Medica Hospitalia : Journal of Clinical Medicine最新文献

筛选
英文 中文
Metastasis Kanker Payudara Berdasarkan Subtipe Molekuler di RSUD Dr. H. Abdul Moeloek Lampung 基于 RSUD 分子亚型的乳腺癌转移 H. Abdul Moeloek Lampung 博士
Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-11-29 DOI: 10.36408/mhjcm.v10i3.904
Nurmayeni, Nurul Islamy, A. Tjiptaningrum, Bintang Abadi Siregar, Adityarini Kusumaningtyas, I. Windarti
{"title":"Metastasis Kanker Payudara Berdasarkan Subtipe Molekuler di RSUD Dr. H. Abdul Moeloek Lampung","authors":"Nurmayeni, Nurul Islamy, A. Tjiptaningrum, Bintang Abadi Siregar, Adityarini Kusumaningtyas, I. Windarti","doi":"10.36408/mhjcm.v10i3.904","DOIUrl":"https://doi.org/10.36408/mhjcm.v10i3.904","url":null,"abstract":"LATAR BELAKANG : Kanker payudara merupakan kanker dengan jumlah kasus terbanyak dan menjadi salah satu penyumbang kematian utama akibat kanker di Indonesia. Kematian pada pasien kanker payudara sebagian besar disebabkan oleh metastasis. Kanker payudara secara umum dikategorikan menjadi 4 subtipe berdasarkan imunohistokimia yaitu luminal A, luminal B, HER2+, dan TNBC. TUJUAN : Untuk mengetahui pola metastasis kanker payudara berdasarkan subtipe molekuler di RSUD Dr. H. Abdul Moeloek Lampung. METODE : Penelitian ini merupakan penelitian analitik observasional dengan pendekatan cross sectional. Sampel yang digunakan berjumlah 81 orang penderita kanker payudara yang terdata pada bagian rekam medis RSUD Dr. H. Abdul Moeloek Lampung pada tahun 2013 – 2021. Hubungan antara subtipe kanker payudara dengan kejadian dan lokasi metastasis diuji menggunakan uji Chi Square. HASIL :  Penelitian ini menemukan adanya hubungan antara subtipe kanker payudara dengan kejadian metastasis (p <0.05). Subtipe TNBC memiliki tingkat metastasis yang lebih sering (34,5%) dibandingkan subtipe lainnya (luminal B 31%, luminal A 20,7% dan HER2+ 13,8%). Penelitian ini juga mengungkap adanya hubungan antara status ER dengan kejadian metastasis (p <0.05). Subtipe luminal A cenderung bermetastasis ke hepar, luminal B cenderung bermetastasis ke tulang, HER2+ cenderung bermetastasis ke paru dan hepar, sedangkan TNBC cenderung bermetastasis ke paru. Namun demikian, tidak ditemukan adanya hubungan antara subtipe kanker payudara dengan lokasi metastasis. KESIMPULAN : Terdapat hubungan antara subtipe kanker payudara dengan kejadian metastasis.","PeriodicalId":117574,"journal":{"name":"Medica Hospitalia : Journal of Clinical Medicine","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139212301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Full Text Volume 10 Number 2 July 2023 全文第10卷第2期2023年7月
Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-07-31 DOI: 10.36408/mhjcm.v10i2.1010
Kariadi General Hospital
{"title":"Full Text Volume 10 Number 2 July 2023","authors":"Kariadi General Hospital","doi":"10.36408/mhjcm.v10i2.1010","DOIUrl":"https://doi.org/10.36408/mhjcm.v10i2.1010","url":null,"abstract":"Full Text Volume 10 Number 2 July 2023","PeriodicalId":117574,"journal":{"name":"Medica Hospitalia : Journal of Clinical Medicine","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125510928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship Between Serum Folic Acid Levels With The Cognitive Function of The Elderly 血清叶酸水平与老年人认知功能的关系
Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-07-31 DOI: 10.36408/mhjcm.v10i2.891
H. Hermanto, Hexanto Muhartomo, A. Husni, Maria Immaculata Widiastuty, Herlina Suryawati, Arinta Puspita Wati
{"title":"Relationship Between Serum Folic Acid Levels With The Cognitive Function of The Elderly","authors":"H. Hermanto, Hexanto Muhartomo, A. Husni, Maria Immaculata Widiastuty, Herlina Suryawati, Arinta Puspita Wati","doi":"10.36408/mhjcm.v10i2.891","DOIUrl":"https://doi.org/10.36408/mhjcm.v10i2.891","url":null,"abstract":"Background: Cognitive decline is a common condition that occurs in the elderly. One of the early indicators of senility is a decrease in cognitive function. Folic acid is thought to protect the arteries from damage because of homocysteine by converting homocysteine into cysteine and then excreted in the urine. Increased levels of homocysteine can interfere with vascular function and cause toxic effects on neurons thereby increasing the risk of cognitive decline.\u0000Objective: To determine the relationship between serum folic acid levels and cognitive function of the elderly.\u0000Method: Analytical descriptive research with a cross-sectional approach. The research subjects were the elderly who met the inclusion criteria and did not have exclusion criteria. The research was conducted from May to July 2022 at the Pucang Gading Nursing Home, Semarang. Serum folic acid levels were examined using the ELISA (Enzyme-linked immunosorbent assay) method. Cognitive function was assessed using the Indonesian version of the Montreal Cognitive Assessment (MoCA) simultaneously on the subject. Cognitive function is normal if the MoCA-INA value is ≥ 26 and it is said to be cognitive dysfunction if the MoCA-INA value is < 26. Data were analyzed using the Spearman test. Results are considered significant if the value of p <0.05. \u0000Result: There is a strong positive correlation between serum folic acid levels and cognitive function in the elderly (r=0.914, p<0.001). There is a relationship between educational level and cognitive function (r=0.922, p<0.001) where higher education correlates with increased cognitive function in the elderly.\u0000Conclusion: There is a significant positive correlation between serum folic acid levels and cognitive function in the elderly","PeriodicalId":117574,"journal":{"name":"Medica Hospitalia : Journal of Clinical Medicine","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121075886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship Between Serum Albumin Levels And Pulmonary Edema In Glomerulonephritis Patients 肾小球肾炎患者血清白蛋白水平与肺水肿的关系
Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-07-31 DOI: 10.36408/mhjcm.v10i2.892
Nabilla Fikria, Dwi Lestari Partingrum, Lydia Kuntjoro, Yurida Binta Meutia
{"title":"Relationship Between Serum Albumin Levels And Pulmonary Edema In Glomerulonephritis Patients","authors":"Nabilla Fikria, Dwi Lestari Partingrum, Lydia Kuntjoro, Yurida Binta Meutia","doi":"10.36408/mhjcm.v10i2.892","DOIUrl":"https://doi.org/10.36408/mhjcm.v10i2.892","url":null,"abstract":"Background: Glomerulonephritis is an inflammatory disease of the glomerulus that causes changes in permeability, changes in kidney’s structure, and function of the glomerulus. Hypoalbuminemia in glomerulonephritis can decrease oncotic pressure resulting in extravasation of fluid into the interstitium. In severe hypoalbuminemia, extravasation of fluid can result in pulmonary edema. The subjective of this study was to analyze the correlation between serum albumin and the incidence of pulmonary edema by chest x-ray in patients with glomerulonephritis.\u0000Methods: The samples of this study were collected by purposive sampling using secondary data from the medical records of Dr. Kariadi Hospital in Semarang with a total of 46 subjects from January 2016-January 2021. The serum albumin was categorized as normal if serum albumin was >3,5 g/dL, mild hypoalbuminemia if serum albumin was 2.5-3.5 g/dL and severe hypoalbuminemia if serum albumin was <2.5 g/dL.\u0000Result: Mann Whitney test showed a significant relationship between between serum albumin and the incidence of pulmonary edema by chest x-ray in patients with glomerulonephritis (p = 0.016). A higher mean rank was found in patients with pulmonary edema compared to patients without pulmonary edema.\u0000Conclusion:There is a significant relationship between serum albumin and the incidence of pulmonary edema by chest x-ray in patients with glomerulonephritis. Patients with lower serum albumin have a greater tendency to develop pulmonary edema than patients with higher serum albumin.","PeriodicalId":117574,"journal":{"name":"Medica Hospitalia : Journal of Clinical Medicine","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131594070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect Of Giving A Vibrator With A Cooler On Pain Level In Childhood With Venipuncture In Tidore Kepulauan Hospital 在Tidore Kepulauan医院给予振动器与冷却器对儿童静脉穿刺疼痛程度的影响
Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-07-31 DOI: 10.36408/mhjcm.v10i2.870
Fadila Abdullah, Nursanti Anwar
{"title":"Effect Of Giving A Vibrator With A Cooler On Pain Level In Childhood With Venipuncture In Tidore Kepulauan Hospital","authors":"Fadila Abdullah, Nursanti Anwar","doi":"10.36408/mhjcm.v10i2.870","DOIUrl":"https://doi.org/10.36408/mhjcm.v10i2.870","url":null,"abstract":"BACKGROUND : Atraumatic care is therapeutic care that is carried out as part of an intervention to remove or suppress psychological or physical stress suffered by a child. The act of minimizing pain, stress and trauma to children when given at the time of blood collection is part of the principle of atraumatic care. One of the atraumatic actions that can be performed on children is the use of a vibrator with a cooler to minimize pain when stabbing a vein\u0000AIMS : to determine the effectiveness of giving a vibrator accompanied by a cold compress against pain in children when taking venous blood.\u0000METHODS : The design of this research is true experimental with a post-test only control group design. Researchers divided into 2 groups, namely the intervention and control groups were taken randomly. Then the researcher made a vibrator with a cooler that had been previously tested on 30 adults, then after being declared to have passed the ethical study it would be applied to children when taking venous blood, assessing children's pain using the FLACC instrument (face, legs, activity, cry and controllability). The study was conducted at the Tidore Islands Hospital. Data processing was carried out previously by testing the homogeneity and normality test, if normally distributed it will use the independent t-test to assess the difference in the average of the two groups, while if it is not normally distributed it will be tested with Mann-Whitney.\u0000RESULT : The results of this study indicate that the characteristics of respondents according to age are mostly 4 years old. In the control group the average age of children is 3.87 while in the intervention group the average age of children is 3.93. Most of the experience of having blood drawn in both groups had blood drawn before. Based on gender characteristics, most of the control and intervention groups were women. There are differences in pain scores in the control and intervention groups. The mean pain score in the intervention group was 3.13 and the mean pain score in the control group was 7.87. The results of statistical tests using Mann Whitney showed that there was a significant difference in pain during venipuncture in the intervention group and the control group (p=0.013).\u0000CONCLUSION : The results of the statistical test show that there was a significant difference in pain in the intervention group and the control group (p=0.013). The use of a cooling vibrator can be an alternative to reduce pain in children during venipuncture.","PeriodicalId":117574,"journal":{"name":"Medica Hospitalia : Journal of Clinical Medicine","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124837850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wistar Rat Parietal Lobe Cell And Pain Perception Changes After Frequent Of Mobile Phone Electromagnetic Wave Expose 手机电磁波频繁暴露后Wistar大鼠顶叶细胞及痛觉变化
Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-07-31 DOI: 10.36408/mhjcm.v10i2.884
Fatiha Sri Utami Tamad, Trianggoro Budisulistyo, A. Husni, R. Retnaningsih, Herlina Suryawati, S. Suryadi
{"title":"Wistar Rat Parietal Lobe Cell And Pain Perception Changes After Frequent Of Mobile Phone Electromagnetic Wave Expose","authors":"Fatiha Sri Utami Tamad, Trianggoro Budisulistyo, A. Husni, R. Retnaningsih, Herlina Suryawati, S. Suryadi","doi":"10.36408/mhjcm.v10i2.884","DOIUrl":"https://doi.org/10.36408/mhjcm.v10i2.884","url":null,"abstract":"Background: The increasing number of mobile phone users raises concerns about the effects. Mobile phone electromagnetic wave radiation harms pain perception due to granular cell changes in the cerebral parietal cortex.\u0000Objective: To determine the effect of exposure to electromagnetic waves mobile phone on pain perception due to changes in the granular cells of the cerebral parietal cortex Wistar rats.\u0000Methods: Experimental research using randomized posttest with control group design. Samples were 28 rats divided into 4 groups. The control group was not exposed, the treatment group was exposed to 2100 MHz electromagnetic waves for 2 hours/day with a distance of 3 cm for 15 days in treatment group 1, for 30 days in treatment group 2, and 45 days in treatment group 3. Measurement of pain onset using the hot method. Changes in pain threshold were taken from the difference in pain onset after exposure to before exposure. Granular cell changes in the cerebral parietal cortex were assessed from the total score with the provisions of normal cells (sumx0), hydropic degenerated cells (sumx1), and necrotic cells (sumx2).\u0000Results: The longer the exposure to mobile phones, the higher the pain threshold and the cerebral parietal cortex granular cell damage score. There was a significant difference in pain threshold and changes in cerebral parietal cortex granular cells between groups (p=0.000). There was a significant relationship between changes in the parietal cerebral cortex granular cells and pain threshold in Wistar rats exposed to electromagnetic waves (p=0.000).\u0000Conclusion: Exposure to mobile phone electromagnetic waves affects pain perception due to changes in the granular cells of the cerebral parietal cortex in wistar rats.","PeriodicalId":117574,"journal":{"name":"Medica Hospitalia : Journal of Clinical Medicine","volume":"770 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123886419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Palliative Care Case Report: A Man with End Stage Lung Cancer with Brain Metastases 姑息治疗病例报告:1例终末期肺癌伴脑转移
Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-07-31 DOI: 10.36408/mhjcm.v10i2.901
Yanuar Ardani, H. Shatri, Rudi Putranto, Rendi Faris Anggono
{"title":"Palliative Care Case Report: A Man with End Stage Lung Cancer with Brain Metastases","authors":"Yanuar Ardani, H. Shatri, Rudi Putranto, Rendi Faris Anggono","doi":"10.36408/mhjcm.v10i2.901","DOIUrl":"https://doi.org/10.36408/mhjcm.v10i2.901","url":null,"abstract":"INTRODUCTION : Lung cancer accounts for 13% of malignancies in the world and the most common type of cancer suffered by men in Indonesia. The 5-year survival rate for patients with lung cancer is only 18.1%. About 25-30% will develop brain metastases. Overall palliative care is needed including biologically targeted therapy, chemotherapy, stereotactic radiosurgery (SRS), surgery in selected cases, and whole brain radiotherapy treatment (WBRT). Rare studies that take into account surgical palliation in advanced NSCLC. It has been demonstrated that metastaticectomy generally improves survival and, in some patients, even long-term survival.\u0000CASE REPORT : A 65-year-old male patient with Non-Small Cell Carcinoma favor Lung Adenocarcinoma and cerebellum metastases. The patient underwent surgery to remove a brain tumor. The patient received 8 radiotherapies and Erlotinib chemotherapy for 4 cycles for 6 months. The dose of Erlotinib 150g/24 hours was used in the first month. The dose was reduced in the 2nd to 6th month to 100g/24 hours. Assessment of palliative care was carried out using the Karnopsky Questionnaire, Fatigue Severity Scale (FSS), and Palliative Performance Scale (PPS).\u0000CONCLUSION : . Despite major improvements in the way lung cancer patients are treated in recent years, morbidity and death rates are still high. Palliative care (PC) is an approach to treating patients with life-threatening diseases, one of which is lung cancer","PeriodicalId":117574,"journal":{"name":"Medica Hospitalia : Journal of Clinical Medicine","volume":"128 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116062242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytokine Storm score (CSs) in COVID-19 Patients Smokers at Dr. Saiful Anwar Malang 新冠肺炎患者细胞因子风暴评分(CSs)在Saiful Anwar Malang医生诊所
Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-07-31 DOI: 10.36408/mhjcm.v10i2.902
Resti Fitriani Yuliawati, Triwahju Astuti, Y. Sugiri
{"title":"Cytokine Storm score (CSs) in COVID-19 Patients Smokers at Dr. Saiful Anwar Malang","authors":"Resti Fitriani Yuliawati, Triwahju Astuti, Y. Sugiri","doi":"10.36408/mhjcm.v10i2.902","DOIUrl":"https://doi.org/10.36408/mhjcm.v10i2.902","url":null,"abstract":"Background: After 3 years of the COVID-19 pandemic, its escalation is still causing a critical global health problem. Cytokine storm is a severe complication of COVID-19, and smoking is a risk factor for death. The prevalence of smoking in Indonesia is very high, but there is still little research on the effect of smoking on the occurrence of cytokine storms. The Cytokines Storm Score (CSs) is a quick and simple method for detecting cytokine storms early by utilizing D-dimer, lactate dehydrogenase (LDH), ferritin, and C-reactive protein (CRP) parameters.\u0000Objective: To evaluate CSs in COVID-19 patients smokers\u0000Methods: Retrospective analysis of 120 confirmed COVID-19 patients in November 2020–2021, divided into 2 groups (60 smokers and nonsmokers), male, without comorbidities. analysis using Chi-square and Mann-Whitney. Prior to the CSs examination, lymphopenia is required. CSs were positive if at least two of the D-dimer, LDH, or ferritin levels were elevated. The CRP level is measured if there is an increase in only one of these values. Elevated CRP, lymphopenia, and impaired D-Dimer, LDH, or ferritin will result in positive CSs.\u0000Results: CSs were significantly higher in smokers than non-smokers (54.5% vs. 45.5%, p = 0.024). D-dimer and CRP levels were significantly higher in smokers than non-smokers (1620 ng/mL vs. 1002.5 ng/mL, p = 0.001; and 13.8 mg/dL vs. 7.75 mg/dL, p = 0.001). Lower LDH and higher ferritin levels were not significant in smokers compared to nonsmokers (405.5 IU/L vs. 418 IU/L, p = 0.160; and 886.65 ng/mL vs. 790.5 ng/mL, p = 0.203).\u0000Conclusion: Cytokines Storm scores (CSs) increased significantly in COVID-19 patients who smoked, D-dimer and CRP levels were significantly higher in smoking COVID-19 patients compared to non-smokers","PeriodicalId":117574,"journal":{"name":"Medica Hospitalia : Journal of Clinical Medicine","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114386326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
71-year Old Male Patient with 20 Hour Onset of Infarct Stroke that was Performed with Intra-Arterial Thrombolysis, Mechanical Thrombectomy, Balloon Angioplasty, and Carotid Stenting: A Case Report 71岁男性,发病20小时梗死性脑卒中,行动脉溶栓、机械取栓、球囊血管成形术和颈动脉支架置入术1例
Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-07-31 DOI: 10.36408/mhjcm.v10i2.961
Aditya Kurnianto, Y. Andhitara, Yudistira, Jeffri Setiadi, J. Budiman
{"title":"71-year Old Male Patient with 20 Hour Onset of Infarct Stroke that was Performed with Intra-Arterial Thrombolysis, Mechanical Thrombectomy, Balloon Angioplasty, and Carotid Stenting: A Case Report","authors":"Aditya Kurnianto, Y. Andhitara, Yudistira, Jeffri Setiadi, J. Budiman","doi":"10.36408/mhjcm.v10i2.961","DOIUrl":"https://doi.org/10.36408/mhjcm.v10i2.961","url":null,"abstract":"Introduction: For above 2 decades, the definitive management for acute ischemic stroke is intravenous or intra-arterial thrombolysis (IAT), using recombinant tissue-type plasminogen activator. Recently mechanical thrombectomy (MT) was developed to overcome the problem that intravenous thrombolysis is only effective in removing large artery occlusions in the range of 10-30%. Early treatment with intra-arterial thrombolysis, permanent stent insertion and clot extraction devices evolved into the stent-retriever device used in most of the important trials and, recently, emerged aspiration tool. This case report presented 71-year-old male patient with infarct stroke who performed with MT.\u0000Case presentation: This case report presented 71-year-old male patient with the main complaint of right limbs weakness. A non-contrast head CT scan found infarction in the cortical-subcortical left parietal lobe, posterior pericornu of the right lateral ventricle and right temporal cornu periventricular; lacunar infarction in the right and left paramedian pons; old lacunar infarction in the left and right centrum semiovale, left corona radiata, right internal capsule, right parietal lobe white matter, left lentiform nucleus, left posterior crus of the internal capsule-thalamus, right thalamus, right lateral ventricular pericornu and left paramedian pons. The patient underwent cerebral digital substraction angiography (DSA), as well as IAT, MT, balloon angioplasty, and carotid stenting with good clinical outcome.\u0000Conclusion: With the overwhelming positive results of studies evaluating the safety, efficiency, and efficacy of mechanical thrombectomy; the standard of care for the treatment of patients with anterior circulation vessel occlusion is becoming clear.","PeriodicalId":117574,"journal":{"name":"Medica Hospitalia : Journal of Clinical Medicine","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133313146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analgesic Potency Of Ibuprofen, Paracetamol, And Mephenamic Acid: A Randomized Controlled Trial 布洛芬、扑热息痛和甲苯胺酸的镇痛效力:一项随机对照试验
Medica Hospitalia : Journal of Clinical Medicine Pub Date : 2023-07-31 DOI: 10.36408/mhjcm.v10i2.842
C. R. Nayoan, N. Syamsi
{"title":"Analgesic Potency Of Ibuprofen, Paracetamol, And Mephenamic Acid: A Randomized Controlled Trial","authors":"C. R. Nayoan, N. Syamsi","doi":"10.36408/mhjcm.v10i2.842","DOIUrl":"https://doi.org/10.36408/mhjcm.v10i2.842","url":null,"abstract":"BACKGROUND: Analgesics are a group of drugs to relieve pain. The use of analgesics is quite high, around 22.8% is used per year. Selection of analgesic drugs having adequate potency and minimal side effects is needed. Common analgesics publicly known involve paracetamol 500 mg, mefenamic acid 500 mg, and ibuprofen 400 mg. This study aims to compare the analgesic potency of paracetamol 600 mg, ibuprofen 600 mg and mefenamic acid 500 mg.\u0000METHODS: This study used a double blind randomized control trial. The study population was healthy subjects. The study sample consisted of 30 subjects with the inclusion criteria involve normal vital signs, while the exclusion criteria involve history of allergy to NSAID class drugs. This study consisted of three  groups namely group 1 (K1)= paracetamol 600 mg, group 2 (K2)= mefenamic acid 500 mg, group 3 (K3)= ibuprofen 600 mg. Each subject was given medication according to the group and their pain latency (the time of onset of constant and unbearable pain) was measured every 30 minutes\u0000RESULTS: The repeated ANOVA test shows P= 0.1507 meaning that no significantly different analgesic potency  was found between groups.\u0000CONCLUSION: Paracetamol 600 mg, mefenamic acid 500 mg and ibuprofen 600 mg have equal analgesic potency.","PeriodicalId":117574,"journal":{"name":"Medica Hospitalia : Journal of Clinical Medicine","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116754435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信