{"title":"Treatment Outcomes and Prognostic Factors of Direct Pulp Capping in Permanent Teeth: A Systematic Review and Meta-Analysis.","authors":"Nattawut Prasertsuksom, Sittichoke Osiri, Nadasinee Jaruchotiratanasakul, Lalida Ongchavalit","doi":"10.14744/eej.2024.93723","DOIUrl":"https://doi.org/10.14744/eej.2024.93723","url":null,"abstract":"<p><strong>Objective: </strong>The objectives of this study were (i) to assess the overall treatment outcomes of direct pulp capping in permanent teeth and (ii) to investigate and identify the prognostic factors.</p><p><strong>Methods: </strong>For the selection of included studies, MEDLINE via Ovid, EMBASE, PubMed, Cochrane Library, and manual search methods were used. After thorough screening, the quality assessment and data extraction criteria were established.</p><p><strong>Results: </strong>This systematic review is comprised of 33 studies, including 11 prospective cohort studies, 9 retrospective cohort studies, and 13 randomized clinical trials. After applying the quality assessment criteria, 26 articles were included in the meta-analysis. The weighted pooled success rate was 83% with a 95% confidence interval between 79-87%. Meta-regression analysis indicated that rubber dam isolation in all treatment steps was significantly more effective than other techniques (risk ratio=1.44; 95% confidence interval 1.06-2.16, p<0.05).</p><p><strong>Conclusion: </strong>This study provides evidence of successful treatment outcomes using direct pulp capping in permanent teeth, with 'adequate tooth isolation\" identified as a significant prognostic factor.</p>","PeriodicalId":11860,"journal":{"name":"European Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142616639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Increasing the Apical Sizes of Root Enlarged for Root Canal Obturation Influences the Outcome of Single-Root-Canal Teeth Affected by Apical Periodontitis.","authors":"Shizu Hirata-Tsuchiya, Daisuke Furutama, Noriko Saito-Nakayama, Tomoya Naruse, Tomoki Kawayanagi, Saki Nishihama, Ayaka Miyata, Satomi Shirawachi, Naoki Sadaoka, Chutian Wang, Kazuma Yoshida, Jun Nakanishi, Shinji Matsuda, Katsuhiro Takeda, Hideki Shiba","doi":"10.14744/eej.2023.04274","DOIUrl":"10.14744/eej.2023.04274","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effect of increasing the apical size of roots enlarged for root canal obturation on the outcome of non-surgical endodontic treatment for teeth with apical periodontitis.</p><p><strong>Methods: </strong>In this retrospective study, we included 210 cases of single-rooted canals treated at our dental units between October 2009 and January 2022. The clinical outcomes of teeth with enlarged root apical size from the International Organization for Standardization standard numbers 25 to 100 were investigated.</p><p><strong>Results: </strong>The number of teeth with a root apical size of ≤50 and ≥ 55 were 158 and 52, respectively. In the former case, 144 (68.6%) teeth had good prognoses and 14 (6.7%) had poor prognoses. In the latter case, 28 (13.3%) teeth had good prognoses and 24 (11.4%) had poor prognoses.</p><p><strong>Conclusion: </strong>Unfavourable clinical outcomes were observed in root canal-filled teeth with an enlarged apical root size of ≥ 55. Thus, these sizes potentially indicate poor outcomes of nonsurgical endodontic treatments.</p>","PeriodicalId":11860,"journal":{"name":"European Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amatallah Hussein Al-Rawhani, Salsabyl Mohamed Ibrahim, Fatma M Abu Naeem
{"title":"Regenerative Treatment of Mature Teeth with Pulp Necrosis and Apical Periodontitis Using Biodentine Compared with MTA: Randomized Controlled Clinical Trial.","authors":"Amatallah Hussein Al-Rawhani, Salsabyl Mohamed Ibrahim, Fatma M Abu Naeem","doi":"10.14744/eej.2024.30075","DOIUrl":"https://doi.org/10.14744/eej.2024.30075","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this randomized, controlled study was to evaluate the effectiveness of Biodentine compared with MTA used as a pulp space barrier in healing periapical lesions and regaining pulp sensitivity after regenerative treatment in mature single-canal permanent teeth with pulp necrosis and apical periodontitis.</p><p><strong>Methods: </strong>The study involved 36 patients with mature teeth with necrotic pulp and apical periodontitis. The patient underwent a regenerative treatment that utilized the blood clot technique. Teeth were randomly allocated to either the intervention, Biodentine, group (n=18) or the control, MTA, group (n=18). The healing of periapical lesions and tooth sensibility were evaluated throughout follow-up visits for up to 18 months.</p><p><strong>Results: </strong>The study analyzed 31 patients; two patients within the biodentine group and three in the MTA group were lost to follow-up. After 18 months, both groups showed effective healing of periradicular lesions; 21 out of 31 patients (67.7%) were healed, ten patients (32.3%) were healing, and no failure cases occurred. There were no significant differences between the groups (p=1.00). More than 70% (22 out of 31 patients) regained their sensibility in their teeth, and the groups had no statistically significant difference (p=0.703).</p><p><strong>Conclusion: </strong>Regenerative treatment using blood clots with either MTA or Biodentine effectively resolved periapical lesions and regained the sensibility of mature teeth.</p>","PeriodicalId":11860,"journal":{"name":"European Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Camila Soares Lopes, Fernanda Ferrari Esteves Torres, Gisele Faria, Estela Sasso-Cerri, Juliane Maria Guerreiro-Tanomaru, Mario Tanomaru-Filho, Paulo Sérgio Cerri
{"title":"Calcium silicate-based intracanal medication: Physicochemical properties and effectiveness of techniques for removing medication from the human root canal.","authors":"Camila Soares Lopes, Fernanda Ferrari Esteves Torres, Gisele Faria, Estela Sasso-Cerri, Juliane Maria Guerreiro-Tanomaru, Mario Tanomaru-Filho, Paulo Sérgio Cerri","doi":"10.14744/eej.2024.35219","DOIUrl":"https://doi.org/10.14744/eej.2024.35219","url":null,"abstract":"<p><strong>Objective: </strong>Our purpose was to investigate the physicochemical properties of Bio-C Temp, a bioceramic intracanal medication, and whether its residues remain adhered to the dentine walls after conventional manual irrigation (CMI) or passive ultrasonic irrigation (PUI) in comparison to Calen.</p><p><strong>Methods: </strong>The pH after 12 hours, 1 day, 3 days, 7 days, 14 days, 21 days and 28 days, and the flow, radiopacity, and the solubility of the medications after immersion for 7 and 30 days in distilled water (dH2O) or phosphate-buffered saline (PBS) solution were evaluated. Filling capacity, and volumetric changes after 14 days were assessed by micro-computed tomography (micro-CT). The residues of medications after CMI or PUI were analysed with scanning electron microscopy. Statistical analysis was performed using ANOVA and Tukey's post-hoc test, Student's t test or the Kruskal-Wallis and Dunn post-hoc test (α = 0.05).</p><p><strong>Results: </strong>Bio-C Temp presented a lower pH, flow, volumetric change, and weight loss after immersion in PBS on the 7th and 14th days (p < 0.05) and greater radiopacity and filling capacity (p < 0.05) than Calen. Both medications showed lower solubility in PBS than in dH2O (p < 0.05). There was no difference in the residue content of the two medications between two irrigation methods in three-thirds of the roots (p > 0.05).</p><p><strong>Conclusion: </strong>Although Bio-C Temp had less volumetric loss and satisfactory filling capacity, this medication provided lower alkalinity than did Calen. Furthermore, neither CMI nor PUI completely removed the medicament residues within the human root canal.</p>","PeriodicalId":11860,"journal":{"name":"European Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142460946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arash Izadi, Faezeh Golmakani, Ezatolah Kazeminejad, Amin Mahdavi Asl
{"title":"Accuracy of Working Length Measurement Using Cone Beam Computed Tomography at Three Field of View Settings, Conventional Radiography, and Electronic Apex Locator: An Ex-vivo Study.","authors":"Arash Izadi, Faezeh Golmakani, Ezatolah Kazeminejad, Amin Mahdavi Asl","doi":"10.14744/eej.2023.97769","DOIUrl":"10.14744/eej.2023.97769","url":null,"abstract":"<p><strong>Objectives: </strong>Determining the working length (WL) in root canal treatment facilitates the treatment prognosis. The introduction of apex locators and new CBCT devices in dentistry influenced this consideration. This comparative study evaluated the accuracy of working length measurement by cone-beam computed tomography (CBCT) in three fields of view (FOVs), conventional radiography, and the apex locator Raypex 5.</p><p><strong>Methodology: </strong>The descriptive-analytical study was performed on 40 lower premolar teeth that met the inclusion criteria. Direct observation under the microscope was considered the gold standard and compared with measurements by the electronic apex locator, CBCT, and periapical images.</p><p><strong>Results: </strong>The results were analyzed by paired t-tests and Wilcoxon tests. A significance level of 0.05 was considered in this study. CBCT 5×5 FOV with a p-value of 0.733 and analog radiography with a p-value of 0.001 achieved the working lengths with the highest and lowest accuracy, respectively. In addition, the difference between actual and measured working length using analog radiography was significant (p-value <0.05).</p><p><strong>Conclusions: </strong>According to the results of this study, CBCT images at different FOVs and those taken by the apex locator Raypex 5 can be used as a reliable method for estimating the working length. (EEJ-2023-10-141).</p>","PeriodicalId":11860,"journal":{"name":"European Endodontic Journal","volume":" ","pages":"266-272"},"PeriodicalIF":1.6,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11413608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141893157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hayat Alghutaimel, Manal Matoug-Elwerfelli, Venkateshbabu Nagendrababu, Paul Michael Howell Dummer
{"title":"Endodontic Applications of Propolis in Primary and Permanent Teeth: A Scoping Review of Clinical Studies.","authors":"Hayat Alghutaimel, Manal Matoug-Elwerfelli, Venkateshbabu Nagendrababu, Paul Michael Howell Dummer","doi":"10.14744/eej.2024.65487","DOIUrl":"10.14744/eej.2024.65487","url":null,"abstract":"<p><strong>Objective: </strong>The use of propolis-based materials within endodontics to promote pulp wound healing or disinfect the root canal system has been a recent focus of scientists and clinicians. This is mainly because of the well-documented antimicrobial, anti-inflammatory, immunomodulatory and wound healing properties of propolis. This scoping review critically appraises the literature on the clinical applications of propolis-based compounds during endodontic therapy of primary and permanent teeth.</p><p><strong>Methods: </strong>An electronic literature search was performed in Scopus, PubMed, and Web of Science up to and including October 2023 to identify studies assessing the use of propolis during endodontic therapy of primary and permanent teeth. A combination of relevant MeSh terms and keywords was used. Only human clinical studies written in English were included. The identified manuscripts were screened and assessed for inclusion by two independent authors. Eligible manuscripts were then subjected to critical appraisal and data extraction with the information being summarised according to their clinical application.</p><p><strong>Results: </strong>A total of 26 human clinical studies were identified and included in the analysis. Propolis was investigated for use in the primary and permanent dentitions as a direct pulp capping or pulpotomy material as well as in root canal disinfection and root filling of teeth with non-vital pulps. Overall, the studies reported that the use of propolis was associated with promising outcomes in terms of efficacy to control inflammation, enhance tissue repair, and disinfection of the root canal system. However, a critical appraisal of the studies revealed a range of methodological and reporting deficiencies, resulting in unreliable results and conclusions in terms of the clinical outcomes reported.</p><p><strong>Conclusion: </strong>Although the studies on the use of propolis-based materials in endodontics reported promising clinical outcomes, they had a range of methodological and reporting flaws. Further well-designed and properly reported controlled clinical studies are essential to derive sound evidence-based conclusions on propolis-based materials. Furthermore, guidelines for quality assurance and safe use of propolis-based materials are necessary to enhance their production for commercial use in endodontics.</p>","PeriodicalId":11860,"journal":{"name":"European Endodontic Journal","volume":" ","pages":"167-79"},"PeriodicalIF":1.6,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11413607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140956896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noor Hayder Fadhil, Ahmed Hamid Ali, Raghad Abdulrazzaq Al Hashimi, Omar Sabri Al-Qathi, Federico Foschi
{"title":"Assessment of Treatment Quality Risk Factors Influencing the Radiographic Detection of Apical Periodontitis in Root-Filled Teeth: A Retrospective CBCT Analysis.","authors":"Noor Hayder Fadhil, Ahmed Hamid Ali, Raghad Abdulrazzaq Al Hashimi, Omar Sabri Al-Qathi, Federico Foschi","doi":"10.14744/eej.2024.03371","DOIUrl":"10.14744/eej.2024.03371","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to assess the treatment quality factors associated with the risk of radiographic detection of apical periodontitis (AP) in root-filled teeth (RFT) on CBCT images.</p><p><strong>Methods: </strong>Two hundred eighty-five CBCT scans of patients (range 18-60, mean 35.1) years old were selected from a pool of CBCT scans which were taken from 2016-2022. Gender and age were recorded. The presence/absence of AP, unfilled canal, perforation, zipping and ledge and homogenous/nonhomogeneous root canal filling (RCF), adequate/inadequate coronal restoration and under/over filled RCF and those within 0-2 mm from the radiographic apex were recorded for RFTs. Kappa was used to assess intra-consensus reliability. Chi-square and Binary logistic regression were used to assess and predict risk factors related to the detection of AP. A significant difference was set at p<0.05.</p><p><strong>Results: </strong>AP was present in 81.5% of RFTs. No significant difference was present in the AP prevalence in RFT between males and females, maxilla and mandible, right and left sides, RFT with adequate and inadequate coronal restoration and RFT with/without zipping and ledge and between RFT with overfilled and those with RCF end within 0-2 mm from the radiographic apex (p>0.05), respectively. Significantly higher AP prevalence was present in RFT with unfilled canal, perforations, non-homogenous and underfilled RCF (p<0.05), respectively. The odds of AP detection were 2.02, 5.5, 2 and 1.98 times higher in RFT with unfilled canal, perforations, non-homogenous and underfilled RCF, respectively. Intra-consensus reliability was (0.98, 0.95, 0.85, 0.81, 0.88, 0.85 and 0.92) for AP, unfilled canal, perforation, zipping and ledge, homogeneity of RCF, coronal restoration and length of RCF, respectively.</p><p><strong>Conclusion: </strong>The vast majority of teeth with previous root fillings presented with AP. AP detection risk was significantly higher in root-filled teeth with perforation, non-homogeneous, and underfilled root canal filling. Other factors do not influence the radiographic detection of AP in CBCT images. (EEJ-2024-02-042).</p>","PeriodicalId":11860,"journal":{"name":"European Endodontic Journal","volume":" ","pages":"252-259"},"PeriodicalIF":1.6,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11413595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141893158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Helder Fernandes de Oliveira, Luan Carlos Gomes Teixeira, Ismael Fernandes Da Silva Júnior, Francisco Ferreira Da Cruz, Hellen Cristina Silva, Alex Da Rocha Gonçalves, Daniel De Almeida Decurcio, Orlando Aguirre Guedes
{"title":"Effect of Disinfection Protocols on Bacterial Reduction in Mandibular Molars.","authors":"Helder Fernandes de Oliveira, Luan Carlos Gomes Teixeira, Ismael Fernandes Da Silva Júnior, Francisco Ferreira Da Cruz, Hellen Cristina Silva, Alex Da Rocha Gonçalves, Daniel De Almeida Decurcio, Orlando Aguirre Guedes","doi":"10.14744/hnhj.2024.47450","DOIUrl":"10.14744/hnhj.2024.47450","url":null,"abstract":"<p><strong>Objective: </strong>Evaluate the bacterial reduction effect of disinfection protocols used in lower molars infected by Enterococcus faecalis.</p><p><strong>Methods: </strong>Eighty extracted lower molars were prepared and inoculated with E. faecalis for 2 months. The teeth were then distributed into 2 control groups (n = 4) and 4 experimental groups (n = 18) in function of the disinfection protocol utilized: G1. WaveOne Gold (WOG), passive ultrasonic irrigation (PUI) and Ultracal; G2. WOG, PUI and calcium hydroxide (CH); G3. WOG, XP-Endo Finisher (XPF) and Ultracal; G4. WOG, XPF and CH. Bacteriological samples were collected previously (S1), after preparation (S2), final agitation (S3) and intracanal dressing (S4). Microbial growth was assessed according to culture turbidity and UV spectrophotometry. Statistical analyses used the Friedman test for paired samples and Kruskal-Wallis test for non-paired data (p<0.05).</p><p><strong>Results: </strong>No protocol eliminated E. faecalis effectively. The S2, S3 and S4 samples were statistically different from the S1 samples in G1, G2, G3 and G4 (p<0.05). Statistical differences were observed in bacterial reduction between G1 and G2 and G1 and G3 after the intracanal medicament (S4) (p<0.05).</p><p><strong>Conclusion: </strong>The WOG + PUI + CH disinfection protocol showed higher percentages of bacterial reduction.</p>","PeriodicalId":11860,"journal":{"name":"European Endodontic Journal","volume":" ","pages":"236-242"},"PeriodicalIF":1.6,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11413596/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141456044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luis F Jiménez-Rojas, Liliana P Artaza, Vanessa P Pessotti, Débora P Sellera, Jorge C Alberdi, Alessandra Baasch, Karen Brisson-Suárez, Flávio R F Alves, Isabela N Rôças, José F Siqueira
{"title":"Negotiating and Treating Lateral Canals: Report of 7 Cases.","authors":"Luis F Jiménez-Rojas, Liliana P Artaza, Vanessa P Pessotti, Débora P Sellera, Jorge C Alberdi, Alessandra Baasch, Karen Brisson-Suárez, Flávio R F Alves, Isabela N Rôças, José F Siqueira","doi":"10.14744/eej.2023.43265","DOIUrl":"10.14744/eej.2023.43265","url":null,"abstract":"<p><p>This is a series of 7 cases in which the operator penetrated lateral canals with instruments. Two teeth presented with irreversible pulpitis, 4 with necrotic pulps, and 1 with previous treatment. Except for the teeth with pulpitis, all the others were associated with apical periodontitis. The main root canal was always relatively straight, with the lateral canals at the middle third of the root. Suggestive images of lateral canal presence were seen on periapical radiographs in five cases. The clinician introduced intentionally small hand instruments in the lateral canal in 5 cases, while the penetration was fortuitous in the others. The lateral canals were obturated in all cases. Follow-up examination was possible in five cases, all of them showed evidence of successful clinical and radiographic outcomes. Introducing files into lateral canals may permit some preparation and penetration of irrigant solution, favoring disinfection and, consequently, enhancing the treatment outcome. (EEJ-2023-05-063).</p>","PeriodicalId":11860,"journal":{"name":"European Endodontic Journal","volume":" ","pages":"287-294"},"PeriodicalIF":1.6,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11413609/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141893159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Normal Saline or Sodium Hypochlorite Irrigation for Vital Pulp Therapy? A Non-Inferiority Randomized Controlled Trial.","authors":"Hataichanok Machareonsap, Papimon Chompu-Inwai, Nattakan Chaipattanawan, Chanika Manmontri, Areerat Nirunsittirat, Phichayut Phinyo","doi":"10.14744/eej.2023.30932","DOIUrl":"10.14744/eej.2023.30932","url":null,"abstract":"<p><p>criteria were randomized to each irrigant, 65 in the NaOCl and 60 in the NSS groups. ProRoot® MTA was used as a pulp dressing material in both groups and teeth were followed for 12 months. The primary outcome was the success of VPT; requiring both clinical and radiographic success to be considered as success. The hypothesis was that the absolute difference of VPT success in the NSS group was not worse than that in the NaOCl group, by a margin of 5%. The secondary outcome was discoloration; percentages of discolorations between both groups were compared. Results: Using a per protocol analysis, the absolute difference of VPT success between the NSS and NaOCl groups was 2.08% (95% CI: -1.95, 6.1). Perceptible gray discolorations were 80% and 63% in NaOCl and NSS groups (difference -17%; 95% CI: -40.0, 6.2; p=0.15). Conclusions: For MTA-VPT procedure, irrigation with NSS was not worse than that with NaOCl. However, both irrigants caused discoloration. (EEJ-2023-05-065).</p>","PeriodicalId":11860,"journal":{"name":"European Endodontic Journal","volume":" ","pages":"180-190"},"PeriodicalIF":1.6,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11413600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141906250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}