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Prescribing antibiotics to hospitalised patients increases the risk of Clostridium difficile infection for the next bed occupant. 给住院病人开抗生素会增加下一个病人感染艰难梭菌的风险。
Evidence-Based Medicine Pub Date : 2017-12-01 Epub Date: 2017-10-25 DOI: 10.1136/ebmed-2017-110725
Nick Daneman
{"title":"Prescribing antibiotics to hospitalised patients increases the risk of <i>Clostridium difficile</i> infection for the next bed occupant.","authors":"Nick Daneman","doi":"10.1136/ebmed-2017-110725","DOIUrl":"https://doi.org/10.1136/ebmed-2017-110725","url":null,"abstract":"Commentary on: Freedberg DE, Salmasian H, Cohen B, et al . Receipt of antibiotics in hospitalized patients and risk for Clostridium difficile infection in subsequent patients who occupy the same bed . JAMA Intern Med 2016;176:1801–8.\u0000\u0000Patients are at heightened risk of Clostridium difficile- associated disease when they are exposed to both the organism and to antibiotic treatments, which deplete their normal, diverse, protective gastrointestinal flora. Both of these factors are prevalent in healthcare facilities, and thus C. difficile is the most common and most burdensome hospital-acquired pathogen.1 The hazards of antibiotic use may extend beyond the individual patient. As ward-level antibiotic use increases, so too does an individual patient’s risk of C. difficile infection, even when he or she has not directly received antibiotics.2 In this study, Freedberg et al aim to provide perhaps the most direct evidence of the indirect hazards of antibiotic use on the risk of C. difficile —by testing whether antibiotic receipt by a …","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":" ","pages":"212"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/ebmed-2017-110725","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35543619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stent choice in cardiogenic shock complicating acute myocardial infarction likely does not affect mortality or reinfarction. 心源性休克并发急性心肌梗死的支架选择可能不会影响死亡率或再梗死。
Evidence-Based Medicine Pub Date : 2017-12-01 Epub Date: 2017-11-04 DOI: 10.1136/ebmed-2017-110841
Talla A Rousan, Udho Thadani
{"title":"Stent choice in cardiogenic shock complicating acute myocardial infarction likely does not affect mortality or reinfarction.","authors":"Talla A Rousan, Udho Thadani","doi":"10.1136/ebmed-2017-110841","DOIUrl":"10.1136/ebmed-2017-110841","url":null,"abstract":"","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":" ","pages":"224"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35522287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acupuncture is not as effective as infertility treatment in women with PCOS. 针灸治疗多囊卵巢综合征的效果不如不孕不育。
Evidence-Based Medicine Pub Date : 2017-12-01 Epub Date: 2017-10-22 DOI: 10.1136/ebmed-2017-110828
Liangzhi Xu, Xiaoyong Qiao
{"title":"Acupuncture is not as effective as infertility treatment in women with PCOS.","authors":"Liangzhi Xu, Xiaoyong Qiao","doi":"10.1136/ebmed-2017-110828","DOIUrl":"10.1136/ebmed-2017-110828","url":null,"abstract":"","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":" ","pages":"229-230"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7a/be/ebmed-2017-110828.PMC5750408.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35535242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early invasive strategy should be performed within 72 hours in high-risk patients with non-ST-elevation myocardial infarction. 非st段抬高型心肌梗死高危患者应在72小时内行早期有创策略。
Evidence-Based Medicine Pub Date : 2017-12-01 Epub Date: 2017-11-23 DOI: 10.1136/ebmed-2017-110848
Carlos Collet, Patrick W Serruys
{"title":"Early invasive strategy should be performed within 72 hours in high-risk patients with non-ST-elevation myocardial infarction.","authors":"Carlos Collet, Patrick W Serruys","doi":"10.1136/ebmed-2017-110848","DOIUrl":"10.1136/ebmed-2017-110848","url":null,"abstract":"","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":" ","pages":"227"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35634300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prophylactic platelet transfusion does not reduce risk of clinical bleeding in adults with dengue and thrombocytopaenia. 预防性血小板输注不能降低成人登革热和血小板减少症患者的临床出血风险。
Evidence-Based Medicine Pub Date : 2017-12-01 Epub Date: 2017-11-02 DOI: 10.1136/ebmed-2017-110745
Muhammad Zaman Khan Assir, Fraz Ahmad
{"title":"Prophylactic platelet transfusion does not reduce risk of clinical bleeding in adults with dengue and thrombocytopaenia.","authors":"Muhammad Zaman Khan Assir, Fraz Ahmad","doi":"10.1136/ebmed-2017-110745","DOIUrl":"10.1136/ebmed-2017-110745","url":null,"abstract":"","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":" ","pages":"225"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35219005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cephalexin plus trimethoprim-sulfamethoxazole was not superior to cephalexin alone for the treatment of outpatient non-purulent cellulitis. 头孢氨苄联合甲氧苄氨苄磺胺甲恶唑治疗门诊非化脓性蜂窝织炎并不优于头孢氨苄单用。
Evidence-Based Medicine Pub Date : 2017-12-01 Epub Date: 2017-11-10 DOI: 10.1136/ebmed-2017-110796
Loren G Miller
{"title":"Cephalexin plus trimethoprim-sulfamethoxazole was not superior to cephalexin alone for the treatment of outpatient non-purulent cellulitis.","authors":"Loren G Miller","doi":"10.1136/ebmed-2017-110796","DOIUrl":"10.1136/ebmed-2017-110796","url":null,"abstract":"","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":" ","pages":"213"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35543507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute myocardial infarction can be ruled out with a single high-sensitivity cardiac troponin T level. 急性心肌梗死可以排除单一的高灵敏度心肌肌钙蛋白T水平。
Evidence-Based Medicine Pub Date : 2017-12-01 Epub Date: 2017-09-18 DOI: 10.1136/ebmed-2017-110812
Martin J Holzmann
{"title":"Acute myocardial infarction can be ruled out with a single high-sensitivity cardiac troponin T level.","authors":"Martin J Holzmann","doi":"10.1136/ebmed-2017-110812","DOIUrl":"https://doi.org/10.1136/ebmed-2017-110812","url":null,"abstract":"Commentary on: Pickering JW, Than P, Cullen L, et al . Rapid rule-out of acute myocardial infarction with a single high-sensitivity cardiac troponin T measurement below the limit of detection. Ann Intern Med  2017;166:715–24.\u0000\u0000Historically, it has been regarded that at least two measurements of cardiac biomarkers, with 6 hours in between, are needed in order to rule out acute myocardial infarction (AMI). With the introduction of high-sensitivity cardiac troponin (hs-cTn) assays, the time it takes to detect signs of myocyte necrosis has shortened considerably.1 In an observational cohort study published in 2014, it was found that the risk of AMI within 30 days was 0.2% if the first high-sensitivity cardiac troponin T (hs-cTnT) measurement was <5 ng/L.2 The authors suggested that it was safe to discharge all patients with chest pain with a non-ischaemic ECG, if the first …","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":" ","pages":"226"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/ebmed-2017-110812","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35421719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A meta-analysis of positive airway pressure treatment for cardiovascular prevention: why mix apples and pears? 正压通气治疗预防心血管疾病的荟萃分析：为什么要把苹果和梨混在一起？
Evidence-Based Medicine Pub Date : 2017-12-01 Epub Date: 2017-11-18 DOI: 10.1136/ebmed-2017-110835
Yüksel Peker, Patrick J Strollo
{"title":"A meta-analysis of positive airway pressure treatment for cardiovascular prevention: why mix apples and pears?","authors":"Yüksel Peker, Patrick J Strollo","doi":"10.1136/ebmed-2017-110835","DOIUrl":"10.1136/ebmed-2017-110835","url":null,"abstract":"","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":" ","pages":"218-219"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/49/13/ebmed-2017-110835.PMC5750407.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35259175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Haem iron and nitrate/nitrite account for much of the mortality increase associated with red meat consumption. 血红素铁和硝酸盐/亚硝酸盐是与食用红肉相关的死亡率增加的主要原因。
Evidence-Based Medicine Pub Date : 2017-10-01 Epub Date: 2017-08-16 DOI: 10.1136/ebmed-2017-110787
Sabine Rohrmann, Jakob Linseisen
{"title":"Haem iron and nitrate/nitrite account for much of the mortality increase associated with red meat consumption.","authors":"Sabine Rohrmann,&nbsp;Jakob Linseisen","doi":"10.1136/ebmed-2017-110787","DOIUrl":"https://doi.org/10.1136/ebmed-2017-110787","url":null,"abstract":"Commentary on: Etemadi, A, Sinha R, Ward MH, et al. Mortality from different causes associated with meat, heme iron, nitrates, and nitrites in the NIH-AARP Diet and Health Study: population based cohort study.  BMJ 2017;357:j1957.\u0000\u0000The International Agency for Research on Cancer categorised processed meat as carcinogenic to humans in 2015.1 High red and processed meat consumption is positively associated with risk of cardiovascular disease and type 2 diabetes as well as overall mortality.2 Usually the intake of processed red meat is found to be more strongly associated with disease outcomes than unprocessed red meat, which is thought to be due to preservation methods such as salting, curing and smoking, increasing the concentration of potentially hazardous substances in meat.3 \u0000\u0000In the US National Institutes of Health-American Association of Retired Persons (NIH-AARP) …","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":"22 5","pages":"179"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/ebmed-2017-110787","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35328649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of interventions based on implantable devices: meta-analyses or systematic reviews that fail to indicate which device brands were used. 基于植入式设备的干预措施的有效性:未能表明使用了哪些设备品牌的荟萃分析或系统评价。
Evidence-Based Medicine Pub Date : 2017-10-01 Epub Date: 2017-08-29 DOI: 10.1136/ebmed-2017-110802
Andrea Messori, Sabrina Trippoli, Claudio Marinai
{"title":"Effectiveness of interventions based on implantable devices: meta-analyses or systematic reviews that fail to indicate which device brands were used.","authors":"Andrea Messori,&nbsp;Sabrina Trippoli,&nbsp;Claudio Marinai","doi":"10.1136/ebmed-2017-110802","DOIUrl":"https://doi.org/10.1136/ebmed-2017-110802","url":null,"abstract":"We recently surveyed the literature on the effectiveness of three classes of implantable devices: (1) stents for carotid artery stenosis, (2) endovascular clips or coils for unruptured intracranial aneurysms and (3) prostheses for endovascular treatment of ruptured abdominal aneurysms. These three device-based interventions were selected because, at our Regional Health System, we were requested to undertake a series of competitive tenders for the procurement of these devices.\u0000\u0000To synthetise the clinical literature on these topics, we adopted the empirical criterion of identifying—by expert consensus—the ‘best’ single meta-analysis …","PeriodicalId":12182,"journal":{"name":"Evidence-Based Medicine","volume":"22 5","pages":"195"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/ebmed-2017-110802","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35455834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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