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Epilepsy Currents最新文献

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Epilepsy in Alzheimer's Disease: Seizing the Asymmetry in Amyloid, Tau, and Neurodegenerative Pathology. 阿尔茨海默病中的癫痫：抓住淀粉样蛋白、Tau蛋白和神经退行性病理的不对称性。
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-03-02 eCollection Date: 2025-05-01 DOI: 10.1177/15357597251317851
Ifrah Zawar
{"title":"Epilepsy in Alzheimer's Disease: Seizing the Asymmetry in Amyloid, Tau, and Neurodegenerative Pathology.","authors":"Ifrah Zawar","doi":"10.1177/15357597251317851","DOIUrl":"10.1177/15357597251317851","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"167-169"},"PeriodicalIF":5.8,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11873835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inclusivity in Epilepsy Care: Navigating the Complex Nature of Seizure Disorders in People Undergoing Gender-Affirming Care. 癫痫护理的包容性：在接受性别确认护理的人群中导航癫痫疾病的复杂性质。
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-03-02 eCollection Date: 2025-07-01 DOI: 10.1177/15357597251317908
Sasha Alick-Lindstrom, Mindl M Weingarten, Jessica J Falco-Walter, Barry E Gidal, Jessica Abramowitz, Chadrick E Lane, Z Paige L'Erario, Gwen Zeigler, Wesley T Kerr
{"title":"Inclusivity in Epilepsy Care: Navigating the Complex Nature of Seizure Disorders in People Undergoing Gender-Affirming Care.","authors":"Sasha Alick-Lindstrom, Mindl M Weingarten, Jessica J Falco-Walter, Barry E Gidal, Jessica Abramowitz, Chadrick E Lane, Z Paige L'Erario, Gwen Zeigler, Wesley T Kerr","doi":"10.1177/15357597251317908","DOIUrl":"10.1177/15357597251317908","url":null,"abstract":"<p><p>There is a paucity of information to rely on when caring for transgender and gender diverse (TGD) individuals with epilepsy. Clinicians must be aware of the mechanisms of antiseizure medications, potential unique side effects, and medication interactions that require monitoring. This principle is central to the clinical care of the TGD population, specifically for those pursuing gender-affirming care via hormone treatment and/or surgical interventions. This resource aims to support the delivery of quality healthcare with a comprehensive approach for TGD individuals living with epilepsy. This article discusses diverse topics, including antiseizure medications, drug-drug interactions, surgical and neuromodulation techniques, as well as general considerations for managing complex cases of medication-resistant epilepsy in TGD individuals. It also aims to make neurologists familiar with the basics of medical and surgical care for the same population and highlight potential reciprocal effects between comprehensive gender-affirming and epilepsy care.</p>","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"253-262"},"PeriodicalIF":5.8,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11873854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"Worldwide Heterogeneity in Stereo-EEG Theory and Practice: Do all Roads Lead to Rome?" 立体脑电图理论与实践的世界性异质性：条条大路通罗马吗？
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-03-02 eCollection Date: 2025-05-01 DOI: 10.1177/15357597251318541
Ioannis Karakis
{"title":"\"Worldwide Heterogeneity in Stereo-EEG Theory and Practice: Do all Roads Lead to Rome?\"","authors":"Ioannis Karakis","doi":"10.1177/15357597251318541","DOIUrl":"10.1177/15357597251318541","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"161-163"},"PeriodicalIF":5.8,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11873860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Driving Into the Unknown: ASM Reductions After Intracranial EEG. 进入未知：颅内脑电图后ASM减少。
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-02-28 eCollection Date: 2025-03-01 DOI: 10.1177/15357597241311149
Samuel Lapalme-Remis
{"title":"Driving Into the Unknown: ASM Reductions After Intracranial EEG.","authors":"Samuel Lapalme-Remis","doi":"10.1177/15357597241311149","DOIUrl":"10.1177/15357597241311149","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"107-109"},"PeriodicalIF":5.8,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Review of Seizure and Cognitive Outcomes in Resective, Ablative, and Neuromodulatory Temporal Lobe Epilepsy Surgery. 切除、消融和神经调节性颞叶癫痫手术中癫痫发作和认知结局的比较回顾。
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-02-28 DOI: 10.1177/15357597251318564
Chengyuan Wu, Robyn M Busch, Daniel L Drane, Patricia Dugan, Demitre Serletis, Brett Youngerman, Lara Jehi
{"title":"Comparative Review of Seizure and Cognitive Outcomes in Resective, Ablative, and Neuromodulatory Temporal Lobe Epilepsy Surgery.","authors":"Chengyuan Wu, Robyn M Busch, Daniel L Drane, Patricia Dugan, Demitre Serletis, Brett Youngerman, Lara Jehi","doi":"10.1177/15357597251318564","DOIUrl":"https://doi.org/10.1177/15357597251318564","url":null,"abstract":"<p><p>Resective surgery for drug-resistant temporal lobe epilepsy remains underutilized in the United States. While anteromesial temporal lobectomy consistently achieves the highest rates of long-term seizure freedom, it comes with greater risks for memory and language decline. Magnetic resonance imaging-guided laser interstitial thermal therapy and neuromodulation have gained popularity due to perceived lower surgical risk and faster recovery, although they yield lower rates of sustained seizure freedom. Neuromodulation with vagus nerve, deep brain, or responsive neurostimulation provides an option for patients ineligible for resection or ablation, but overall seizure outcomes remain modest. Balancing improved seizure control with open resection against the potential cognitive advantages of less invasive treatments is complex, requiring careful patient selection. Future research must refine these approaches to optimize results. Thoughtful, individualized decision-making, guided by each patient's clinical scenario and goals, is paramount for achieving the best balance between seizure freedom, cognitive preservation, and overall patient outcome.</p>","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"15357597251318564"},"PeriodicalIF":5.8,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychosocial Burden and Suicidality in Epilepsy: A Public Health Concern. 癫痫的心理社会负担和自杀倾向：一个公共卫生问题
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-02-28 eCollection Date: 2025-05-01 DOI: 10.1177/15357597251318577
Elaine T Kiriakopoulos, Felicia Chu, Jay Salpekar, Gaston Baslet, Gena Ghearing, Hamada Altalib, Martha Sajatovic
{"title":"Psychosocial Burden and Suicidality in Epilepsy: A Public Health Concern.","authors":"Elaine T Kiriakopoulos, Felicia Chu, Jay Salpekar, Gaston Baslet, Gena Ghearing, Hamada Altalib, Martha Sajatovic","doi":"10.1177/15357597251318577","DOIUrl":"10.1177/15357597251318577","url":null,"abstract":"<p><p>The increased risk for psychosocial burden and suicidality in people with epilepsy compared to the general population is a well-established global public health concern. Suicidality risk is also increased in patients with functional seizures. The timely identification of patients at highest risk for psychosocial burden and self-harm is vital. This can pose a significant challenge for multidisciplinary clinicians caring for people with epilepsy. Early identification of social stressors and comorbid psychiatric contributors via screening are required to assist with the development of predictive models for self-harm in epilepsy; and subsequent options for treatment and the provision of adjunct supports in the community may help lead to evidence-based suicide prevention strategies for people with epilepsy. Too often, pervasive and common social stressors leading to self-harm go unrecognized and undertreated. Elevating clinician awareness of patient subpopulations at highest risk for suicide, and informing on the advent of evidence-based self-management programs targeting depression and self-harm presents an opportunity to increase suicide prevention in epilepsy.</p>","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"214-220"},"PeriodicalIF":5.8,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869224/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From General Anesthetic to Designer Antiepileptic: Propofol's Mechanism of Action Reveals Hope for Precision Treatment of HCN1-Related Epilepsy. 从全麻到设计抗癫痫药：异丙酚的作用机制为hcn1相关癫痫的精准治疗带来希望。
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-02-28 eCollection Date: 2025-05-01 DOI: 10.1177/15357597251318573
Edward Glasscock
{"title":"From General Anesthetic to Designer Antiepileptic: Propofol's Mechanism of Action Reveals Hope for Precision Treatment of HCN1-Related Epilepsy.","authors":"Edward Glasscock","doi":"10.1177/15357597251318573","DOIUrl":"10.1177/15357597251318573","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"192-194"},"PeriodicalIF":5.8,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cognitive Problems: Epilepsy's Hidden Challenge. 认知问题：癫痫的隐藏挑战。
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-02-02 eCollection Date: 2025-01-01 DOI: 10.1177/15357597241290687
Gewalin Aungaroon
{"title":"Cognitive Problems: Epilepsy's Hidden Challenge.","authors":"Gewalin Aungaroon","doi":"10.1177/15357597241290687","DOIUrl":"10.1177/15357597241290687","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"17-19"},"PeriodicalIF":5.8,"publicationDate":"2025-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11789038/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic Networks of Drug Resistance in Epilepsy: Outputs of a Computational and Translational Disease Framework. 癫痫耐药的遗传网络：计算和转化疾病框架的输出。
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-01-31 eCollection Date: 2025-03-01 DOI: 10.1177/15357597241311113
Eliane Kobayashi
{"title":"Genetic Networks of Drug Resistance in Epilepsy: Outputs of a Computational and Translational Disease Framework.","authors":"Eliane Kobayashi","doi":"10.1177/15357597241311113","DOIUrl":"10.1177/15357597241311113","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"98-100"},"PeriodicalIF":5.8,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Tail Yet to be Told: The Fasciola Cinereum in Epilepsy. 一条尚未被告知的尾巴：癫痫中的电影片形吸虫。
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-01-17 eCollection Date: 2025-03-01 DOI: 10.1177/15357597241309175
Sarah Yaser, Steve C Danzer
{"title":"A Tail Yet to be Told: The Fasciola Cinereum in Epilepsy.","authors":"Sarah Yaser, Steve C Danzer","doi":"10.1177/15357597241309175","DOIUrl":"10.1177/15357597241309175","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"125-127"},"PeriodicalIF":5.8,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143022865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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