Journal of Biology and Today`s World最新文献

{"title":"A study of the effect of curcumin on plasma free radicals in cirrhotic rats using Bile Duct Ligation (BDL)","authors":"Davoud Javidmehr, A. Moradi, Alireza Karimoalah, Hadi Zarezrdini, Hamidreza Shahmoradi, Khadije Arabbadkobe, Akbar Rezai-Chahoki, Tahere Barabadi, F. Ahmadian","doi":"10.15412/J.JBTW.01040802","DOIUrl":"https://doi.org/10.15412/J.JBTW.01040802","url":null,"abstract":"\"Cirrhosis of the liver is an important cause of mortality in the world and results in about ten thousand deaths each year. Cirrhosis of the liver, due to its high prevalence and its debilitating and sometimes deadly complications, is one of the main problems in the country's health care system. The method of measuring free radicals was based on 1, 2-diphenyl Pykrya Hydrazyl (DPPH). This combination is based on reviving color from pink to pale yellow in the 520nm absorbance readings. In this study, the mean and standard deviation in sham + curcumin (166.11±10.12), compared with BDL + curcumin (86.53±13.93), are higher and the difference between the two groups is statistically significant (P <0.05). Key words: Free radicals, curcumin, cirrhotic, 1, 2-diphenyl Pykrya Hydrazyl\"","PeriodicalId":119340,"journal":{"name":"Journal of Biology and Today`s World","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125748766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-vitro Assessment of Probiotic Potential of Lactic acid Bacteria","authors":"Madiha Arslan, T. Shaheen, M. Siddiq, A. Nadeem, A. Hussain, Fakhar Hayyat, Junling Shi","doi":"10.15412/J.JBTW.01041001","DOIUrl":"https://doi.org/10.15412/J.JBTW.01041001","url":null,"abstract":"\"Lactic Acid Bacteria (LAB) are the major constituents of the human intestinal micro flora. These have been considered as the major microbial group having probiotic potential. They are able to exert a wide range of beneficial health promoting effects that include inhibition of pathogen growth and production of antimicrobials and vitamins. In food industry, LAB have received considerable attention due to their probiotic activities. The probiotic strain’s ability to resist unfavorable physiological conditions of the gastrointestinal tract (GIT) depends on various factors like tolerance to bile secretion and lysozyme resistance. The present study was conducted with the objectives of in-vitro screening of various indigenous LAB strains isolated from milk and yogurt in order to evaluate their probiotic potential. For probiotic potential, the pH sensitivity, bile resistance, H2O2 and lysozyme resistance of LAB strains will be determined. Our in-vitro studies concluded that PL5 ( Lactobacillus paracasei), PL8 (Enterococcus faecium), PL13 (L. delbrueckii) and PL14 (L. saekei) proved to be most promising LAB strains among all that exhibited a high resistance towards low pH, bile, lysozyme and H2O2. In future, these in-vitro studies will facilitate scientists to select suitable LAB strains and evaluate their probiotic properties in-vivo to understand how they affect human host and cope with adverse conditions in human GI tract. In future, more potential properties of these strains may be checked, like folate & oxalate production, adhesion to mucin, production of β- galactosidase, cholesterol reduction mechanisms on LAB strains. It will be helpful to design new protocols for in-depth studies related to their potentia\"","PeriodicalId":119340,"journal":{"name":"Journal of Biology and Today`s World","volume":"448 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115614515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro regeneration of watermelon seed segments","authors":"M. Ameri, M. Lahouti, A. Bagheri, A. Sharifi, F. K. Akhar","doi":"10.15412/J.JBTW.01040803","DOIUrl":"https://doi.org/10.15412/J.JBTW.01040803","url":null,"abstract":"\"Various parts of a seed have different responses to same culture condition, because of dissimilar hormone concentration and enzyme activity. Indirect regeneration of watermelon seed was tested with different parts: hypocotyl, basal, central, distal and peripheral zone (parts 1, 2, 3, 4 and 5, respectively). The different parts were cultured in MS medium containing 3.5 mg/l BA and 0.5 mg/l IAA. Photoperiod (16h light/8h dark) or dark condition were used as light treatment. Every 2 weeks the callogenesis and regeneration percentages and number of regenerated leaves were assessed until 6 weeks. Best callogenesis and regeneration percent observed in dark and light condition, respectively. A regular pattern of regeneration find in seed segments. The rate of regeneration was faster for second and third part of seed in compare to fourth and fifth parts (p<0.01). The peripheral parts show low density of regenerated plantlets. Regenerated branches were rooted in MS medium containing 0.1 mg/l IBA, and obtained plantlets with appropriate root system, were cultivated in hydroponic and sand pots to acclimatize. The best acclimatization (90 %) were gained in hydroponic culture\"","PeriodicalId":119340,"journal":{"name":"Journal of Biology and Today`s World","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124680645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation and Identification of Phosphate Solubilizing Bacteria from Pistachio Farms of Anar City","authors":"M. Zolfaghari, F. Kafilzadeh","doi":"10.15412/J.JBTW.01040503","DOIUrl":"https://doi.org/10.15412/J.JBTW.01040503","url":null,"abstract":"","PeriodicalId":119340,"journal":{"name":"Journal of Biology and Today`s World","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128063346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cholecalciferol for Primary Dysmenorrhea in a College- aged Population- A Clinical Trial","authors":"M. Ataee, M. Zangeneh, M.b Mahboubi","doi":"10.15412/J.JBTW.01040204","DOIUrl":"https://doi.org/10.15412/J.JBTW.01040204","url":null,"abstract":"\"Primary dysmenorrhea is the most common gynecological complaints among adolescents. The purpose of the present study is to evaluate the effect of vitamin-D in reduction of pelvic pain in women suffering primary dys-menorrhea. This double blind randomized clinical trial was performed on women suffering from primary dys-menorrhea. For case group (n=27), vitamin-D was prescribed as a single dose of 300 000IU starting 5 days be-fore the beginning of menstruation, for three consecutive cycles. For control group (n=27), a Placebo was pre-scribed. Pain severity was evaluated using Visual Analogue Scale (VAS). There was a reduction of the pain score in the first month for both groups (mean score of 5.3±2.24 for group-A and 5.21±2.35 for group-B). In the next two months pain reduction continued for group-A, but for group-B pain scores grows higher than the first month. In-dependent student t-test showed that pain score was significantly lower in group-A than group-B after beginning of therapy in the second and third month (P= 0.023 and 0.001 respectively).There was no significant difference between two groups in the level of vitamin-D in follicular and luteal Phase. Vitamin-D causes significant pain re-duction in primary dysmenorrhea that due to its safety can be a simple treatment for this problem.\"","PeriodicalId":119340,"journal":{"name":"Journal of Biology and Today`s World","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116436759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Biological Activity and Phenolic Compounds of Cardaria draba (L.) Extracts","authors":"J. Sharifi‐Rad, S. Hoseini-Alfatemi, M. Sharifi-Rad, J. Silva, M. Rokni, M. Sharifi-Rad","doi":"10.15412/J.JBTW.01040901","DOIUrl":"https://doi.org/10.15412/J.JBTW.01040901","url":null,"abstract":"\"The antibacterial, antioxidant, anti-inflammatory and scolicidal activities, as well as phenolic compounds from various leaf and seed extracts of Cardaria draba (L.) Desv. (whitetop) were examined. The antibacterial activity against two Grampositive bacteria (Staphylococcus aureus and Bacillus subtilis) and two Gram-negative bacteria (Pseudomonas aeruginosa and Escherichia coli) was evaluated by the agar well diffusion method. Antioxidant activity was assayed by using the seed and leaf extracts on synthetic DPPH free radicals and assessing their capacity to inhibit the peroxidation of linoleic acid. Anti-inflammatory activity was investigated by protein denaturation. The viability of Echinococcus granulosus protoscolices was investigated by evaluating their motility under a light microscope. Phenolic compounds in leaf and seed extracts were analyzed by HPLC. Our result showed that the MICs of various C. draba extracts against bacterial strains ranged from 3 to 134 μg/mL. The maximum and minimum MIC values for S. aureus were 3 μg/mL for the ethanolic leaf extract (ELE) and 86 μg/mL for the aqueous seed extract (ASE), respectively. Results of antioxidant assays showed that the ethanolic seed extract (ESE) had a significantly higher antioxidant capacity than ELE, and that both extracts had significantly lower antioxidant capacity than BHA and ascorbic acid. Results of the anti-inflammatory assay showed that as the concentration of extracts and control increased, there was a concomitant increase in the percentage inhibition of protein denaturation. ELE (500 μg/mL) and ESE (100 μg/mL) showed maximum and minimum percentage inhibition of protein denaturation (90% and 48%, respectively). Scolicidal activity and percentage mortality increased with exposure time, but the level depended on the extract concentration. In total, 16 compounds were identified from both extracts. Isorhamnetin (13.85%), quercetin (12.9%), and kaempferol (11.5%) were most abundant compounds in ELE, while the most abundant compounds in ESE were caffeic acid (13.3%), p-coumaric acid (7.9%), sinapic acid (7.9%), and ellagic acid (7.9%). These results support the therapeutic potential of C. draba.\"","PeriodicalId":119340,"journal":{"name":"Journal of Biology and Today`s World","volume":"482 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116690708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tumor Markers and Hepatocellular Carcinoma","authors":"M. Negahdary, A. Eftekhari, S. Mirzaei, Mojganalsadat Basirizadeh, S. Ghobadzadeh","doi":"10.15412/J.JBTW.01040601","DOIUrl":"https://doi.org/10.15412/J.JBTW.01040601","url":null,"abstract":"\"survival rate of patients. Measurement of Alfa-Fetoprotein (AFP) in combination with iconography and liver biopsy are commonly used in the diagnosis of liver cancer as well as HCC. Despite the wide use of AFP in HCC diagnosis and introducing this tumor marker as the gold standard biomarker for HCC detection, the specificity and sensitivity of AFP used in screening for HCC is very controversial. In recent years, along with development of molecular biology and extensive research about ethnology of cancers and simultaneously advances in technology, researchers identified new tumor markers in this disease. In the latest researches various biomarkers including embryonic antigen, protein antigens, cytokines, enzymes and isoenzymes and related genes for effective early diagnosis and monitoring of hepatocellular carcinoma are introduced. In this review, a summary of the data of various studies that discuss new tumor markers involved in hepatocellular carcinoma and classification of these biomarkers was investigated Recently, use of different nanoparticle metal oxides for preventing the spread of microorganisms has reached to the expanding field of nanomaterial research. The objective of this study is to validate combined ultrasound and CuO or MgO noparticle treatments for inactivating Staphylococcus aureus and Pseudomonas aeruginosa. Results showed that nanoparticles of different materials vary in their effectiveness. Ultrasound increased the antibacterial effect of CuO nanoparticles more than the increased antibacterial effect of MgO. These results indicated that CuO or MgO nanoparticles exhibited antibacterial properties that could be additionally enhanced in the presence of ultrasound and, thus, should be further studied for a wide range of medical device anti-infection applications.\"","PeriodicalId":119340,"journal":{"name":"Journal of Biology and Today`s World","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125231449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of Drug Abuse and Drug Dependence in Individuals Visiting Drug Abuse Treatment Centers in Kermanshah Province in 2013","authors":"M. Moradi, A. Aghaei, F. Najafi, M.b Mahboubi, M. Ataee, B. Lotfi, V. Farnia, Touraj Ahmadi-Jouybari","doi":"10.15412/J.JBTW.01040703","DOIUrl":"https://doi.org/10.15412/J.JBTW.01040703","url":null,"abstract":"\"Kermanshah province in 2013. This study was a cross-sectional study that was conducted on those visiting drug abuse treatment centers in Kermanshah province voluntarily during the year 2013. Using checklist, information was collected from the files of the individuals by trained experts and, if necessary, by asking individuals, physicians or the experts of the center. The analysis was performed using SPSS version16. Overall, 2652 patients’ information (in 80 centers) was studied. The mean age of individuals was 37.98 (±11.18) years and more than 97% of the individuals were male. Opium, tramadol and hashish were the most frequently used substances that were consumed for the first time by the individuals. The mean of years of use for traditional (natural) substances was much more than that for synthetic substances. Proportion of drug use did not differ between men and women. However, the proportion of synthetic materials and non-narcotic substances was significantly different. Based on the results it can be said that that drug abuse is more prevalent among young individuals, educated individuals and those with family history. Since the synthetic drug abuse is increasing, new strategies for prevention of access to these drugs and treatment should be a priority in the related programs.\"","PeriodicalId":119340,"journal":{"name":"Journal of Biology and Today`s World","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126487699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Socio-demographic Factors of Aggression among Medical College Students","authors":"M. Mirzaei-Alavijeh, Parastoo Hossini, Somayeh Hayati, A. Aghaei, B. Karami-Matin","doi":"10.15412/J.JBTW.01040801","DOIUrl":"https://doi.org/10.15412/J.JBTW.01040801","url":null,"abstract":"\"Aggressive behavior in college students can be considered as an analyst for crime, drug abuse, depression and academic failure. The aim of this study was to determine the prevalence of and the factors related with aggression among a sample of Kermanshah medical college students. In this cross-sectional, showed in Kermanshah University of Medical Sciences, in the western Iran, a total of 601 students were randomly selected to voluntarily participate in the study. Participants filled out a Buss-Perry aggression questionnaire. Data were analyzed by SPSS version 21 using logistic regression statistical tests at 95% significant level. Almost, 15.3% of the participants were aggressive. The mean score of aggression was 61.1 [95% CI: 59.6, 62.7], ranged from 29 to 140. Logistic regression showed that marital status and smoking were the most influential predictive factors on aggressive behaviour. Our findings showed a high level of aggressive behaviour among college students; it seems that a designing intervention to reduce aggressive behaviour and improve mental health program among college students is necessary.\"","PeriodicalId":119340,"journal":{"name":"Journal of Biology and Today`s World","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130136033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Vitro assessment of the Anti-viral effect of Curcumin longa on Herpes Simplex Virus Type 1","authors":"M. Fani, M. Motamedifar, Mansour Zamani Kordshouli","doi":"10.15412/J.JBTW.01040502","DOIUrl":"https://doi.org/10.15412/J.JBTW.01040502","url":null,"abstract":"Antiviral drug resistance has become more prevalent in recent years. Therefore, this research aimed to investigate the antiviral effect of the of hydroalcoholic extract of Curcumin longa against human herpes simplex virus type 1. In this study, Curcumin longa hydroalcoholic extract was provided by the clevenger system. Cytotoxicity of Curcumin longa was determined on the Vero cell line. The antiviral effect of extract was evaluated by plaque reduction assays. The mean number of herpes simplex plaques was lower in group that received Curcumin longa extract with concentration of 2 mg/mL compared to that of the control group. Moreover, In contrast, acyclovir prevented 94.4% of virus plaque formation at the concentration of 2500 µg/mL. So, the finding of the present study showed the significant inhibitory effect of the Curcumin longa hydroalcoholic extract on HSV-1 replication. Curcumin longa hydroalcoholic extract or preparation can be recommended as a pharmaceutical source for controlling HSV-1 related diseases. However, it is necessary to investigate in-vivo the potential side effect of Curcumin longa.","PeriodicalId":119340,"journal":{"name":"Journal of Biology and Today`s World","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130916190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}