European Heart Journal Supplements最新文献

{"title":"Frontiers in conduction system pacing: treatment of long PR in patients with heart failure.","authors":"Nandita Kaza, Daniel Keene, Pugazhendhi Vijayaraman, Zachary Whinnett","doi":"10.1093/eurheartjsupp/suad116","DOIUrl":"10.1093/eurheartjsupp/suad116","url":null,"abstract":"<p><p>Patients with heart failure who have a prolonged PR interval are at a greater risk of adverse clinical outcomes than those with a normal PR interval. Potential mechanisms of harm relating to prolonged PR intervals include reduced ventricular filling and also the potential progression to a higher degree heart block. There has, however, been relatively little work specifically focusing on isolated PR prolongation as a therapeutic target. Secondary analyses of trials of biventricular pacing in heart failure have suggested that PR prolongation is both a prognostic marker and a promising treatment target. However, while biventricular pacing offers an improved activation pattern, it is nonetheless less physiological than native conduction in patients with a narrow QRS duration, and thus, may not be the ideal option for achieving therapeutic shortening of atrioventricular delay. Conduction system pacing aims to preserve physiological ventricular activation and may therefore be the ideal method for ventricular pacing in patients with isolated PR prolongation. Acute haemodynamic experiments and the recently reported His-optimized pacing evaluated for heart failure (HOPE HF) Randomised Controlled Trial demonstrates the potential benefits of physiological ventricular pacing on patient symptoms and left ventricular function in patients with heart failure.</p>","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134648678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new era of physiologic cardiac pacing.","authors":"Haran Burri, Pugazhendhi Vijayaraman","doi":"10.1093/eurheartjsupp/suad120","DOIUrl":"10.1093/eurheartjsupp/suad120","url":null,"abstract":"","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134648675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alternative atrial pacing site to improve cardiac function: focus on Bachmann's bundle pacing.","authors":"Edmond M Cronin, Natasha Vedage, Carsten W Israel","doi":"10.1093/eurheartjsupp/suad118","DOIUrl":"10.1093/eurheartjsupp/suad118","url":null,"abstract":"<p><p>Pacing from the right atrial appendage (RAA) prolongs the P wave duration and can induce interatrial and especially left-sided atrio-ventricular dyssynchrony. Pacing from Bachmann's bundle closely reproduces normal physiology and has the potential to avoid the electromechanical dysfunction associated with conventional RAA pacing. Interatrial conduction delay is associated with an increased risk of stroke, heart failure, and death. In addition to a reduction in atrial fibrillation, Bachmann's bundle pacing has emerging applications as a hemodynamic pacing modality. This review outlines the pathophysiology of atrial conduction disturbances and their potential remedies and provides the reader with a practical guide to implementing Bachmann's bundle pacing with an emphasis on the recapitulation of normal electrical and mechanical function.</p>","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134648676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of conduction system pacing in ablate and pace strategies for atrial fibrillation.","authors":"Roderick Tung, Haran Burri","doi":"10.1093/eurheartjsupp/suad119","DOIUrl":"https://doi.org/10.1093/eurheartjsupp/suad119","url":null,"abstract":"<p><p>With the advent of conduction system pacing, the threshold for performing 'ablate and pace' procedures for atrial fibrillation has gone down markedly in many centres due to the ability to provide a simple and physiological means of pacing the ventricles. This article reviews the technical considerations for this strategy as well as the current evidence, recognized indications, and future perspectives.</p>","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637833/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134648681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implant, assessment, and management of conduction system pacing.","authors":"Kevin Vernooy, Daniel Keene, Weijian Huang, Pugazhendhi Vijayaraman","doi":"10.1093/eurheartjsupp/suad115","DOIUrl":"https://doi.org/10.1093/eurheartjsupp/suad115","url":null,"abstract":"<p><p>His bundle pacing and left bundle branch pacing, together referred to as conduction system pacing, have (re)gained considerable interest over the past years as it has the potential to preserve and/or restore a more physiological ventricular activation when compared with right ventricular pacing and may serve as an alternative for cardiac resynchronization therapy. This review manuscript dives deeper into the implantation techniques and the relevant anatomy of the conduction system for both pacing strategies. Furthermore, the manuscript elaborates on better understanding of conduction system capture with its various capture patterns, its potential complications as well as appropriate follow-up care. Finally, the limitations and its impact on clinical care for both His bundle pacing and left bundle branch pacing are being discussed.</p>","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134648679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personalized accelerated physiologic pacing.","authors":"Markus Meyer, Margaret Infeld, Nicole Habel, Daniel Lustgarten","doi":"10.1093/eurheartjsupp/suad117","DOIUrl":"10.1093/eurheartjsupp/suad117","url":null,"abstract":"<p><p>Heart failure with preserved ejection fraction (HFpEF) is increasingly prevalent with a high socioeconomic burden. Pharmacological heart rate lowering was recommended to improve ventricular filling in HFpEF. This article discusses the misperceptions that have resulted in an overprescription of beta-blockers, which in all likelihood have untoward effects on patients with HFpEF, even if they have atrial fibrillation or coronary artery disease as a comorbidity. Directly contradicting the lower heart rate paradigm, faster heart rates provide haemodynamic and structural benefits, amongst which lower cardiac filling pressures and improved ventricular capacitance may be most important. Safe delivery of this therapeutic approach is feasible with atrial and ventricular conduction system pacing that aims to emulate or enhance cardiac excitation to maximize the haemodynamic benefits of accelerated pacing. This conceptual framework was first tested in the myPACE randomized controlled trial of patients with pre-existing pacemakers and preclinical or overt HFpEF. This article provides the background and path towards this treatment approach.</p>","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10637836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134648680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Diagnostic and prognostic electrocardiographic features in patients with hypertrophic cardiomyopathy.","authors":"","doi":"10.1093/eurheartjsupp/suad121","DOIUrl":"https://doi.org/10.1093/eurheartjsupp/suad121","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1093/eurheartjsupp/suad074.].</p>","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f1/a5/suad121.PMC10506374.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41120345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to: In pursuit of balance: RAASi and hyperkalemia treatment.","authors":"Edoardo Sciatti,&nbsp;Emilia D'Elia,&nbsp;Giulio Balestrieri,&nbsp;Salvatore D'Isa,&nbsp;Attilio Iacovoni,&nbsp;Michele Senni","doi":"10.1093/eurheartjsupp/suad122","DOIUrl":"https://doi.org/10.1093/eurheartjsupp/suad122","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1093/eurheartjsupp/suad053.].</p>","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506377/pdf/suad122.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41178368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Steps to bridge the gap for better kidney care for cardiac nurses","authors":"Mohamed El-Khatib, Hassan Elsayed, Mohamed Kandel, Saber Mostafa","doi":"10.1093/eurheartjsupp/suad113.014","DOIUrl":"https://doi.org/10.1093/eurheartjsupp/suad113.014","url":null,"abstract":"Abstract Background Kidney diseases have been identified as a major threat to patients with cardiac diseases as they can affect 50% of patients with cardiovascular diseases stages 4 and 5. World Kidney Day (WKD) is a global campaign aimed at raising the awareness of the importance of our kidneys. Aim Aswan Heart Centre was celebrating WKD by conducting an educational awareness day aiming to enhance and fill the knowledge gap for healthcare workers and patients. Process This event was divided as follows:Patients and families: nurses in different departments of the facility ran several educational sessions, and patients group discussions to promote the wellbeing of patients and families regarding the Chronic Kidney Disease (CKD) and the 8 golden rules through the utilization of some interactive materials such as videos and educational posters written in Arabic.Healthcare workers: An online session was conducted for all nurses in Aswan Heart Centre to enhance the knowledge background regarding chronic kidney disease. Furthermore, an online survey was completed by the nurses to assess the current understanding of the chronic kidney disease prior the online session. Graph1. Survey result 71 nursing staff took the survey. Data analysis Most of the staff were aware about the kidney health as the average of the correctly answered questions is 67.25% as shown in Chart 1. Recommendation Such event raises the awareness about our kidneys and encourage patients for systematic screening. Additional Content An author video to accompany this abstract is available on https://academic.oup.com/eurheartjsupp. Please click on the arrow next to ‘More Content’ and then click on ‘Author videos’.","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135298208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of epicardial adipose tissue on coronary arteries thrombus burden and early outcomes in STEMI patients","authors":"Gehan Magdy Yousef, Mahmoud Muhamed Hassanein, Aly Alsaid Zidan, Diaaaldin Taha Zahran","doi":"10.1093/eurheartjsupp/suad113.009","DOIUrl":"https://doi.org/10.1093/eurheartjsupp/suad113.009","url":null,"abstract":"Abstract Aim Evaluation the relationship between the epicardial adipose tissue thickness (EAT), the coronary arteries thrombus burden and the early major adverse cardiovascular events (MACE) in patients presented with STEMI undergoing primary percutaneous coronary intervention. Method The study was prospective and included patients (n = 80) who were referred to the cardiology department in Alexandria University Hospitals with STEMI between the 1st of March 2021 and the last day of August 2022. Patient clinical, laboratory, angiographic and echocardiographic data were described. Patients were put under observation to detect the occurrence of any major adverse cardiovascular events either in hospital or during a period of 30 days follow up. Special concerns for measuring EAT as an echo free space between the myocardium and visceral epicardial and measured perpendicular to the free wall of the right ventricle in parasternal long and short axis views at end diastole and angiographic assessment of thrombus burden was scored as follows: 0 (no thrombus), 1 (possible thrombus), 2 (definite thrombus &amp;lt; 0.5× reference vessel diameter), 3 (definite thrombus 0.5–2× reference vessel diameter), 4 (definite thrombus &amp;gt;2× reference vessel diameter), and 5 (complete vessel occlusion). According to thrombus grade the patients were grouped as low thrombus burden (grades 0–3) and high thrombus burden (grades 4 and 5). Results 25 subjects were in the low thrombus burden group and 55 in the high thrombus burden group. There were no differences in the two groups for age, sex, smoking and drug addiction status, family history of coronary artery disease, diabetes mellitus, hypertension, and total cholesterol, triglyceride, LDL-C and HDL-C, The mean Wall motion score and Wall motion score index. The means levels of high sensitivity troponin I and Creatine Kinase MB are measured higher in the low thrombus burden group with statistically significant difference (P = 0.025) and (P = 0.032). Balloon predilation was statistically significant difference between the two groups (P = 0.006). Thrombus’ aspiration, balloon post dilation of the culprit vessel, GpIIb/IIIa inhibitors, and one stent only were insignificant difference between the two groups. The receiver operating characteristic curve analysis was undergone to determine the cutoff value of EAT to predict the presence of high thrombus burden setting a significance level at P &amp;lt; 0.05. The thickness of 2.48 mm for EAT has 74.55% sensitivity and 72.0% specificity for prediction of the high thrombus burden. The predictors of the high thrombus burden were analyzed by univariate analysis shows EAT, the waist circumference, Wight, the body mass index, and balloon predilation were found as an independent predictors of high thrombus burden. The multivariate analysis shows EAT and balloon predilation were found as an independent predictors of high thrombus burden. The overall MACE at 30 day follows up has statistic","PeriodicalId":11956,"journal":{"name":"European Heart Journal Supplements","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135299072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}