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Prevalence of mental disorders in adult populations from the Global South following exposure to natural hazards: a meta-analysis. 全球南部成人遭受自然灾害后精神失常的发生率:荟萃分析。
IF 5.9 2区 医学
Epidemiology and Psychiatric Sciences Pub Date : 2024-11-28 DOI: 10.1017/S2045796024000672
A Kip, S Valencia, E Glunz, S R Lowe, K-P Tam, N Morina
{"title":"Prevalence of mental disorders in adult populations from the Global South following exposure to natural hazards: a meta-analysis.","authors":"A Kip, S Valencia, E Glunz, S R Lowe, K-P Tam, N Morina","doi":"10.1017/S2045796024000672","DOIUrl":"10.1017/S2045796024000672","url":null,"abstract":"<p><strong>Aims: </strong>Although natural hazards (e.g., tropical cyclones, earthquakes) disproportionately affect developing countries, most research on their mental health impact has been conducted in high-income countries. We aimed to summarize prevalences of mental disorders in Global South populations (classified according to the United Nations Human Development Index) affected by natural hazards.</p><p><strong>Methods: </strong>To identify eligible studies for this meta-analysis, we searched MEDLINE, PsycINFO and Web of Science up to February 13, 2024, for observational studies with a cross-sectional or longitudinal design that reported on at least 100 adult survivors of natural hazards in a Global South population and assessed mental disorders with a validated instrument at least 1 month after onset of the hazard. Main outcomes were the short- and long-term prevalence estimates of mental disorders. The project was registered on the International Prospective Register of Systematic Reviews (CRD42023396622).</p><p><strong>Results: </strong>We included 77 reports of 75 cross-sectional studies (six included a non-exposed control group) comprising 82,400 individuals. We found high prevalence estimates for post-traumatic stress disorder (PTSD) in the general population (26.0% [95% CI 18.5-36.3]; <i>I</i><sup>2</sup> = 99.0%) and depression (21.7% [95% CI 10.5-39.6]; <i>I</i><sup>2</sup> = 99.2%) during the first year following the event, with similar prevalences observed thereafter (i.e., 26.0% and 23.4%, respectively). Results were similar for regions with vs. without recent armed conflict. In displaced samples, the estimated prevalence for PTSD was 46.5% (95% CI 39.0-54.2; <i>k</i> = 6; <i>I</i><sup>2</sup> = 93.3). We furthermore found higher symptom severity in exposed, versus unexposed, individuals. Data on other disorders were scarce, apart from short-term prevalence estimates of generalised anxiety disorder (15.9% [95% CI 4.7-42.0]; <i>I</i><sup>2</sup> = 99.4).</p><p><strong>Conclusions: </strong>Global South populations exposed to natural hazards report a substantial burden of mental disease. These findings require further attention and action in terms of implementation of mental health policies and low-threshold interventions in the Global South in the aftermath of natural hazards. However, to accurately quantify the true extent of this public health challenge, we need more rigorous, well-designed epidemiological studies across diverse regions. This will enable informed decision making and resource allocation for those in need.</p>","PeriodicalId":11787,"journal":{"name":"Epidemiology and Psychiatric Sciences","volume":"33 ","pages":"e68"},"PeriodicalIF":5.9,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142738826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Michaela Polacek. 'I had to eat myself up on the left, now I'm only on the right'. 米凯拉-波拉切克我不得不在左边把自己吃掉,现在我只在右边"。
IF 5.9 2区 医学
Epidemiology and Psychiatric Sciences Pub Date : 2024-11-27 DOI: 10.1017/S2045796024000714
Florian Reese
{"title":"Michaela Polacek. 'I had to eat myself up on the left, now I'm only on the right'.","authors":"Florian Reese","doi":"10.1017/S2045796024000714","DOIUrl":"https://doi.org/10.1017/S2045796024000714","url":null,"abstract":"","PeriodicalId":11787,"journal":{"name":"Epidemiology and Psychiatric Sciences","volume":"33 ","pages":"e72"},"PeriodicalIF":5.9,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142727277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A longitudinal birth cohort study of child maltreatment and mental disorders using linked statewide child protection and administrative health data for 83,050 Queensland residents from 1983 to 2014. 一项关于儿童虐待和精神障碍的出生队列纵向研究,使用的是 1983 年至 2014 年期间全州 83,050 名昆士兰居民的儿童保护和行政健康数据。
IF 5.9 2区 医学
Epidemiology and Psychiatric Sciences Pub Date : 2024-11-20 DOI: 10.1017/S204579602400074X
Steve Kisely, Stuart Leske, James Ogilvie, Carleen Thompson, Dan Siskind, Troy Allard
{"title":"A longitudinal birth cohort study of child maltreatment and mental disorders using linked statewide child protection and administrative health data for 83,050 Queensland residents from 1983 to 2014.","authors":"Steve Kisely, Stuart Leske, James Ogilvie, Carleen Thompson, Dan Siskind, Troy Allard","doi":"10.1017/S204579602400074X","DOIUrl":"10.1017/S204579602400074X","url":null,"abstract":"<p><strong>Aims: </strong>Most information about the association between childhood maltreatment (CM) and subsequent psychiatric morbidity is based on retrospective self-reports. Findings from longitudinal studies using prospective reports to statutory agencies may be subject to attrition. We therefore compared the prevalence to age 30 of inpatient psychiatric diagnoses in those who experienced agency-reported CM with those of the rest of the cohort using administrative data to minimise loss to follow-up.</p><p><strong>Methods: </strong>We used linked administrative data for two birth cohorts of all individuals born in Queensland, Australia in 1983 and 1984 (<i>N</i> = 83,050) and followed to age 30 years. This was the entire cohort aside from 312 people who died. Information on CM came from statewide child protection data and psychiatric diagnoses from all public and private hospital admissions in Queensland.</p><p><strong>Results: </strong>On adjusted analyses, the 4,703 participants (5.7%) who had been notified to the statewide child protection authority had three to eight times the odds of being admitted for any of the following psychiatric diagnoses by age 30 years old: schizophrenia-spectrum disorders, bipolar affective disorders, depression, anxiety and post-traumatic stress disorders (PTSD). There were similar findings for all the CM subtypes. Associations were especially strong for PTSD with between a seven - and nine-fold increase in the odds of admission.</p><p><strong>Conclusions: </strong>This is one of the largest studies of the long-term effects of CM, covering an entire jurisdiction. All types of maltreatment are significantly related to a range of psychiatric disorders requiring hospitalisation. Early identification, intervention and providing appropriate support to individuals who have experienced CM may help mitigate the long-term consequences and reduce the risk of subsequent mental health problems.</p>","PeriodicalId":11787,"journal":{"name":"Epidemiology and Psychiatric Sciences","volume":"33 ","pages":"e69"},"PeriodicalIF":5.9,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A longitudinal network of psychotic-like experiences, depressive and anxiety symptoms, and adverse life events: a cohort study of 3,358 college students. 类似精神病的经历、抑郁和焦虑症状以及不良生活事件的纵向网络:一项针对 3,358 名大学生的队列研究。
IF 5.9 2区 医学
Epidemiology and Psychiatric Sciences Pub Date : 2024-11-18 DOI: 10.1017/S2045796024000726
Meng Sun, Heng Sun, Zijuan Ma, Shaoling Zhong, Xinhu Yang, Yue Li, Hongling Zhou, Liang Zhou
{"title":"A longitudinal network of psychotic-like experiences, depressive and anxiety symptoms, and adverse life events: a cohort study of 3,358 college students.","authors":"Meng Sun, Heng Sun, Zijuan Ma, Shaoling Zhong, Xinhu Yang, Yue Li, Hongling Zhou, Liang Zhou","doi":"10.1017/S2045796024000726","DOIUrl":"10.1017/S2045796024000726","url":null,"abstract":"<p><strong>Aims: </strong>Psychotic-like experiences (PLEs), especially for persistent PLEs, are highly predictive of subsequent mental health problems. Hence, it is crucial to explore the psychopathological associations underlying the occurrence and persistence of PLEs. This study aimed to explore the above issues through a longitudinal dynamic network approach among PLEs and psychological and psychosocial factors.</p><p><strong>Methods: </strong>A total of 3,358 college students completed two waves of online survey (from Oct 2021 to Oct 2022). Socio-demographic information was collected at baseline, and PLEs, depressive and anxiety symptoms, and adverse life events were assessed in both waves. Cross-lagged panel network analyses were used to establish networks among individuals with baseline PLEs as well as those without.</p><p><strong>Results: </strong>At baseline, 455(13.5%) students were screened positive for PLEs. Distinct dynamic network structures were revealed among participants with baseline PLEs and those without. While 'psychomotor disturbance' had the strongest connection with PLEs in participants with baseline PLEs, 'suicide/self-harm' was most associated with PLEs in those without. Among all three subtypes of PLEs, bizarre experiences and persecutory ideation were the most affected nodes by other constructs in participants with baseline PLEs and those without, respectively. Additionally, wide interconnections within the PLEs construct existed only among participants without baseline PLEs.</p><p><strong>Conclusions: </strong>The study provides time-variant associations between PLEs and depressive symptoms, anxiety symptoms, and adverse life events using network structures. These findings help to reveal the crucial markers of the occurrence and persistence of PLEs, and shed high light on future intervention aimed to prevent and relieve PLEs.</p>","PeriodicalId":11787,"journal":{"name":"Epidemiology and Psychiatric Sciences","volume":"33 ","pages":"e64"},"PeriodicalIF":5.9,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142647058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hospitalization for SARS-CoV-2 and the risk of self-harm readmission: a French nationwide retrospective cohort study. SARS-CoV-2住院治疗与自残再入院风险:一项法国全国性回顾性队列研究。
IF 5.9 2区 医学
Epidemiology and Psychiatric Sciences Pub Date : 2024-11-14 DOI: 10.1017/S2045796024000568
Jean-Christophe Chauvet-Gelinier, Jonathan Cottenet, Fabrice Jollant, Catherine Quantin
{"title":"Hospitalization for SARS-CoV-2 and the risk of self-harm readmission: a French nationwide retrospective cohort study.","authors":"Jean-Christophe Chauvet-Gelinier, Jonathan Cottenet, Fabrice Jollant, Catherine Quantin","doi":"10.1017/S2045796024000568","DOIUrl":"https://doi.org/10.1017/S2045796024000568","url":null,"abstract":"<p><strong>Aims: </strong>The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on the risk of self-harming behaviours warrants further investigation. Here, we hypothesized that people with a history of hospitalization for self-harm may be particularly at risk of readmission in case of SARS-CoV-2 hospitalization.</p><p><strong>Methods: </strong>We conducted a retrospective analysis based on the French national hospitalization database. We identified all patients hospitalized for deliberate self-harm (10th edition of the International Classification of Diseases codes X60-X84) between March 2020 and March 2021. To study the effect of SARS-CoV-2 hospitalization on the risk of readmission for self-harm at 1-year of the inclusion, we performed a multivariable Fine and Gray model considering hospital death as a competing event.</p><p><strong>Results: </strong>A total of 61,782 individuals were hospitalized for self-harm. During the 1-year follow-up, 9,403 (15.22%) were readmitted for self-harm. Between inclusion and self-harm readmission or the end of follow-up, 1,214 (1.96% of the study cohort) were hospitalized with SARS-CoV-2 (mean age 60 years, 52.9% women) while 60,568 were not (mean age 45 years, 57% women). Multivariate models revealed that the factors independently associated with self-harm readmission were: hospitalization with SARS-CoV-2 (adjusted hazard ratio (aHR) = 3.04 [2.73-3.37]), psychiatric disorders (aHR = 1.61 [1.53-1.69]), self-harm history (aHR = 2.00 [1.88-2.04]), intensive care and age above 80.</p><p><strong>Conclusions: </strong>In hospitalized people with a personal history of self-harm, infection with SARS-CoV-2 increased the risk of readmission of self-harm, with an effect that seemed to add to the effect of a history of mental disorders, with an equally significant magnitude. Infection may be a significantly stressful condition that precipitates self-harming acts in vulnerable individuals. Clinicians should pay particular attention to the emergence of suicidal ideation in these patients in the aftermath of SARS-CoV-2 infection.</p>","PeriodicalId":11787,"journal":{"name":"Epidemiology and Psychiatric Sciences","volume":"33 ","pages":"e65"},"PeriodicalIF":5.9,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142615493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heterogeneity in 10-year course trajectories of moderate to severe major depressive disorder among veterans. 退伍军人中度至重度重度抑郁症 10 年病程轨迹的异质性。
IF 5.9 2区 医学
Epidemiology and Psychiatric Sciences Pub Date : 2024-11-13 DOI: 10.1017/S2045796024000465
V Panaite, S L Luther, D K Finch, N J Cohen, S K Schultz, A Tsalatsanis, P N Pfeiffer
{"title":"Heterogeneity in 10-year course trajectories of moderate to severe major depressive disorder among veterans.","authors":"V Panaite, S L Luther, D K Finch, N J Cohen, S K Schultz, A Tsalatsanis, P N Pfeiffer","doi":"10.1017/S2045796024000465","DOIUrl":"https://doi.org/10.1017/S2045796024000465","url":null,"abstract":"<p><strong>Aims: </strong>Epidemiological studies show that despite the episodic nature, the long-term trajectory of depression can be variable. This study evaluated the heterogeneity of 10-year trajectory of major depressive disorder (MDD) related service utilization and associated clinical characteristics among US Veterans with a first diagnosis after 9/11.</p><p><strong>Methods: </strong>Using a cohort design, electronic health record data for 293,265 Operation Enduring Freedom and Iraqi Freedom (OEF/OIF) Veterans were extracted to identify those with MDD between 2001 and 2021 with a full preceding year of clinical data and 10 years following the diagnosis. Latent class growth analysis compared clinical characteristics associated with four depression trajectories. Across all Veterans Affairs (VA)hospitals, 25,307 Veterans met our inclusion criteria. Demographic and clinical information from medical records was extracted and used as predictors of depression 10-year trajectories.</p><p><strong>Results: </strong>Among the study cohort (<i>N</i> = 25,307), 27.7% were characterized by brief contact, 41.7% were later re-entry, 17.6% were persistent contact and 12.9% were prolonged initial contact for depression related services. Compared to Veterans with trajectories showing brief contact, those with protracted treatment (persistent or prolonged initial contact) were more likely to be diagnosed with comorbid posttraumatic stress disorder (PTSD) and with MDD that was moderate to severe or recurrent.</p><p><strong>Conclusions: </strong>Depression is associated with a range of treatment trajectories. The persistent and prolonged initial contact trajectories may have distinct characteristics and uniquely high resource utilization and disability income. We can anticipate that patients with comorbid PTSD may need longer-term care which has implications for brief models of care.</p>","PeriodicalId":11787,"journal":{"name":"Epidemiology and Psychiatric Sciences","volume":"33 ","pages":"e67"},"PeriodicalIF":5.9,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142615517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rethinking Outsider Art in the digital age: an overview of Cara Macwilliam's artistic practice. 反思数字时代的局外人艺术:Cara Macwilliam 的艺术实践概述。
IF 5.9 2区 医学
Epidemiology and Psychiatric Sciences Pub Date : 2024-11-13 DOI: 10.1017/S2045796024000702
Isil Ezgi Celik
{"title":"Rethinking Outsider Art in the digital age: an overview of Cara Macwilliam's artistic practice.","authors":"Isil Ezgi Celik","doi":"10.1017/S2045796024000702","DOIUrl":"https://doi.org/10.1017/S2045796024000702","url":null,"abstract":"","PeriodicalId":11787,"journal":{"name":"Epidemiology and Psychiatric Sciences","volume":"33 ","pages":"e66"},"PeriodicalIF":5.9,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142615495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The public health significance of prior homelessness: findings on multimorbidity and mental health from a nationally representative survey. 以前无家可归对公共健康的意义:一项全国代表性调查对多病症和心理健康的发现。
IF 5.9 2区 医学
Epidemiology and Psychiatric Sciences Pub Date : 2024-11-08 DOI: 10.1017/S2045796024000659
N Chilman, P Schofield, S McManus, A Ronaldson, A Stagg, J Das-Munshi
{"title":"The public health significance of prior homelessness: findings on multimorbidity and mental health from a nationally representative survey.","authors":"N Chilman, P Schofield, S McManus, A Ronaldson, A Stagg, J Das-Munshi","doi":"10.1017/S2045796024000659","DOIUrl":"https://doi.org/10.1017/S2045796024000659","url":null,"abstract":"<p><strong>Aims: </strong>The associations of prior homelessness with current health are unknown. Using nationally representative data collected in private households in England, this study aimed to examine Common Mental Disorders (CMDs), physical health, alcohol/substance dependence, and multimorbidities in people who formerly experienced homelessness compared to people who never experienced homelessness.</p><p><strong>Methods: </strong>This cross-sectional study utilised data from the 2007 and 2014 Adult Psychiatric Morbidity Surveys. Former homelessness and current physical health problems were self-reported. Current CMDs, alcohol dependence and substance dependence were ascertained using structured validated scales. Survey-weighted logistic regression was used to compare multimorbidities (conditions in combination) for participants who formerly experienced homelessness with those who had never experienced homelessness, adjusting for sociodemographic characteristics, smoking status and adverse experiences. Population attributable fractions (PAFs) were calculated.</p><p><strong>Results: </strong>Of 13,859 people in the sample, 535 formerly experienced homelessness (3.6%, 95% CI 3.2-4.0). 44.8% of people who formerly experienced homelessness had CMDs (95% CI 40.2-49.5), compared to 15.0% (95% CI 14.3-15.7) for those who had never experienced homelessness. There were substantial associations between prior homelessness and physical multimorbidity (adjusted odds ratio [aOR] 1.98, 95% CI 1.53-2.57), CMD-physical multimorbidity (aOR 3.43, 95% CI 2.77-4.25), CMD-alcohol/substance multimorbidity (aOR 3.53, 95% CI 2.49-5.01) and trimorbidity (CMD-alcohol/substance-physical multimorbidity) (aOR 3.26, 95% CI 2.20-4.83), in models adjusting for sociodemographic characteristics and smoking. After further adjustment for adverse experiences, associations attenuated but persisted for physical multimorbidity (aOR 1.40, 95% CI 1.10-1.79) and CMD-physical multimorbidity (aOR 1.55, 95% CI 1.20-2.00). The largest PAFs were observed for CMD-alcohol/substance multimorbidity (17%) and trimorbidity (16%).</p><p><strong>Conclusions: </strong>Even in people currently rehoused, marked inequities across multimorbidities remained evident, highlighting the need for longer-term integrated support for people who have previously experienced homelessness.</p>","PeriodicalId":11787,"journal":{"name":"Epidemiology and Psychiatric Sciences","volume":"33 ","pages":"e63"},"PeriodicalIF":5.9,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A guide for planning triangulation studies to investigate complex causal questions in behavioural and psychiatric research. 在行为学和精神病学研究中,规划三角测量研究以调查复杂因果问题的指南。
IF 5.9 2区 医学
Epidemiology and Psychiatric Sciences Pub Date : 2024-11-07 DOI: 10.1017/S2045796024000623
Jorien L Treur, Eva Lukas, Hannah M Sallis, Robyn E Wootton
{"title":"A guide for planning triangulation studies to investigate complex causal questions in behavioural and psychiatric research.","authors":"Jorien L Treur, Eva Lukas, Hannah M Sallis, Robyn E Wootton","doi":"10.1017/S2045796024000623","DOIUrl":"10.1017/S2045796024000623","url":null,"abstract":"<p><strong>Aims: </strong>At the basis of many important research questions is causality - does X causally impact Y? For behavioural and psychiatric traits, answering such questions can be particularly challenging, as they are highly complex and multifactorial. 'Triangulation' refers to prospectively choosing, conducting and integrating several methods to investigate a specific causal question. If different methods, with different sources of bias, all indicate a causal effect, the finding is much less likely to be spurious. While triangulation can be a powerful approach, its interpretation differs across (sub)fields and there are no formal guidelines. Here, we aim to provide clarity and guidance around the process of triangulation for behavioural and psychiatric epidemiology, so that results of existing triangulation studies can be better interpreted, and new triangulation studies better designed.</p><p><strong>Methods: </strong>We first introduce the concept of triangulation and how it is applied in epidemiological investigations of behavioural and psychiatric traits. Next, we put forth a systematic step-by-step guide, that can be used to design a triangulation study (accompanied by a worked example). Finally, we provide important general recommendations for future studies.</p><p><strong>Results: </strong>While the literature contains varying interpretations, triangulation generally refers to an investigation that assesses the robustness of a potential causal finding by explicitly combining different approaches. This may include multiple types of statistical methods, the same method applied in multiple samples, or multiple different measurements of the variable(s) of interest. In behavioural and psychiatric epidemiology, triangulation commonly includes prospective cohort studies, natural experiments and/or genetically informative designs (including the increasingly popular method of Mendelian randomization). The guide that we propose aids the planning and interpreting of triangulation by prompting crucial considerations. Broadly, its steps are as follows: determine your causal question, draw a directed acyclic graph, identify available resources and samples, identify suitable methodological approaches, further specify the causal question for each method, explicate the effects of potential biases and, pre-specify expected results. We illustrated the guide's use by considering the question: 'Does maternal tobacco smoking during pregnancy cause offspring depression?'.</p><p><strong>Conclusions: </strong>In the current era of big data, and with increasing (public) availability of large-scale datasets, triangulation will become increasingly relevant in identifying robust risk factors for adverse mental health outcomes. Our hope is that this review and guide will provide clarity and direction, as well as stimulate more researchers to apply triangulation to causal questions around behavioural and psychiatric traits.</p>","PeriodicalId":11787,"journal":{"name":"Epidemiology and Psychiatric Sciences","volume":"33 ","pages":"e61"},"PeriodicalIF":5.9,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7616800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surge in antidepressant usage among adolescents and young adults during the COVID-19 pandemic: insights from an interrupted time series analysis. COVID-19大流行期间青少年和年轻人使用抗抑郁药的激增:间断时间序列分析的启示。
IF 5.9 2区 医学
Epidemiology and Psychiatric Sciences Pub Date : 2024-11-07 DOI: 10.1017/S2045796024000647
Zeno Di Valerio, Daniela Fortuna, Marco Montalti, Lucia Alberghini, Anna Caterina Leucci, Alessio Saponaro, Elisa Sangiorgi, Elena Berti, Maurizia Rolli, Dario Tedesco
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