Evidence-Based Medicine最新文献_第8页

Evidence-Based Medicine these 7 years: time for the editor to go on permanent sabbatical. 《循证医学》这7年:是编辑永久休假的时候了。

Evidence-Based Medicine Pub Date : 2017-06-01 Epub Date: 2017-04-20 DOI: 10.1136/ebmed-2017-110705

Richard Saitz

{"title":"<i>Evidence-Based Medicine</i> these 7 years: time for the editor to go on permanent sabbatical.","authors":"Richard Saitz","doi":"10.1136/ebmed-2017-110705","DOIUrl":"https://doi.org/10.1136/ebmed-2017-110705","url":null,"abstract":"Seven years seems the right term for an editorship. It is a time for the land that has been sown and reaped to remain uncultivated for a while (see Exodus or Leviticus , The Bible )—time for a sabbatical. When I came on in 2010, Evidence-Based Medicine (EBM) was already well established (for 15 years, its adolescence)1 as was the field of EBM (>3 years earlier, its birth).2 At the beginning, the journal aimed to serve this ‘emerging clinical discipline by providing easier access to high-quality evidence that is ready for prime-time clinical application’. The journal scanned a list of 29 other journals regularly, re-reported articles published in another journal as half of its content and added coverage beyond internal medicine. In the subsequent decade, it had published ‘notebook jottings’ on EBM, some of which reported on codified practices in the field.3 But it was time for the journal to branch out and for EBM the field to move from its establishment and definition to its real-life translation at the bedside.4 With a new editorial board, we aimed to support that transformation. We also aimed to be a home for EBMers, those who teach, study and practice EBM. To that end, we added a number of article types of relevance, beyond critically appraised articles and occasional musings.\u0000\u0000During the past 7 years, we published ∼1000 summaries and critical appraisals of original research studies selected systematically for clinical relevance and methodological strength. All were relatively brief but meaty enough at around 750 words to provide a bit of background and context, methods, main results (magnitude and precision), assessment of internal validity and applicability, and implications for research and practice, written by invited experts and edited by EBM-savvy clinician specialists in family medicine, internal medicine, obstetrics and gynaecology, and paediatrics.\u0000\u0000EBMers, EBM …","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":"22 3","pages":"79-80"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/ebmed-2017-110705","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34929059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Rating the certainty in evidence in the absence of a single estimate of effect. 在没有对效果进行单一估计的情况下对证据的确定性进行评级。

Evidence-Based Medicine Pub Date : 2017-06-01 Epub Date: 2017-03-20 DOI: 10.1136/ebmed-2017-110668

M Hassan Murad, Reem A Mustafa, Holger J Schünemann, Shahnaz Sultan, Nancy Santesso

引用次数: 320

Conduct and reporting of a vertebroplasty trial warrants critical examination. 椎体成形术试验的实施和报告需要严格的审查。

Evidence-Based Medicine Pub Date : 2017-06-01 Epub Date: 2017-03-29 DOI: 10.1136/ebmed-2016-110651

Rachelle Buchbinder, David F Kallmes, Jeffrey G Jarvik, Richard A Deyo

{"title":"Conduct and reporting of a vertebroplasty trial warrants critical examination.","authors":"Rachelle Buchbinder, David F Kallmes, Jeffrey G Jarvik, Richard A Deyo","doi":"10.1136/ebmed-2016-110651","DOIUrl":"https://doi.org/10.1136/ebmed-2016-110651","url":null,"abstract":"Commentary on: Clark W, Bird P, Gonski P, et al . Safety and efficacy of vertebroplasty for acute painful osteoporotic fractures (VAPOUR): a multicentre, randomised, double-blind, placebo-controlled trial. Lancet 2016;388:1408–16.\u0000\u0000Percutaneous vertebroplasty was widely used in patients with symptomatic acute vertebral compression fractures until two placebo randomised controlled trials (RCTs) published in 2009 questioned its efficacy and safety.1 ,2 Consistent results across both trials indicated vertebroplasty was no more effective than placebo, while a combined individual patient metaanalysis failed to show an advantage for vertebroplasty for participants with fracture ≤6 weeks.3 Despite these data, some have suggested that there may be subgroups that would benefit from vertebroplasty.\u0000\u0000VAPOUR was a multicentre participant-blinded and outcome assessor-blinded RCT assessing the efficacy of vertebroplasty versus placebo in 120 participants with acute (<6 weeks), severely painful vertebral compression fractures.4 The primary outcome was the proportion of …","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":"22 3","pages":"106-107"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/ebmed-2016-110651","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34867793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Abdominal electroacupuncture demonstrates an increase in complete spontaneous bowel movements. 腹部电针显示完全自发排便增加。

Evidence-Based Medicine Pub Date : 2017-06-01 Epub Date: 2017-05-12 DOI: 10.1136/ebmed-2017-110719

Deepti Jacob, Priya Vijayvargiya, Michael Camilleri

引用次数: 0

Possible protective effect of prenatal omega-3 long-chain polyunsaturated fatty acids supplementation on persistent wheeze and asthma in early childhood. 产前补充omega-3长链多不饱和脂肪酸对儿童早期持续性喘息和哮喘的可能保护作用。

Evidence-Based Medicine Pub Date : 2017-06-01 Epub Date: 2017-05-12 DOI: 10.1136/ebmed-2017-110696

Karen Best, Maria Makrides

引用次数: 6

Intensive blood pressure lowering provides no additional benefits and results in more adverse events. 强化降压不会带来额外的好处，反而会导致更多的不良事件。

Evidence-Based Medicine Pub Date : 2017-06-01 Epub Date: 2017-05-25 DOI: 10.1136/ebmed-2016-110594

Else Charlotte Sandset, Urs Fischer

引用次数: 1

High-intensity exercise offers no additional benefit to moderate-intensity exercise in reducing liver fat in patients with non-alcoholic fatty liver disease. 在减少非酒精性脂肪肝患者的肝脏脂肪方面，高强度运动与中等强度运动相比没有额外的益处。

Evidence-Based Medicine Pub Date : 2017-06-01 Epub Date: 2017-06-03 DOI: 10.1136/ebmed-2016-110579

Daniel J Cuthbertson, Victoria S Sprung

引用次数: 0

Among opioid-naive patients receiving opioids, more intensive opioid prescribing in the first month is associated with transition to long-term opioid use. 在接受阿片类药物治疗的首次使用阿片类药物的患者中，第一个月更密集的阿片类药物处方与过渡到长期使用阿片类药物有关。

Evidence-Based Medicine Pub Date : 2017-06-01 Epub Date: 2017-05-13 DOI: 10.1136/ebmed-2017-110710

Marc R Larochelle

引用次数: 3

In children 7 years of age, prenatal antidepressant exposure is not associated with increased risk of poor behavioural outcomes after adjusting for maternal factors including antenatal mood. 在7岁的儿童中，在调整了包括产前情绪在内的母亲因素后，产前抗抑郁药物暴露与不良行为结果风险增加无关。

Evidence-Based Medicine Pub Date : 2017-06-01 Epub Date: 2017-03-27 DOI: 10.1136/ebmed-2016-110650

Salvatore Gentile, Maria Luigia Fusco

{"title":"In children 7 years of age, prenatal antidepressant exposure is not associated with increased risk of poor behavioural outcomes after adjusting for maternal factors including antenatal mood.","authors":"Salvatore Gentile, Maria Luigia Fusco","doi":"10.1136/ebmed-2016-110650","DOIUrl":"https://doi.org/10.1136/ebmed-2016-110650","url":null,"abstract":"Commentary on: Grzeskowiak LE, Morrison JL, Henriksen TB, et al . Prenatal antidepressant exposure and child behavioural outcomes at 7 years of age: a study within the Danish National Birth Cohort. BJOG 2016;123:1919–28.\u0000\u0000The effect of prenatal antidepressant exposure or untreated maternal depression on child behaviour is an emerging field of research in perinatal psychiatry. This study attempts to clarify the impact of prenatal antidepressant exposure on long-term child outcomes, accounting for antenatal maternal factors, including depression.\u0000\u0000This study was conducted using data from 49 178 mother–child dyads enrolled in the Danish National Birth Cohort—a nationwide longitudinal follow-up study of pregnant women and their children. The overall cohort includes more than 100 000 women who were pregnant between 1996 and 2002. Maternal depression and medication use was assessed via self-report using computer-assisted telephone interviews conducted during pregnancy. Children were categorised as: born to depressed women who took antidepressants during pregnancy (n=210); born to untreated depressed women (n=231) and …","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":"22 3","pages":"113-114"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/ebmed-2016-110650","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34860031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Resumption of anticoagulation after major bleeding decreases the risk of stroke in patients with atrial fibrillation. 大出血后恢复抗凝可降低房颤患者卒中的风险。

Evidence-Based Medicine Pub Date : 2017-06-01 Epub Date: 2017-05-16 DOI: 10.1136/ebmed-2017-110694

Marcelle D Smit, Isabelle C Van Gelder

{"title":"Resumption of anticoagulation after major bleeding decreases the risk of stroke in patients with atrial fibrillation.","authors":"Marcelle D Smit, Isabelle C Van Gelder","doi":"10.1136/ebmed-2017-110694","DOIUrl":"https://doi.org/10.1136/ebmed-2017-110694","url":null,"abstract":"Commentary on: Hernandez I, Zhang Y, Brooks MM, et al . Anticoagulation use and clinical outcomes after major bleeding on dabigatran or warfarin in atrial fibrillation. Stroke 2017;48:159–66.\u0000\u0000Anticoagulation decreases the risk of stroke and other thromboembolic complications in patients with atrial fibrillation (AF) at the cost of an increased risk of major bleeding. If patients experience an anticoagulation-related major bleeding complication, the clinician faces the dilemma of whether to resume anticoagulation treatment or not. Evidence-based recommendations are lacking,1 and there is a wide variation in treatment of these patients, with anticoagulants, antiplatelets or no anticoagulation at all, while there is even less experience with non-vitamin K oral anticoagulants (NOACs), such as dabigatran. This study aimed to (1) evaluate anticoagulation use after a major bleeding event on dabigatran or warfarin and (2) compare outcomes between patients discontinuing anticoagulation and those restarting dabigatran or warfarin.\u0000\u0000This was …","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":"22 3","pages":"107-108"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/ebmed-2017-110694","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35001939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5