C S Garcete Delvalle, M J De Nova García, M R Mourelle Martínez
{"title":"Exfoliation of primary dentition in children with Osteogenesis Imperfecta medicated with bisphosphonates.","authors":"C S Garcete Delvalle, M J De Nova García, M R Mourelle Martínez","doi":"10.23804/ejpd.2025.2078","DOIUrl":"10.23804/ejpd.2025.2078","url":null,"abstract":"<p><strong>Aim: </strong>To study root resorption of the primary dentition in children with osteogenesis imperfecta (OI) medicated with bisphosphonates (BPs) and compare the results with a control group of healthy patients.</p><p><strong>Methods: </strong>A cross-sectional study was conducted analysing 20 panoramic radiographs belonging to children with OI with a mean age of 8.18 (±1.60), who had received BPs in a period equal to or greater than 1 year, comparing them to a control group of 367 panoramic radiographs belonging to healthy children with a mean age of 9.19 (±1.62). Children with tooth agenesis, caries or bilateral restorative treatments in the lower arch were excluded. Root resorption of primary teeth was examined with the Haavikko method and with the PixelStick® software. To indicate the presence of dentinogenesis imperfecta (DI), the radiographic characteristic of DI such as obliteration of the pulp chambers, bulbous crowns, and very narrow root walls, were taken into account. The cumulative dose of BPs was obtained by mathematically calculating the total dosage received (mg)/weight (kg) and multiplying the relative potency of the medication. The Mann-Whitney U test was used for comparisons, and p < 0.05 indicated statistical significance.</p><p><strong>Conclusion: </strong>Not differences in root resorption was found between children with DI or without DI. BPs therapy was associated with delay in root resorption of the primary molars and delay in the exfoliation of primary dentition in children with OI. Delayed root resorption should be considered, particularly as it may increase the number of impacted teeth in children already suffering from dental disorders.</p>","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":" ","pages":"24-30"},"PeriodicalIF":2.2,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145803529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bottle-feeding and gastroesophageal reflux disease improvement after restrictive tethered oral tissues release.","authors":"P Hand, G Olivi, G Gioco, C Lajolo","doi":"10.23804/ejpd.2023.1817","DOIUrl":"10.23804/ejpd.2023.1817","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to determine the impact of laser surgical tongue-tie, lip-tie, buccal-tie release on bottle-feeding and gastroesophageal reflux disease (GERD) after functional assessment of tongue and lip movement in a prospective cohort study conducted from June 2019 to June 2020 in a private general dental practice.</p><p><strong>Methods: </strong>Preoperative, one-week and one-month postoperative surveys were completed, using the Revised Infant Gastroesophageal Reflux Questionnaire (I-GERQ-R). All study participants were bottle-feeding dyads (0-12 weeks of age) with untreated ankyloglossia and/or tethered maxillary/buccal frena.</p><p><strong>Results: </strong>The study had 40 bottle feeding infants enrolled. Posterior :tongue-tie was noted in 67.5% of this cohort. Statistically significant improvement in I-GERQ-R scores was reported between preoperative (16.6, SD: 6.1; min-max: 8-28), 1 week (14.1, SD: 4.2; min-max: 6-24) and 1 month I-GERQ-R total scores (9.1, SD: 4.5; min-max:3-27) (ANOVA test - P <.001).</p><p><strong>Conclusion: </strong>This study confirms the need for functional assessment of tongue and lip movement for this significantly affected cohort when surgical release is proposed. Laser surgical release (frenotomy) of tongue-tie, lip-tie, buccal-tie resulted in significant improvement in I-GERQ-R outcomes were found for cohorts of the classically recognised anterior tongue-tie and the less obvious (without functional assessment) and less diagnosed posterior tongue tie were found.</p>","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":" ","pages":"96-104"},"PeriodicalIF":2.2,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9628499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Protzenko, C A Viana de Araújo, S M de Carvalho Gonzalez, F Rolemberg Riba, T Protzenko, J Llerena Junior
{"title":"Contributing Factors for Angle's Class III Phenotype in Crouzon Syndrome.","authors":"M Protzenko, C A Viana de Araújo, S M de Carvalho Gonzalez, F Rolemberg Riba, T Protzenko, J Llerena Junior","doi":"10.23804/ejpd.2025.2207","DOIUrl":"10.23804/ejpd.2025.2207","url":null,"abstract":"<p><strong>Aim: </strong>Crouzon syndrome (CS) is a rare genetic condition characterised by craniofacial malformations due to mutations in the FGFR2 gene. This study aimed to evaluate the contributing factors for Angle's Class III malocclusion in patients with CS through cephalometric analysis. Six patients with confirmed CS diagnosis were included in the study. Cephalometric measurements were performed using CT scans and compared to established norms. Pathogenic variants in the FGFR2 gene were identified in all patients. Phenotypic and cephalometric characteristics were assessed in each patient. Results showed consistent craniofacial abnormalities, including midface retrusion, mandibular prognathism, and malocclusion. Cephalometric analysis revealed specific patterns indicating growth deficiency at the posterior base of the skull, maxillary retroposition, and an anterior accommodation of the mandibular condyles in the glenoid fossa. These findings provide valuable insights into the underlying factors contributing to Angle's Class III malocclusion in patients with Crouzon syndrome.</p>","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":" ","pages":"59-64"},"PeriodicalIF":2.2,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145238099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"X-linked hypophosphatemia in childhood: dental involvement, diagnosis, and treatment.","authors":"P Defabianis, N Bocca, R Ninivaggi","doi":"10.23804/ejpd.2025.2348","DOIUrl":"10.23804/ejpd.2025.2348","url":null,"abstract":"<p><strong>Aim: </strong>X-linked hypophosphatemia (XLH) is a rare genetic disorder that causes skeletal deformities, growth retardation and oral complications, being dental abscesses the most frequent reported problem. Patient management is often poor due to a lack of care pathways, particularly in pediatric settings, and this highlights the need for updated clinical protocols. This study emphasises the importance of the role of pediatric dentists in the early recognition of XLH and in the multidisciplinary management of these patients, including early diagnosis, personalised therapies, and prevention to improve oral health and overall well-being.</p><p><strong>Methods: </strong>A comprehensive search was conducted to identify studies focused on dental aspects in XLH pediatric patients published from 2020 and 2024. Databases such as the Cochrane Library and MEDLINE via PubMed databases were searched using terms and MeSH terms including X-linked hypophosphatemia, X-linked hypophosphatemic rickets, XLH, teeth, dental, child, oral health, and oral health-related quality of life. Only English-language articles were included.</p><p><strong>Conclusion: </strong>In the end the complexity and rarity of XLH often results in diagnostic delays, compromising either dental or general treatment. For these reasons, the need for early diagnosis and integrated care is evident; development of specific guidelines to improve outcomes and oral health-related quality of life in growing patients is strongly required.and nutritional disorders. The study emphasises the importance of including a dental evaluation in the follow-up of premature infants from the first months of life.</p>","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":" ","pages":"37-41"},"PeriodicalIF":2.2,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145803619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N T Snigdha, M I Karobari, A Kamarudin, N A Samsudin, F Baharin, N Dziaruddin, A A Assiry, A M Luke, G A Scardina
{"title":"A Systematic Review and Meta-analysis of Regenerative Pulpotomy in the Treatment of Vital Primary Teeth.","authors":"N T Snigdha, M I Karobari, A Kamarudin, N A Samsudin, F Baharin, N Dziaruddin, A A Assiry, A M Luke, G A Scardina","doi":"10.23804/ejpd.2024.1981","DOIUrl":"10.23804/ejpd.2024.1981","url":null,"abstract":"<p><strong>Aim: </strong>To assess the clinical and radiographic success rates of regenerative pulpotomy compared to devitalising or preservative pulpotomy in treating vital pulp exposure in primary teeth.</p><p><strong>Methods: </strong>Comprehensive search with PubMed/MEDLINE, Cochrane Library, Web of Science, Google Scholar and Open Grey databases was done and two reviewers extracted the data after assessing the studies for eligibility criteria. The Cochrane Collaboration Tool and Minors Checklist assessed the quality of the selected studies. A meta-analysis was performed using RevMan (P<0.05).</p><p><strong>Conclusion: </strong>Within the limitations of the study, it can be concluded that MTA seemed to be the better alternative to FC and FS, showing a lower risk of failure and can be recommended for pulpotomy in primary teeth. BD also demonstrated promising results as a pulpotomy medicament.</p>","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":" ","pages":"105-120"},"PeriodicalIF":2.2,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142282357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L Šimunović, B Špiljak, A Z Kovač, L Vranić, D Negovetic Vranic
{"title":"Bilateral root absence of permanent first molars: literature review and case report.","authors":"L Šimunović, B Špiljak, A Z Kovač, L Vranić, D Negovetic Vranic","doi":"10.23804/ejpd.2025.2333","DOIUrl":"10.23804/ejpd.2025.2333","url":null,"abstract":"<p><strong>Aim: </strong>This case report and literature review aim to elucidate the rare occurrence of bilateral root absence in permanent first molars, emphasizing its clinical implications, diagnostic challenges, management, and possible association with systemic conditions. A unique case involving a 13-year-old male diagnosed with atypical hemolytic uremic syndrome (aHUS) is presented to illustrate these points.</p><p><strong>Methods: </strong>A comprehensive review of existing literature was conducted to explore the etiology, diagnosis, and management strategies for root absence. In addition, the detailed case study of the patient with aHUS and root absence of all four permanent first molars complements the review, providing insights into systemic impacts on dental development.</p><p><strong>Conclusion: </strong>This report emphasizes the need for a multidisciplinary approach in diagnosing and managing dental anomalies associated with systemic diseases. Further research is recommended to understand the systemic influences on dental root development and improve patient outcomes.</p>","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":" ","pages":"31-36"},"PeriodicalIF":2.2,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145803538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E Boccalari, M Serafin, M Grandinetti, A Caprioglio
{"title":"Orthodontics meets otorhinolaryngology: a collaborative approach to otitis media prevention.","authors":"E Boccalari, M Serafin, M Grandinetti, A Caprioglio","doi":"10.23804/ejpd.2025.2413","DOIUrl":"10.23804/ejpd.2025.2413","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the role of orthodontic and craniofacial orthopaedic interventions in the prevention and management of otitis media with effusion (OME), focusing particularly on rapid maxillary expansion (RME) and its implications for Eustachian tube function.</p><p><strong>Methods: </strong>A comprehensive search was conducted in PubMed, Embase, and Web of Science using a structured combination of MeSH terms by two expert researchers from inception to December 2024. Randomised and non-randomised prospective studies involving pediatric patients (2-18 years) with chronic OME were included. The effectiveness of preventive measures was compared with alternative treatments or no interventions. Study quality was assessed using the ROBINS-I v2 tool.</p><p><strong>Conclusion: </strong>RME emerges as a promising preventive option for managing OME particularly in patients with orthodontic indications. By addressing structural contributors to Eustachian tube dysfunction, RME improves middle ear health and complements otolaryngological interventions. Integrating orthodontic and otolaryngological strategies represents an effective multidisciplinary approach to reducing OME incidence and recurrence. Further studies are needed to confirm the long-term stability and the generalisability of these observed benefits.</p>","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":" ","pages":"47-52"},"PeriodicalIF":2.2,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145307157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K Awad, S Butt, E A Field, D Finn, K Hunter, B P Rajlawat, C E McCarthy
{"title":"Paediatric Oral Lichen Planus.","authors":"K Awad, S Butt, E A Field, D Finn, K Hunter, B P Rajlawat, C E McCarthy","doi":"10.23804/ejpd.2025.2379","DOIUrl":"10.23804/ejpd.2025.2379","url":null,"abstract":"<p><strong>Background: </strong>Lichen Planus is a chronic, mucocutaneous disease that may affect the oral mucosa, skin, genital mucosa, nails, and scalp. It occurs more frequently in adults than in children. Ten cases of Oral Lichen Planus (OLP), diagnosed in children presenting to the Liverpool University Dental Hospital (UK) Oral Medicine department are presented. The case series includes four male and six female patients, ranging in age from 10 to 17 years at diagnosis. A clinical diagnosis alone was made in five patients and five patients underwent an incisional biopsy, which confirmed a histological diagnosis consistent with OLP. In one case, moderate dysplasia was diagnosed, on a background of OLP. Five patients presented with asymptomatic disease. In symptomatic cases, treatments included topical anesthetic mouthwash and topical steroid preparations. OLP is classified as an oral potentially malignant disorder and approximately 1% of patients develop oral cancer, however no cases of malignant transformation have been reported in children. None of our paediatric patients with OLP have developed oral cancer during a mean follow up time of 2 years. However, ongoing clinical monitoring is required so that malignant change can be detected at the earliest possible stage when treatment is most successful.</p>","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":" ","pages":"42-46"},"PeriodicalIF":2.2,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145430514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of the Neonatal/Natal Teeth in Children: A Retrospective Observational Study.","authors":"M Belevcikli, E Hazar Bodrumlu","doi":"10.23804/ejpd.2025.2434","DOIUrl":"10.23804/ejpd.2025.2434","url":null,"abstract":"<p><strong>Aim: </strong>It is rare for teeth to be visible in the mouth at birth or shortly after birth, whether they are additional teeth or primary teeth that have erupted early. If there is excessive mobility, the tooth must be extracted to avoid the risk of aspiration. The aim of this study was to evaluate the characteristics of these teeth and their effects on the developing dentition in children with natal/neonatal tooth extraction.</p><p><strong>Methods: </strong>Out of a total of 26 patients in the study, 22 were contacted by phone and 16 of them came for a follow-up visit. At the patients' follow-up appointments, the stage of dental development, amount of space and the presence of any dental anomalies were assessed.</p><p><strong>Conclusion: </strong>Knowing the characteristics of natal-neonatal teeth, their differential diagnosis, what should be considered in treatment options, and the problems that may arise after extraction of these teeth provides an advantage in the management of these teeth, which is a rare condition.</p>","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":" ","pages":"53-58"},"PeriodicalIF":2.2,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145291535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Breastfeeding and craniofacial development: orthodontic prevention beginning at birth.","authors":"L Paglia","doi":"10.23804/ejpd.2026.27.01.01","DOIUrl":"10.23804/ejpd.2026.27.01.01","url":null,"abstract":"<p><p>Breastfeeding is universally recognised as the nutritional gold standard for the neonate, with well-established benefits on immunological, metabolic, and relational levels. However, in light of the evidence accumulated over recent years, limiting its value to the nutritional dimension alone is reductive. Breastfeeding also represents a powerful functional modulator of craniofacial growth and, consequently, an early potential determinant of orthodontic health. Suckling at the breast activates a complex neuromuscular pattern involving the tongue, lips, mandible, and perioral musculature in a coordinated and physiological manner. This functional pattern, which is more demanding and dynamic than artificial feeding, generates mechanical stimuli that are essential for the modelling of the hard palate, transverse expansion of the maxilla, and the correct maxillo-mandibular balance. In accordance with the functional matrix principle, bone growth is not an autonomous process but responds to the functional stimuli of the soft tissues: breastfeeding constitutes, during the first months of life, one of the principal biological inputs capable of directing such development. Epidemiological evidence reinforces this biological rationale. The meta-analysis by Peres et al. [2015] documented a significant reduction in the risk of malocclusion in breastfed children compared to those fed formula. Likewise, Boronat-Catalá et al. [2017] identified a dose-response association between duration of breastfeeding and lower prevalence of occlusal anomalies in the primary and mixed dentitions. Subsequent observational studies confirmed a reduced risk of anterior open bite and posterior crossbite in subjects breastfed for longer periods. The data pertaining to duration are particularly noteworthy: the protective effect appears to be more pronounced the longer breastfeeding is maintained. This suggests that the window of the first months of life represents a critical period of craniofacial plasticity, during which functional stimuli may exert a lasting influence on morphological development. Major health institutions have progressively incorporated these findings into their recommendations. The American Academy of Pediatrics, in the 2022 policy statement [Meek and Noble], highlights the contribution of breastfeeding to oro-facial functional development. Similarly, the Ministry of Health recommends exclusive breastfeeding for the first six months and its continuation until two years of age or beyond, acknowledging its impact on harmonious child development. Within the dental and orthodontic fields, these data warrant reflection: breastfeeding can no longer be regarded as an \"external\" factor with respect to dentofacial prevention. On the contrary, it represents the first natural functional orthodontic intervention, capable of reducing the incidence of malocclusions and oro-facial dysfunctions through the early modulation of muscular and respiratory stimuli. Methodological ","PeriodicalId":11930,"journal":{"name":"European journal of paediatric dentistry","volume":"27 1","pages":"2-3"},"PeriodicalIF":3.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147347799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}