Equine Veterinary Journal最新文献

{"title":"Desmitis of the palmar or plantar ligaments of the proximal interphalangeal joint: A descriptive case series.","authors":"Manon W J Peeters, Stephan Ott, Elisabeth van Veggel, Dagmar Berner, Melanie Perrier","doi":"10.1111/evj.14547","DOIUrl":"https://doi.org/10.1111/evj.14547","url":null,"abstract":"<p><strong>Background: </strong>Limited reports in the literature are available regarding desmitis of the palmar/plantar ligaments of the proximal interphalangeal joint (PL-PIPJ); the clinical significance of such injuries is unknown.</p><p><strong>Objectives: </strong>To describe the ability to differentiate the PL-PIPJ on low-field magnetic resonance (MR) examination. To describe the injury characteristics of the PL-PIPJ on MR examination and the correlation with clinical features and lameness.</p><p><strong>Study design: </strong>Retrospective case series.</p><p><strong>Methods: </strong>Data and MR images of 29 horses were collected from the databases of three institutions. Horses were included when desmitis of the PL-PIPJ was present, specifically the axial palmar/plantar ligament, the abaxial palmar/plantar ligament, the proximal enthesis of the distal digital annular ligament, and the distal enthesis of the proximal digital annular ligament. The clinical features and lameness scores were noted for all cases. The MR examinations were reviewed. Ligaments were graded for visibility and degree of pathology by a board-certified diagnostic imaging specialist.</p><p><strong>Results: </strong>Differentiation between the different ligaments is not always reliably possible, especially as the abaxial palmar/plantar ligament was only distinctly visible in 4 out of 80 ligaments (5%, 95% confidence interval (CI): 1%-12%). Desmitis of the PL-PIPJ was the main MR finding in 13 out of 29 (45%, CI: 26%-64%) clinical cases. Periligamentous oedema was evident in 53 of the 71 (74%, CI: 63%-84%) abaxially located ligaments with desmitis. Enthesophyte formation was present in 34 out of 102 ligaments with desmitis (33%, CI: 24%-43%).</p><p><strong>Main limitations: </strong>Retrospective nature of the study, lack of control.</p><p><strong>Conclusions: </strong>Pathology to the PL-PIPJ can be a primary cause of lameness in horses and these structures should therefore be critically evaluated on MR examination. Differentiation between the abaxially located structures can be challenging. Periligamentous oedema is often present in cases of desmitis of the abaxially located ligaments; its presence should prompt closer assessment.</p>","PeriodicalId":11796,"journal":{"name":"Equine Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144282972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to 'Prejudicial findings regarding suitability for intended purpose during pre-purchase examinations in a mixed horse population-A retrospective observational study in the United Kingdom'.","authors":"","doi":"10.1111/evj.14544","DOIUrl":"https://doi.org/10.1111/evj.14544","url":null,"abstract":"","PeriodicalId":11796,"journal":{"name":"Equine Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144282971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of a point prevalence survey to measure antimicrobial use and antimicrobial resistance in equine veterinary hospitals.","authors":"E K Leus, N Collins, M Gruyaert, R N Kennedy, E McConnell, B C McGorum, D Luethy, M Sanz, A Versporten, A Viljoen, C H Lyle","doi":"10.1111/evj.14535","DOIUrl":"https://doi.org/10.1111/evj.14535","url":null,"abstract":"<p><strong>Background: </strong>Antimicrobial resistance (AMR) is increasingly recognised in equine medicine. Antimicrobial use (AMU) is a key driver of AMR.</p><p><strong>Objectives: </strong>To pilot a point prevalence survey (PPS), based on the Global-PPS used in human hospitals, to obtain data on antibiotic prescribing and AMR in equine hospitals and to identify targets for improvement in AMU.</p><p><strong>Study design: </strong>Point prevalence survey.</p><p><strong>Methods: </strong>Eight equine hospitals located in Australia, Belgium, South Africa, the United Kingdom and the United States were recruited. Data on AMU were collected from all in-patients on antibiotic treatment at 08h00 on four selected study days throughout the study year (2022).</p><p><strong>Results: </strong>In total, 742 patients, 310 (41.8%) surgical and 432 (58.2%) nonsurgical cases, were evaluated and 58.7% (182/310) surgical and 25.9% (112/432) nonsurgical patients were on antibiotics. The most prescribed antibiotics were penicillin, gentamicin and trimethoprim sulfonamides. In 45.2% (215/476) of prescriptions, use was prophylactic. Therapeutic use was based on a biomarker in 48.8% (127/260) of treatments. A sample was submitted for culture in 56.9% (148/260) of therapeutic treatments. A positive culture result was reported from 49.3% (73/148) of samples, with an antibiogram available for 90.4% (66/73) of the positive cultures. An antibiotic use stop/review date was not recorded in 59.5% (283/476) of uses.</p><p><strong>Main limitations: </strong>This PPS was a pilot study with a relatively small sample size and likely does not reflect AMU in all types of equine hospitals in all geographic locations.</p><p><strong>Conclusions and clinical relevance: </strong>The PPS identified multiple ways in which antibiotic prescribing could be improved. Targets identified for stewardship interventions included empiric use of European Medicines Agency Category A and B antibiotics, the high prevalence of prophylaxis and the lack of use of a stop/review date. The survey could be used as a repeatable tool to assess stewardship interventions in equine hospitals.</p>","PeriodicalId":11796,"journal":{"name":"Equine Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144224781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Equine veterinarians' care priorities regarding vaccination, colic, lameness and pre-purchase scenarios.","authors":"Yteke Elte, Inga Wolframm, Hans Vernooij, Mirjam Nielen, René van Weeren","doi":"10.1111/evj.14537","DOIUrl":"https://doi.org/10.1111/evj.14537","url":null,"abstract":"<p><strong>Background: </strong>Equine veterinarians play a crucial role in maintaining equine health and ensuring client satisfaction. Understanding their perspectives on key aspects of veterinary care is essential for optimising outcomes for both clients and horses.</p><p><strong>Objectives: </strong>To identify and compare the importance equine veterinarians place on seven key aspects of client satisfaction in equine veterinary practice (quality of care, quality of service, horsemanship, interpersonal skills, transfer of knowledge, financial aspects and professionalism) across four different scenarios.</p><p><strong>Study design: </strong>A cross-sectional survey-based study.</p><p><strong>Methods: </strong>A total of 246 equine veterinarians participated in the online survey, which included ranking the seven aspects of equine veterinary care across four scenarios. The data were analysed using Friedman tests to assess differences within and across scenarios, followed by Wilcoxon signed-rank tests with Bonferroni correction for post-hoc comparisons. Fisher's exact test and Kruskal-Wallis tests were used to determine differences between groups of veterinarians.</p><p><strong>Results: </strong>Quality of care was ranked most important in the colic (median rank: 1, interquartile range [IQR]: 1-2) and lameness (median rank: 1, IQR: 1-2) scenarios (p < 0.001), reflecting the critical nature of these conditions. Quality of service showed no differences in ranking across the scenarios. Professionalism was ranked significantly more important in the pre-purchase scenario (median rank: 2, IQR: 1-3) compared to other scenarios (p < 0.001). Financial aspects were consistently ranked least important (median rank: 7, IQR: 6-7, p < 0.001). No differences in ranking were found between different groups of veterinarians.</p><p><strong>Main limitations: </strong>Participants may not accurately represent the diversity and characteristics of the entire equine veterinary population. The scenarios do not fully encompass the diversity of equine veterinary practice.</p><p><strong>Conclusions: </strong>Equine veterinarians prioritise quality of care, quality of service and professionalism in their practice, with some variations depending on the clinical scenario. Financial aspects were consistently given the lowest priority.</p>","PeriodicalId":11796,"journal":{"name":"Equine Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spinal articular dysfunction is common in athletic horses.","authors":"Claudia R Patricio, Gustavo H Z Winter, Petra Garbade","doi":"10.1111/evj.14541","DOIUrl":"https://doi.org/10.1111/evj.14541","url":null,"abstract":"<p><strong>Background: </strong>Spinal articular dysfunction disrupts normal neural function and may lead to stiffness, pain or poor performance. Back pain is common in equine athletes, and it is a common complaint by horse owners requesting chiropractic evaluations.</p><p><strong>Objectives: </strong>To describe the prevalence of spinal articular dysfunction in showjumping horses.</p><p><strong>Study design: </strong>Retrospective analysis of clinical records.</p><p><strong>Methods: </strong>Records from 3 years of examinations in horses, from beginners to high-performance levels. Each horse had 30 spinal segments evaluated for the presence of dysfunctional articulations. Exams were performed by a certified International Veterinary Chiropractic Association veterinarian. Data recorded included age, sex, complaint and history of previous veterinary chiropractic examinations. Descriptive and statistical analysis was performed by age groups: G1 up to 6 years old, G2 from 7 to 10 years, G3 from 11 to 14 years, and G4 from 15 years and above. Significance was set as p < 0.05; results were presented as mean ± SD.</p><p><strong>Results: </strong>Four hundred and ninety-two jumping horses were included (4-19 years old). On average, animals had 11.9 (±3.5) dysfunctional spinal segments. The minimal number observed was 2 and the maximum was 23. No animals were free of spinal dysfunction, and 442 (89.8%) were found to have segmental dysfunction in all 3 spinal regions. The most affected vertebrae were L3, L2, L4, C1 and T7. Dysfunctional segments in the cervical region were diagnosed less frequently in G1 horses (p < 0.05).</p><p><strong>Main limitations: </strong>Objective pain measurements were unavailable. Lameness, when present, was not graded and was not directly correlated with spinal dysfunction.</p><p><strong>Conclusions: </strong>Jumping horses had a high prevalence of spinal articular dysfunction, mainly in the lumbar spine, thoracic sling area and atlanto-occipital joint. The prevalence of dysfunction of the cervical spine increases with age. No equine athlete in this study was free of spinal articular dysfunction.</p>","PeriodicalId":11796,"journal":{"name":"Equine Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood amino acid changes associated with Lawsonia intracellularis infection in horses.","authors":"Yuya Mizuguchi, Hidekazu Niwa, Hiroki Inoue, Hidetomo Iwano","doi":"10.1111/evj.14533","DOIUrl":"https://doi.org/10.1111/evj.14533","url":null,"abstract":"<p><strong>Background: </strong>Hypoproteinaemia/hypoalbuminaemia is a typical clinical feature of Lawsonia intracellularis infection in horses, but amino acid perturbations in these horses have not been investigated.</p><p><strong>Objectives: </strong>Clarifying blood amino acid levels in horses suffering from Lawsonia intracellularis infection to identify novel aspects of the disease.</p><p><strong>Study design: </strong>Retrospective observational study.</p><p><strong>Methods: </strong>A total of 135 serum samples collected from horses from 59 farms were used in this study. Horses diagnosed with the clinical form of equine proliferative enteropathy (EPE) were enrolled as a clinical group (n = 46). Clinically normal herd mates of EPE patients were assigned to a subclinical EPE group (n = 22) or Lawsonia intracellularis exposure group (n = 41). Horses from EPE-naïve farms were used for control horses (n = 26). Amino acid profiles of each group were reviewed through principal component analysis, and subsequently, the Steel-Dwass multiple comparison test or Tukey's honestly significant difference test was used to clarify substantial amino acid changes characteristic of the horse populations.</p><p><strong>Results: </strong>Significant perturbations in amino acid concentrations were observed in horses with clinical and subclinical forms of the disease and in the exposure group compared to control horses. Asparagine, glutamine, aspartic acid, glutamic acid, and glycine were significantly perturbed in the clinical, subclinical, and exposure groups compared to the control group, while alanine, citrulline, and tryptophan were characteristically perturbed in the clinical group relative to the other horse groups.</p><p><strong>Main limitations: </strong>Variability of the original farms from which study populations were derived due to the retrospective nature of the study might have influenced the aminogram.</p><p><strong>Conclusions: </strong>Amino acid concentrations show substantial perturbations in relation to the clinical status of EPE. Evaluation of the aminograms of horses with Lawsonia intracellularis infection provides novel information on this disease, which would be of clinical and, potentially, therapeutic relevance.</p>","PeriodicalId":11796,"journal":{"name":"Equine Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144127002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The proteomic differences and expression of fatty acid-binding protein 6 (FABP6) associated with gastrointestinal injury in horses with oral administration of a clinical dose of phenylbutazone.","authors":"Ruethaiwan Vinijkumthorn, Nawarus Prapaiwan, Thanapon Chotikaprakal, Phirom Prompiram, Narumon Phaonakrop, Sittiruk Roytrakul, Parichart Tesena","doi":"10.1111/evj.14538","DOIUrl":"https://doi.org/10.1111/evj.14538","url":null,"abstract":"<p><strong>Background: </strong>Phenylbutazone (PBZ) can potentially induce gastrointestinal ulceration, and early detection of PBZ-induced gastroenteropathy will be useful for the diagnosis, treatment, and prevention of PBZ toxicity.</p><p><strong>Objectives: </strong>To identify putative proteins associated with equine gastric ulcer syndrome after clinical dose (4.4 mg/kg) administration of PBZ by proteomic study.</p><p><strong>Study design: </strong>In vivo experiments.</p><p><strong>Methods: </strong>Proteomic analysis using LC-MS/MS compared protein expression in serum and faeces of seven PBZ-treated horses with seven placebo-treated controls, and a novel putative biomarker was validated via enzyme-linked immunosorbent assay.</p><p><strong>Results: </strong>Differentially expressed proteins (DEPs) analysis on 5298 serum annotated proteins and 3538 faecal annotated proteins using the DESeq2 were performed between the control and treatment of EGUS groups. The results showed a list of 226 and 181 significant proteins in serum and faecal samples, respectively with a p adjust value <0.05. The proteomic serum and faeces samples were integrated into STITCH to illustrate PBZ interaction with bile acid homeostasis. FABP6 was significantly increased in PBZ-treated horses. The serum FABP6 concentration in the treatment group on Day 8 (1.80 ± 0.37 ng/mL) was higher than on Day 0 (1.15 ± 0.33 ng/mL, p = 0.01, 95% CI [-1.07, -0.25]). On Day 8, the serum FABP6 concentration in the treatment group was also higher than the control group (1.20 ± 0.48 ng/mL; p = 0.02, 95% CI [-1.10, -0.11]).</p><p><strong>Main limitations: </strong>Validation of all expressed proteins is a main limitation.</p><p><strong>Conclusions: </strong>Administration of PBZ at a clinical dose of 4.4 mg/kg twice daily for 7 days may cause gastric mucosal damage. PBZ treatment increased the expression of SLC10A1 and FABP6, suggesting that early gastric mucosal injury may be linked to the bile acid pathway. Bile acids could potentially exacerbate PBZ-induced EGUS.</p>","PeriodicalId":11796,"journal":{"name":"Equine Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Workshop Report: 2025 Dorothy Russell Havemeyer Foundation Meeting on Equine Gastric Ulcer Syndrome: Advances in the Field","authors":"Benjamin W. Sykes,&nbsp;Gayle D. Hallowell,&nbsp;Frank M. Andrews","doi":"10.1111/evj.14526","DOIUrl":"10.1111/evj.14526","url":null,"abstract":"","PeriodicalId":11796,"journal":{"name":"Equine Veterinary Journal","volume":"57 4","pages":"823-826"},"PeriodicalIF":2.4,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding antimicrobial use by equine owners in Wales: Using cross-sectional survey and semi-structured interviews.","authors":"Rebekah B Stuart, Fleur Miles-Farrier, Alison M Bard, Gwen Rees","doi":"10.1111/evj.14522","DOIUrl":"https://doi.org/10.1111/evj.14522","url":null,"abstract":"<p><strong>Background: </strong>Antimicrobial resistance (AMR) is an increasingly serious threat to human and animal health. Antimicrobial use (AMU) in horses is gathering research interest, although there remain significant evidence gaps. Currently, there is scant qualitative research into equine owners' use of antimicrobials, specifically antibiotics, hindering the design of evidence-based stewardship interventions and policies.</p><p><strong>Objectives: </strong>To understand Welsh equine owners' views and behaviours relating to antimicrobial usage.</p><p><strong>Study design: </strong>Cross sectional survey and qualitative data collection and analysis.</p><p><strong>Methods: </strong>An online survey (n = 319) and semi-structured interviews (n = 21) were conducted with Welsh equine owners. The survey examined participant knowledge of and relationship with their horse(s), sourcing of antibiotics, owner-vet interactions on antibiotic prescribing, antibiotic usage, and their understanding of AMR. Semi-structured in-depth interviews further explored horse owner perspectives, experiences, and decision-making relating to these areas, to add nuance and depth to quantitative data. Survey data were descriptively analysed, and interview data were coded and qualitatively analysed using a thematic approach.</p><p><strong>Results: </strong>Welsh equine owners regarded their horses as members of the family (84.8%). Most sourced antibiotics from their vet (68.9%) with a minority (5.1%) never having done so or having used antibiotics left over (16.6%) and 13.6% would consider changing veterinary practice if they did not receive antibiotics when they requested them. Interview data suggest that antibiotic use was shaped by (i) key relationships of care (human-animal and owner-vet); (ii) competing priorities (treatment need versus ease of administration); and (iii) imperfect comprehension (education, information, AMU/AMR knowledge).</p><p><strong>Main limitations: </strong>Potential self-selection bias of respondents due to the voluntary nature of participation.</p><p><strong>Conclusions: </strong>This study highlights variations in the horse-owner relationship, conflicting priorities involved in horse ownership, and the quality of vet-client relationships which may influence treatment decision-making. It raises some concerns about the sourcing of antibiotics and variable understanding of AMR, with important implications for antimicrobial stewardship and educational priorities.</p>","PeriodicalId":11796,"journal":{"name":"Equine Veterinary Journal","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical insights: Advances in equine adult critical care","authors":"Kate F. McGovern","doi":"10.1111/evj.14523","DOIUrl":"10.1111/evj.14523","url":null,"abstract":"","PeriodicalId":11796,"journal":{"name":"Equine Veterinary Journal","volume":"57 4","pages":"820-822"},"PeriodicalIF":2.4,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}