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76eP Clinical-grade comprehensive genomic profiling (CGP) of urothelial carcinoma (UC) 尿路上皮癌（UC）的临床级综合基因组图谱（CGP）
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-09-01 DOI: 10.1016/j.esmoop.2025.105651
P. Bose , A. Gibson , M. Dean , T. Xu , M. Murali , M. Kolinsky , S.A. North , D.Y.C. Heng , J.D. Ruether , S. Karim , V. Navani , R. Lee-Ying , B. Osborne , T.A. Bismar , R. Fahidi , S. Sharma , S. Alam , F. Khan , N. Alimohamed , S.M. Yip
{"title":"76eP Clinical-grade comprehensive genomic profiling (CGP) of urothelial carcinoma (UC)","authors":"P. Bose , A. Gibson , M. Dean , T. Xu , M. Murali , M. Kolinsky , S.A. North , D.Y.C. Heng , J.D. Ruether , S. Karim , V. Navani , R. Lee-Ying , B. Osborne , T.A. Bismar , R. Fahidi , S. Sharma , S. Alam , F. Khan , N. Alimohamed , S.M. Yip","doi":"10.1016/j.esmoop.2025.105651","DOIUrl":"10.1016/j.esmoop.2025.105651","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 105651"},"PeriodicalIF":8.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145183486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
77eP Decoding glioblastoma through integrated analysis using the COSMIC knowledge base 通过COSMIC知识库的综合分析解码胶质母细胞瘤
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-09-01 DOI: 10.1016/j.esmoop.2025.105652
L. Chadelle, M. Starkey, R. Steele, M. Madhumita, H. Pedro, S. Jupe, J. Wilding, Z. Sondka, J. Teague
{"title":"77eP Decoding glioblastoma through integrated analysis using the COSMIC knowledge base","authors":"L. Chadelle, M. Starkey, R. Steele, M. Madhumita, H. Pedro, S. Jupe, J. Wilding, Z. Sondka, J. Teague","doi":"10.1016/j.esmoop.2025.105652","DOIUrl":"10.1016/j.esmoop.2025.105652","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 105652"},"PeriodicalIF":8.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145183487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
86P Molecular mechanisms of alcohol-driven HCC: PERK/ATF4/LAMP3 activation and its non-coding RNAs regulation 酒精驱动HCC的分子机制：PERK/ATF4/LAMP3激活及其非编码rna调控
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-09-01 DOI: 10.1016/j.esmoop.2025.105662
H. Goyal, J. Kaur
{"title":"86P Molecular mechanisms of alcohol-driven HCC: PERK/ATF4/LAMP3 activation and its non-coding RNAs regulation","authors":"H. Goyal, J. Kaur","doi":"10.1016/j.esmoop.2025.105662","DOIUrl":"10.1016/j.esmoop.2025.105662","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 105662"},"PeriodicalIF":8.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145183491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
46P Integrative meta-analysis and validation of gene expression of oral mucosal pre-malignant conditions to identify candidate genes in oral submucous fibrosis 口腔黏膜恶性前病变基因表达的综合meta分析和验证，以确定口腔黏膜下纤维化的候选基因
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-09-01 DOI: 10.1016/j.esmoop.2025.105622
S. Subramaniyan , Y. Madhavan , A. Premanand , V. Shyamsundar , M. Kuppuloganathan , S. Ravindran , R. Rajkumari , A. Krishnamurthy , D. Catakapatri Venugopal , V. Ramshankar
{"title":"46P Integrative meta-analysis and validation of gene expression of oral mucosal pre-malignant conditions to identify candidate genes in oral submucous fibrosis","authors":"S. Subramaniyan , Y. Madhavan , A. Premanand , V. Shyamsundar , M. Kuppuloganathan , S. Ravindran , R. Rajkumari , A. Krishnamurthy , D. Catakapatri Venugopal , V. Ramshankar","doi":"10.1016/j.esmoop.2025.105622","DOIUrl":"10.1016/j.esmoop.2025.105622","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 105622"},"PeriodicalIF":8.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145183458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
55P Proteomic profiling of advanced hepatocellular carcinoma identifies predictive signatures of response to treatments 晚期肝细胞癌的55P蛋白质组学分析确定了对治疗反应的预测特征
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-09-01 DOI: 10.1016/j.esmoop.2025.105630
F. Saltel , A. Delamarre , M. Decraecker , J.F. Blanc , S. Di Tommaso , C. Dourthe , J-W. Dupuy , I. Mahouche , N. Allain , J. Giraud , B. Pinson , P. Biolac-Sage , J. Boursier , B. Lebail , A-A. Raymond
{"title":"55P Proteomic profiling of advanced hepatocellular carcinoma identifies predictive signatures of response to treatments","authors":"F. Saltel , A. Delamarre , M. Decraecker , J.F. Blanc , S. Di Tommaso , C. Dourthe , J-W. Dupuy , I. Mahouche , N. Allain , J. Giraud , B. Pinson , P. Biolac-Sage , J. Boursier , B. Lebail , A-A. Raymond","doi":"10.1016/j.esmoop.2025.105630","DOIUrl":"10.1016/j.esmoop.2025.105630","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 105630"},"PeriodicalIF":8.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145183466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
59P PD-L1 overexpression on circulating tumor cells and CTC clusters: A potential biomarker across solid carcinomas 59P PD-L1在循环肿瘤细胞和CTC簇中的过表达：实体癌的潜在生物标志物
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-09-01 DOI: 10.1016/j.esmoop.2025.105634
J. Bajpai , N.S. Ghadyalpatil , A. Ramesh , S. Jayant , A. Bharde , K.R. Domadia , G.R. Aland , A. Vasudevan , G. Shafi , J. Khandare , R. Thirumalairaj
{"title":"59P PD-L1 overexpression on circulating tumor cells and CTC clusters: A potential biomarker across solid carcinomas","authors":"J. Bajpai , N.S. Ghadyalpatil , A. Ramesh , S. Jayant , A. Bharde , K.R. Domadia , G.R. Aland , A. Vasudevan , G. Shafi , J. Khandare , R. Thirumalairaj","doi":"10.1016/j.esmoop.2025.105634","DOIUrl":"10.1016/j.esmoop.2025.105634","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 105634"},"PeriodicalIF":8.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145183470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
63P Prognostic impact of systemic inflammation scores and KRAS mutation in colorectal cancer (CRC): A real-world cohort from northern Portugal 结直肠癌（CRC）的全身性炎症评分和KRAS突变的预后影响：来自葡萄牙北部的现实世界队列
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-09-01 DOI: 10.1016/j.esmoop.2025.105638
M.A.R. Falcão , G.R. Magalhães , H.M. Marta Nuñez , P.J.T.D. Castro , M.B. Gonçalves , N.B. Mourão , P.M. Araújo , M.S. Rocha , M. Sousa
{"title":"63P Prognostic impact of systemic inflammation scores and KRAS mutation in colorectal cancer (CRC): A real-world cohort from northern Portugal","authors":"M.A.R. Falcão , G.R. Magalhães , H.M. Marta Nuñez , P.J.T.D. Castro , M.B. Gonçalves , N.B. Mourão , P.M. Araújo , M.S. Rocha , M. Sousa","doi":"10.1016/j.esmoop.2025.105638","DOIUrl":"10.1016/j.esmoop.2025.105638","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 105638"},"PeriodicalIF":8.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145183474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
71eP Clinicomorphological features of gPALB2-associated breast cancer: Real-world single-institution experience of NGS testing in Russia gpalb2相关乳腺癌的临床形态学特征：俄罗斯NGS检测的真实单机构经验
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-09-01 DOI: 10.1016/j.esmoop.2025.105646
A. Stroganova , V. Fedko , V. Mileyko , T. Lisitsa , A. Kavun , A. Lebedeva , I. Prokopev , E.I. Kovalenko , E. Artamonova
{"title":"71eP Clinicomorphological features of gPALB2-associated breast cancer: Real-world single-institution experience of NGS testing in Russia","authors":"A. Stroganova , V. Fedko , V. Mileyko , T. Lisitsa , A. Kavun , A. Lebedeva , I. Prokopev , E.I. Kovalenko , E. Artamonova","doi":"10.1016/j.esmoop.2025.105646","DOIUrl":"10.1016/j.esmoop.2025.105646","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 105646"},"PeriodicalIF":8.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145183481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
73eP Prevalence and clinical implications of TP53 mutations in ovarian cancer: A next-generation sequencing analysis 卵巢癌中TP53突变的73eP患病率和临床意义：新一代测序分析
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-09-01 DOI: 10.1016/j.esmoop.2025.105648
E. Makharashvili , N. Otkhozoria
{"title":"73eP Prevalence and clinical implications of TP53 mutations in ovarian cancer: A next-generation sequencing analysis","authors":"E. Makharashvili , N. Otkhozoria","doi":"10.1016/j.esmoop.2025.105648","DOIUrl":"10.1016/j.esmoop.2025.105648","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 105648"},"PeriodicalIF":8.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145183483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
11P Profiling of PD-L1 and HER2 overexpression on cancer cells using AI-based macro-driven automation 使用基于人工智能的宏驱动自动化分析PD-L1和HER2在癌细胞中的过表达
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-09-01 DOI: 10.1016/j.esmoop.2025.105588
B. Bhosale , R. Gupta , V. Khobragade , M. Shinkre , N. Tandale , H. Shah , Y. Patil , P. Parmar , H. Bathani , R. Dave , G. Khutale , G.R. Aland , S. Jayant , J. Khandare , V. Jadhav
{"title":"11P Profiling of PD-L1 and HER2 overexpression on cancer cells using AI-based macro-driven automation","authors":"B. Bhosale , R. Gupta , V. Khobragade , M. Shinkre , N. Tandale , H. Shah , Y. Patil , P. Parmar , H. Bathani , R. Dave , G. Khutale , G.R. Aland , S. Jayant , J. Khandare , V. Jadhav","doi":"10.1016/j.esmoop.2025.105588","DOIUrl":"10.1016/j.esmoop.2025.105588","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 105588"},"PeriodicalIF":8.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145183528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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