Exposure and Health最新文献

{"title":"Associations of Perinatal Metal and Metalloid Exposures with Early Child Behavioral Development Over Time in the New Hampshire Birth Cohort Study.","authors":"Julia A Bauer, Megan E Romano, Brian P Jackson, David Bellinger, Susan Korrick, Margaret R Karagas","doi":"10.1007/s12403-023-00543-2","DOIUrl":"10.1007/s12403-023-00543-2","url":null,"abstract":"<p><p>Research on the neurodevelopmental effects of metal(loid)s has focused mainly on outcomes assessed at one time point, even though brain development progresses over time. We investigated biomarkers of perinatal exposure to metals and changes in child behavior over time. We followed 268 participants from the prospective New Hampshire Birth Cohort Study between birth and age 5 years. We measured arsenic (As), copper (Cu), manganese (Mn), lead (Pb), selenium (Se), and zinc (Zn) in toenails from 6-week-old infants. The Behavioral Symptoms Index (BSI), externalizing, and internalizing symptoms were assessed using the Behavior Assessment System for Children, 2nd edition (BASC-2) at ages 3 and 5 years. Multivariable linear regression was used to estimate associations of metals with behavior change, calculated as the difference in symptom raw scores between 3 and 5 years, in addition to the associations for symptom scores at 3 and 5 years separately. Sex-specific associations were also explored using stratified models and a sex-metal interaction term. Adjusted associations of metals and change in behavior varied by exposure and outcome. Each 1 μg/g increase in ln toenail Cu was associated with improved behavior between 3 and 5 years [BSI: <i>β</i> = - 3.88 (95%CI: - 7.12, - 0.64); Externalizing problems: <i>β</i> = - 2.20 (95%CI: - 4.07, - 0.33)]. Increasing Zn was associated with increased externalizing behavior over time (<i>β</i> = 3.42 (95%CI: 0.60, 6.25). Sex-stratified analyses suggested more pronounced associations among boys compared to girls. Perinatal exposure to metals may alter behavioral development between ages 3 and 5 years. Findings support the need for more research on associations between metals and neurodevelopment over longer time periods.</p>","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":null,"pages":null},"PeriodicalIF":6.7,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11060719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49507435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review of Groundwater Nitrate Pollution from Municipal Landfill Leachates: Implications for Environmental and Human Health and Leachate Treatment Technologies","authors":"Misbah Fida, Peiyue Li, S. Alam, Yuanhang Wang, Abel Nsabimana, Pratap Sundar Shrestha","doi":"10.1007/s12403-023-00624-2","DOIUrl":"https://doi.org/10.1007/s12403-023-00624-2","url":null,"abstract":"","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":null,"pages":null},"PeriodicalIF":6.7,"publicationDate":"2024-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139620432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Metal Exposure and Mitochondrial DNA Parameters and the Potential Mediation Effect of Oxidative Stress","authors":"Jing Xu, Meiduo Zhao, Xiaoyu Ge, Xiaolin Liu, Lanping Wei, Ang Li, Yayuan Mei, Guohuan Yin, Jingtao Wu, Qun Xu","doi":"10.1007/s12403-023-00623-3","DOIUrl":"https://doi.org/10.1007/s12403-023-00623-3","url":null,"abstract":"","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":null,"pages":null},"PeriodicalIF":6.7,"publicationDate":"2024-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139625226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exposure Characteristics and Human Health Risk Assessment of Herbicides in Water in a Typical Region of Northeastern China","authors":"Jun Ma, Wenjie Ren, Hongzhe Wang, Jiayin Song, Junfeng Jia, Hong Chen, Changyin Tan, Ying Teng","doi":"10.1007/s12403-023-00616-2","DOIUrl":"https://doi.org/10.1007/s12403-023-00616-2","url":null,"abstract":"","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":null,"pages":null},"PeriodicalIF":6.7,"publicationDate":"2024-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139625530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recycled Household Ash in Rice Paddies of Bangladesh for Sustainable Production of Rice Without Altering Grain Arsenic and Cadmium.","authors":"Yogesh Gupta, Mahmud Hossain, M Rafiqul Islam, Md Moyeed Hasan Talukder, Md Atiqur Rahman Khokon, Mohammad Mahir Uddin, Humayun Kabir, Manus Carey, Kathryn Ralphs, Natalia Valadares de Moraes, Andrew A Meharg, Caroline Meharg","doi":"10.1007/s12403-023-00539-y","DOIUrl":"10.1007/s12403-023-00539-y","url":null,"abstract":"<p><p>In Bangladesh most agronomic biomass (straw, husk, dried dung) is burnt for domestic cooking use. Consequently, the soil is continuously stripped of mineral nutrients and carbon (C) substrate. Here we investigate if recycling of household ash (ash) as fertilizer can sustainably improve soil fertility as well as minimise accumulation of toxic elements (As, Cd) in rice grain. Large scale field trials across two geographic regions (Barind, Madhupur) and two seasons (wet, dry) and with application of 3 fertiliser treatments (NPKS, ash, NPKS + ash) were conducted. At the end of each season, the impact of region*season*treatment on soil microbial comunities, rice yield, and grain quality (As, Cd, nutrient elements) was assessed. When compared to conventional field application rates of NPKS (control), application of ash boosted rice yield by circa. 20% in both regions during wet and dry season, with no effect on rice grain carcinogenic inorganic arsenic (iAs), dimethylarsonic acid (DMA) or cadmium (Cd), but with potential to increase zinc (Zn). For soil microbial communities, a significant region and season effect as well as correlation with elements in rice grain was observed, amongst these Cd, Zn, iAs and DMA. This study illustrates that application of ash can reduce the requirement for expensive chemical fertiliser, whilst at the same time increasing rice yield and maintaining grain quality, making farming in Bangladesh more sustainable and productive. The study also implies that the combined impact of region, season, and soil microbes determines accumulation of elements in rice grain.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s12403-023-00539-y.</p>","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":null,"pages":null},"PeriodicalIF":4.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10830805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42292460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Volatile Organic Compounds Detected in Amniotic Fluid of Women During Normal Pregnancy","authors":"R. Minet-Quinard, Nicolas Goncalves-Mendes, Denis Gallot, Bruno Pereira, C. Lambert, M. Brailova, L. Blanchon, D. Bouvier, Vincent Sapin","doi":"10.1007/s12403-023-00617-1","DOIUrl":"https://doi.org/10.1007/s12403-023-00617-1","url":null,"abstract":"","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":null,"pages":null},"PeriodicalIF":6.7,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138948595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cadmium Levels in Locally Produced and Imported Dark Chocolate in Lebanon","authors":"Z. Daher, Nathalie El Deghel, Rim Al Habahbeh, Mirna Azoury","doi":"10.1007/s12403-023-00614-4","DOIUrl":"https://doi.org/10.1007/s12403-023-00614-4","url":null,"abstract":"","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":null,"pages":null},"PeriodicalIF":6.7,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139009254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periconceptional and Prenatal Exposure to Metals and Extracellular Vesicle and Particle miRNAs in Human Milk: A Pilot Study.","authors":"Caitlin G Howe, David A Armstrong, Meghan E Muse, Diane Gilbert-Diamond, Jiang Gui, Anne G Hoen, Thomas J Palys, Roxanna L Barnaby, Bruce A Stanton, Brian P Jackson, Brock C Christensen, Margaret R Karagas","doi":"10.1007/s12403-022-00520-1","DOIUrl":"10.1007/s12403-022-00520-1","url":null,"abstract":"<p><p>Human milk is a rich source of microRNAs (miRNAs), which can be transported by extracellular vesicles and particles (EVPs) and are hypothesized to contribute to maternal-offspring communication and child development. Environmental contaminant impacts on EVP miRNAs in human milk are largely unknown. In a pilot study of 54 mother-child pairs from the New Hampshire Birth Cohort Study, we examined relationships between five metals (arsenic, lead, manganese, mercury, and selenium) measured in maternal toenail clippings, reflecting exposures during the periconceptional and prenatal periods, and EVP miRNA levels in human milk. 798 miRNAs were profiled using the NanoString nCounter platform; 200 miRNAs were widely detectable and retained for downstream analyses. Metal-miRNA associations were evaluated using covariate-adjusted robust linear regression models. Arsenic exposure during the periconceptional and prenatal periods was associated with lower total miRNA content in human milk EVPs (<i>P</i>_Bonferroni < 0.05). When evaluating miRNAs individually, 13 miRNAs were inversely associated with arsenic exposure, two in the periconceptional period and 11 in the prenatal period (<i>P</i>_Bonferroni < 0.05). Other metal-miRNA associations were not statistically significant after multiple testing correction (<i>P</i>_Bonferroni ≥ 0.05). Many of the arsenic-associated miRNAs are involved in lactation and have anti-inflammatory properties in the intestine and tumor suppressive functions in breast cells. Our findings raise the possibility that periconceptional and prenatal arsenic exposure may reduce levels of multiple miRNAs in human milk EVPs. However, larger confirmatory studies, which can apply environmental mixture approaches, evaluate potential effect modifiers of these relationships, and examine possible downstream consequences for maternal and child health and breastfeeding outcomes, are needed.</p>","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":null,"pages":null},"PeriodicalIF":6.7,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10707483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47859592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Evidence on the Effects of Endocrine-Disrupting Chemicals (EDCs) on Bone Growth and Health","authors":"Anna-Mariia Shulhai, Paola Palanza, Maria E. Street","doi":"10.1007/s12403-023-00607-3","DOIUrl":"https://doi.org/10.1007/s12403-023-00607-3","url":null,"abstract":"","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":null,"pages":null},"PeriodicalIF":6.7,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139225419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Follicular DNA Damage and Pesticide Exposure Among Latinx Children in Rural and Urban Communities","authors":"Cassandra Lepetit, Mohamed Gaber, Ke Zhou, Haiying Chen, Julia Holmes, Phillip Summers, Kim A. Anderson, R. P. Scott, Carey N. Pope, Kirstin Hester, P. Laurienti, S. Quandt, T. Arcury, Pierre-Alexandre Vidi","doi":"10.1007/s12403-023-00609-1","DOIUrl":"https://doi.org/10.1007/s12403-023-00609-1","url":null,"abstract":"","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":null,"pages":null},"PeriodicalIF":6.7,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139256082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}