European Radiology最新文献

{"title":"Estimating the rate of acute adverse reactions to non-ionic low-osmolar contrast media: a systematic review and meta-analysis.","authors":"Yuguo Wei, Xinchao Jiang, Mark Hibberd, Alexis Sampedro, Jeannette Rautenbach","doi":"10.1007/s00330-025-11526-z","DOIUrl":"10.1007/s00330-025-11526-z","url":null,"abstract":"<p><strong>Objectives: </strong>This systematic review and meta-analysis aimed to assess and compare acute adverse reactions (AAR) rates among non-ionic low-osmolar contrast media (LOCM), examining administration routes and severity-specific impact on AAR rates.</p><p><strong>Materials and methods: </strong>A PubMed and Cochrane Library search identified studies published between January 1989 and March 2024. Inclusion criteria focused on studies with > 100 adult patients who received intra-arterial or intravenous LOCM (iobitridol, iohexol, iomeprol, iopamidol, iopromide, and ioversol). Duplicate reports and studies with insufficient information were excluded. Data extraction and quality assessment followed PRISMA guidelines and the Newcastle Ottawa Scale. Statistical analyses were performed using R software, including random effects, meta-regression, and sub-group analysis.</p><p><strong>Results: </strong>After excluding duplicates and non-compliant studies, 32 peer-reviewed articles of initially 6701 identified studies, were included in the final analysis. The pooled overall AAR rate was 0.73%, with ioversol showing the lowest rate (0.34%). From all studies, pooled rates (random effects model) of moderate and severe AARs were 0.10% and 0.014% (p < 0.01), with the lowest rates for iohexol (0.05% and 0.008%, respectively). The highest overall, moderate, and severe AAR rates were seen with iomeprol (1.38%, 0.27%, and 0.040%, respectively). LOCM type (p < 0.0001), study design (p = 0.0001), and injection route (p = 0.034) significantly influenced the overall AAR rate. In contrast, the study center number (p = 0.698), the country where the study was performed (p = 0.808), and the type of reaction (hypersensitivity vs hypersensitivity plus physiological reactions; p = 0.178) did not.</p><p><strong>Conclusion: </strong>AAR rates were low but indicated significant differences between LOCM; iohexol and ioversol demonstrated the overall most favorable safety profiles.</p><p><strong>Key points: </strong>Question Knowledge about AAR is crucial for patient safety, but comprehensive data on the safety profiles of non-ionic LOCM is lacking. Findings Ioversol showed the lowest overall AAR rate; iohexol demonstrated the lowest moderate/severe AAR. Study design, LOCM type, and injection route influenced AAR rates. Clinical relevance This meta-analysis provides evidence for differences in non-ionic LOCM safety profiles, particularly for moderate and severe AARs. These can guide clinicians in selecting contrast agents, aiming to further reduce risks, and improve patient safety in diagnostic imaging.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":"6240-6249"},"PeriodicalIF":4.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to the Letter to the Editor: \"An unenhanced 3D-FLAIR sequence using long repetition time and constant flip angle to image endolymphatic hydrops\".","authors":"Menglong Zhao, Huaili Jiang, Shujie Zhang, Kai Liu, Lei Zhou, Di Wu, Xixi Wen, Junpu Hu, Xuan Wang, Zhuang Liu, Yan Sha, Mengsu Zeng","doi":"10.1007/s00330-025-11537-w","DOIUrl":"10.1007/s00330-025-11537-w","url":null,"abstract":"","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":"6610-6611"},"PeriodicalIF":4.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CT evaluation of response in locally advanced gastric cancer. Is it time for a change?","authors":"Ramiro J Méndez","doi":"10.1007/s00330-025-11600-6","DOIUrl":"10.1007/s00330-025-11600-6","url":null,"abstract":"","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":"6466-6468"},"PeriodicalIF":4.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143973837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The plaque factor: Can coronary CT angiography plaque analysis link stenosis and ischemia?","authors":"Dominika Suchá","doi":"10.1007/s00330-025-11616-y","DOIUrl":"10.1007/s00330-025-11616-y","url":null,"abstract":"","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":"6268-6270"},"PeriodicalIF":4.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of contrast-enhanced cone-beam breast CT, MRI, and mammography for breast cancer characterization.","authors":"Yue Ma, Yafei Wang, Yuwei Zhang, Keyi Bian, Yueqiang Zhu, Aidi Liu, Haijie Li, Lu Yin, Hong Lu, Zhaoxiang Ye","doi":"10.1007/s00330-025-11568-3","DOIUrl":"10.1007/s00330-025-11568-3","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the consistency of contrast-enhanced cone-beam breast CT (CE-CBBCT), MRI and mammography regarding characterization of breast cancer.</p><p><strong>Methods: </strong>In this retrospective study, patients with breast cancer who underwent preoperative CE-CBBCT, MRI, and mammography between January 2017 and July 2022 were enrolled. Three experienced radiologists independently interpreted the characteristics of breast lesions on each imaging mode referring to BI-RADS, with a 4-week wash-out period. One of the three radiologists reviewed the CE-CBBCT images 4 weeks after the initial evaluation. Cross-modality consistency was calculated by Cohen's Kappa based on majority report. Inter-and intra-reader agreement were assessed using Fleiss and Cohen's Kappa, respectively. The association between imaging factors and consistency levels was analyzed using chi-square and Mann-Whitney U test.</p><p><strong>Results: </strong>A total of 214 malignant lesions identified in 207 patients were enrolled. CE-CBBCT showed almost perfect agreement with MRI on lesion type identification (Kappa = 0.865, 95% CI: 0.802-0.928), but fair agreement with mammography (Kappa = 0.287, 95% CI: 0.205-0.369). CE-CBBCT showed substantial agreement on characterization with MRI for both mass (Kappa = 0.752-0.824) and non-mass enhancement (NME) (Kappa = 0.702-0.729), and non-contrast-enhanced CBBCT (NCE-CBBCT) showed substantial agreement with mammography for calcification (Kappa = 0.717-0.777). Inter- (Kappa = 0.611-0.738) and intra-reader (Kappa = 0.757-0.887) agreement were substantial on CE-CBBCT interpretation. There was no statistically significant difference in imaging factors between different consistency levels (all p > 0.05).</p><p><strong>Conclusions: </strong>CE-CBBCT showed high consistency on mass and NME characterization with MRI, and on calcification with mammography, indicating that CE-CBBCT could combine morphology, hemodynamic and calcification features, and the corresponding descriptors have the feasibility to describe CE-CBBCT characteristics of breast cancer.</p><p><strong>Key points: </strong>Question Contrast-enhanced cone-beam breast CT (CE-CBBCT) is widely used in the diagnosis and assessment of breast cancer, but there is no standardized lexicon for image interpretation. Findings CE-CBBCT showed high consistency and comparable reproducibility with MRI and mammography for characterizing breast cancer lesions. Clinical relevance The findings prove that CE-CBBCT could combine morphology, hemodynamic, and calcification features and provide support for the feasibility of applying the BI-RADS descriptors of MRI and mammography to interpret contrast-enhanced cone-beam breast CT images in clinic.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":"6398-6409"},"PeriodicalIF":4.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Volumetric and diffusion MRI longitudinal patterns in brain metastases after laser interstitial thermal therapy.","authors":"Francesco Sanvito, Jingwen Yao, Gianluca Nocera, Guowen Shao, Zexi Wang, Nicholas S Cho, Ashley Teraishi, Catalina Raymond, Kunal Patel, Nader Pouratian, Richard G Everson, Isaac Yang, Noriko Salamon, Won Kim, Benjamin M Ellingson","doi":"10.1007/s00330-025-11587-0","DOIUrl":"10.1007/s00330-025-11587-0","url":null,"abstract":"<p><strong>Objective: </strong>To characterize MRI changes of brain metastases (BM) following laser interstitial thermal therapy (LITT), particularly in lesions exhibiting durable response or early progression.</p><p><strong>Materials and methods: </strong>Longitudinal scans from patients with LITT-treated BM were retrospectively analyzed. Treatment response was categorized as durable response, long-term disease control (i.e., stable at 1 year), stable disease < 1 year, or progression < 1 year. Volumetric and diffusion MRI changes after LITT were analyzed for each subregion (contrast-enhancing, central non-enhancing, whole lesion). Volumetric changes were modeled with bi-exponential fits in responding lesions and progressors.</p><p><strong>Results: </strong>295 MRI scans from 47 lesions across 42 patients (57.8 ± 14.3 years old, males:females 21:21) were analyzed. Overall, the post-LITT scan showed a lesion enlargement (p < 0.0001 for all subregions), more pronounced in the contrast-enhancing (CE) component (median = +77%, p < 0.0001), and a reduction in the apparent diffusion coefficient (ADC) (p < 0.001), especially in the central non-CE component (median = -224 × 10^-⁶ mm²/s, p < 0.0001), with no significant differences between responders and progressors. Based on mathematical modeling, the responding lesions shrank to half of the post-LITT size after 79.83 days (median \"pseudo-half-life\"), and the progressing lesions shrank for a median of 27 days (median time-to-growth) before regrowing. The estimated optimal timepoints for follow-up scans were 23 days and 125 days, yielding accuracy/specificity/sensitivity 0.82/1.0/0.55 in identifying progressing lesions (p < 0.01).</p><p><strong>Conclusion: </strong>BM typically exhibit an early volume increase with diffusion restriction after LITT. Responders then show bi-exponential shrinkage with gradual diffusion increase. Progression can usually be detected only after 3-4 months, because earlier radiographic patterns may overlap with responding lesions.</p><p><strong>Key points: </strong>Question Laser interstitial thermal therapy (LITT) is an emerging local treatment for brain metastases, but the radiographic patterns following this treatment have not been thoroughly described. Findings Responding lesions showed a typical radiographic pattern with early volumetric enlargement and diffusion restriction (not exclusive of responders), followed by a bi-exponential shrinkage and diffusion elevation. Clinical relevance Being aware of the typical radiographic changes in brain metastases responding to LITT is informative for the interpretation of follow-up images. Early volumetric and diffusion changes (< 3-4 months) do not appear to be reliable markers to predict treatment success.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":"5981-5993"},"PeriodicalIF":4.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fibroblast activation imaging in rheumatoid arthritis: evaluating disease activity and treatment response using [¹⁸F]FAPI PET/CT.","authors":"Xingyu Mu, Fangyue Zhang, Meng Li, Lu Lu, Biyun Mo, Baozhen Li, Min Yang, Wei Fu","doi":"10.1007/s00330-025-11610-4","DOIUrl":"10.1007/s00330-025-11610-4","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the utility of fibroblast activation protein (FAP) imaging using [¹⁸F]FAPI PET/CT for assessing disease activity and monitoring treatment response in rheumatoid arthritis (RA).</p><p><strong>Materials and methods: </strong>A prospective, single-center study was conducted with 42 RA patients and 8 healthy controls. Participants underwent clinical assessment and [¹⁸F]FAPI PET/CT imaging. Semiquantitative parameters, including standardized uptake value maximum (SUV_max), lesion-to-muscle ratio (LMR), [¹⁸F]FAPI-avid lesion volume (FLV), and total lesion FAP expression (TLF), were analyzed. Disease activity was stratified by the disease activity score-28 using C-reactive protein (DAS28-CRP) into three groups (low, moderate, and high). Correlations between PET/CT parameters and disease acitivity were examined, and follow-up imaging was performed in ten patients to assess treatment response.</p><p><strong>Results: </strong>[¹⁸F]FAPI PET/CT identified 201 RA-affected joints with significantly higher SUV_max in positive joints compared to controls (median 3.6 vs 2.4; p < 0.01). High disease activity was associated with increased SUV_max (median 5.6 vs 3.3 vs 2.8; p < 0.05), TBR (median 8.4 vs 3.0 vs 3.6; p < 0.05), FLV (162.2 vs 11.5 vs 9.8; p < 0.01), and TLF (569.1 vs 27.3 vs 22.7; p < 0.01). Positive correlations were observed between DAS28-CRP and both FLV (r = 0.50, p < 0.01) and TLF (r = 0.51, p < 0.01). Follow-up imaging revealed significant associations between changes in disease activity and FAP burden.</p><p><strong>Conclusion: </strong>[¹⁸F]FAPI PET/CT is a promising tool for non-invasive assessment of RA disease activity. It provides quantitative insights into fibroblast activation, offering potential to enhance disease management and therapeutic planning.</p><p><strong>Key points: </strong>Question What is the potential of fibroblast activation imaging using [¹⁸F]FAPI PET/CT for assessing RA disease activity and monitoring treatment response? Findings ¹⁸F]FAPI PET/CT effectively identifies joint involvement and quantifies fibroblast activation, correlating closely with clinical disease activity in RA. Clinical relevance [¹⁸F]FAPI PET/CT provides a non-invasive, comprehensive assessment of RA activity, and possible cutoff values for identifying high disease activity.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":"6104-6114"},"PeriodicalIF":4.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143998266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pituitary MRI features in identifying idiopathic short stature from growth hormone deficiency in children with short stature.","authors":"Longbiao Cai, Xiongjing Cao, Jianjian Cai, Qin Liu, Yunyun Zhao, Xianrong Kong, Guojun Ding, Tian Tian, Weiyin Vivian Liu, Dong Liu","doi":"10.1007/s00330-025-11556-7","DOIUrl":"10.1007/s00330-025-11556-7","url":null,"abstract":"<p><strong>Objective: </strong>This study examined the diagnostic performance of the prediction models using baseline characteristics, biochemical indicators, and adenohypophysis MRI features for differentiating idiopathic short stature (ISS) from growth hormone deficiency (GHD).</p><p><strong>Methods: </strong>A total of 96 patients with short stature underwent hypophysial CUBE T1-weighted imaging on 3.0-T scanner and GH stimulation testing between February 2021 and February 2024 and were classified into ISS and GHD groups according to GH stimulation testing results. Two-independent-sample T-test was tested for the differences between groups. The partial correlation analysis was conducted after controlling for demographic data. The prediction models were established using stepwise binary logistic regression method. Receiver operating characteristic (ROC) curve analysis was performed to evaluate the diagnostic efficacy of the models.</p><p><strong>Results: </strong>ISS group (29 boys and 29 girls) and GHD group (21 boys and 17 girls) showed significant differences in pituitary height (aPH) and pituitary volume (aPV), GH_max, LH_max and cortisol but no difference in demographic data (gender, age, height, weight and BMI). After controlling for those demographic data, aPH, aPV, FSH_max and LH_max showed positive correlation with GH_max. Using binary logistic regression, three prediction models were built; Model 1 had the highest AUC value (0.862) followed by Model 3 with AUC value of 0.858 and Model 2 with the lowest AUC value (0.725).</p><p><strong>Conclusion: </strong>A useful prediction model using adenohypophysis MRI features, age, and BMI had great potential in differentiation between GHD and ISS.</p><p><strong>Key points: </strong>Question Distinguishing growth hormone deficiency (GHD) from idiopathic short stature (ISS) among prepubescent children is important but difficult, time-consuming, and costly with growth hormone stimulation testing. Findings The proposed model using clinical and radiomics features offered sufficient diagnostic performance on differentiating GHD and ISS. Clinical relevance We propose a low-cost, time-saving, and non-invasive model based on adenohypophysis MRI features and baseline characteristics to differentiate GHD and ISS.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":"6183-6192"},"PeriodicalIF":4.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143998404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-time dosimetry in interventional radiology - comparing the occupational radiation exposure in fluoroscopy-guided lower extremity and abdominal procedures.","authors":"Kristina Krompaß, Mareike Mutschler, Jan-Peter Grunz, Annette Thurner, Thorsten Alexander Bley, Wolfram Voelker, Ralph Kickuth","doi":"10.1007/s00330-025-11566-5","DOIUrl":"10.1007/s00330-025-11566-5","url":null,"abstract":"<p><strong>Objective: </strong>Radiation safety concerns have spurred the development of real-time dosimetry systems. This study investigated the occupational dose exposure of interventional radiologists during lower extremity and abdominal procedures.</p><p><strong>Materials and methods: </strong>Real-time dosimetry was performed during 102 consecutive interventions (51 lower extremity, 51 abdominal). Radiation protection measures included protective glasses (lead equivalent 0.5 mm), thyroid shielding (0.5 mm), vests (0.35 mm), aprons (0.25 mm), as well as movable acrylic and table shields (both 0.5 mm) during all procedures. Dosimeters were attached to the interventionalist's glasses on the side of the x-ray tube, to the back of the supporting hand, and under the vest. Using standardized values over time to account for exposure time differences between interventions, dose-area products and the dose equivalent H_P(10) were recorded in all three positions.</p><p><strong>Results: </strong>Lower extremity angiographies were associated with a substantially lower median dose-area product (5.3 vs. 51.4 Gy × cm²) and exposure time (462 vs. 762 s) than abdominal interventions (both p < 0.001). For lower extremity procedures, H_P(10) per minute recorded by the hand, cranium/eye lens, and body trunk dosimeters was 2.45, 0.01, and < 0.01 µSv/min, respectively. Markedly higher dose equivalents were documented for the hand (7.54 µSv/min), cranium/eye lens (0.26 µSv/min), and body trunk (0.04 µSv/min) during abdominal interventions (all p < 0.001).</p><p><strong>Conclusion: </strong>Real-time dosimetry confirmed sufficient radiation protection with the application of dedicated safety measures, even in dose-intensive abdominal procedures. Interventionalists' supporting hands are subjected to the highest radiation exposure, followed by the cranium/eye lens and the body trunk.</p><p><strong>Key points: </strong>Question Active dosimetry facilitates real-time assessment of radiation exposure in different measurement sites, but a multi-dosimeter setup has not been explored for interventional radiology so far. Findings Occupational radiation exposure is considerably higher in abdominal than in lower extremity procedures. Interventionalists' supporting hands receive the highest dose equivalents regardless of procedure type. Clinical relevance Dose monitoring in real time is key to understanding the radiation burden of different anatomical features during image-guided interventions. Especially in dose-intensive abdominal procedures, protective measures are essential to minimize the occupational radiation exposure of the interventionalist.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":"6575-6582"},"PeriodicalIF":4.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of visual objects and music on anxiety levels and imaging process in patients undergoing coronary CT angiography.","authors":"Muhammed Tekinhatun, Kadir Han Alver, İbrahim Akbudak, Mehmet Turmak, Eyyup Çavdar, Muhammed Akif Deniz","doi":"10.1007/s00330-025-11614-0","DOIUrl":"10.1007/s00330-025-11614-0","url":null,"abstract":"<p><strong>Objective: </strong>High anxiety during coronary computed tomography angiography (CCTA) can compromise imaging quality, increase radiation exposure, and elevate medication use. Therefore, optimizing waiting room environments to reduce patient anxiety is important for clinical outcomes. This study examines the effects of music and visual stimuli in the waiting rooms on patients' anxiety levels, heart rate, radiation dose, and beta-blocker use prior to CCTA.</p><p><strong>Methods: </strong>This study, designed as a prospective and randomized trial, was conducted between April 15 and August 15, 2024, with 216 patients randomized into two groups: a standard waiting room (SWR) and a designed waiting room (DWR) featuring music and visual objects. Anxiety and depression levels were measured using the Hospital Anxiety and Depression Scale (HADS) and the State-Trait Anxiety Inventory (STAI). Additional parameters, such as heart rate, radiation dose, and beta-blocker requirement, were also recorded.</p><p><strong>Results: </strong>In the DWR group, anxiety scores and heart rates were significantly lower compared to the SWR group (p < 0.001). Additionally, a notable reduction in radiation dose and beta-blocker use was observed in the DWR group (p < 0.05). In the general patient population, higher anxiety scores were associated with poorer imaging quality. Imaging quality was significantly better in the DWR group (p < 0.001).</p><p><strong>Conclusion: </strong>It has been demonstrated that waiting room designs enriched with music and visual stimuli reduce anxiety during CCTA scanning, enhancing patient comfort, improving imaging quality, and enabling imaging with lower radiation doses. The design of such waiting rooms can improve patient experience while optimizing outcomes.</p><p><strong>Key points: </strong>Question Can a waiting room with music and visual stimuli reduce anxiety and heart rate in CCTA patients, improving imaging quality and reducing beta-blocker use? Findings Music and visual stimuli reduced anxiety and heart rate, lowering beta-blocker use and radiation doses while improving imaging quality in CCTA. Clinical relevance Integrating music and visual stimuli in waiting rooms helps reduce anxiety and heart rate, leading to less medication use and radiation exposure while enhancing imaging quality. This simple, cost-effective approach improves patient comfort and optimizes outcomes in CCTA procedures.</p>","PeriodicalId":12076,"journal":{"name":"European Radiology","volume":" ","pages":"6323-6335"},"PeriodicalIF":4.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}