{"title":"Cultivation of Vetiver (Chrysopogon zizanioides (L.) Roberty)- A Versatile Medicinal and Aromatic Plant","authors":"Yashaswini Sharma","doi":"10.9734/ejmp/2024/v35i51199","DOIUrl":"https://doi.org/10.9734/ejmp/2024/v35i51199","url":null,"abstract":"Vetiver (Chrysopogon zizanioides) is a versatile medicinal and aromatic plant mainly used for soil and conservation purposes. It is a perennial grass species with a densely tufted enormous root system that grows up to two meters long. The fibrous roots are highly aromatic and used for extraction of essential oils used in high-grade perfumes as a base or fixative for their long-lasting characteristic odor. The fragrant dry roots are traditionally used for water purification in south India. Besides, the consumption of vetiver-treated water has cooling properties and refreshes the body and mind. It also acts as a deodorant and stimulant, aids digestion, and has carminative, colic, anthelmintic, and antioxidant properties. It is a very hard grass, suitable for growing in wastelands, arid regions, and hill slopes with the least maintenance. The worldwide demand for vetiver oil was estimated at around 408.8 t/year in 2019, and the growth was reported to increase at a CAGR of 7.8 % from 2020-2027. India consumes 100 tons of vetiver oil annually; the domestic production is only 20 tons, and the remaining 80 % of the oil is imported. Hence, there is a lot of scope for increasing the vetiver area in India and globally. Looking at its vast utilization and demand, an attempt has been made to present the improved cultivation practices of vetiver based on the literature survey and experience. ","PeriodicalId":11969,"journal":{"name":"European journal of medicinal plants","volume":"29 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141805022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influence of Certain Biostimulants on the Vegetative Growth of Annual Moringa (Moringa oleifera. Lam)","authors":"Huria, F. M, E. H. Shaaban, M. K. Gaber","doi":"10.9734/ejmp/2024/v35i51198","DOIUrl":"https://doi.org/10.9734/ejmp/2024/v35i51198","url":null,"abstract":"Due to the importance of moringa leaves which can help improve the dietary diversity and quality of households that need to improve their nutritional intake, being a potential alternate source of protein, and for the sake of increasing its growth and yield, this study is determine the effect of some biofertilizers, amino acids and seaweed extract on vegetative growth of moringa seedlings As well as, to find out the best fertilization treatment to improve the vegetative growth of Moringa and reducing the intensive use of chemical fertilizers. This study was conducted in the Experimental Farm of the Faculty of Agriculture (Saba-Basha), Alexandria University, Egypt, during two consecutive seasons of 2020 and 2021, to study the effect of biofertilizers, amino acids, and seaweed extract and its combinations on the growth of Moringa (Moringa oleifera, L.). The experiment was designed as split-split plot design it included 27 treatments with three replicates. The results revealed that the highest significant values of vegetative growth as plant height (171.8 cm), stem length (87.30 cm), stem diameter (3.49 cm), leaves fresh weight (70.61 g), leaves dry weight (13.35g), number of leaves per plant (72.03), and number of leaves per shoot (54.41) were achieved when the trees were soil bio-fertilized and sprayed with the investigated amino acid 700 mg/l + seaweed extract 700 mg/l + cerealine (T26) for both seasons of study. While the number of branches per plant (15.28), shoot fresh weight (138.1g), and shoot dry weight (24.07g) were concerned, the highest values were obtained when the plants were treated with soil bio-fertilization (Phosphorine), sprayed with amino acids, and seaweed extract, as the abovementioned treatments, amino acid 700 mg/l + seaweed extract 700 mg/l + Phosphorine (T25), for both seasons of study compared to the other treatments and control.","PeriodicalId":11969,"journal":{"name":"European journal of medicinal plants","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141813704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thaynara Monteiro Paiva Garcia, Mateus Silva Tavares, Renan Miranda Correa, Anthony Matheus dos Santos Gomes, Luana Nóbrega dos Santos, Anderson Lima Bentes, Rita de Cássia Silva de Oliveira
{"title":"Potential Biological and Antimicrobian Effects of the Essential Oil of Aniba rosaeodora: A Review of the Literature","authors":"Thaynara Monteiro Paiva Garcia, Mateus Silva Tavares, Renan Miranda Correa, Anthony Matheus dos Santos Gomes, Luana Nóbrega dos Santos, Anderson Lima Bentes, Rita de Cássia Silva de Oliveira","doi":"10.9734/ejmp/2024/v35i41193","DOIUrl":"https://doi.org/10.9734/ejmp/2024/v35i41193","url":null,"abstract":"Aims: Map the literature in search of the main biological and antimicrobial effects of the essential oil (EO) of Aniba rosaeodora. \u0000Study Design: This is an integrative review based on the PRISMA method. \u0000Place and Duration of Study: Center for Biological and Health Sciences of a University in the Brazilian Amazon, from January to August 2022. \u0000Methodology: A search was carried out in the main databases, such as Embase, Scopus, PubChem, PubMed, LILACS, SciELO and Portal BVS, with the descriptors consulted in the Medical Subject Headings (MeSH). \u0000Results: 134 articles were found and, after applying the inclusion and exclusion criteria, 17 were selected for full analysis. The EO of Aniba roseadora revealed mainly antibacterial, antifungal, antiparasitic and antiviral properties and in two studies, anesthetic effects, without observation of serious adverse events and deaths, were observed, but the specific active compound was not identified. The antibacterial activity of linalool, the compound most present in Aniba roseadora EO, was significant. Aniba roseadora EO also showed inhibitory and fungicidal potential. In addition, Aniba roseadora had an antidepressant effect, reducing anhedonia. \u0000Conclusion: The EO of Aniba rosaeadora showed potential biopharmacological and microbiological activities in pre-clinical models. Linalool stood out as the substance with the highest concentration in the EO; however, it is not yet known whether this compound is the main active component. Therefore, more studies should be conducted to support and describe the pharmacological potential of Aniba rosaeadora EO, leading to evidence-based pharmacology.","PeriodicalId":11969,"journal":{"name":"European journal of medicinal plants","volume":"14 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141340862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nutrient, Phytonutrient Composition, and Antioxidant Activity Analysis of Fresh and Cabinet Dried Coconut (Cocos nucifera L.) Inflorescence","authors":"Nikhila.P. Vinod, Jancy Rani D","doi":"10.9734/ejmp/2024/v35i41192","DOIUrl":"https://doi.org/10.9734/ejmp/2024/v35i41192","url":null,"abstract":"Background: Lately manufactories with medicinal properties play an important part in food and medicinal diligence for their capacities on disease prevention and treatment. Phytonutrients and antioxidant are the naturally occurring compounds found in the plant materials which has positive effects to avoid the oxidative stress-related diseases like cancer, cardiovascular disease, and diabetes. Antioxidant protects cells from the damage caused by the free radicals and to slow down or prevent oxidation of the other molecules. Antioxidants are extremely important in many plant base foods. Coconut (Cocos nucifera L.) inflorescence are rich in Phytonutrients and antioxidants. Nutrient are compound in the food which provide energy that facilitates repair, growth and also helps to carry out different life processes. They can help in reducing the risk of diseases and improves overall health. Hence for the objectives of the present study is to determine the nutrient composition and to estimate the phytonutrients and to analyse the antioxidant activity of fresh and the cabinet dry (45℃for 24h) Cocos nucifera (L.) inflorescence. \u0000Methods and Results: Nutrients such as carbohydrate (0.23g,0.19g), protein (24.7g,21.5g), fibre (11%,34.3%), iron(0.115mg,0.135), vitamin-C (0.01mcg,0.0062mcg), calcium (2.8mg,1.6mg) were analyzed by the AOAC method. The Preliminary qualitative phytonutrient analysis was carried out by the standard methodology with extraction of the plant material through the maceration process to identify the secondary metabolites like alkaloids, flavonoids, quinons, phenol, saponin, tannin, terpenoids and steroids in various solvents of aqueous, ethanol, methanol, acetone, petroleum ether and chloroform. Antioxidant activity were analyzed by the DPPH method. \u0000Conclusion: Cabinet dried sample have a better profile of the phytonutrients and antioxidant activity compared to fresh sample. So it is better to utilize cabinet dried sample in product development and supplementation of Cocos nucifera (L.) inflorescence.","PeriodicalId":11969,"journal":{"name":"European journal of medicinal plants","volume":"78 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141268446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Extraction and Purification of Squalene from Virgin Olive Oil via Catalytic Transesterification and Molecular Distillation","authors":"H. K. Manikyam, Dhanaseelan J, Jayaraj Mani","doi":"10.9734/ejmp/2024/v35i31191","DOIUrl":"https://doi.org/10.9734/ejmp/2024/v35i31191","url":null,"abstract":"Squalene, a highly valuable compound abundant in various natural sources, shows great potential in pharmaceutical, cosmetic, and nutraceutical applications. This research article outlines a comprehensive methodology for extracting and purifying squalene from virgin olive oil, a rich source of the compound. The extraction process begins with degumming, which involves heating the olive oil to 60-70°C to reduce viscosity, followed by the addition of 2-3% warm water to hydrate phospholipids. Food-grade phosphoric acid is then added to react with the phospholipids, forming precipitates. The mixture is stirred for 20-30 minutes and allowed to rest for an additional 20-30 minutes, enabling impurities to settle. The upper layer of degummed oil is separated via decantation or centrifugation and washed with warm water for pH adjustment. Next, transesterification is performed by mixing 100 ml of virgin olive oil with 25% methanol (w/w) and a catalyst (0.5% sodium methoxide or PTSA), and heating the mixture to 80-90°C under reflux for 1-2 hours. Following transesterification, the solvent and acetone are distilled out, and acetone precipitation is repeated 2-3 times to remove unsaponified matter, which is then filtered and evaporated. The concentrated oil undergoes molecular distillation at 180°C and 0.0033 bar pressure for 1 hour, yielding the distillate and residue for further analysis. Qualitative analysis using Thin Layer Chromatography (TLC) involves Merck TLC plates with silica gel 60 F254 and a hexane: chloroform (9:1) mobile phase. Spots are developed with a 10% HCl solution, confirming the presence of squalene with an RF value of 0.93. Quantitative analysis via High-Performance Thin-Layer Chromatography (HPTLC) employs Merck TLC plates with cyclohexane as the mobile phase and CAMAG at 254 nm and 366 nm wavelengths, revealing a squalene purity of 67% and a recovery rate of 69.8%. The initial purification through transesterification facilitated the conversion of ester groups, yielding squalene-rich fractions, while acetone precipitation effectively removed saponified matter. Molecular distillation further enhanced squalene purity. TLC analysis confirmed the qualitative presence of squalene, and HPTLC provided precise quantitative measurements. The obtained squalene purity of 67% significantly enriches the initial content in virgin olive oil, though further optimization could enhance purity and yield. Complementary techniques like GC-MS or HPLC could validate the purification process. This study presents an efficient, replicable procedure for extracting and purifying squalene from virgin olive oil, with significant implications for pharmaceutical, cosmetic, and nutraceutical industries. The findings support a sustainable and ethical shift towards vegetable-derived squalene, meeting market demands while ensuring high-quality production.","PeriodicalId":11969,"journal":{"name":"European journal of medicinal plants","volume":"29 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141272485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Djike Kouehiouon Justin Anderson-Bel, Zahoui Ouga Stanislas, Ekra Etchien N’dah Christelle, N. S. Anthelme, Flavien Traore
{"title":"Hypoglycaemic Effects of an Aqueous Leaves Extract of Combretum micranthum in Normoglycaemic Rats","authors":"Djike Kouehiouon Justin Anderson-Bel, Zahoui Ouga Stanislas, Ekra Etchien N’dah Christelle, N. S. Anthelme, Flavien Traore","doi":"10.9734/ejmp/2024/v35i31190","DOIUrl":"https://doi.org/10.9734/ejmp/2024/v35i31190","url":null,"abstract":"Background: In order to promote the Ivorian pharmacopoeia, we undertook the study of Combretum micranthum (Combretaceae), a plant commonly used in Ivory Coast for the treatment of diabetes. The aim of this study was to evaluate the hypoglycemic effects of an aqueous leaves extract of Combretum micranthum (EaqCM) in Wistar rats. \u0000Methods and Materials: A phytochemical screening study was performed. The pharmacological test on normoglycaemic rats was carried out in 4 groups of 5 rats per group. Rats in group 1 received 2 ml of distilled water, and rats in the test groups received doses ranging at 100 to 300 mg/kg B.W. of the EAqCM. Tests in pre-treated temporarily hyperglycemic rats were performed in 4 groups of 5 rats per group. The rats in groups 1 and 2 received 2ml of distilled water, the rats in test groups (3 and 4) received the dose of 10-2g/kg B.W. and 100 mg/kg B.W. respectively glibenclamide and EAqCM. Thirty minutes later, all rats except those in group 1 received anhydrous glucose. The protocol for testing post-treated hyperglycaemic rats is the same as that for pretreated rats, except that in this experiment glucose is administered to the animals before the test substances. Blood glucose is measured in the rats at regular intervals of 30, 60, 90, 120, 150, and 180 minutes after administration of the substances. \u0000Results: Qualitative phytochemical analysis of EAqCM revealed the presence of polyphenols, flavonoids, catechic, tannins, quinonic compounds, alkaloids, sterols, and polyterpenes. Pharmacological tests on the glycemia of normoglycemic rats showed that EAqCM has hypoglycemic properties at a dose of 100 mg/kgB.W. with a percentage reduction of 30%. In hyperglycemic rats, EAqCM and glibenclamide exhibited anti-hyperglycemic activity with respective percentages reduction of 57.47 % and 58.82 %. \u0000Conclusion: Antihyperglycemic effect of EAqCM in post-treated rats would probably be due to the presence of polyphenols and flavonoids in this extract. These results support the use of this plant in traditional medicine for the treatment of diabetes.","PeriodicalId":11969,"journal":{"name":"European journal of medicinal plants","volume":"77 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141021903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ouedraogo Rakiswendé Alexis, T. Basile, Azonbakin Azandégbé Simon, D. Maya, Ouedraogo Rakissida Alfred, Aweh A Bruno, Ouédraogo Aimé Sosthène, Yameogo Noé, Idani Boureima, Kouraogo M Paul, Kabore Jean Luc, Dabire Charlemagne, Ouedraogo Boris Honoré Amadou, Zouré Abdou Azaque, Ouédraogo W. H. Gautier, B. Balé, Sanou/Lamien Assita
{"title":"Effects of Ficus capensis Leaves Aqueous Extracts (Lactogenic Medicinal Plant) on NMRI Mice Milk Secretion","authors":"Ouedraogo Rakiswendé Alexis, T. Basile, Azonbakin Azandégbé Simon, D. Maya, Ouedraogo Rakissida Alfred, Aweh A Bruno, Ouédraogo Aimé Sosthène, Yameogo Noé, Idani Boureima, Kouraogo M Paul, Kabore Jean Luc, Dabire Charlemagne, Ouedraogo Boris Honoré Amadou, Zouré Abdou Azaque, Ouédraogo W. H. Gautier, B. Balé, Sanou/Lamien Assita","doi":"10.9734/ejmp/2024/v35i21184","DOIUrl":"https://doi.org/10.9734/ejmp/2024/v35i21184","url":null,"abstract":"Introduction: Ficus capensis is a plant used in traditional medicine to stimulate lactation in women and animals in Africa. However, the effects of their extracts on the mammary gland are poorly documented. The objective of the study was to evaluate the effects of Ficus capensis leaves aqueous extracts on NMRI mice milk secretion.\u0000Methodology: This was an experimental animal study using virgin female NMRI mice aged eight to ten weeks. The mice were grouped into for groups of eight mice each. Each group received one of the following products: distilled water, Galactogil™, sulpiride, aqueous extracts (AE) of capensis leaves. Data were analysed and processed using Microsoft Excel 2016 and Stata MP 16 with P ≤ .05 as the significance threshold.\u0000Results: Arborescence of the galactophorous ducts was more developed in the sulpiride lot. Galactogil™, and capensis leaves extracts treated groups showed almost equivalent arborescence with a higher tendency than the distilled water. With histological haematin- eosin staining, the ratio of galactophorous ducts containing secretions to total ducts was higher in the groups of Ficus capensis AE treated group than distilled water (P = .0001). Galactogil™, sulpiride and the group of Ficus capensis extracts each had higher levels of beta-casein in mammary tissue and average prolactinemia than distilled water (P < .01). Mammary tissue stained by immunohistochemistry with anti-prolactin receptor antibodies showed more intensely labelled mammary glands in the sulpiride and Ficus capensis extracts groups. There was no statistically significant difference between average progesteronemia among the different groups.\u0000Conclusion: F. capensis leaves AE administered to virgin female NMRI mice showed lactogenic and mammogenic effects. The extracts were able to increase the nutritional quality of the milk produced, as evidenced by the increase in protein secretion.","PeriodicalId":11969,"journal":{"name":"European journal of medicinal plants","volume":"2 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140654318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Navin Kumar Mahato, Kalpana Prasad, Arun Kumar Roy Mahato
{"title":"Phytochemical Profiling of Aqueous Methanol Extract of Terminalia bellirica from Bokaro District of Jharkhand, India","authors":"Navin Kumar Mahato, Kalpana Prasad, Arun Kumar Roy Mahato","doi":"10.9734/ejmp/2024/v35i21183","DOIUrl":"https://doi.org/10.9734/ejmp/2024/v35i21183","url":null,"abstract":"Plants are a vital source of medicine for human being from ancient times. Various plant parts are highly medicinal due to the presence of different bioactive compounds and secondary metabolites. Many of these compounds present in medicinal plants are unknown to the scientific community. T. bellirica is distributed in tropical parts of the world and is a known ethnomedicinal plant that is the reservoir of various bioactive compounds. The present investigated the bioactive and secondary metabolite present in the fruits of T. bellirica collected from the Bokaro district and has been analysed using Gas chromatography-Mass spectrometry analysis. The investigation found 55 compounds from the methanol extract of the fruit sample of T. bellirica. Among the recorded compounds, Pyrogallol is the major constituent with 85% area in the chromatogram, followed by 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one (DDMP)with 5% area, and the rest of the compounds are altogether 10% of the total. In conclusion, the present study recorded and highlighted a total of 55 bioactive compounds from the dry fruits and pericarp, which is more than a double of the compounds earlier known from the plant species. Further, among the recorded biochemical compounds, the concentration of Pyrogallol was alone more than 85% of the total compounds found from the methanol extract of the fruit sample of T. bellirica.","PeriodicalId":11969,"journal":{"name":"European journal of medicinal plants","volume":"12 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140711650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. A. Baah, Akwasi Acheampong, I. Amponsah, R. Nketia
{"title":"Antiplasmodial Activity and Phytochemical Evaluation of the Stems of Albizia coriaria and Ficus sur","authors":"K. A. Baah, Akwasi Acheampong, I. Amponsah, R. Nketia","doi":"10.9734/ejmp/2024/v35i21179","DOIUrl":"https://doi.org/10.9734/ejmp/2024/v35i21179","url":null,"abstract":"Background: Malaria continues to cause havoc on various populations because of the high mortality and economic burden associated with the disease. Progress made in the therapeutics of the disease is threatened by the emerging parasite resistance to currently used first line treatment drugs. This has prompted the search for new, effective, and safe antimalarial agents. The use of traditional medicine in the treatment of various types of diseases including malaria is a regular practice seen with many cultures in Ghana. The stems of Albizia coriaria Welw ex. Oliver and Ficus sur Forssk are such plants used with little evidence about their in vivo efficacy.\u0000Aim: This study therefore aimed to assess the in vivo antiplasmodial potential, and the acute toxicity of the hydroethanolic stem extract of Albizia coriaria and Ficus sur.\u0000Method: Qualitative phytochemical screening was done on the powdered plant material using standard methods. Acute toxicity was carried out according to OECD guidelines using the Limit test. In vivo antiplasmodial activity of the hydroethanolic extract was assessed using the Peter’s 4-day suppressive and Rane’s curative test.\u0000Results: The 70% ethanol extract was safe with the lethal dose above 3000 mg/kg. All the extracts significantly (P < 0.05) suppressed parasitaemia in the Peter’s suppressive and Rane’s curative test with Albizia coriaria producing the highest chemotherapeutic activity of 68.89 and 61.46% in the suppressive and curative test respectively. That of F. sur was less than 50% in both assays. Artesunate reference drug recorded over 80% suppression in the curative test but lesser activity in the suppression assay compared to A. coriaria. Several plant metabolites including terpenoids, flavonoids and coumarins were found in both plant samples.\u0000Conclusion: Albizia coriaria and Ficus sur 70% ethanol extract showed considerable antiplasmoidal activity and were found to be non-toxic in acute toxicity study, thus justifying their safe use in the treatment of malaria as suggested by folklore medicine.","PeriodicalId":11969,"journal":{"name":"European journal of medicinal plants","volume":"15 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140753858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Studies on Chemical Changes in Burfi Enriched with different Herbs","authors":"Meshram, B.D., Rokade Apeksha, Shaikh Adil","doi":"10.9734/ejmp/2024/v35i11180","DOIUrl":"https://doi.org/10.9734/ejmp/2024/v35i11180","url":null,"abstract":"The investigation was carried out to study the chemical changes taking place in burfi by the addition of several herbs and their comparison with the control product. Different herbs, viz., Withania somnifera (Ashwgandha), Asparagus racemosus (Shatavari), and Ocimum sanctum (Tulsi), were incorporated into the blend in the ratio of 5:4:1, respectively, to develop herbal burfi. The combination of herbs was added at levels of 1.00, 1.25, 1.50, and 2.00% by weight of khoa to obtain products designated T1, T2, T3, and T4, respectively. The control product (T0) was prepared in a similar manner but was devoid of herbs. Proximate analysis, including moisture, total solids, fat, lactose, protein, and ash, was conducted. The results show that moisture content decreased significantly (P≤0.05) with increasing herb addition, while total solids increased. Protein content increased with higher herb percentages, likely due to the protein content of the added herbs. Fat and lactose content remained unchanged with herb addition, as herbs do not contribute significantly to these components. Ash content increased with higher herb addition rates, though not significantly (P≥0.05). Overall, the addition of herbs influenced the chemical composition of burfi, impacting moisture, total solids, protein, and ash content with varying degrees of significance.","PeriodicalId":11969,"journal":{"name":"European journal of medicinal plants","volume":"113 28","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140380302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}