在接受阿片类药物治疗的首次使用阿片类药物的患者中,第一个月更密集的阿片类药物处方与过渡到长期使用阿片类药物有关。

Evidence-Based Medicine Pub Date : 2017-06-01 Epub Date: 2017-05-13 DOI:10.1136/ebmed-2017-110710
Marc R Larochelle
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引用次数: 3

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本文章由计算机程序翻译,如有差异,请以英文原文为准。
Among opioid-naive patients receiving opioids, more intensive opioid prescribing in the first month is associated with transition to long-term opioid use.
Commentary on:  Deyo RA, Hallvik SE, Hildebran C, et al . Association between initial opioid prescribing patterns and subsequent long-term use among opioid-naive patients: a statewide retrospective cohort study. J Gen Intern Med 2017;32(1):21-7. A recent systematic review of long-term opioid use for chronic pain found that evidence is lacking to support benefit from long-term opioid therapy, and evidence supports a dose-dependent risk of opioid-related harms including overdose and death.1 Despite the evidence, an estimated 5 to 8 million Americans receive long-term opioid therapy.2 Understanding the transition from acute or episodic use of opioids to long-term opioid use may help design interventions to reduce the incidence of long-term opioid use. This study sought to analyse the association between prescribing patterns in the first 30 days of opioid receipt among formerly opioid-naive subjects and transitioning to long-term opioid use. …
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