Folia medica Cracoviensia最新文献_第6页

Anatomical features of the mandibular canal and their clinical significance - review of literature. 下颌管的解剖特征及其临床意义--文献综述。

Folia medica Cracoviensia Pub Date : 2023-10-30 DOI: 10.24425/fmc.2023.147220

Janusz Skrzat, Wojciech Ryniewicz, Grzegorz Goncerz, Magdalena Kozerska

引用次数: 0

Treatment options for oropharyngeal carcinoma - An umbrella review. 口咽癌的治疗方案 - 综述。

Folia medica Cracoviensia Pub Date : 2023-10-30 DOI: 10.24425/fmc.2023.147217

Dawid Plutecki, Elżbieta Szczepanek, Małgorzata Szczepanek, Ameen Nasser, Paweł Hajdyła, Andrzej Wrona

{"title":"Treatment options for oropharyngeal carcinoma - An umbrella review.","authors":"Dawid Plutecki, Elżbieta Szczepanek, Małgorzata Szczepanek, Ameen Nasser, Paweł Hajdyła, Andrzej Wrona","doi":"10.24425/fmc.2023.147217","DOIUrl":"10.24425/fmc.2023.147217","url":null,"abstract":"Introduction: Our umbrella review aimed to summarize and revisit the evidence from all of the meta-analyses and systematic reviews regarding the treatments of oropharyngeal squamous cell carcinoma (OPSCC).Materials and methods: Major medical databases such as PubMed, Scopus, Embase, Web of Science, Google Scholar, Cochrane Library, BIOSIS, and EBSCO were searched. The overall search process was conducted in 3 stages.Results: Finally, a total of 28 studies met the inclusion criteria and were included in this study. Out of those 28 meta-analyses, a total of 315 primary studies were screened in order to extract the data and perform the statistical analysis. In total, data from 22,619 patients was analyzed.Conclusion: The main objective of the present umbrella review was to summarize and analyze all of the evidence-based data provided by numerous meta-analyses and systematic reviews regarding the treatment of OPSCC. Our study delivers the most up-to-date and evidence-based results regarding the different therapeutic modalities of this malignancy in one concise review, making it the ultimate tool for physicians treating OPSCC.","PeriodicalId":12106,"journal":{"name":"Folia medica Cracoviensia","volume":"63 3","pages":"103-124"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139680963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum level of lactadherin (MFGE8) in inflamatory bowel disease. 炎症性肠病的血清乳粘连素（MFGE8）水平。

Folia medica Cracoviensia Pub Date : 2023-10-30 DOI: 10.24425/fmc.2023.147212

Kamil Kozioł, Danuta Owczarek, Dorota Cibor, Małgorzata Zwolińska-Wcisło

{"title":"Serum level of lactadherin (MFGE8) in inflamatory bowel disease.","authors":"Kamil Kozioł, Danuta Owczarek, Dorota Cibor, Małgorzata Zwolińska-Wcisło","doi":"10.24425/fmc.2023.147212","DOIUrl":"10.24425/fmc.2023.147212","url":null,"abstract":"Objective: Evaluation of serum lactadherin level, its correlation with disease activity and certain biochemical parameters in IBD patients.Methods: The study involved adult IBD patients, comprising 50 with ulcerative colitis (UC), 68 with Crohn's disease (CD), and 29 healthy controls.Results: The MFGE8 median concentration was significantly higher in UC versus controls (1914.54 vs. 1392.21; p = 0.017), but not in CD. The median MFGE8 levels in UC and CD patient groups didn't significantly differ. There was a significant inverse correlation between MFGE8 and CRP (r = -0.283; p = 0.044) and fibrinogen (r = -0.362, p = 0.017) in UC. In active UC, MFGE8 median concentration was higher versus controls (1974.36 vs. 1392.21; p = 0.04) and negatively correlated with CRP (r = -0.482; p = 0.005), WBC (r = -0.391; p = 0.027), and fibrinogen (r = -0.473; p = 0.015). Inactive UC showed negative correlation only with fibrinogen (r = -0.567; p = 0.018). No correlations were found with disease activity measured using appropriate scales, age, BMI, or gender.Conclusions: Active UC patients show higher MFGE8 levels. These increase inversely with inflammatory markers (CRP, WBC, fibrinogen) in active UC, but not in CD.","PeriodicalId":12106,"journal":{"name":"Folia medica Cracoviensia","volume":"63 3","pages":"15-29"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139680872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The autonomic nervous system in anorexia nervosa - an implication for the fat tissue. 神经性厌食症的自律神经系统--对脂肪组织的影响。

Folia medica Cracoviensia Pub Date : 2023-10-30 DOI: 10.24425/fmc.2023.147215

Andrzej Boryczko, Kamil Skowron, Magdalena Kurnik-Łucka, Krzysztof Gil

{"title":"The autonomic nervous system in anorexia nervosa - an implication for the fat tissue.","authors":"Andrzej Boryczko, Kamil Skowron, Magdalena Kurnik-Łucka, Krzysztof Gil","doi":"10.24425/fmc.2023.147215","DOIUrl":"10.24425/fmc.2023.147215","url":null,"abstract":"Eating disorders are a heterogeneous group of diseases affecting mainly young people in developed countries. Among them, anorexia nervosa (AN) is the one with the highest mortality, up to five times higher compared to healthy individuals. The etiology of this medical condition is complex and still un- certain. However, disturbances of the autonomic nervous system (ANS) and increased lipolysis resulting in a decrease of the adipose tissue volume are common findings among AN patients. Since ANS is directly connected to adipocyte tissue, thus significantly affecting the body's metabolic homeostasis, we suspect that this relationship may be a potential pathophysiological underpinning for the development of AN. In this narrative review, we have analyzed scientific reports on ANS activity in AN considering different phases of the disease in humans as well as animal models. Due to the different effects of the disease itself on the ANS as well as specific variations within animal models, the common feature seems to be dysregulation of its function without the identification of one universal pattern. Nonetheless, higher norepinephrine concentrations have been reported in adipocyte tissue, suggesting local dominance of the sym- pathetic nervous system. Further studies should explore in depth the modulation of sympathetic in adipose tissue factor and help answer key questions that arise during this brief narrative review.","PeriodicalId":12106,"journal":{"name":"Folia medica Cracoviensia","volume":"63 3","pages":"75-90"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139680938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The significance of nutritional strategies in patients with inflammatory bowel disease in the context of malnutrition and the development of malnourished obesity. 145912

Folia medica Cracoviensia Pub Date : 2023-07-30 DOI: 10.24425/fmc.2023.145912

Agnieszka Dąbek, Olga Kaczmarczyk, Tomasz Dziubyna, Agnieszka Piątek-Guziewicz, Małgorzata Zwolińska-Wcisło

{"title":"The significance of nutritional strategies in patients with inflammatory bowel disease in the context of malnutrition and the development of malnourished obesity.","authors":"Agnieszka Dąbek, Olga Kaczmarczyk, Tomasz Dziubyna, Agnieszka Piątek-Guziewicz, Małgorzata Zwolińska-Wcisło","doi":"10.24425/fmc.2023.145912","DOIUrl":"10.24425/fmc.2023.145912","url":null,"abstract":"Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis, despite the increasing incidence, still do not have a specific etiology. Diet seems to be an important factor, modifying the occurrence of the disease and its course. Diet can affect the symptoms of IBD both directly, e.g., by alleviating diarrhea, bloating and constipation, and indirectly by shaping the microbiota. Bacterial metabolites produced under the influence of supplied nutrients may contribute to the modulation of pro- and anti-inflammatory pathways, depending on the diet used. So far, IBD has been associated with weight loss and malnutrition. In recent years, a trend of sarcopenic obesity with concomitant malnutrition has been observed. The new phenomenon is called malnubesity. This work aims to review the most commonly used diets in IBD in order to evaluate them in terms of alleviating ailments, but also maintaining proper nutritional status and lack of obesity. Low-fiber, low FODMAPs, Mediterranean diet and Crohn's Disease Exclusion Diet diet were considered. We assume that diet is modifiable factor that is related to nutritional status and healthy body weight. In addition, the current knowledge on the relationship between nutrition strategies, obesity and IBD will be demonstrated.","PeriodicalId":12106,"journal":{"name":"Folia medica Cracoviensia","volume":" ","pages":"41-56"},"PeriodicalIF":0.0,"publicationDate":"2023-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47545664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Experimental therapies in Irritable Bowel Syndrome. 肠易激综合征的实验治疗。

Folia medica Cracoviensia Pub Date : 2023-07-11 DOI: 10.24425/fmc.2021.137209

J. Włodarczyk, Patrycja Szałwińska, A. Waśniewska, J. Fichna

引用次数: 1

145913 145913

Folia medica Cracoviensia Pub Date : 2023-05-11 DOI: 10.24425/fmc.2023.145913

引用次数: 0

145910 one hundred and forty-five thousand nine hundred and ten

Folia medica Cracoviensia Pub Date : 2023-05-11 DOI: 10.24425/fmc.2023.145910

引用次数: 0

145919 145919

Folia medica Cracoviensia Pub Date : 2023-05-11 DOI: 10.24425/fmc.2023.145919

{"title":"145919","authors":"","doi":"10.24425/fmc.2023.145919","DOIUrl":"https://doi.org/10.24425/fmc.2023.145919","url":null,"abstract":"Prevalence of metabolic syndrome (MetS) and its components is a growing issue, including pediatric populations. However, because of many definitions used, it is difficult to assess the true frequency of these problems. The aim of this study was to assess the prevalence of MetS and its components as well as the frequency of problems with inadequate nutritional status among adolescents. One hundred ninety-six teenagers aged 15-18 years, living in Krakow and its vicinity were examined including measurement of blood pressure, anthropometric parameters and blood levels of cholesterol and glucose. The prevalence of MetS was low and varied from 0.5% to 2.0% depending on the definition. Based on Cook's definition of MetS, the most common components were hypertension (12.8%) and hypertriglyceridemia (12.8%). Improper body weight (based on BMI) was found in 23.5% of adolescents, including 5.1% underweight, and 18.4% overweight or obese. According to the body fat percentage (BF%), 45.8% of the boys were underfat and 6.3% had too much body fat, while only 4% of the girls were below the BF% reference values and 15% above. All girls and 86.5% of boys had too low total body water. In conclusion, the prevalence of metabolic syndrome in population of Krakow adolescents was relatively low, but more than 12% of the adolescents had a hypertension or hypertriglyceridemia. Based on BMI most of adolescents were found to have adequate body weight, but examination of fat content in the body high prevalence of underfat was observed, especially among boys.","PeriodicalId":12106,"journal":{"name":"Folia medica Cracoviensia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45004715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

145917 145917

Folia medica Cracoviensia Pub Date : 2023-05-11 DOI: 10.24425/fmc.2023.145917

{"title":"145917","authors":"","doi":"10.24425/fmc.2023.145917","DOIUrl":"https://doi.org/10.24425/fmc.2023.145917","url":null,"abstract":"Drug-abuse detection tests are becoming increasingly commonplace in patient care today and provide a rapid and effective method for identifying illicit substances. Occasionally, they may yield a positive result, indicating the presence of a substance, even though the individual has not consumed the suspected drug what sometimes can significantly impact both medical and legal decisions. The study outlines the substances that can lead to false-positive drug test results for amphetamines, cannabinoids, and benzodiazepines. The study's findings have revealed pivotal insights for patients receiving chronic treatment and their primary care physicians. Notably, amphetamine assays appear to be most prone to cross-reactivity with other substances. The beta-blocker group of medications, confirmed by various studies to interfere with amphetamine assays, could pose a substantial challenge in drug screening given its widespread use. Efavirenz also warrants mention, as it frequently triggers positive results for both benzodiazepine and cannabinoid assays among its users. This research helps highlight new areas for further investigation and aims to guide clinicians in their daily practice, especially when interpreting questionable positive drug-abuse test results. This comprehensive review serves as a valuable resource for clinicians to navigate false-positive scenarios effectively and maintain the highest standard of patient care.","PeriodicalId":12106,"journal":{"name":"Folia medica Cracoviensia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48513969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0