European Psychiatry最新文献

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Prevalence and comorbidity rates of disruptive mood dysregulation disorder in epidemiological and clinical samples: systematic review and meta-analysis. 流行病学和临床样本中破坏性情绪失调障碍的患病率和合并率:系统回顾和荟萃分析。
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-01-15 DOI: 10.1192/j.eurpsy.2024.1813
Xavier Benarous, Hélène Lahaye, Angèle Consoli, David Cohen, Réal Labelle, Jean-Marc Guilé
{"title":"Prevalence and comorbidity rates of disruptive mood dysregulation disorder in epidemiological and clinical samples: systematic review and meta-analysis.","authors":"Xavier Benarous, Hélène Lahaye, Angèle Consoli, David Cohen, Réal Labelle, Jean-Marc Guilé","doi":"10.1192/j.eurpsy.2024.1813","DOIUrl":"10.1192/j.eurpsy.2024.1813","url":null,"abstract":"<p><strong>Background: </strong>This systematic review and meta-analysis evaluates the prevalence of disruptive mood dysregulation disorders (DMDD) in community-based and clinical populations.</p><p><strong>Methods: </strong>PubMed and PsychINFO databases were searched, using terms specific to DMDD, for studies of prevalence and comorbidity rates conducted in youths below 18.</p><p><strong>Results: </strong>Fourteen studies reporting data from 2013 to 2023 were included. The prevalence of DMDD in the community-based samples was 3.3% (95% confidence interval [CI], 1.4-6.0) and 21.9% (95% CI, 15.5-29.0) in the clinical population. The differences in the identification strategy of DMDD were associated with significant heterogeneity between studies in the community-based samples, with a prevalence of 0.82% (95% CI, 0.11-2.13) when all diagnosis criteria were considered. Anxiety, depressive disorders, and ADHD were the most frequent comorbidity present with DMDD. The association with other neurodevelopmental disorders remained poorly investigated.</p><p><strong>Conclusions: </strong>Caution is required when interpreting these findings, considering the quality of the reviewed data and the level of unexplained heterogeneity among studies. This review stresses the importance of considering a strict adhesion to DMDD criteria when exploring its clinical correlates.</p>","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"e11"},"PeriodicalIF":7.2,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11795450/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142983182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
International perspective on social cognition in schizophrenia: current stage and the next steps. 精神分裂症社会认知的国际视角:当前阶段和下一步。
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-01-15 DOI: 10.1192/j.eurpsy.2024.1776
Silvia Corbera, Matthew M Kurtz, Amélie M Achim, Giulia Agostoni, Isabelle Amado, Michal Assaf, Stefano Barlati, Margherita Bechi, Roberto Cavallaro, Satoru Ikezawa, Hiroki Okano, Ryo Okubo, Rafael Penadés, Takashi Uchino, Antonio Vita, Yuji Yamada, Morris D Bell
{"title":"International perspective on social cognition in schizophrenia: current stage and the next steps.","authors":"Silvia Corbera, Matthew M Kurtz, Amélie M Achim, Giulia Agostoni, Isabelle Amado, Michal Assaf, Stefano Barlati, Margherita Bechi, Roberto Cavallaro, Satoru Ikezawa, Hiroki Okano, Ryo Okubo, Rafael Penadés, Takashi Uchino, Antonio Vita, Yuji Yamada, Morris D Bell","doi":"10.1192/j.eurpsy.2024.1776","DOIUrl":"10.1192/j.eurpsy.2024.1776","url":null,"abstract":"<p><p>In the last decades, research from cognitive science, clinical psychology, psychiatry, and social neuroscience has provided mounting evidence that several social cognitive abilities are impaired in people with schizophrenia and contribute to functional difficulties and poor clinical outcomes. Social dysfunction is a hallmark of the illness, and yet, social cognition is seldom assessed in clinical practice or targeted for treatment. In this article, 17 international experts, from three different continents and six countries with expertise in social cognition and social neuroscience in schizophrenia, convened several meetings to provide clinicians with a summary of the most recent international research on social cognition evaluation and treatment in schizophrenia, and to lay out primary recommendations and procedures that can be integrated into their practice. Given that many extant measures used to assess social cognition have been developed in North America or Western Europe, this article is also a call for researchers and clinicians to validate instruments internationally and we provide preliminary guidance for the adaptation and use of social cognitive measures in clinical and research evaluations internationally. This effort will assist promoting scientific rigor, enhanced clinical practice, and will help propel international scientific research and collaboration and patient care.</p>","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"e9"},"PeriodicalIF":7.2,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11795453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142983179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hospitalizations with post-traumatic stress disorder in France between 2013 and 2022: a nationwide retrospective study. 2013年至2022年法国创伤后应激障碍住院:一项全国性的回顾性研究。
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-01-15 DOI: 10.1192/j.eurpsy.2024.1810
Alice Demesmaeker, Florian Dufrenois, Chloé Saint-Dizier, Guillaume Vaiva, Antoine Lamer, Mathilde Horn, Fabien D'Hondt
{"title":"Hospitalizations with post-traumatic stress disorder in France between 2013 and 2022: a nationwide retrospective study.","authors":"Alice Demesmaeker, Florian Dufrenois, Chloé Saint-Dizier, Guillaume Vaiva, Antoine Lamer, Mathilde Horn, Fabien D'Hondt","doi":"10.1192/j.eurpsy.2024.1810","DOIUrl":"10.1192/j.eurpsy.2024.1810","url":null,"abstract":"<p><strong>Introduction: </strong>The lifetime prevalence of PTSD ranges from 6 to 20% and is often associated with comorbid disorders. Despite the significant impact of PTSD, specific data on healthcare utilization related to PTSD remain limited. This study aims to characterize PTSD-related hospitalizations in France over the past decade.</p><p><strong>Methods: </strong>This nationwide longitudinal retrospective study analyzed PTSD-related hospitalizations in France from 2013 to 2022 using the French National Hospitals Database. Data included discharge records from general and psychiatric hospitals, detailing demographics, admission/discharge dates, ICD-10 diagnoses, and hospitalization specifics.</p><p><strong>Results: </strong>Between 2013 and 2022, 69,108 patients underwent 125,349 hospitalizations with a PTSD diagnosis (0.4% of all inpatient cases) in France. Psychiatric facilities accounted for 74,988 hospitalizations (1% of all psychiatric inpatient cases in France), while general hospitals recorded 50,361 hospitalizations (0.02% of all non-psychiatric inpatient cases). The percentage of inpatients diagnosed with PTSD increased from 0.68 to 2.22% in psychiatric facilities and from 0.02 to 0.04% in general hospitals over the study period. Females were younger in both settings and had longer stays compared to males in psychiatric facilities. Over time, there was a decrease in median age and an increase in part-time hospitalizations in psychiatric facilities. Mood disorders, stress-related disorders, and substance use disorders were prevalent comorbidities in both settings.</p><p><strong>Conclusions: </strong>This study highlights a rise in PTSD-related hospitalizations in France, particularly in psychiatric facilities and after 2019, with high rates among women and an increase in hospitalization of younger individuals. These findings highlight the necessity for improved care strategies tailored to the increasing number of younger patients with PTSD.</p>","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"e10"},"PeriodicalIF":7.2,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11795449/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142983165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early career psychiatrists' perceptions of and training experience in electroconvulsive therapy: A cross-sectional survey across Europe. 早期职业精神科医生对电休克疗法的认知和培训经验:一项横跨欧洲的横断面调查。
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-01-13 DOI: 10.1192/j.eurpsy.2024.1798
Cristiana Țăpoi, Laith Alexander, Renato de Filippis, Agorastos Agorastos, Diogo Almeida, Gautam Bhatia, Gamze Erzin, Martyna Ewa Gołębiewska, Enita Metaj, Sara Medved, Krista Mieze, Miloš Milutinović, Camille Noël, Antonina Pushko, David Gurrea Salas, Alejandro Compaired Sanchez, Alina Wilkowska, Rick P F Wolthusen, Mariana Pinto da Costa
{"title":"Early career psychiatrists' perceptions of and training experience in electroconvulsive therapy: A cross-sectional survey across Europe.","authors":"Cristiana Țăpoi, Laith Alexander, Renato de Filippis, Agorastos Agorastos, Diogo Almeida, Gautam Bhatia, Gamze Erzin, Martyna Ewa Gołębiewska, Enita Metaj, Sara Medved, Krista Mieze, Miloš Milutinović, Camille Noël, Antonina Pushko, David Gurrea Salas, Alejandro Compaired Sanchez, Alina Wilkowska, Rick P F Wolthusen, Mariana Pinto da Costa","doi":"10.1192/j.eurpsy.2024.1798","DOIUrl":"10.1192/j.eurpsy.2024.1798","url":null,"abstract":"<p><strong>Background: </strong>Electroconvulsive therapy (ECT) is a safe and effective treatment for several major psychiatric conditions, including treatment-resistant depression, mania, and schizophrenia; nevertheless, its use remains controversial. Despite its availability in some European countries, ECT is still rarely used in others. This study aims to investigate the experiences and attitudes of early career psychiatrists (ECPs) across Europe towards ECT and to examine how their exposure to ECT influences their perceptions.</p><p><strong>Methods: </strong>In Europe, a cross-sectional survey was conducted among ECPs, including psychiatric trainees and recently fully qualified psychiatrists.</p><p><strong>Results: </strong>A total of 573 participants from 30 European countries were included in the study, of whom more than half (<i>N</i> = 312; 54.5%) received ECT training. Overall, ECPs had a positive attitude towards ECT, with the vast majority agreeing or strongly agreeing that ECT is an effective (<i>N</i> = 509; 88.8%) and safe (<i>N</i> = 464; 81.0%) treatment and disagreeing or strongly disagreeing that ECT was used as a form of control or punishment (<i>N</i> = 545; 95.1%). Those who had received ECT training during their psychiatry training were more likely to recommend ECT to their patients (p < 0.001, r = 0.34), and held more positive views on its safety (p < 0.001, r = 0.31) and effectiveness (p < 0.001, r = 0.33). Interest in further education about ECT was moderately high (modal rating on Likert scale: 4, agree), irrespective of prior training exposure.</p><p><strong>Conclusions: </strong>ECT training is associated with more favorable perceptions of its safety and effectiveness among ECPs. There is a general willingness among ECPs to expand their knowledge and training on ECT, which could enhance patients' access to this treatment.</p>","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":"67 1","pages":"e86"},"PeriodicalIF":7.2,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733618/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An intersectional examination of the relationship between racial/ethnic discrimination and psychotic-like experiences: the role of other psychiatric symptoms. 种族/民族歧视与类精神病经历之间关系的交叉检验:其他精神症状的作用。
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-01-13 DOI: 10.1192/j.eurpsy.2024.1796
Arielle Ered, Emily Lipner, Kathleen J O'Brien, Zeeshan M Huque, Deidre M Anglin, Lauren M Ellman
{"title":"An intersectional examination of the relationship between racial/ethnic discrimination and psychotic-like experiences: the role of other psychiatric symptoms.","authors":"Arielle Ered, Emily Lipner, Kathleen J O'Brien, Zeeshan M Huque, Deidre M Anglin, Lauren M Ellman","doi":"10.1192/j.eurpsy.2024.1796","DOIUrl":"10.1192/j.eurpsy.2024.1796","url":null,"abstract":"<p><strong>Background: </strong>Racial and ethnic experiences of discrimination (EODs) are associated with numerous psychiatric symptoms, including outcomes along the psychosis spectrum; however, less is known about mechanisms by which EODs confer risk for psychotic-like experiences (PLEs; common subthreshold psychotic symptoms). Furthermore, work on gendered racism asserts that the intersection of race and gender impacts the nature of EODs experienced and, in turn, may impact the relationship between EODs and PLEs.</p><p><strong>Aims: </strong>To utilize an intersectional lens (race and gender) to examine whether psychological correlates of EODs (post-traumatic stress, anxiety, depression, and dissociation) mediate the EOD-PLE relationship.</p><p><strong>Methods: </strong>Undergraduates at a diverse, semipublic university (<i>N</i> = 1,759) completed self-report questionnaires (Experiences of Discrimination Scale, Prodromal Questionnaire, Center for Epidemiologic Studies Depression Scale, State-Trait Anxiety Inventory, Dissociative Experiences Scale, and Post-Traumatic Stress Disorder Checklist - Civilian Version). Analyses stratified the sample by race (non-Hispanic White, Black, and Asian) and examined three multiple mediation models, moderated by gender, examining the pathway from EODs to PLEs, through other psychiatric symptoms.</p><p><strong>Results: </strong>In the full sample, all psychiatric symptoms significantly mediated the relationship between EODs and PLEs. Only depression varied by gender, such that the indirect effect was only significant in female participants (<i>β</i> = 0.09; 95% CI [0.02, 0.16]). Across race-stratified groups, significant mediators varied by both race and gender.</p><p><strong>Conclusions: </strong>These findings underscore the importance of accounting for intersectionality and multiple psychological symptoms in understanding the EOD-PLE associations, which differ by race and ethnicity as well as gender, and should be considered in clinical treatment of individuals with PLEs and history of EODs.</p>","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":"68 1","pages":"e6"},"PeriodicalIF":7.2,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11795428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictive accuracy of the Violence Risk Assessment Checklist for Youth in acute institutions: A prospective naturalistic multicenter study. 急性机构青少年暴力风险评估清单的预测准确性-一项前瞻性自然主义多中心研究。
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-01-13 DOI: 10.1192/j.eurpsy.2025.3
Anniken Lucia Willumsen Laake, John Olav Roaldset, Tonje Lossius Husum, Stål Kapstø Bjørkly, Carina Chudiakow Gustavsen, Sara Teresia Grenabo, Øyvind Lockertsen
{"title":"Predictive accuracy of the Violence Risk Assessment Checklist for Youth in acute institutions: A prospective naturalistic multicenter study.","authors":"Anniken Lucia Willumsen Laake, John Olav Roaldset, Tonje Lossius Husum, Stål Kapstø Bjørkly, Carina Chudiakow Gustavsen, Sara Teresia Grenabo, Øyvind Lockertsen","doi":"10.1192/j.eurpsy.2025.3","DOIUrl":"10.1192/j.eurpsy.2025.3","url":null,"abstract":"<p><strong>Background: </strong>Acute health and social services for children and adolescents often struggle with youth aggression and violence. Early identification of violence risk during institutional stay can help prevent violent incidents. As such, this study assessed the predictive accuracy of the Violence Risk Assessment Checklist for Youth (V-RISK-Y) aged 12-18 in two different juvenile settings providing 24-hour services for youth. Institutions were included from child and adolescent inpatient psychiatry and residential youth care under child protective services.</p><p><strong>Methods: </strong>A prospective, naturalistic observational study design was employed. V-RISK-Y was administered for youth admitted to four acute inpatient psychiatric units and four acute residential youth care institutions. Incidents of violence and threats during the youth's stay were registered by institutional staff. In total, 517 youth were included in analyses, 59 of whom were registered with at least one incident of violence or threats during their stay. Area under curve (AUC) and logistic regression analyses were used to assess predictive accuracy and validity of V-RISK-Y.</p><p><strong>Results: </strong>For the overall sample, V-RISK-Y had good predictive accuracy, and the sum score of V-RISK-Y significantly predicted registered violent incidents. Stratified analyses indicated good predictive accuracy of V-RISK-Y for the inpatient units, but not for the residential youth care institutions.</p><p><strong>Conclusions: </strong>Findings imply that V-RISK-Y is accurate in identifying violence risk for youth admitted to inpatient psychiatric units but has limited predictive accuracy in residential youth care institutions. Future research should explore approaches to correctly identify violence risk in residential care settings.</p>","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"e19"},"PeriodicalIF":7.2,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11822959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of psychedelic treatments in psychiatric clinical practice: an EPA policy paper. 在精神病临床实践中使用致幻剂治疗:EPA政策文件。
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-01-10 DOI: 10.1192/j.eurpsy.2024.1806
M Destoop, P Mohr, F Butlen, P Kéri, J Samochowiec, L De Picker, A Fiorillo, K P C Kuypers, G Dom
{"title":"Use of psychedelic treatments in psychiatric clinical practice: an EPA policy paper.","authors":"M Destoop, P Mohr, F Butlen, P Kéri, J Samochowiec, L De Picker, A Fiorillo, K P C Kuypers, G Dom","doi":"10.1192/j.eurpsy.2024.1806","DOIUrl":"10.1192/j.eurpsy.2024.1806","url":null,"abstract":"<p><strong>Background: </strong>Recent years show an exponential increased interest (\"renaissance\") in the use of psychedelics for the treatment of mental disorders and broader. Some of these treatments, such as psilocybin for depression, are in the process of formal regulation by regulatory bodies in the US (FDA) and Europe (EMA), and as such on the brink of real-world implementation. In the slipstream of these developments increasing commercial initiatives are taking shape. The European Psychiatric Association (EPA) acknowledges both the therapeutic potential of psychedelic substances and the challenges for both research and clinical implementation. Steps need to be taken toward a well-balanced policy based upon sound scientific evidence and research, aiming at safe, ethical responsible integration of psychedelic therapy available for all patients who can potentially benefit.</p><p><strong>Methods: </strong>In this EPA policy paper, we highlight the potential benefits, and also the challenges of psychedelic treatments, which can be relevant for the future real-world implementation of these treatments.</p><p><strong>Results: </strong>In addition to an overview of the current evidence and hypotheses of working mechanisms of psychedelic treatment, this policy paper specifically highlights the importance of the psychosocial components of the treatment as well as the ethical and professional aspects playing a role in real-world implementation.</p><p><strong>Conclusions: </strong>Four recommendations are formulated for further research and clinical implementation.</p>","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":"68 1","pages":"e3"},"PeriodicalIF":7.2,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11795445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142946871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Positive associations between mean ambient temperature and involuntary admissions to psychiatric facilities. 平均环境温度与精神病院非自愿入院之间的正相关。
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-01-10 DOI: 10.1192/j.eurpsy.2024.1800
Noah L Joore, Marte Z van der Horst, Eric O Noorthoorn, Jurriaan F M Strous, Fleur J Vruwink, Sinan Guloksuz, Peter C Siegmund, Jurjen J Luykx
{"title":"Positive associations between mean ambient temperature and involuntary admissions to psychiatric facilities.","authors":"Noah L Joore, Marte Z van der Horst, Eric O Noorthoorn, Jurriaan F M Strous, Fleur J Vruwink, Sinan Guloksuz, Peter C Siegmund, Jurjen J Luykx","doi":"10.1192/j.eurpsy.2024.1800","DOIUrl":"10.1192/j.eurpsy.2024.1800","url":null,"abstract":"<p><strong>Background: </strong>Temperature increases in the context of climate change affect numerous mental health outcomes. One such relevant outcome is involuntary admissions as these often relate to severe (life)threatening psychiatric conditions. Due to a shortage of studies into this topic, relationships between mean ambient temperature and involuntary admissions have remained largely elusive.</p><p><strong>Aims: </strong>To examine associations between involuntary admissions to psychiatric institutions and various meteorological variables.</p><p><strong>Methods: </strong>Involuntary admissions data from 23 psychiatric institutions in the Netherlands were linked to meteorological data from their respective weather stations. Generalized additive models were used, integrating a restricted maximum likelihood method and thin plate regression splines to preserve generalizability and minimize the risk of overfitting. We thus conducted univariable, seasonally stratified, multivariable, and lagged analyses.</p><p><strong>Results: </strong>A total of 13,746 involuntary admissions were included over 21,549 days. In univariable and multivariable models, we found significant positive associations with involuntary admissions for ambient temperature and windspeed, with projected increases of up to 0.94% in involuntary admissions per degree Celsius temperature elevation. In the univariable analyses using all data, the strongest associations in terms of significance and explained variance were found for mean ambient temperature (<i>p</i> = 2.5 × 10<sup>-6</sup>, Variance Explained [<i>r</i><sup>2</sup>] = 0.096%) and maximum ambient temperature (<i>p</i> = 8.65 × 10<sup>-4</sup>, <i>r</i><sup>2</sup> = 0.072%). We did not find evidence that the lagged associations explain the associations for ambient temperature better than the direct associations.</p><p><strong>Conclusion: </strong>Mean ambient temperature is consistently but weakly associated with involuntary psychiatric admissions. Our findings set the stage for further epidemiological and mechanistic studies into this topic, as well as for modeling studies examining future involuntary psychiatric admissions.</p>","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":"68 1","pages":"e2"},"PeriodicalIF":7.2,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11795429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142946932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The time has come for revising the rules of clozapine blood monitoring in Europe. A joint expert statement from the European Clozapine Task Force. 是时候修改欧洲氯氮平血液监测规则了。欧洲氯氮平特别工作组的联合专家声明。
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-01-10 DOI: 10.1192/j.eurpsy.2024.1816
Hélène Verdoux, Robert A Bittner, Alkomiet Hasan, Mishal Qubad, Elias Wagner, Alexis Lepetit, Manuel Arrojo-Romero, Christian Bachmann, Marieke Beex-Oosterhuis, Jan Bogers, Andreja Celofiga, Dan Cohen, Domenico de Berardis, Marc de Hert, Carlos de Las Cuevas, Bjørn H Ebdrup, Konstantinos N Fountoulakis, Daniel Guinart, Dolores Keating, Miloslav Kopeček, John Lally, Judit Lazáry, Jurjen J Luykx, Olalla Maronas Amigo, Espen Molden, Jimmi Nielsen, Brian O'Donoghue, Pierre Oswald, Flavian S Radulescu, Christopher Rohde, Marina Sagud, Emilio J Sanz, Ivona Šimunović Filipčić, Iris E Sommer, Heidi Taipale, Jari Tiihonen, Heli Tuppurainen, Selene Veerman, Alina Wilkowska, Edoardo Spina, Peter Schulte
{"title":"The time has come for revising the rules of clozapine blood monitoring in Europe. A joint expert statement from the European Clozapine Task Force.","authors":"Hélène Verdoux, Robert A Bittner, Alkomiet Hasan, Mishal Qubad, Elias Wagner, Alexis Lepetit, Manuel Arrojo-Romero, Christian Bachmann, Marieke Beex-Oosterhuis, Jan Bogers, Andreja Celofiga, Dan Cohen, Domenico de Berardis, Marc de Hert, Carlos de Las Cuevas, Bjørn H Ebdrup, Konstantinos N Fountoulakis, Daniel Guinart, Dolores Keating, Miloslav Kopeček, John Lally, Judit Lazáry, Jurjen J Luykx, Olalla Maronas Amigo, Espen Molden, Jimmi Nielsen, Brian O'Donoghue, Pierre Oswald, Flavian S Radulescu, Christopher Rohde, Marina Sagud, Emilio J Sanz, Ivona Šimunović Filipčić, Iris E Sommer, Heidi Taipale, Jari Tiihonen, Heli Tuppurainen, Selene Veerman, Alina Wilkowska, Edoardo Spina, Peter Schulte","doi":"10.1192/j.eurpsy.2024.1816","DOIUrl":"10.1192/j.eurpsy.2024.1816","url":null,"abstract":"<p><p>The European Clozapine Task Force is a group of psychiatrists and pharmacologists practicing in 18 countries under European Medicines Agency (EMA) regulation, who are deeply concerned about the underuse of clozapine in European countries. Although clozapine is the most effective antipsychotic for people with treatment-resistant schizophrenia, a large proportion of them do not have access to this treatment. Concerns about clozapine-induced agranulocytosis and stringent blood monitoring rules are major barriers to clozapine prescribing and use. There is a growing body of evidence that the incidence of clozapine-induced agranulocytosis is very low after the first year of treatment. Maintaining lifelong monthly blood monitoring after this period contributes to unjustified discontinuation of clozapine. We leverage recent and replicated evidence on the long-term safety of clozapine to call for the revision and updating of the EMA's blood monitoring rules, thus aiming to overcome this major barrier to clozapine prescribing and use. We believe the time has come for relaxing the rules without increasing the risks for people using clozapine in Europe.</p>","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":" ","pages":"e17"},"PeriodicalIF":7.2,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11822956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142946927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Symptomatic networks in suicide attempt and reattempt: Relevance of psychiatric comorbidity. 自杀企图和再自杀的症状网络:精神合并症的相关性。
IF 7.2 2区 医学
European Psychiatry Pub Date : 2025-01-10 DOI: 10.1192/j.eurpsy.2024.1807
Andres Pemau, Alejandro de la Torre-Luque, Carolina Marin-Martin, Marina Diaz-Marsa, Jorge Andreo-Jover, Wala Ayad-Ahmed, Maria Fe Bravo Ortiz, Maria Teresa Bobes-Bascarán, Manuel Canal-Rivero, Irene Canosa García, Ana Isabel Cebrià, Benedicto Crespo-Facorro, María Ángeles Boti, Matilde Elices, Ana González-Pinto, Iria Grande, Luis Jiménez-Treviño, Diego J Palao, Angela Palao-Tarrero, Carla Pérez-Guerra, Natalia Roberto, Miguel Ruiz Veguilla, Pilar A Sáiz, Víctor Pérez
{"title":"Symptomatic networks in suicide attempt and reattempt: Relevance of psychiatric comorbidity.","authors":"Andres Pemau, Alejandro de la Torre-Luque, Carolina Marin-Martin, Marina Diaz-Marsa, Jorge Andreo-Jover, Wala Ayad-Ahmed, Maria Fe Bravo Ortiz, Maria Teresa Bobes-Bascarán, Manuel Canal-Rivero, Irene Canosa García, Ana Isabel Cebrià, Benedicto Crespo-Facorro, María Ángeles Boti, Matilde Elices, Ana González-Pinto, Iria Grande, Luis Jiménez-Treviño, Diego J Palao, Angela Palao-Tarrero, Carla Pérez-Guerra, Natalia Roberto, Miguel Ruiz Veguilla, Pilar A Sáiz, Víctor Pérez","doi":"10.1192/j.eurpsy.2024.1807","DOIUrl":"10.1192/j.eurpsy.2024.1807","url":null,"abstract":"<p><strong>Background: </strong>One of the most relevant risk factors for suicide is the presence of previous attempts. The symptomatic profile of people who reattempt suicide deserves attention. Network analysis is a promising tool to study this field.</p><p><strong>Objective: </strong>To analyze the symptomatic network of patients who have attempted suicide recently and compare networks of people with several attempts and people with just one at baseline.</p><p><strong>Methods: </strong>1043 adult participants from the Spanish cohort \"SURVIVE\" were part of this study. Participants were classified into two groups: single attempt group (n = 390) and reattempt group (n = 653). Different network analyses were carried out to study the relationships between suicidal ideation, behavior, psychiatric symptoms, diagnoses, childhood trauma, and impulsivity. A general network and one for each subgroup were estimated.</p><p><strong>Results: </strong>People with several suicide attempts at baseline scored significantly higher across all clinical scales. The symptomatic networks were equivalent in both groups of patients (p > .05). Although there were no overall differences between the networks, some nodes were more relevant according to group belonging.</p><p><strong>Conclusions: </strong>People with a history of previous attempts have greater psychiatric symptom severity but the relationships between risk factors show the same structure when compared with the single attempt group. All risk factors deserve attention regardless of the number of attempts, but assessments can be adjusted to better monitor the occurrence of reattempts.</p>","PeriodicalId":12155,"journal":{"name":"European Psychiatry","volume":"68 1","pages":"e4"},"PeriodicalIF":7.2,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11795427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142946935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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