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European annals of allergy and clinical immunology最新文献

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Nasal challenge with ketorolac: utility and safety in clinical practice. 酮咯酸的鼻腔挑战：临床实践中的实用性和安全性。
IF 2.3
European annals of allergy and clinical immunology Pub Date : 2023-12-20 DOI: 10.23822/EurAnnACI.1764-1489.321
L De Las Vecillas, M Sanchez-Jareño, M Lluch-Bernal, S Quirce, J Domínguez-Ortega, V López-Carrasco, P Barranco
{"title":"Nasal challenge with ketorolac: utility and safety in clinical practice.","authors":"L De Las Vecillas, M Sanchez-Jareño, M Lluch-Bernal, S Quirce, J Domínguez-Ortega, V López-Carrasco, P Barranco","doi":"10.23822/EurAnnACI.1764-1489.321","DOIUrl":"https://doi.org/10.23822/EurAnnACI.1764-1489.321","url":null,"abstract":"","PeriodicalId":11890,"journal":{"name":"European annals of allergy and clinical immunology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138797915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delayed postoperative reactions to metamizole: a diagnostic challenge. 甲氰咪唑术后延迟反应：诊断难题。
IF 2.3
European annals of allergy and clinical immunology Pub Date : 2023-12-05 DOI: 10.23822/EurAnnACI.1764-1489.317
A Lopes, M Paulino, A Spínola Santos, E Pedro, M Branco Ferreira
{"title":"Delayed postoperative reactions to metamizole: a diagnostic challenge.","authors":"A Lopes, M Paulino, A Spínola Santos, E Pedro, M Branco Ferreira","doi":"10.23822/EurAnnACI.1764-1489.317","DOIUrl":"https://doi.org/10.23822/EurAnnACI.1764-1489.317","url":null,"abstract":"<p><strong>Summary: </strong><b>Background.</b> Metamizole, a non-steroidal anti-inflammatory drug from the pyrazolone group, is a frequent cause of immediate hypersensitivity reactions and, more rarely, of delayed drug hypersensitivity reactions. Due to its favorable pharmacokinetic characteristics, metamizole is widely used in the postoperative period for pain control. <b>Methods.</b> Retrospective study of patients referred for allergological study between January 2012 and June2022 for postoperative hypersensitivity reactions. Clinical and diagnostic data were collected through review of patients' medical records. Twenty patients with postoperative hypersensitivity reactions were referred, of which 10 presented delayed reactions. We analyzed the results of skin prick, intradermal and patch tests performed with an intravenous metamizole solution as well as provocation tests performed with metamizole and acetylsalicylic acid. Cross-reactivity to non-steroidal anti-inflammatory drugs was excluded by confirmation of clinical tolerance to non-steroidal anti-inflammatory drugs or by acetylsalicylic acid provocation test. <b>Results.</b> In 7 of the 10 patients a delayed reaction to metamizole was diagnosed. These reactions were characterized as maculopapular exanthema, occurring in multiple postoperative settings. Skin tests were negative, except in one patient with late mild erythema in the ipsilateral upper limb and no reaction at the site of intradermal injection. Delayed hypersensitivity was demonstrated by late positive metamizole provocation tests. <b>Conclusions.</b> This study demonstrated that for a correct diagnosis a high degree of suspicion about possible delayed hypersensitivity drug reactions to metamizole in the postoperative setting is needed. In the investigation, provocation test with metamizole was decisive for diagnostic confirmation.</p>","PeriodicalId":11890,"journal":{"name":"European annals of allergy and clinical immunology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138487065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Skin atrophy after skin tests with corticosteroids for the diagnosis of SARS-CoV-2 vaccine excipients hypersensitivity. 皮质类固醇皮肤试验诊断严重急性呼吸系统综合征冠状病毒2型疫苗赋形剂超敏反应后的皮肤萎缩。
IF 2.3
European annals of allergy and clinical immunology Pub Date : 2023-11-01 Epub Date: 2023-01-13 DOI: 10.23822/EurAnnACI.1764-1489.282
V Fabbri, V G R Ortolani, L Caron, L Bono, C P Ratti, E Iemoli
{"title":"Skin atrophy after skin tests with corticosteroids for the diagnosis of SARS-CoV-2 vaccine excipients hypersensitivity.","authors":"V Fabbri, V G R Ortolani, L Caron, L Bono, C P Ratti, E Iemoli","doi":"10.23822/EurAnnACI.1764-1489.282","DOIUrl":"10.23822/EurAnnACI.1764-1489.282","url":null,"abstract":"","PeriodicalId":11890,"journal":{"name":"European annals of allergy and clinical immunology","volume":" ","pages":"319-322"},"PeriodicalIF":2.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10561346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Profile of patients attending a pediatric allergic clinic during COVID-19 pandemic-related lockdown: how many children could have been approached with telemedicine? 新冠肺炎流行病相关封锁期间在儿科过敏诊所就诊的患者简介：有多少儿童可以接受远程医疗？
IF 2.3
European annals of allergy and clinical immunology Pub Date : 2023-11-01 Epub Date: 2023-07-18 DOI: 10.23822/EurAnnACI.1764-1489.305
A Ertugrul, E Ulusoy Severcan, H Arslan, I Bostancı
{"title":"Profile of patients attending a pediatric allergic clinic during COVID-19 pandemic-related lockdown: how many children could have been approached with telemedicine?","authors":"A Ertugrul, E Ulusoy Severcan, H Arslan, I Bostancı","doi":"10.23822/EurAnnACI.1764-1489.305","DOIUrl":"10.23822/EurAnnACI.1764-1489.305","url":null,"abstract":"","PeriodicalId":11890,"journal":{"name":"European annals of allergy and clinical immunology","volume":" ","pages":"310-312"},"PeriodicalIF":2.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9830562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic spontaneous urticaria: from the hunt for causes and pathogenesis to the identification of different endotypes. 慢性自发性荨麻疹：从寻找病因和发病机制到鉴定不同的内型。
IF 2.3
European annals of allergy and clinical immunology Pub Date : 2023-11-01 Epub Date: 2023-07-27 DOI: 10.23822/EurAnnACI.1764-1489.307
R Asero, A Tedeschi
{"title":"Chronic spontaneous urticaria: from the hunt for causes and pathogenesis to the identification of different endotypes.","authors":"R Asero, A Tedeschi","doi":"10.23822/EurAnnACI.1764-1489.307","DOIUrl":"10.23822/EurAnnACI.1764-1489.307","url":null,"abstract":"<p><strong>Summary: </strong>The hunt for the causes and pathogenic mechanisms involved in chronic spontaneous urticaria (CSU) has engaged clinicians and scientists for decades. Although not all aspects of the disease are defined, our knowledge has now improved to the point that we can consider CSU as an umbrella clinical phenotype under which several different endotypes probably exist. The present article will briefly summarize the fascinating history of the progress in our knowledge of this disease.</p>","PeriodicalId":11890,"journal":{"name":"European annals of allergy and clinical immunology","volume":" ","pages":"253-260"},"PeriodicalIF":2.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9876788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical severity of LTP syndrome is associated with an expanded IgE repertoire, FDEIA, FDHIH, and LTP mono reactivity. LTP综合征的临床严重程度与扩大的IgE库、FDEIA、FDHIH和LTP单反应性有关。
IF 2.3
European annals of allergy and clinical immunology Pub Date : 2023-09-15 DOI: 10.23822/EurAnnACI.1764-1489.314
E Scala, D Abeni, V Villella, D Villalta, L Cecchi, V Pravettoni, M Giani, E Caprini, R Asero
{"title":"Clinical severity of LTP syndrome is associated with an expanded IgE repertoire, FDEIA, FDHIH, and LTP mono reactivity.","authors":"E Scala,&nbsp;D Abeni,&nbsp;V Villella,&nbsp;D Villalta,&nbsp;L Cecchi,&nbsp;V Pravettoni,&nbsp;M Giani,&nbsp;E Caprini,&nbsp;R Asero","doi":"10.23822/EurAnnACI.1764-1489.314","DOIUrl":"https://doi.org/10.23822/EurAnnACI.1764-1489.314","url":null,"abstract":"<p><strong>Summary: </strong><b>Background.</b> LTP allergy is often a challenge for clinicians. We evaluated a multiplex diagnostic approach with diverse cofactors to stratify LTP syndrome risk. <b>Methods.</b> Of the 1,831 participants screened with 'Allergy Explorer-ALEX-2', 426 had reactions to at least one LTP. Data was gathered and recorded via an electronic database. <b>Results.</b> Reactivity to peach Pru p 3 was found in 77% of individuals with LTP allergy. Higher levels of specific IgE and concurrent sensitization to more than 5 molecules (50% of all LTP-sensitised participants, 62% of symptomatic cases) were significantly associated with an increased risk of severe reactions (p = 0.001). Several cofactors, either alone or in combination, also influenced patients' clinical outcomes. Some cofactors increased the risk of severe reactions, such as mono reactivity to LTP in 44.6% of cases (p = 0.001), FDEIA in 10.8% of patients (p = 0.001), and FDNIH in 11.5% (p = 0.005). On the other hand, reactivity to PR10 (24.2%; p = 0.001), profilin hypersensitivity (10.3%; p = 0.001), and/or atopic dermatitis (16.7%; p = 0.001) had a mitigating effect on symptom severity. <b>Conclusions.</b> Clinical severity of LTP syndrome is associated with an expanded IgE repertoire in terms of the number of LTP components recognized and increased IgE levels in individual molecules. Ara h 9, Cor a 8, and Mal d 3 showed the strongest association with clinical severity. In addition, several cofactors may either exacerbate (FDEIA, FDHIH, and LTP monoreactivity) or ameliorate (atopic dermatitis and co-sensitization to profilin and/or PR10) individual patient outcomes. These factors may be utilized for the daily clinical management of LTP syndrome.</p>","PeriodicalId":11890,"journal":{"name":"European annals of allergy and clinical immunology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10242276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypersensitivity to lipoic acid. 对硫辛酸过敏。
IF 2.3
European annals of allergy and clinical immunology Pub Date : 2023-09-06 DOI: 10.23822/EurAnnACI.1764-1489.310
F Marchi, A Carabelli
{"title":"Hypersensitivity to lipoic acid.","authors":"F Marchi,&nbsp;A Carabelli","doi":"10.23822/EurAnnACI.1764-1489.310","DOIUrl":"https://doi.org/10.23822/EurAnnACI.1764-1489.310","url":null,"abstract":"","PeriodicalId":11890,"journal":{"name":"European annals of allergy and clinical immunology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10516232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cost-effectiveness analysis of grass pollen specific immunotherapy in children with allergic rhinitis compared to the standard of care symptomatic treatment in Portugal. 草花粉特异性免疫疗法治疗儿童过敏性鼻炎的成本效益分析与葡萄牙标准护理症状治疗的比较。
IF 2.3
European annals of allergy and clinical immunology Pub Date : 2023-09-01 Epub Date: 2021-12-17 DOI: 10.23822/EurAnnACI.1764-1489.240
M Farraia, I Paciência, F Castro Mendes, J Cavaleiro Rufo, L Delgado, A Moreira
{"title":"Cost-effectiveness analysis of grass pollen specific immunotherapy in children with allergic rhinitis compared to the standard of care symptomatic treatment in Portugal.","authors":"M Farraia,&nbsp;I Paciência,&nbsp;F Castro Mendes,&nbsp;J Cavaleiro Rufo,&nbsp;L Delgado,&nbsp;A Moreira","doi":"10.23822/EurAnnACI.1764-1489.240","DOIUrl":"10.23822/EurAnnACI.1764-1489.240","url":null,"abstract":"<p><strong>Summary: </strong><b>Background.</b> Cost-effectiveness studies evaluating allergen immunotherapy (AIT) in children are scarce. We aim to compare the cost-effectiveness of subcutaneous (SCIT) and sublingual immunotherapy (SLIT) against standard-of-care (SOC) treatment in children with grass pollen allergic rhinitis. <b>Methods.</b> We created a Markov model to compare the three strategies over a 10-year horizon. SOC was the reference to calculate the incremental cost-effectiveness ratio (ICER). Deterministic and probabilistic sensitivity analysis were used to assess models' uncertainty. <b>Results.</b> We obtained an ICER of € 12,605 and € 6,318 for SLIT and SCIT, respectively. In sensitivity analysis, SCIT was more cost-effective than SLIT. <b>Conclusions.</b> AIT is cost-effective in children with grass pollen allergic rhinitis, especially for the subcutaneous route.</p>","PeriodicalId":11890,"journal":{"name":"European annals of allergy and clinical immunology","volume":"55 5","pages":"212-228"},"PeriodicalIF":2.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10212370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atopic dermatitis in adolescents with acne vulgaris. 青少年寻常痤疮的特应性皮炎。
IF 2.3
European annals of allergy and clinical immunology Pub Date : 2023-09-01 Epub Date: 2022-01-26 DOI: 10.23822/EurAnnACI.1764-1489.244
S Todo Bom Costa, C Tapadinhas, M L Sampaio
{"title":"Atopic dermatitis in adolescents with acne vulgaris.","authors":"S Todo Bom Costa,&nbsp;C Tapadinhas,&nbsp;M L Sampaio","doi":"10.23822/EurAnnACI.1764-1489.244","DOIUrl":"10.23822/EurAnnACI.1764-1489.244","url":null,"abstract":"Atopic dermatitis (AD) is a chronic skin disease characterized by severe pruritus, erythema, edema, crusting, excoriation, lichenification and skin dryness. AD is often diagnosed during childhood, though the onset of symptoms may occur at any time. Lesions in older children and adults are usually located in flexural areas along with the head and neck. Facial involvement is also common in AD, not only in children but additionally in adolescents [1]. This inflammatory disease is characterized by skin microbial dysbiosis and barrier dysfunction. Initial inflammation has a T2 profile in response to allergens, which is later amplified by skin barrier breaking and reduction of antimicrobial peptides. This promotes skin pathogens growth (mainly Staphylococcus aureus) and the evolution to a T2, T1 and T17 pattern [2, 3]. AD is often associated with other atopic diseases such as rhinitis and asthma.","PeriodicalId":11890,"journal":{"name":"European annals of allergy and clinical immunology","volume":"55 5","pages":"246-249"},"PeriodicalIF":2.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10147666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is polyethylene glycol allergy a real contraindication to COVID-19 mRNA vaccines? 聚乙二醇过敏是新冠肺炎mRNA疫苗的真正禁忌症吗？
IF 2.3
European annals of allergy and clinical immunology Pub Date : 2023-09-01 Epub Date: 2022-05-19 DOI: 10.23822/EurAnnACI.1764-1489.253
A Zancanaro, F RIzzo, R Dittadi
{"title":"Is polyethylene glycol allergy a real contraindication to COVID-19 mRNA vaccines?","authors":"A Zancanaro,&nbsp;F RIzzo,&nbsp;R Dittadi","doi":"10.23822/EurAnnACI.1764-1489.253","DOIUrl":"10.23822/EurAnnACI.1764-1489.253","url":null,"abstract":"","PeriodicalId":11890,"journal":{"name":"European annals of allergy and clinical immunology","volume":"55 5","pages":"243-245"},"PeriodicalIF":2.3,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10212391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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