Exposure and Health最新文献_第10页

Groundwater Quality for Drinking and Non-Carcinogenic Risk of Nitrate in Urban and Rural Areas of Fereidan, Iran 伊朗Fereidan城市和农村地区饮用地下水质量和硝酸盐的非致癌风险

IF 6.7 3区环境科学与生态学

Exposure and Health Pub Date : 2022-12-02 DOI: 10.1007/s12403-022-00525-w

V. Amiri, N. Sohrabi, Peiyue Li, Fahimeh Amiri

引用次数: 12

Effect of Mixture of Heavy Metals on Metabolic Syndrome and Its Components in Individuals ≥ 18 Years of Age: From Big Data to Molecular Mechanisms Involved 混合重金属对个体代谢综合征及其成分的影响 ≥ 18岁：从大数据到分子机制

IF 6.7 3区环境科学与生态学

Exposure and Health Pub Date : 2022-12-02 DOI: 10.1007/s12403-022-00523-y

Hai Duc Nguyen, Hojin Oh, Min-Sun Kim

引用次数: 4

Alterations in Microbial-Associated Fecal Metabolites in Relation to Arsenic Exposure Among Infants. 婴儿中与砷暴露有关的微生物相关粪便代谢物的改变。

IF 6.7 3区环境科学与生态学

Exposure and Health Pub Date : 2022-12-01 Epub Date: 2022-02-03 DOI: 10.1007/s12403-022-00468-2

Margaret R Karagas, Susan McRitchie, Anne G Hoen, Cindy Takigawa, Brian Jackson, Emily R Baker, Juliette Madan, Susan J Sumner, Wimal Pathmasiri

{"title":"Alterations in Microbial-Associated Fecal Metabolites in Relation to Arsenic Exposure Among Infants.","authors":"Margaret R Karagas, Susan McRitchie, Anne G Hoen, Cindy Takigawa, Brian Jackson, Emily R Baker, Juliette Madan, Susan J Sumner, Wimal Pathmasiri","doi":"10.1007/s12403-022-00468-2","DOIUrl":"10.1007/s12403-022-00468-2","url":null,"abstract":"In utero and early life exposure to inorganic arsenic (iAs) alters immune response in experimental animals and is associated with an increased risk of infant infections. iAs exposure is related to differences in the gut microbiota diversity, community structure, and the relative abundance of individual microbial taxa both in laboratory and human studies. Metabolomics permits a direct measure of molecular products of microbial and host metabolic processes. We conducted NMR metabolomics analysis on infant stool samples and quantified the relative concentrations of 34 known microbial-related metabolites. We examined these metabolites in relation to both in utero and infant log2 urinary total arsenic concentrations (utAs, the sum of iAs and iAs metabolites) collected at approximately 6 weeks of age using linear regression models, adjusted for infant sex, age at sample collection, type of delivery (vaginal vs. cesarean section), feeding mode (breast milk vs. any formula), and specific gravity. Increased fecal butyrate (b = 214.24), propionate (b = 518.33), cholate (b = 8.79), tryptophan (b= 14.23), asparagine (b = 28.80), isoleucine (b = 65.58), leucine (b = 95.91), malonate (b = 50.43), and uracil (b = 36.13), concentrations were associated with a doubling of infant utAs concentrations (p< 0.05). These associations were largely among infants who were formula fed. No clear associations were observed with maternal utAs and infant fecal metabolites. Metabolomic analyses of infant stool samples lend further evidence that the infant gut microbiota is sensitive to As exposure, and these effects may have functional consequences.","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":"14 4","pages":"941-949"},"PeriodicalIF":6.7,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918239/pdf/nihms-1818701.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10704067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Heavy Metal(loid) Body Burden in Environmentally Exposed Children With and Without Internalizing Behavior Problems. 有和没有内化行为问题的环境暴露儿童的重金属（类）身体负担

IF 4.5 3区环境科学与生态学

Exposure and Health Pub Date : 2022-12-01 Epub Date: 2022-02-02 DOI: 10.1007/s12403-022-00469-1

Kristina M Zierold, John V Myers, Guy N Brock, Charlie H Zhang, Clara G Sears, Lonnie Sears

{"title":"Heavy Metal(loid) Body Burden in Environmentally Exposed Children With and Without Internalizing Behavior Problems.","authors":"Kristina M Zierold, John V Myers, Guy N Brock, Charlie H Zhang, Clara G Sears, Lonnie Sears","doi":"10.1007/s12403-022-00469-1","DOIUrl":"10.1007/s12403-022-00469-1","url":null,"abstract":"The prevalence of internalizing behavior disorders in children is increasing. Reasons for increasing anxiety and depression include several factors with a less studied consideration being the potential neurotoxic effects of environmental exposures. One group at risk for environmental exposures is children living near coal-burning power plants with coal ash storage facilities. Multivariate logistic regression was used to assess the relationship between metal(loid) exposures and internalizing behaviors in children aged 6-14 years. Metal(loid)s in nail samples were determined by Proton-Induced X-ray Emission and internalizing behavior problems were obtained from the parent ratings on the Child Behavior Checklist. Results indicated that concentrations of metal(loid)s in nails differ between children with internalizing behaviors and without internalizing behaviors. Logistic regression models suggested that exposure to zinc and imputed zirconium were associated with internalizing behaviors in children. However, when a sex-metal(loid) interaction term was included, none of the metal(loid)s were associated with internalizing behaviors indicating a role of sex differences in neurotoxicity with zinc and copper showing effects only for males. In all models, greater exposure to traffic was associated with internalizing behaviors. Zinc has previously been shown to increase risk for mental health problems, while zirconium has received less attention. Out findings indicate that environmental exposures of zinc and zirconium deserve further attention in studies of childhood internalizing disorders.","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":"14 1","pages":"903-914"},"PeriodicalIF":4.5,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11185413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41832258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydrochemical Background Levels and Threshold Values of Phreatic Groundwater in the Greater Xi’an Region, China: Spatiotemporal Distribution, Influencing Factors and Implication to Water Quality Management 大西安地区潜水地下水水化学背景水平与阈值的时空分布、影响因素及其对水质管理的启示

IF 6.7 3区环境科学与生态学

Exposure and Health Pub Date : 2022-11-14 DOI: 10.1007/s12403-022-00521-0

Yuhan Zhou, Jianhua Wu, Xingyu Gao, Wenyu Guo, Wenqian Chen

引用次数: 9

Prenatal Exposure to Phthalates and Bisphenols and Childhood Kidney Function: A Prospective Cohort Study 产前接触邻苯二甲酸盐和双酚类物质与儿童肾功能的前瞻性队列研究

IF 6.7 3区环境科学与生态学

Exposure and Health Pub Date : 2022-11-12 DOI: 10.1007/s12403-022-00517-w

Chalana M. Sol, S. Santos, K. Kannan, V. Jaddoe, L. Trasande

引用次数: 1

Microplastics Pollution and Risk Assessment in Selected Surface Waters of the Wei River Plain, China 渭河平原部分地表水微塑料污染及其风险评价