Exposure and Health最新文献_第2页

The Mode of Action of Enniatins A and B is Mediated by Interaction with SOC Reservoirs (A) and Mitochondrial Permeability Transition Pore (B) enenniatins A和B的作用模式是通过与有机碳储层(A)和线粒体通透性过渡孔(B)的相互作用介导的。

3区环境科学与生态学

Exposure and Health Pub Date : 2023-11-07 DOI: 10.1007/s12403-023-00613-5

Nadia Pérez-Fuentes, Rebeca Alvariño, Amparo Alfonso, Jesús González-Jartín, Mercedes R. Vieytes, Luis M. Botana

引用次数: 0

Tempo-Spatial Variability and Health Risks of PM2.5 and Associated Metal(loid)s in Greater Cairo, Egypt 埃及大开罗地区PM2.5和相关金属(样物质)的时空变异和健康风险

3区环境科学与生态学

Exposure and Health Pub Date : 2023-11-06 DOI: 10.1007/s12403-023-00603-7

Waleed H. Shetaya, Asmaa El-Mekawy, Salwa K. Hassan

{"title":"Tempo-Spatial Variability and Health Risks of PM2.5 and Associated Metal(loid)s in Greater Cairo, Egypt","authors":"Waleed H. Shetaya, Asmaa El-Mekawy, Salwa K. Hassan","doi":"10.1007/s12403-023-00603-7","DOIUrl":"https://doi.org/10.1007/s12403-023-00603-7","url":null,"abstract":"Abstract Greater Cairo is one of the largest metropolitan areas in the world, yet the tempo-spatial trends of PM 2.5 and loaded metal(loid)s) in its atmosphere, and their potential health risks, are poorly understood. We investigated the air concentrations of PM 2.5 , and associated Al, As, Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb, V and Zn, in one urban and one industrial locations within Greater Cairo for one year in each location. Statistical analysis suggested that PM 2.5 and its chemical composition in Greater Cairo are more influenced by land-use and local activities rather than meteorological conditions. Both annual and daily levels of PM 2.5 were well above the WHO air quality guidelines, with annual averages of c. 37 and 56 µg m −3 , and daily maximums of 165 and 176 µg m −3 , in the urban and industrial areas, respectively. This indicates high probability of PM 2.5 inflicted short- and long-term health risks to the population of Greater Cairo. Health risk modelling indicated that the residents of Greater Cairo are facing high non-carcinogenic and carcinogenic risks (up to 47 and 28 times the recommended hazard indices, respectively) from the studied 12 metal(loid)s combined. Lead (Pb) was the highest single threat to the health of Greater Cairo residents amounting up to 56% and 83% of the total non-carcinogenic and carcinogenic risks, respectively. Nevertheless, most of the exposure to Pb originated from ingestion rather than inhalation which was marginal. For all elements combined, and for some other individual elements, inhalation was a significant route of exposure but only for non-carcinogenic risks. For carcinogenic risks, the contribution of inhalation to the total risk was negligible.","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":"24 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135678956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Latent Childhood Exposure to Mixtures of Metals and Neurodevelopmental Outcomes in 4–5-Year-Old Children Living in Spain 居住在西班牙的4 - 5岁儿童的潜在儿童接触金属混合物和神经发育结果

3区环境科学与生态学

Exposure and Health Pub Date : 2023-10-31 DOI: 10.1007/s12403-023-00610-8

L. Notario-Barandiaran, S. Díaz-Coto, N. Jimenez-Redondo, M. Guxens, M. Vrijheid, A. Andiarena, A. Irizar, I. Riaño-Galan, A. Fernández-Somoano, S. Llop, M. Lozano, M. R. Karagas, A. Meharg, M. Carey, C. Meharg, K. Ralphs, C. McCreanor, J. Vioque, P. Martinez-Camblor, A. J. Signes-Pastor

{"title":"Latent Childhood Exposure to Mixtures of Metals and Neurodevelopmental Outcomes in 4–5-Year-Old Children Living in Spain","authors":"L. Notario-Barandiaran, S. Díaz-Coto, N. Jimenez-Redondo, M. Guxens, M. Vrijheid, A. Andiarena, A. Irizar, I. Riaño-Galan, A. Fernández-Somoano, S. Llop, M. Lozano, M. R. Karagas, A. Meharg, M. Carey, C. Meharg, K. Ralphs, C. McCreanor, J. Vioque, P. Martinez-Camblor, A. J. Signes-Pastor","doi":"10.1007/s12403-023-00610-8","DOIUrl":"https://doi.org/10.1007/s12403-023-00610-8","url":null,"abstract":"Abstract Neurodevelopmental disorders are increasing globally, and metal exposure may play a significant role as an environmental factor. This cross-sectional study aimed to identify metal mixture patterns and assess their impact on children’s neurodevelopment. Data from 962 children (aged 4–5 years) participating in the Spanish INMA cohort study were analysed. Urinary metal concentrations (cobalt (Co), copper (Cu), molybdenum (Mo), selenium (Se), lead (Pb), zinc (Zn), and arsenic speciation) were used as exposure biomarkers. Principal component analysis (PCA) revealed four latent exposure variables representing uncorrelated metal mixture patterns. Linear regression analyses examined the associations between these variables and children’s neuropsychological functions assessed through the McCarthy Scales of Children’s Abilities. The first latent exposure variable (Cu, Se, Pb, Zn) and the second (inorganic arsenic, monomethylarsonic acid) showed negative associations with verbal executive function ( ß = − 1.88, 95% confidence interval (CI) = − 3.17 to − 0.59) and gross motor function ( ß = − 1.41, 95% CI = − 2.36 to − 0.46), respectively. Conversely, the third variable (Mo, Co) and the fourth (arsenobetaine) exhibited positive associations with visual and verbal span functions ( ß = 1.14, 95% CI = 0.16 to 2.12) and fine motor function ( ß = 1.01, 95% CI = 0.11 to 1.92), respectively. This study suggests that even relatively low levels of metal latent exposures, notably inorganic arsenic and a mixture of metals including Pb, adversely affect children’s neuropsychological development function scores, while exposure to arsenobetaine and a mixture of Co and Mo has a positive impact.","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":"2003 17","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135813130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multi-metal Exposure and Liver Function in Elderly with Diabetes Mellitus: A Cross-Sectional Study in Eastern China 中国东部地区老年糖尿病患者多金属暴露与肝功能的横断面研究

3区环境科学与生态学

Exposure and Health Pub Date : 2023-10-19 DOI: 10.1007/s12403-023-00598-1

Jiujing Lin, Jia Li, Huichen Yao, Jinjie He, Xiangsheng Xue, Hengxia Zhao, Chenyang Hou, Xiaomei Li, Qingzhi Hou

引用次数: 0

Dietary Exposure to Dicofol, Endosulfan, and Naturally Produced Halogenated Bipyrroles: 24-hr Food Duplicate Surveys from Five Prefectures in Japan 饮食中暴露于三敌畏、硫丹和天然产生的卤代双咯:来自日本五个县的24小时食物重复调查

3区环境科学与生态学

Exposure and Health Pub Date : 2023-10-17 DOI: 10.1007/s12403-023-00604-6

Yukiko Fujii, Kouji H. Harada, Yoshihisa Kato, Osamu Kimura, Tetsuya Endo, Koichi Haraguchi

引用次数: 0

Exposure, Distribution, and Ecological Risk of Four New Bisphenol Analogs in the Typical Lake Region of Taihu Lake 四种新型双酚类似物在太湖典型湖区的暴露、分布及生态风险

3区环境科学与生态学

Exposure and Health Pub Date : 2023-10-10 DOI: 10.1007/s12403-023-00608-2

Ying Han, Yuxuan Liu, Xiaolong Rong, Mingxin Wang, Yingang Xue, Hao Dai, Haixia Jiang

引用次数: 0

Applications of Mycotoxin Biomarkers in Human Biomonitoring for Exposome-Health Studies: Past, Present, and Future 霉菌毒素生物标志物在人体暴露体健康研究生物监测中的应用:过去、现在和未来

3区环境科学与生态学

Exposure and Health Pub Date : 2023-10-09 DOI: 10.1007/s12403-023-00595-4

Iyiola O. Owolabi, Kawisara Siwarak, Brett Greer, Andreja Rajkovic, Chiara Dall’asta, Nitsara Karoonuthaisiri, Umaporn Uawisetwathana, Christopher T. Elliott, Awanwee Petchkongkaew

{"title":"Applications of Mycotoxin Biomarkers in Human Biomonitoring for Exposome-Health Studies: Past, Present, and Future","authors":"Iyiola O. Owolabi, Kawisara Siwarak, Brett Greer, Andreja Rajkovic, Chiara Dall’asta, Nitsara Karoonuthaisiri, Umaporn Uawisetwathana, Christopher T. Elliott, Awanwee Petchkongkaew","doi":"10.1007/s12403-023-00595-4","DOIUrl":"https://doi.org/10.1007/s12403-023-00595-4","url":null,"abstract":"Abstract This publication reviews the state-of-the-art human biological monitoring (HBM) of mycotoxin biomarkers in breast milk, plasma, serum, and whole blood samples with a focus on the past two decades (2000–2011 and 2011–2021). Three aspects have been analyzed and summarized: (a) the biomarkers detected and their levels found, (b) the analytical methodologies developed and employed, and (c) the exposome concept and the significance of omics tools. From the literature reviewed, aflatoxins (AFs) and ochratoxin A (OTA) in human breast milk, plasma and serum were the most widely studied mycotoxin biomarkers for HBM. Regarding analytical methodologies, a clear increase in the development and implementation of mass spectrometry methods for simultaneous determination of multiple mycotoxins was observed. For this purpose, use of liquid chromatography (LC) methodologies, especially when coupled with tandem mass spectrometry (MS/MS) or high-resolution mass spectrometry (HRMS) has grown substantially and are now the methods of choice. A high percentage of the samples analyzed for various mycotoxins in the literature reviewed were found to contain biomarkers, demonstrating a combination of targeted sampling and high levels of human exposure to mycotoxins within the target populations. Also, most HBM investigations only examined exposure to one or a few mycotoxins at a given period. Human exposome studies undertake a wider evaluation of the exposure as part of epidemiological studies through the discovery of novel biomarkers that exist as potential indicators of environmental influences on human health. However, guidelines are required for analytical method validation, as well as algorithms to establish the relationship between the levels of biomarkers detected in human biofluids and mycotoxin intake.","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135093622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exposure to Environmental Chemicals and Human Bone Health; A Systematic Review and Meta-Analysis 环境化学品暴露与人体骨骼健康系统回顾和荟萃分析

3区环境科学与生态学

Exposure and Health Pub Date : 2023-10-04 DOI: 10.1007/s12403-023-00596-3

Sadegh Baradaran Mahdavi, Sara Zamani, Roya Riahi, Ensiyeh Taheri, Babak Vahdatpour, Fariborz Sharifianjazi, Roya Kelishadi

引用次数: 0

Correction: Potential Factors Associated with the Blood Metal Concentrations of Reproductive-Age Women in Taiwan 更正:台湾育龄妇女血金属浓度之潜在因素

3区环境科学与生态学

Exposure and Health Pub Date : 2023-10-02 DOI: 10.1007/s12403-023-00606-4

Tsung-Ho Ying, Chun-Jui Huang, Chia-Jung Hsieh, Pei-Ju Wu, Chang-Ching Yeh, Ping-Kun Hung, Wei-Hsiang Chang, Meng-Hsing Wu, Hsin Hung, Jung-Wei Chang, Chen-Tai Wang, Rachelle D. Arcega, Trias Mahmudiono, Ching-Chang Lee, Hsiu-Ling Chen

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Quantifying the Health Risks of PM2.5-Bound Heavy Metals for Rural Populations with Different Energy Use Types During the Heating Season 采暖季不同能源利用类型农村人口pm2.5结合重金属健康风险量化

3区环境科学与生态学

Exposure and Health Pub Date : 2023-09-27 DOI: 10.1007/s12403-023-00590-9

Wenju Wang, Mingya Wang, Mingshi Wang, Xuechun Zhang, Qiao Han, Chun Chen, Dan Liu, Qinqing Xiong, Chunhui Zhang

引用次数: 0