{"title":"Correction to: Screening for dilated cardiomyopathy in immediate family members: to whom, how, when (and where).","authors":"","doi":"10.1093/eurheartjsupp/suae080","DOIUrl":"https://doi.org/10.1093/eurheartjsupp/suae080","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1093/eurheartjsupp/suae024.].</p>","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":"26 Suppl 1","pages":"suae080"},"PeriodicalIF":1.6,"publicationDate":"2024-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11110454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141087486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Irma Bisceglia, Elio Venturini, Maria Laura Canale, Marco Ambrosetti, Carmine Riccio, Francesco Giallauria, Giuseppina Gallucci, Maurizio G Abrignani, Giulia Russo, Chiara Lestuzzi, Raffaella Mistrulli, Giovanni De Luca, Fabio Maria Turazza, Gianfrancesco Mureddu, Stefania Angela Di Fusco, Fabiana Lucà, Leonardo De Luca, Andrea Camerini, Geza Halasz, Massimiliano Camilli, Vincenzo Quagliariello, Nicola Maurea, Francesco Fattirolli, Michele Massimo Gulizia, Domenico Gabrielli, Massimo Grimaldi, Furio Colivicchi, Fabrizio Oliva
{"title":"Cardio-oncology rehabilitation: are we ready?","authors":"Irma Bisceglia, Elio Venturini, Maria Laura Canale, Marco Ambrosetti, Carmine Riccio, Francesco Giallauria, Giuseppina Gallucci, Maurizio G Abrignani, Giulia Russo, Chiara Lestuzzi, Raffaella Mistrulli, Giovanni De Luca, Fabio Maria Turazza, Gianfrancesco Mureddu, Stefania Angela Di Fusco, Fabiana Lucà, Leonardo De Luca, Andrea Camerini, Geza Halasz, Massimiliano Camilli, Vincenzo Quagliariello, Nicola Maurea, Francesco Fattirolli, Michele Massimo Gulizia, Domenico Gabrielli, Massimo Grimaldi, Furio Colivicchi, Fabrizio Oliva","doi":"10.1093/eurheartjsupp/suae030","DOIUrl":"10.1093/eurheartjsupp/suae030","url":null,"abstract":"<p><p>Cardio-oncology rehabilitation (CORE) is not only an essential component of cancer rehabilitation but also a pillar of preventive cardio-oncology. Cardio-oncology rehabilitation is a comprehensive model based on a multitargeted approach and its efficacy has been widely documented; when compared with an 'exercise only' programme, comprehensive CORE demonstrates a better outcome. It involves nutritional counselling, psychological support, and cardiovascular (CV) risk assessment, and it is directed to a very demanding population with a heavy burden of CV diseases driven by physical inactivity, cancer therapy-induced metabolic derangements, and cancer therapy-related CV toxicities. Despite its usefulness, CORE is still underused in cancer patients and we are still at the dawning of remote models of rehabilitation (tele-rehabilitation). Not all CORE is created equally: a careful screening procedure to identify patients who will benefit the most from CORE and a multidisciplinary customized approach are mandatory to achieve a better outcome for cancer survivors throughout their cancer journey. The aim of this paper is to provide an updated review of CORE not only for cardiologists dealing with this peculiar population of patients but also for oncologists, primary care providers, patients, and caregivers. This multidisciplinary team should help cancer patients to maintain a healthy and active life before, during, and after cancer treatment, in order to improve quality of life and to fight health inequities.</p>","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":"26 Suppl 2","pages":"ii252-ii263"},"PeriodicalIF":1.6,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11110456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141087522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fabiana Lucà, Daniela Pavan, Michele Massimo Gulizia, Maria Teresa Manes, Maurizio Giuseppe Abrignani, Francesco Antonio Benedetto, Irma Bisceglia, Silvana Brigido, Pasquale Caldarola, Raimondo Calvanese, Maria Laura Canale, Giorgio Caretta, Roberto Ceravolo, Alaide Chieffo, Cristina Chimenti, Stefano Cornara, Ada Cutolo, Stefania Angela Di Fusco, Irene Di Matteo, Concetta Di Nora, Francesco Fattirolli, Silvia Favilli, Giuseppina Maura Francese, Sandro Gelsomino, Giovanna Geraci, Simona Giubilato, Nadia Ingianni, Annamaria Iorio, Francesca Lanni, Andrea Montalto, Federico Nardi, Alessandro Navazio, Martina Nesti, Iris Parrini, Annarita Pilleri, Andrea Pozzi, Carmelo Massimiliano Rao, Carmine Riccio, Roberta Rossini, Pietro Scicchitano, Serafina Valente, Giuseppe Zuccalà, Domenico Gabrielli, Massimo Grimaldi, Furio Colivicchi, Fabrizio Oliva
{"title":"Italian Association of Hospital Cardiologists Position Paper 'Gender discrepancy: time to implement gender-based clinical management'.","authors":"Fabiana Lucà, Daniela Pavan, Michele Massimo Gulizia, Maria Teresa Manes, Maurizio Giuseppe Abrignani, Francesco Antonio Benedetto, Irma Bisceglia, Silvana Brigido, Pasquale Caldarola, Raimondo Calvanese, Maria Laura Canale, Giorgio Caretta, Roberto Ceravolo, Alaide Chieffo, Cristina Chimenti, Stefano Cornara, Ada Cutolo, Stefania Angela Di Fusco, Irene Di Matteo, Concetta Di Nora, Francesco Fattirolli, Silvia Favilli, Giuseppina Maura Francese, Sandro Gelsomino, Giovanna Geraci, Simona Giubilato, Nadia Ingianni, Annamaria Iorio, Francesca Lanni, Andrea Montalto, Federico Nardi, Alessandro Navazio, Martina Nesti, Iris Parrini, Annarita Pilleri, Andrea Pozzi, Carmelo Massimiliano Rao, Carmine Riccio, Roberta Rossini, Pietro Scicchitano, Serafina Valente, Giuseppe Zuccalà, Domenico Gabrielli, Massimo Grimaldi, Furio Colivicchi, Fabrizio Oliva","doi":"10.1093/eurheartjsupp/suae034","DOIUrl":"10.1093/eurheartjsupp/suae034","url":null,"abstract":"<p><p>It has been well assessed that women have been widely under-represented in cardiovascular clinical trials. Moreover, a significant discrepancy in pharmacological and interventional strategies has been reported. Therefore, poor outcomes and more significant mortality have been shown in many diseases. Pharmacokinetic and pharmacodynamic differences in drug metabolism have also been described so that effectiveness could be different according to sex. However, awareness about the gender gap remains too scarce. Consequently, gender-specific guidelines are lacking, and the need for a sex-specific approach has become more evident in the last few years. This paper aims to evaluate different therapeutic approaches to managing the most common women's diseases.</p>","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":"26 Suppl 2","pages":"ii264-ii293"},"PeriodicalIF":1.6,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11110461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141087524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stefania Angela Di Fusco, Edoardo Mocini, Mauro Gori, Massimo Iacoviello, Claudio Bilato, Marco Corda, Leonardo De Luca, Massimo Di Marco, Giovanna Geraci, Attilio Iacovoni, Massimo Milli, Alessandro Navazio, Vittorio Pascale, Carmine Riccio, Pietro Scicchitano, Emanuele Tizzani, Domenico Gabrielli, Massimo Grimaldi, Furio Colivicchi, Fabrizio Oliva
{"title":"Italian Association of Hospital Cardiologists position paper-obesity in adults: a clinical primer.","authors":"Stefania Angela Di Fusco, Edoardo Mocini, Mauro Gori, Massimo Iacoviello, Claudio Bilato, Marco Corda, Leonardo De Luca, Massimo Di Marco, Giovanna Geraci, Attilio Iacovoni, Massimo Milli, Alessandro Navazio, Vittorio Pascale, Carmine Riccio, Pietro Scicchitano, Emanuele Tizzani, Domenico Gabrielli, Massimo Grimaldi, Furio Colivicchi, Fabrizio Oliva","doi":"10.1093/eurheartjsupp/suae031","DOIUrl":"10.1093/eurheartjsupp/suae031","url":null,"abstract":"<p><p>Obesity is a chronic and relapsing disease characterized by the interaction between individual predispositions and an obesogenic environment. Recent advances in understanding the mechanisms of energetic homoeostasis paved the way to more effective therapeutic approaches compared with traditional treatments. Since obesity is a complex disease, it necessitates a multi-disciplinary approach whose implementation remains challenging. Nonetheless, emerging pharmacological interventions appear promising. Currently, therapeutic success is discreet in the short term but often fails to maintain long-term weight loss due to a high likelihood of weight regain. Cardiologists play a key role in managing patients with obesity, yet often lack familiarity with its comprehensive management. The aim of this document is to summarize knowledge to consolidate essential knowledge for clinicians to effectively treat patients living with obesity. The paper emphasizes the pivotal role of a strong patient-clinician relationship in navigating successful treatment. We analyse the criteria commonly used to diagnose obesity and point out the strengths and limitations of different criteria. Furthermore, we discuss the role of obesiologists and the contributions of cardiologists. In addition, we detail key components of effective therapeutic strategies, including educational aspects and pharmacological options.</p>","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":"26 Suppl 2","pages":"ii221-ii235"},"PeriodicalIF":1.6,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11110455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141087527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leonardo De Luca, Francesco Rocco Pugliese, Beniamino Susi, Alessandro Navazio, Marco Corda, Andrea Fabbri, Pietro Scicchitano, Antonio Voza, Simone Vanni, Claudio Bilato, Giovanna Geraci, Domenico Gabrielli, Massimo Grimaldi, Furio Colivicchi, Fabio De Iaco, Fabrizio Oliva
{"title":"ANMCO/SIMEU consensus document on the use of reversal agents for antithrombotic therapies in patients with ongoing bleeding or at high risk of haemorrhagic events.","authors":"Leonardo De Luca, Francesco Rocco Pugliese, Beniamino Susi, Alessandro Navazio, Marco Corda, Andrea Fabbri, Pietro Scicchitano, Antonio Voza, Simone Vanni, Claudio Bilato, Giovanna Geraci, Domenico Gabrielli, Massimo Grimaldi, Furio Colivicchi, Fabio De Iaco, Fabrizio Oliva","doi":"10.1093/eurheartjsupp/suae033","DOIUrl":"10.1093/eurheartjsupp/suae033","url":null,"abstract":"<p><p>In recent decades, an incredible evolution in antithrombotic therapies used for treating patients with atherosclerosis, atrial fibrillation, and venous thromboembolism has been observed, leading to the availability of increasingly safe drugs. Nonetheless, bleeding complications remain a significant concern, with considerable health, social, and economic implications. To improve the acute management of patients experiencing or at risk for major bleeding events, specific reversal agents for antithrombotic drugs have been recently developed. While these agents demonstrate effectiveness in small-scale pharmacodynamic studies and clinical trials, it is imperative to balance the benefits of reversing antiplatelet or anticoagulant therapy against the risk of prothrombotic effects. These risks include the potential loss of antithrombotic protection and the prothrombotic tendencies associated with bleeding, major surgery, or trauma. This joint document of the Italian Association of Hospital Cardiologists (<i>Associazione Nazionale Medici Cardiologi Ospedalieri</i>) and the Italian Society of Emergency Medicine (<i>Società Italiana di Medicina d'Emergenza-Urgenza</i>) delineates the key features and efficacy of available reversal agents. It also provides practical flowcharts to guide their use in patients with active bleeding or those at elevated risk of major bleeding events.</p>","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":"26 Suppl 2","pages":"ii211-ii220"},"PeriodicalIF":1.6,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11110459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141087489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leonardo De Luca, Stefania Angela Di Fusco, Gianmarco Iannopollo, Raffaella Mistrulli, Vittoria Rizzello, Alberto Aimo, Alessandro Navazio, Claudio Bilato, Marco Corda, Massimo Di Marco, Giovanna Geraci, Attilio Iacovoni, Massimo Milli, Vittorio Pascale, Carmine Riccio, Pietro Scicchitano, Emanuele Tizzani, Domenico Gabrielli, Massimo Grimaldi, Furio Colivicchi, Fabrizio Oliva
{"title":"Associazione Nazionale Medici Cardiologi Ospedalieri (ANMCO) scientific statement on the simplification of the drug regimen for secondary cardiovascular prevention.","authors":"Leonardo De Luca, Stefania Angela Di Fusco, Gianmarco Iannopollo, Raffaella Mistrulli, Vittoria Rizzello, Alberto Aimo, Alessandro Navazio, Claudio Bilato, Marco Corda, Massimo Di Marco, Giovanna Geraci, Attilio Iacovoni, Massimo Milli, Vittorio Pascale, Carmine Riccio, Pietro Scicchitano, Emanuele Tizzani, Domenico Gabrielli, Massimo Grimaldi, Furio Colivicchi, Fabrizio Oliva","doi":"10.1093/eurheartjsupp/suae032","DOIUrl":"10.1093/eurheartjsupp/suae032","url":null,"abstract":"<p><p>The issue of suboptimal drug regimen adherence in secondary cardiovascular prevention presents a significant barrier to improving patient outcomes. To address this, the utilization of drug combinations, specifically single pill combinations (SPCs) and polypills, was proposed as a strategy to simplify treatment regimens. This approach aims to enhance treatment accessibility, affordability, and adherence, thereby reducing healthcare costs and improving patient health. The document is an Associazione Nazionale Medici Cardiologi Ospedalieri (ANMCO) scientific statement on simplifying drug regimens for secondary cardiovascular prevention. It discusses the underuse of treatments despite available, effective, and accessible options, highlighting a significant gap in secondary prevention across different socio-economic statuses and countries. The statement explores barriers to implementing evidence-based treatments, including patient, healthcare provider, and system-related challenges. The paper also reviews international guidelines, the role of SPCs and polypills in clinical practice, and their economic impact, advocating for their use in secondary prevention to improve patient outcomes and adherence.</p>","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":"26 Suppl 2","pages":"ii236-ii251"},"PeriodicalIF":1.6,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11110452/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141087517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexander M Bernhardt, Evgenij Potapov, Christophe Vandenbriele, Carsten Skurk, Letizia F Bertoldi, Federico Pappalardo
{"title":"Differential utilization of Impella devices, extracorporeal membrane oxygenation, and combined therapies as escalation and de-escalation strategies.","authors":"Alexander M Bernhardt, Evgenij Potapov, Christophe Vandenbriele, Carsten Skurk, Letizia F Bertoldi, Federico Pappalardo","doi":"10.1093/eurheartjsupp/suad131","DOIUrl":"https://doi.org/10.1093/eurheartjsupp/suad131","url":null,"abstract":"<p><p>Cardiogenic shock (CS) is a life-threatening condition characterized by a state of inadequate systemic tissue perfusion caused by cardiac dysfunction. When to implement, change, or remove the use of a temporary mechanical circulatory support (tMCS) in patients with CS is dependent on the aetiology and severity. Here, patient scenarios underlying the need to escalate, de-escalate, wean, or bridge from tMCS devices are taken into consideration by interdisciplinary heart failure and CS teams. This includes a comprehensive review of and focus on the rationale for specific device escalation and de-escalation strategies, device selection, and general management.</p>","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":"25 Suppl I","pages":"I32-I38"},"PeriodicalIF":1.6,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10715938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138799225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Letizia F Bertoldi, Andrea Montisci, Dirk Westermann, Mario Iannaccone, Vasileios Panoulas, Nikos Werner, Norman Mangner
{"title":"From medical therapy to mechanical support: strategies for device selection and implantation techniques.","authors":"Letizia F Bertoldi, Andrea Montisci, Dirk Westermann, Mario Iannaccone, Vasileios Panoulas, Nikos Werner, Norman Mangner","doi":"10.1093/eurheartjsupp/suad128","DOIUrl":"https://doi.org/10.1093/eurheartjsupp/suad128","url":null,"abstract":"<p><p>Cardiogenic shock (CS) is a complex clinical syndrome with a high risk of mortality. The recent, rapid development of temporary mechanical circulatory support (tMCS) has altered CS treatment. While catecholamines remain the cornerstone of CS therapy, tMCS usage has increased. According to shock severity, different treatment strategies including catecholamines alone, catecholamines and tMCS, or multiple tMCS might be used. State-of-the-art implantation techniques are necessary to avoid complications linked to the invasive nature of tMCS. In particular, bleeding and access-site complications might counteract the potential haemodynamic benefit of a percutaneous ventricular assist device. In this review, we describe the role of catecholamines in CS treatment and present the different tMCS devices with an explanation on how to use them according to CS aetiology and severity. Finally, an overview of the best practice for device implantation is provided.</p>","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":"25 Suppl I","pages":"I11-I18"},"PeriodicalIF":1.6,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10715943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138799241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jacob Eifer Moller, Norman Mangner, Federico Pappalardo, Holger Thiele
{"title":"Glimpse into the future.","authors":"Jacob Eifer Moller, Norman Mangner, Federico Pappalardo, Holger Thiele","doi":"10.1093/eurheartjsupp/suad133","DOIUrl":"10.1093/eurheartjsupp/suad133","url":null,"abstract":"<p><p>Randomized studies attempting to prove benefit of mechanical circulatory support in cardiogenic shock have failed to reduce the risk of death. Further, both registry and randomized data suggest increased rates of serious complications associated with these devices. This last review in the supplement discusses current evidence and provides a perspective on how the scientific community could advance cardiogenic shock research focused on mechanical circulatory support.</p>","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":"25 Suppl I","pages":"I44-I48"},"PeriodicalIF":1.7,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10715941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138799245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}