA-LASYNPRO microspheres, contained in the CE-marked JULÄINE medical device, may represent a paradigm shift. Preclinical data suggest these microspheres can promote collagen and extracellular matrix (ECM) regeneration with minimal inflammatory response.</p><p><strong>Objectives and hypotheses: </strong>This study aimed to evaluate the scientific soundness and clinical relevance of a non-inflammatory mechanism of action for PLLA-LASYNPRO. The central hypothesis was that design and manufacturing innovations could enable effective biostimulation while reducing inflammation and long-term tissue reactions.</p><p><strong>Study design: </strong>A structured expert board meeting was convened to assess the rationale and implications of this emerging mechanism. The process included a preliminary survey and an in-person consensus meeting involving multidisciplinary specialists in aesthetic and regenerative medicine.</p><p><strong>Methods: </strong>On January 24, 2025, 13 experts in aesthetic medicine, dermatology, and plastic surgery participated in a board meeting held in Milan, Italy. Scientific literature and preclinical data were reviewed in advance. Discussions were organized around biophysical characteristics, tissue integration, inflammatory profile, and safety considerations.</p><p><strong>Results: </strong>The board considered the non-inflammatory mechanism of PLLA-LASYNPRO both biologically plausible and clinically promising. Key differentiating features included particle morphology, lack of excipients, and manufacturing purity. The panel highlighted the potential to reduce chronic inflammation, a known limitation of traditional collagen stimulators. Early clinical impressions supported this hypothesis, although prospective data are still forthcoming.</p><p><strong>Conclusion: </strong>This manuscript presents the consensus of a multidisciplinary board on the rationale for PLLA-LASYNPRO in aesthetic and regenerative medicine. It forms the first part of a two-paper series. The second manuscript will provide practical clinical guidance for the deep dermal administration of PLLA-LASYNPRO and real-world use of JULÄINE.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":"538-544"},"PeriodicalIF":1.5,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13364261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147316829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age-Related Changes in Nasal Septal Composition: A CT-Based Morphometric Analysis.","authors":"Mustafa Emrah Kınal, Niyazi Günsu Koç","doi":"10.1055/a-2916-4007","DOIUrl":"10.1055/a-2916-4007","url":null,"abstract":"<p><strong>Introduction: </strong>The nasal septum plays an important role in craniofacial development and rhinoplasty, but age-related changes in septal composition remain incompletely understood.</p><p><strong>Objectives & hypotheses: </strong>This study aimed to evaluate age-related morphometric changes in the nasal septum and test the hypothesis that septal composition shifts from cartilage to bone dominance with aging.</p><p><strong>Study design: </strong>Retrospective cross-sectional study (STROBE-compliant).</p><p><strong>Methods: </strong>Facial CT scans from 200 patients were analyzed. Septal cartilage area (SCA), lamina perpendicularis area (LPA), vomer area (VA), total septum area (TSA), cartilage-to-bone ratio, and SCA/LPA ratio were measured and compared by age and sex.</p><p><strong>Results: </strong>TSA increased until adolescence and remained stable thereafter. SCA declined after adolescence, whereas LPA increased until early adulthood. Cartilage dominance progressively decreased and stabilized after 30 years. Similar proportional trends were observed in both sexes.</p><p><strong>Conclusion: </strong>Nasal septum morphology undergoes a distinct age-related transition characterized by a shift from cartilage dominance to bony dominance, reaching equilibrium after early adulthood.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148469803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Use of Muscle-Hitch and Internal Gradual Tension Quilting Sutures for Eyebrow Lift Using an Open Temple Approach.","authors":"Dallan Dargan, Yangmyung Ma, Muhammad Adil Abbas Khan, Umar Daraz Khan, Muhammad Riaz","doi":"10.1055/a-2852-6977","DOIUrl":"10.1055/a-2852-6977","url":null,"abstract":"<p><strong>Introduction: </strong>Brow lift incorporates an assessment and correction of multiple factors which differ considerably between patients. Various options for brow lift exist, each with its limitations when correcting the full spectrum of age-related changes to the eyebrow.</p><p><strong>Objectives and hypotheses: </strong>To describe a brow lift technique that addresses the limitations seen in other techniques.</p><p><strong>Study design: </strong>Case series.</p><p><strong>Methods: </strong>The technique was performed from 2022 to 2023 for 70 patients aged 40 to 77 years. All patients were female.</p><p><strong>Results: </strong>All patients underwent the technique with satisfactory results and no complications. No infection of the wound or asymmetry was observed, and no patients required a revision operation. No major complications such as facial paralysis or necrosis were observed.</p><p><strong>Conclusion: </strong>This technique is a versatile procedure with good aesthetic outcomes which preserves facial animation and can be combined with other procedures while effectively elevating the lateral third of the eyebrow.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148263900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Platelet-Rich Plasma and Platelet-Rich Fibrin in Facial Plastic Surgery: A Comprehensive Literature Review.","authors":"Savan Shah, Tasnim Kamal, Daniel Ben Ner, Alwyn D'Souza, Anil Joshi","doi":"10.1055/a-2869-5904","DOIUrl":"https://doi.org/10.1055/a-2869-5904","url":null,"abstract":"<p><strong>Aim and background: </strong>To summarize current evidence on Platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) applications and outcomes in facial plastic surgery.</p><p><strong>Technology: </strong>PRP and PRF are autologous platelet concentrates with regenerative potential. They release growth factors that promote tissue repair, angiogenesis, extracellular matrix remodeling, graft integration, and scar remodeling, making them increasingly relevant in facial plastic surgery.</p><p><strong>Patient selection: </strong>A narrative review of clinical studies, meta-analyses, and systematic reviews was conducted. Key outcomes included wound healing, graft retention, postoperative edema and ecchymosis, scar improvement, and patient satisfaction.</p><p><strong>Current and future development: </strong>PRP improved wound healing, reduced crusting, and enhanced patient satisfaction in rhinoplasty, while PRF decreased cartilage resorption and improved graft stability. In rhytidectomy, PRP offered modest reductions in edema and ecchymosis. Both agents enhanced scar revision and fat graft outcomes, with PRF showing superior remodeling and long-term graft retention. In periorbital rejuvenation, PRP improved pigmentation and satisfaction, whereas PRF improved skin texture and wrinkles. Both were safe with minimal adverse events.</p><p><strong>Conclusion and clinical relevance: </strong>PRP and PRF are effective biologic adjuncts in facial plastic surgery, supporting tissue regeneration, graft integration, and aesthetic outcomes. Efficacy is influenced by patient factors and technique. High-quality, procedure-specific trials are needed to optimize protocols.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148301476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Functional Rhinoplasty on Sleep-Disordered Breathing: A Systematic Review and Meta-Analysis.","authors":"Lee Fang Ang, Nevin Yi Meng Chua, Sean Bo Jie Loh, Francesco Di Pierro, Chew Lip Ng","doi":"10.1055/a-2891-4516","DOIUrl":"https://doi.org/10.1055/a-2891-4516","url":null,"abstract":"<p><strong>Introduction: </strong>Structural nasal obstruction is an important modifier of sleep-disordered breathing (SDB), but the specific impact of functional rhinoplasty on validated sleep-related outcomes has not been quantitatively synthesized.</p><p><strong>Objective and hypothesis: </strong>To systematically review and meta-analyze studies of adults with SDB undergoing functional rhinoplasty or septorhinoplasty, testing the hypothesis that surgery yields large improvements in nasal obstruction and modest improvements in sleep-related symptoms.</p><p><strong>Study design: </strong>PROSPERO-registered systematic review and random-effects meta-analysis conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020.</p><p><strong>Methods: </strong>PubMed, Embase and Cochrane Library were searched to September 2025 for studies reporting validated symptom scores before and after functional rhinoplasty or septorhinoplasty in adults with SDB. Standardized mean differences (SMDs) with Hartung-Knapp-adjusted confidence intervals were pooled; risk of bias and publication bias were formally assessed.</p><p><strong>Results: </strong>Eight studies (27 cohorts; <i>n</i> = 1,192) met inclusion criteria. Surgery was associated with large improvement in nasal obstruction (Nasal Obstruction Symptom Evaluation SMD: -4.99; 95% CI: -9.12 to -0.85), moderate reductions in daytime sleepiness (Epworth Sleepiness Scale SMD: -1.09; 95% CI: -2.33 to 0.15) and global sleep disturbance (Pittsburgh Sleep Quality Index SMD: -0.74; 95% CI: -1.21 to -0.26), and modest gains in functional status (Functional Outcomes of Sleep Questionnaire-10 SMD: 0.41; 95% CI: 0.16-0.65). Heterogeneity was substantial for most outcomes and small-study effects were detected.</p><p><strong>Conclusion: </strong>Functional rhinoplasty and septorhinoplasty appear to improve nasal obstruction and sleep-related patient-reported outcomes in adults with SDB, supporting their role as adjunctive procedures in selected patients. High heterogeneity and predominantly observational data highlight the need for larger, phenotype-driven studies to refine effect estimates and patient selection (PROSPERO registration number: CRD420251168358).</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148276640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preservation of Nasal Valve Function in Congenital Deficiency of the Lower Lateral Cartilage: A Systematic Review and Case Series.","authors":"Mahmoud Daoud, Maria Louise Fufezan, Walid Bahaa-Eddin, Luana-Maria Gherasie, Viorel Zainea","doi":"10.1055/a-2889-9924","DOIUrl":"10.1055/a-2889-9924","url":null,"abstract":"<p><strong>Introduction: </strong>Isolated congenital lower lateral cartilage (LLC) anomalies are incidental intraoperative findings that challenge surgical planning. Despite their role in external nasal valve (ENV) support, variable clinical presentation suggests the existence of compensatory mechanisms that warrant further investigation.</p><p><strong>Objective and hypothesis: </strong>We evaluate the available evidence on isolated congenital LLC deficiency to explore reported preoperative nasal valve dysfunction and surgical outcomes, with the hypothesis that the available evidence demonstrates an association between isolated congenital LLC deficiency and nasal valve dysfunction.</p><p><strong>Study design: </strong>Preferred Reporting Items for Systematic Reviews and Meta-Analyses-compliant systematic review and case series.</p><p><strong>Methods: </strong>A systematic search of three databases was undertaken to identify reports of isolated congenital LLC deficiency. Studies without intraoperative confirmation and those involving pediatric populations were excluded. The validated Joanna Briggs Institute (JBI) Critical Appraisal Tools and Case Report Guidelines were used to assess evidence quality.</p><p><strong>Results: </strong>Fifteen studies (<i>n</i> = 18) were eligible, comprising 14 case reports and one case series. Unilateral involvement was most common (<i>n</i> = 16), with the middle crus most frequently affected. Eight patients were asymptomatic. Only three studies were rated as high quality (JBI: 6-7/8). In our case series, the incidence of isolated congenital LLC absence was 0.002, and lateral crus absence was asymptomatic, whereas absence of the medial and middle crura was associated with dynamic ENV collapse. These observations are hypothesis-generating, suggesting a greater functional role for medial crus integrity in nasal valve competence, with lateral crus absence appearing more consistently asymptomatic across the literature.</p><p><strong>Conclusion: </strong>Potential compensatory mechanisms may help preserve nasal valve function despite isolated LLC deficiency, a rare anomaly that underscores the need for intraoperative preparedness and tailored reconstruction when encountered incidentally.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148175732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"German Translation and Validation of the Standardized Cosmesis and Health Nasal Outcomes Survey Questionnaire.","authors":"Sebastian Haack, Mikhail Saltychev, Sam P Most, Michael Brandstetter, Steven Mann, Antonia Wurm, Mattia Nolli, Maximilian Mahrhofer","doi":"10.1055/a-2890-3203","DOIUrl":"10.1055/a-2890-3203","url":null,"abstract":"<p><strong>Introduction: </strong>The Standardized Cosmesis and Health Nasal Outcomes Survey (SCHNOS) is a validated patient-reported outcome measure assessing both functional and cosmetic aspects of rhinoplasty. Despite widespread use, no validated German version has been available to date.</p><p><strong>Objective and hypothesis: </strong>To translate and validate the German version of the questionnaire.</p><p><strong>Study design: </strong>Prospective case-control study.</p><p><strong>Methods: </strong>This study followed international translation guidelines including forward and backward translation, patient interviews (<i>n</i> = 10), and a validation study involving 25 rhinoplasty patients and 25 healthy controls. Internal consistency, test-retest reliability, and construct validity were evaluated.</p><p><strong>Results: </strong>The German SCHNOS demonstrated excellent internal consistency (Cronbach's α: 0.95 for SCHNOS-O, 0.94 for SCHNOS-C). Test-retest reliability was very strong. Exploratory factor analysis confirmed unidimensionality of both domains.</p><p><strong>Conclusion: </strong>The German SCHNOS is a valid and reproducible tool for evaluating rhinoplasty outcomes. It facilitates standardized assessment of functional and aesthetic results to be used in clinical practice and research within German-speaking populations.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148204740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resting Angle Correction beyond Aesthetics: A Retrospective Cohort Study Demonstrating Its Role in Nasal Valve Repair.","authors":"Mahmoud Daoud, Maria Louise Fufezan, Walid Bahaa-Eddin, Luana-Maria Gherasie, Viorel Zainea","doi":"10.1055/a-2890-3279","DOIUrl":"10.1055/a-2890-3279","url":null,"abstract":"<p><strong>Introduction: </strong>The resting angle forms between the lateral crus of the lower lateral cartilage (LLC) and the upper lateral cartilage. While conventional nasal valve repair relies on cartilage grafting for reinforcement of these structures, the functional significance of resting angle adjustment remains underexplored.</p><p><strong>Objective and hypothesis: </strong>We describe a technique to reposition the LLC, adjusting the resting angle to support the lateral nasal wall and restore external nasal valve (ENV) function without grafts, with the hypothesis that this approach improves functional and aesthetic outcomes.</p><p><strong>Study design: </strong>Retrospective cohort study.</p><p><strong>Methods: </strong>We retrospectively identified patients with ENV collapse-related nasal obstruction who underwent the described surgery. Pre- and postoperative peak nasal inspiratory flow (PNIF) measurements and FACE-Q scores were compared to evaluate functional and aesthetic improvement, respectively.</p><p><strong>Results: </strong>Thirty patients (22 female, 8 male) were included. Postoperatively, median PNIF increased from 74.0 L/minute (interquartile range [IQR]: 73.0-76.0; 95% confidence interval [CI]: 72.5-75.5) to 96.0 L/minute (IQR: 93.0-97.0; 95% CI: 94.0-97.5), and median FACE-Q Satisfaction with nose scores from 17 (IQR: 16.0-18.0; 95% CI: 16.0-17.5) to 37 (IQR: 35.0-38.0; 95% CI: 36.5-37.5); both improvements were statistically significant (<i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>Resting angle correction may not only improve aesthetics, but also stabilize the lateral nasal wall to prevent or repair ENV collapse.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148204715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified Spreader Flap Tension Suture Technique for Internal Nasal Valve Reconstruction: A 580-Patient Cohort Study.","authors":"Mahmoud Daoud, Walid Bahaa-Eddin, Maria Louise Fufezan, Luana-Maria Gherasie, Viorel Zainea","doi":"10.1055/a-2889-9842","DOIUrl":"10.1055/a-2889-9842","url":null,"abstract":"<p><strong>Introduction: </strong>The internal nasal valve (INV) is a key determinant of nasal airflow and is dependent on middle vault integrity. While spreader grafts remain the gold standard for reconstruction, the spreader flap offers a tissue-preserving alternative.</p><p><strong>Objective and hypothesis: </strong>This study evaluates outcomes of a modified spreader flap tension suture technique with composite flap elevation in 580 patients, with the hypothesis that this approach yields favorable functional improvements.</p><p><strong>Study design: </strong>Retrospective cohort study.</p><p><strong>Methods: </strong>Patients who underwent the described procedure were retrospectively identified. Inclusion required a dorsal hump reduction of >3 mm in all cases. Patients were stratified into three groups according to clinical presentation: those undergoing dorsal refinement alone, those with concurrent septal deviation or turbinate hypertrophy, and those with primary INV insufficiency. Prior dorsal rhinoplasty or significant septal deviation were exclusion criteria. Pre- and postoperative (6 months) peak nasal inspiratory flow (PNIF) measurements and visual analog scale (VAS) scores were compared to evaluate objective and subjective functional improvement, respectively.</p><p><strong>Results: </strong>The dorsal refinement group (<i>n</i> = 362) demonstrated stable functional outcomes, with a mean VAS improvement of 2 points. The septal deviation/turbinate hypertrophy group (<i>n</i> = 158) had a mean PNIF increase of 27 L/minute and a 3.5-point VAS improvement, while the INV insufficiency group (<i>n</i> = 60) showed greater gains (PNIF +35 L/minute; VAS +5 points).</p><p><strong>Conclusion: </strong>The modified spreader flap is an effective, cartilage-preserving technique for INV reconstruction, yielding consistent functional and aesthetic outcomes. Further controlled studies are required to assess long-term results.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148175718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aesthetic Outcomes, Complications, and Reported Long-Term Effects of Buccal Fat Pad Reduction: A Systematic Review.","authors":"Justin Shapiro, Alina Zgardau, Gabrielle Pundkay, Jamila Skinner, Zachary Sone, Zachary Solomon, Anthony Nichols, Shay I Duvdevani","doi":"10.1055/a-2875-0465","DOIUrl":"https://doi.org/10.1055/a-2875-0465","url":null,"abstract":"<p><strong>Introduction: </strong>Buccal fat pad reduction (BFPR) is increasingly used for lower facial contouring; however, long-term outcomes remain unclear.</p><p><strong>Objective and hypothesis: </strong>To evaluate aesthetic outcomes, patient satisfaction, complications, and long-term sequelae following BFPR. We hypothesized that the BFPR yields high satisfaction and favorable short-term outcomes with low complication rates, while long-term effects are underreported.</p><p><strong>Study design: </strong>Systematic review.</p><p><strong>Methods: </strong>A Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020-compliant review was conducted across MEDLINE, Embase, Web of Science, Scopus, and Cochrane CENTRAL through December 2025. Eligible studies reported aesthetic outcomes, satisfaction, or complications. PROSPERO registration: CRD420251274504.</p><p><strong>Results: </strong>Ten studies (<i>n</i> = 1,123) were analyzed. Objective assessments demonstrated a reduction in lower facial volume. Satisfaction was high. Among 921 procedures, 39 complications occurred (4.2%), mostly minor. Long-term outcomes were poorly assessed because follow-up was limited; one study reported a gaunt appearance (1.6%).</p><p><strong>Conclusion: </strong>BFPR appears safe with high satisfaction; however, evidence is limited by low-level studies and short follow-up.</p>","PeriodicalId":12195,"journal":{"name":"Facial Plastic Surgery","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148155878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}