Zachary J McKenna, Bryanne N Bellovary, Jeremy B Ducharme, Michael R Deyhle, Andrew D Wells, Zachary J Fennel, Jonathan W Specht, Jonathan M Houck, Trevor J Mayschak, Christine M Mermier
{"title":"Circulating markers of intestinal barrier injury and inflammation following exertion in hypobaric hypoxia.","authors":"Zachary J McKenna, Bryanne N Bellovary, Jeremy B Ducharme, Michael R Deyhle, Andrew D Wells, Zachary J Fennel, Jonathan W Specht, Jonathan M Houck, Trevor J Mayschak, Christine M Mermier","doi":"10.1080/17461391.2023.2203107","DOIUrl":"10.1080/17461391.2023.2203107","url":null,"abstract":"<p><p>Hypoxia induced intestinal barrier injury, microbial translocation, and local/systemic inflammation may contribute to high-altitude associated gastrointestinal complications or symptoms of acute mountain sickness (AMS). Therefore, we tested the hypothesis that six-hours of hypobaric hypoxia increases circulating markers of intestinal barrier injury and inflammation. A secondary aim was to determine if the changes in these markers were different between those with and without AMS. Thirteen participants were exposed to six hours of hypobaric hypoxia, simulating an altitude of 4572 m. Participants completed two 30-minute bouts of exercise during the early hours of hypoxic exposure to mimic typical activity required by those at high altitude. Pre- and post-exposure blood samples were assessed for circulating markers of intestinal barrier injury and inflammation. Data below are presented as mean ± standard deviation or median [interquartile range]. Intestinal fatty acid binding protein (Δ251 [103-410] pg•mL<sup>-1</sup>; <i>p</i> = 0.002, d = 0.32), lipopolysaccharide binding protein (Δ2 ± 2.4 μg•mL<sup>-1</sup>; <i>p</i> = 0.011; d = 0.48), tumor necrosis factor-α (Δ10.2 [3-42.2] pg•mL<sup>-1</sup>; <i>p</i> = 0.005; d = 0.25), interleukin-1β (Δ1.5 [0-6.7] pg•mL<sup>-1</sup> <i>p</i> = 0.042; d = 0.18), and interleukin-1 receptor agonist (Δ3.4 [0.4-5.2] pg•mL<sup>-1</sup><i>p</i> = 0.002; d = 0.23) increased from pre- to post-hypoxia. Six of the 13 participants developed AMS; however, the pre- to post-hypoxia changes for each marker were not different between those with and without AMS (<i>p</i> > 0.05 for all indices). These data provide evidence that high altitude exposures can lead to intestinal barrier injury, which may be an important consideration for mountaineers, military personnel, wildland firefighters, and athletes who travel to high altitudes to perform physical work or exercise.</p>","PeriodicalId":12061,"journal":{"name":"European Journal of Sport Science","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9368145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Senanile B Dlamini, Colleen J Saunders, Mary-Jessica N Laguette, Andrea Gibbon, Junaid Gamieldien, Malcolm Collins, Alison V September
{"title":"Application of an <i>in silico</i> approach identifies a genetic locus within <i>ITGB2,</i> and its interactions with <i>HSPG2 and FGF9,</i> to be associated with anterior cruciate ligament rupture risk.","authors":"Senanile B Dlamini, Colleen J Saunders, Mary-Jessica N Laguette, Andrea Gibbon, Junaid Gamieldien, Malcolm Collins, Alison V September","doi":"10.1080/17461391.2023.2171906","DOIUrl":"10.1080/17461391.2023.2171906","url":null,"abstract":"ABSTRACT We developed a Biomedical Knowledge Graph model that is phenotype and biological function-aware through integrating knowledge from multiple domains in a Neo4j, graph database. All known human genes were assessed through the model to identify potential new risk genes for anterior cruciate ligament (ACL) ruptures and Achilles tendinopathy (AT). Genes were prioritised and explored in a case–control study comparing participants with ACL ruptures (ACL-R), including a sub-group with non-contact mechanism injuries (ACL-NON), to uninjured control individuals (CON). After gene filtering, 3376 genes, including 411 genes identified through previous whole exome sequencing, were found to be potentially linked to AT and ACL ruptures. Four variants were prioritised: HSPG2:rs2291826A/G, HSPG2:rs2291827G/A, ITGB2:rs2230528C/T and FGF9:rs2274296C/T. The rs2230528 CC genotype was over-represented in the CON group compared to ACL-R (p < 0.001) and ACL-NON (p < 0.001) and the TT genotype and T allele were over-represented in the ACL-R group and ACL-NON compared to CON (p < 0.001) group. Several significant differences in distributions were noted for the gene-gene interactions: (HSPG2:rs2291826, rs2291827 and ITGB2:rs2230528) and (ITGB2:rs2230528 and FGF9:rs2297429). This study substantiates the efficiency of using a prior knowledge-driven in silico approach to identify candidate genes linked to tendon and ACL injuries. Our biomedical knowledge graph identified and, with further testing, highlighted novel associations of the ITGB2 gene which has not been explored in a genetic case control association study, with ACL rupture risk. We thus recommend a multistep approach including bioinformatics in conjunction with next generation sequencing technology to improve the discovery potential of genomics technologies in musculoskeletal soft tissue injuries. Highlights A biomedical knowledge graph was modelled for musculoskeletal soft tissue injuries to efficiently identify candidate genes for genetic susceptibility analyses. The biomedical knowledge graph and sequencing data identified potential biologically relevant variants to explore susceptibility to common tendon and ligament injuries. Specifically genetic variants within the ITGB2 and FGF9 genes were associated with ACL risk. Novel allele combinations (HSPG2-ITGB2 and ITGB2-FGF9) showcase the potential effect of ITGB2 in influencing risk of ACL rupture.","PeriodicalId":12061,"journal":{"name":"European Journal of Sport Science","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10757675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"L-menthol administration facilitates breathing comfort during exhaustive endurance running and improves running capacity in well-trained runners: A randomized crossover study.","authors":"Yoshiko Tsutsumi, Haruki Momma, Satoru Ebihara, Ryoichi Nagatomi","doi":"10.1080/17461391.2022.2115404","DOIUrl":"10.1080/17461391.2022.2115404","url":null,"abstract":"<p><p><b>ABSTRACT</b>This study aimed to clarify the contribution of L-menthol administration to endurande exercise capacity. Thirteen male runners (age, 35.8 ± 7.8 years; peak oxygen uptake, 62.7 ± 6.8 mL kg<sup>-1</sup> min<sup>-1</sup>) ran on treadmills at fixed intensities of their anaerobic thresholds to exhaustion. All participants underwent three trials-water ingestion (W-IG), L-menthol mouth rinsing (M-MR), and L-menthol ingestion (M-IG)- in a random order every 5 min while running. Breathing comfort (BC) was measured immediately after fluid intake. Dyspnea threshold against external inspiratory resistance was examined before and after the running test. The running time with M-IG (1683.9 ± 520.3 s) was longer than that with W-IG (1410.2 ± 465.9 s, effect size [ES] = 0.55). BC with M-IG (2.00 ± 0.74) was higher than that with W-IG (0.42 ± 0.79) at exhaustion (ES > 2.00). The dyspnea threshold after running decreased to 19.2 ± 7.6 cm H<sub>₂</sub>O L<sup>-1</sup> s<sup>-1</sup> with W-IG, whereas that with M-MR (26.2 ± 6.5 cm H<sub>₂</sub>O L<sup>-1</sup> s<sup>-1</sup>) and M-IG (29.2 ± 2.8 cm H<sub>₂</sub>O L<sup>-1</sup> s<sup>-1</sup>) remained high (p for interaction < 0.001). M-IG facilitated BC during running, improved endurance capacity, and prevented decreases in the dyspnea threshold against external inspiratory resistance after exhaustive running.<b>Highlights</b>L-menthol ingestion facilitated breathing comfort during high intensity endurance running and improved exhaustive endurance running capacity.Even after exhaustion, L-menthol solution relieved dyspnea sensitivity against external inspiratory resistance.L-menthol ingestion might help athletes improve their endurance running capacity.</p>","PeriodicalId":12061,"journal":{"name":"European Journal of Sport Science","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40633200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlos Galiano, Pablo Floria, Alejandro Muñoz-López, Eduardo Sáez de Villarreal, Francisco Javier Nuñez
{"title":"Stable vs. variable eccentric load. Do they induce different training and physical performance outcomes?","authors":"Carlos Galiano, Pablo Floria, Alejandro Muñoz-López, Eduardo Sáez de Villarreal, Francisco Javier Nuñez","doi":"10.1080/17461391.2022.2118081","DOIUrl":"10.1080/17461391.2022.2118081","url":null,"abstract":"<p><p>Since most movements on the field require athletes to produce forces in variable and unpredictable contexts, the use of training programs based on identical repetitions of an exercise may not be optimal for movement transference. Therefore, the aim of this study was to analyse the effects of unexpected eccentric load variability during resistance training in team sport players. Sixty-three men were randomly allocated to two experimental groups (Variable (VTG) and stable (STG) training group) and control group: (CG) volunteered to participate in this study. Experimental groups trained with the same average load of half-squat exercise twice a week for six weeks using rotary inertial devices (RIDs) with (VTG) and without (STG) an unexpected variability of the load. The squat force was measured for every session with force plates. Counter-movement jump (CMJ), sprint, and change of direction performances were measured pre and post-test. CMJ performance improved for VTG (<i>p </i>= .014; ES = 0.7) and STG (<i>p</i> = .005; ES = 0.79) but not for CG. Exposure to high eccentric forces with RIDs lead athletes to improve physical performance in the trained force vector but, since RIDs induce in high levels of variability per se, increasing the level of variability of the exercise will not add benefits to physical performance and training outcomes.<b>HIGHLIGHTS</b>The relevance of the study is to analyse if increasing the variability of the load will improve the athlete output to different physical performance tests.The exposure to eccentric overload with RIDs during the squat exercise allows to greater CMJ height improvements than those seen in the literature with RIDs without overloading the eccentric contraction.RIDs induce in high level of variability <i>per se</i>. Therefore, increasing the level of variability of the exercise will not add benefits to physical performance and training outcomes.</p>","PeriodicalId":12061,"journal":{"name":"European Journal of Sport Science","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33438565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C Sánchez-Muñoz, M Mateo-March, J J Muros, A Javaloyes, M Zabala
{"title":"Anthropometric characteristics according to the role performed by World Tour road cyclists for their team.","authors":"C Sánchez-Muñoz, M Mateo-March, J J Muros, A Javaloyes, M Zabala","doi":"10.1080/17461391.2022.2132879","DOIUrl":"10.1080/17461391.2022.2132879","url":null,"abstract":"<p><p>Certain anthropometric characteristics are required for athletes to successfully perform in elite endurance sports. The present study aims to analyse the anthropometric characteristics of professional cyclists according to their specialty. Anthropometric measurements were conducted of the body composition of 76 male professional road cyclists in line with International Society for Advancement of Kinanthropometry protocol. Fat mass did not differ (p > 0.05) between climbers, all-rounders and flat specialists, although the following anthropometric variables did differ according to the role played within the team (p < 0.05): Body mass (climbers: 63.8 ± 3.6, all-rounders: 68.8 ± 5.3, flat specialists: 74.5 ± 5.6 kg) skeletal body mass (climbers: 29.7 ± 1.6, all-rounders: 31.4 ± 1.9, flat specialists: 33.5 ± 2.4 kg); body surface area (climbers: 1.78 ± 0.07, all-rounders: 1.89 ± 0.10, flat specialists: 1.96 ± 0.1 m2); frontal area (climbers: 0.33 ± 0.01, all-rounders: 0.35 ± 0.02, flat specialists: 0.36 ± 0.02 m2). Anthropometric characteristics differ between world-class cyclists depending on their specialty. These differences could influence performance in relation to different types of road cycling competitions. The present study identified characteristics that could be used by coaches to evaluate their athletes in the context of elite or professional road cycling.<b>Highlights</b>Normative reference values of a large sample of professional cyclists of the highest category are presented.Anthropometric characteristics differ between world-class cyclists depending on their specialty.Body mass, BMI, height and skeletal muscle mass are determining factors to determine the role of the cyclist.</p>","PeriodicalId":12061,"journal":{"name":"European Journal of Sport Science","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33491698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Benjamin W C Jerome, Michael Stoeckl, Ben Mackriell, Thomas Seidl, Christian W Dawson, Daniel T P Fong, Jonathan P Folland
{"title":"The influence of ball in/out of play and possession in elite soccer: Towards a more valid measure of physical intensity during competitive match-play.","authors":"Benjamin W C Jerome, Michael Stoeckl, Ben Mackriell, Thomas Seidl, Christian W Dawson, Daniel T P Fong, Jonathan P Folland","doi":"10.1080/17461391.2023.2203120","DOIUrl":"10.1080/17461391.2023.2203120","url":null,"abstract":"<p><p>The physical demands of soccer match-play have typically been assessed using a low-resolution whole match approach ignoring whether the ball is in or out of play (BIP/BOP) and during these periods which team has possession. This study investigated the effect of fundamental match structure variables (BIP/BOP, in/out of possession) on the physical demands, and especially intensity, of elite match-play. For 1083 matches from a major European league, whole match duration, and player physical tracking data, were divided into BIP/BOP, and in/out of possession periods throughout the match, using on-ball event data. These distinct phases were used to derive absolute (m) and rate (m·min<sup>-1</sup>) of distance covered in total and within six speed categories during BIP/BOP and in/out possession. The rate of distance covered, an index of physical intensity, was >2-fold greater during BIP vs BOP. Whole match total distance covered was confounded by BIP time and poorly associated with physical intensity during BIP (<i>r </i>= 0.36). Whole match rates of distance covered substantially underestimated those during BIP, particularly for higher running speeds (∼-62%). Ball possession markedly effected physical intensity, with the rates of distance covered running (+31%), at high-speed (+30%) and in total (+7%) greater out than in possession. Whole match physical metrics underestimated the physical intensity during BIP, and thus the rate(s) of distance covered during BIP are recommended for accurate measurement of physical intensity in elite soccer. The greater demands of being out of possession support a possession-based tactical approach to minimise fatigue and its negative consequences.</p>","PeriodicalId":12061,"journal":{"name":"European Journal of Sport Science","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9573068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alba Cuba-Dorado, Tania Álvarez-Yates, Javier Carballo-López, Mario Iglesias-Caamaño, Diego Fernández-Redondo, Oscar García-García
{"title":"Neuromuscular changes after a Long Distance Triathlon World Championship.","authors":"Alba Cuba-Dorado, Tania Álvarez-Yates, Javier Carballo-López, Mario Iglesias-Caamaño, Diego Fernández-Redondo, Oscar García-García","doi":"10.1080/17461391.2022.2134053","DOIUrl":"10.1080/17461391.2022.2134053","url":null,"abstract":"<p><p><b>ABSTRACT</b>This study aimed to determine the neuromuscular changes in muscle contractile properties and countermovement jump (CMJ) performance after a long distance (LD) triathlon, inquiring to what extent it is influenced by gender and the evaluated muscle, and to explore for response differences. Four elite (2 females and 2 males) and 18 well-trained triathletes (3 females and 15 males) who competed in the 2019 LD Triathlon World Championship undergone, prior and post-race, a CMJ and a muscle contractile properties assessment in vastus lateralis (VL) and biceps femoris (BF) using tensiomyography. A mixed ANOVA was carried out to detect triathletes' neuromuscular changes after the competition. A large decrease in jump height and flight time was found in CMJ (<i>p</i> = 0.001, η<sub>p</sub><sup>2 </sup>= 0.767) with gender differences (η<sub>p</sub><sup>2</sup><sub> </sub>= 0.308). contraction (Tc), delay (Td) and sustain times (Ts) also showed a large decrease (<i>p</i> = 0.001, η<sub>p</sub><sup>2</sup><sub> </sub>= 0.174-0.413). However, maximum radial muscle belly displacement was not altered by the competition, but did greatly increase radial displacement velocity (<i>p</i> = 0.031; η<sub>p</sub><sup>2</sup><sub> </sub>= 0.212). No gender differences were found in contractile properties. Correlation analysis between race performance and the jumping and tensiomyography parameters only showed a moderate negative correlation with Tc of the BF in pre- and post-competition (<i>r</i> = -0.44; -0.43; <i>p</i> = 0.05). In conclusion, triathletes after a LD World Championship suffer a sharp drop in jump performance and variations in VL's and BF's contractile properties, showing decreases in Tc, Td and Ts without gender differences. The regular use of these parameters can allow the monitoring of triathlete's neuromuscular fatigue and aid in the distribution of more efficient loads in their training cycles.<b>Highlights</b>Trainers and researchers in neuromuscular fatigue can have reference data of elite and well-trained triathletes after performing LD race.The magnitude of change in the CMJ and the contractile properties of BF and VL achieved in competition by these elite reference triathletes can guide to modulate triathletes training.The regular use of the parameters using these references can allow an exhaustive neuromuscular fatigue monitoring during the sessions or training cycles throughout the season.</p>","PeriodicalId":12061,"journal":{"name":"European Journal of Sport Science","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33501188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luke Nicholas Woodhouse, Mark Bennett, Jamie Tallent, Stephen David Patterson, Mark Waldron
{"title":"The relationship between physical characteristics and match collision performance among elite international female rugby union players.","authors":"Luke Nicholas Woodhouse, Mark Bennett, Jamie Tallent, Stephen David Patterson, Mark Waldron","doi":"10.1080/17461391.2022.2144765","DOIUrl":"10.1080/17461391.2022.2144765","url":null,"abstract":"<p><p>This study investigated whether anthropometric and physical abilities explained variance in match collision performance among international female rugby union players. Physical performance and anthropometric data for fifty-one international female rugby union players, and collision actions categorised as \"effort\" or \"performance\" variables, from 20 international matches, were analysed using partial least squares regression. Among forwards, variance in carries/min was explained (R<sup>2 </sup>= .22) by a combination of; body mass, skinfolds, acceleration momentum and negative associations with mean aerobic speed and single-leg isometric squat relative force (SLISO/kgBM). Variance in collision dominance among forwards was explained (R<sup>2</sup> = .21) by lower skinfolds and higher acceleration momentum, while tackles/min (R<sup>2</sup> = .19) were explained by greater jumping power and single-leg isometric squat (SLISO). Among backs, variance in tackles/min (R<sup>2</sup> = .54) was explained by greater bench press, SLISO and SLISO/kgBM. Variance in collision dominance among backs was explained (R<sup>2</sup> = .23) by negative and positive associations with body mass and SLISO/kgBM, respectively. These findings suggest the development of physical characteristics, such as body mass and composition, strength and power contribute towards successful collision actions among international female rugby union players. The contribution of different physical characteristics towards collision events is dependent on position, and whether the collision event is categorised by \"performance\" or \"effort\". It is suggested that physical training programmes should reflect this level of specificity.<b>Highlights</b>Among elite female rugby union forwards, acceleration momentum, body mass and skinfolds are positively associated with winning collisions and carrying the ball into contact more frequently, whilst tackle frequency is positively associated with relative leg strength and power output.Among elite female backs, the ability to win collisions is positively associated with relative leg power output, and negatively associated with body mass. Tackle frequency is associated with maximum upper- and lower-body strength in this group.Physical characteristics account for some of the variability in collision performance, but interpretation of these findings should consider that factors such as technique during collision events may account for a larger proportion of total variance.Sports science practitioners can improve collision performance, to varying degrees, by enhancing specific gross physical characteristics, according to a player's position and the tactical role they are expected to fulfil.</p>","PeriodicalId":12061,"journal":{"name":"European Journal of Sport Science","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10380640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sabrina Skorski, Werner Pitsch, Vanessa Barth, Max Walter, Mark Pfeiffer, Alexander Ferrauti, Michael Kellmann, Anne Hecksteden, Tim Meyer
{"title":"Individualised reference ranges for markers of muscle recovery assessment in soccer.","authors":"Sabrina Skorski, Werner Pitsch, Vanessa Barth, Max Walter, Mark Pfeiffer, Alexander Ferrauti, Michael Kellmann, Anne Hecksteden, Tim Meyer","doi":"10.1080/17461391.2022.2134052","DOIUrl":"10.1080/17461391.2022.2134052","url":null,"abstract":"<p><p>Recently an individualisation algorithm has been developed and shown to significantly improve the diagnostic accuracy of creatine kinase (CK) and urea in endurance sports and Badminton. In this study, the applicability and benefit of this algorithm was evaluated using repeated measures data from 161 professional German soccer players monitored during the 2015-2017 seasons. Venous blood samples were collected after a day off (recovered state) and after a minimum of two strenuous training sessions within 48 h (non-recovered state) and analysed for CK and urea. Group-based reference ranges were derived from that same dataset to ensure the best possible reference for comparison. A <i>z</i>-test was conducted to analyse differences in error rates between individualised and group-based classifications. CK values for the individualised approach showed significantly lower error rates in the assessment of muscle recovery compared to both a population-based (<i>p</i> < .001; <i>z</i>-value: -17.01; test-pass error rate: 21 vs. 67%; test-fail: 19 vs. 64%) and a group-based cut-off (<i>p</i> < .001; <i>z</i>-value: -15.29; test-pass error rate: 65%; test-fail: 67%). It could be concluded that the assessment of muscle recovery in soccer using individualised interpretations of blood-borne markers may offer higher diagnostic accuracy than a population-based and a sample-specific group-based approach.<b>Highlights</b>Assessing muscle recovery via CK using individualised ranges seems to offer a higher diagnostic accuracy than a sample-specific group-based analysis.Using an individualised algorithm seems to be a promising approach to overcome diagnostic problems arising from large inter- and intraindividual variability in blood parameters as it significantly improved the diagnostic accuracy of CK as a recovery marker.As recovery assessment in elite soccer ultimately aims at the accurate detection of differences in the individual player this algorithm seems to offer coaches and sport scientists a more sensitive approach compared to group-specific evaluations.</p>","PeriodicalId":12061,"journal":{"name":"European Journal of Sport Science","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33528257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Justine R Magnuson, Hogun J Kang, Mathew I B Debenham, Chris J McNeil, Brian H Dalton
{"title":"Effects of sleep deprivation on perceived and performance fatigability in females: An exploratory study.","authors":"Justine R Magnuson, Hogun J Kang, Mathew I B Debenham, Chris J McNeil, Brian H Dalton","doi":"10.1080/17461391.2022.2115944","DOIUrl":"10.1080/17461391.2022.2115944","url":null,"abstract":"<p><p>Sleep deprivation (SD) is prevalent and impairs motor function; however, little is known about its effect on perceived and performance fatigability, especially in females. To examine the effects of 24 h of SD on these attributes of fatigue, nine females completed a 20-min isometric, sustained elbow flexion contraction, followed by 10 min of recovery. The superimposed twitch (SIT) elicited via transcranial magnetic stimulation (TMS) assessed supraspinal drive. Biceps brachii electromyographic data indicated neural excitability in response to stimulation over the motor cortex (motor evoked potential; MEP), corticospinal tract (cervicomedullary motor evoked potential; CMEP), and brachial plexus (maximal M-wave; Mmax). MEPs and CMEPs were recorded during a TMS-induced silent period. At baseline, ratings of perceived effort (RPE; 2.9 vs. 1.6) and fatigue (RPF; 6.9 vs. 2.9), were higher for SD than control. Across the 20-min contraction, RPE increased from 2.2 to 7.6, SIT and MEP/CMEP increased by 284 and 474%, respectively, whereas maximal voluntary isometric contraction (MVC) torque and CMEP/Mmax decreased by 26 and 57%, respectively. No differences were found across conditions for MVC, SIT, Mmax, CMEP/Mmax, or MEP/CMEP prior to, during, and after the fatiguing task. During recovery, RPE (4.9 vs. 3.4), RPF (7.6 vs. 2.8), and perception of task difficulty (5.5 vs. 4.5) were greater for SD than control. Acute SD does not appear to alter performance fatigability development and subsequent recovery; however, it increases perceptions of fatigue, effort, and task difficulty. Thus, the disconnect between perceived and actual neuromuscular capacity following a sustained, submaximal isometric task is exacerbated by SD.<b>Highlights</b>Sleep deprivation did not alter supraspinal drive or neural excitability during and after a 20-min submaximal elbow flexion contractionSleep deprivation increased perceived fatigue and perception of task difficultyThe disconnect between perceived and performance fatigability is exacerbated in a sleep-deprived state.</p>","PeriodicalId":12061,"journal":{"name":"European Journal of Sport Science","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40643355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}