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Epilepsy Currents最新文献

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Genetic Testing in Epilepsy: Improving Outcomes and Informing Gaps in Research 癫痫基因检测：提高研究成果，填补研究空白
IF 3.6 2区 医学
Epilepsy Currents Pub Date : 2024-03-25 DOI: 10.1177/15357597241232881
Christa W. Habela, Krista Schatz, Sarah A. Kelley
{"title":"Genetic Testing in Epilepsy: Improving Outcomes and Informing Gaps in Research","authors":"Christa W. Habela, Krista Schatz, Sarah A. Kelley","doi":"10.1177/15357597241232881","DOIUrl":"https://doi.org/10.1177/15357597241232881","url":null,"abstract":"While the diagnosis of epilepsy relies on the presence of seizures, it encompasses a group of phenotypically and etiologically diverse disorders in which seizures may only be one of a constellation of symptoms. There are genetic, structural, and metabolic causes, but most epilepsy syndromes have some genetic predisposition. The importance of genetics in the diagnosis and management of epilepsy has been increasingly recognized over the past 2 decades. With increased access to testing tools and new recommendations that all patients with unexplained epilepsy get genetic testing, it is becoming part of routine clinical care. Increased testing has resulted in an explosion in the number of genes and genetic changes identified and it is changing our understanding of the mechanisms of epileptogenesis. Advances in both clinical genetics and scientific discovery are expanding our potential to impact patient care as well as creating dilemmas. This brief review will highlight where we are regarding our ability to obtain a genetic diagnosis, how diagnoses impact patient care, and the next likely frontiers in diagnosis and management.","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":"30 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140300497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Osteoporosis: The Brittle Reality of an Epilepsy Diagnosis 骨质疏松症：癫痫诊断的脆弱现实
IF 3.6 2区 医学
Epilepsy Currents Pub Date : 2024-03-25 DOI: 10.1177/15357597241238532
Shruti Agashe
{"title":"Osteoporosis: The Brittle Reality of an Epilepsy Diagnosis","authors":"Shruti Agashe","doi":"10.1177/15357597241238532","DOIUrl":"https://doi.org/10.1177/15357597241238532","url":null,"abstract":"[Box: see text]","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":"1 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140300531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Getting Excited About Chloride Cotransporters: Neuroinflammation and Inhibition 令人兴奋的氯化物共转运体：神经炎症与抑制
IF 3.6 2区 医学
Epilepsy Currents Pub Date : 2024-03-25 DOI: 10.1177/15357597241238893
Punam A. Sawant-Pokam, Cameron S. Metcalf
{"title":"Getting Excited About Chloride Cotransporters: Neuroinflammation and Inhibition","authors":"Punam A. Sawant-Pokam, Cameron S. Metcalf","doi":"10.1177/15357597241238893","DOIUrl":"https://doi.org/10.1177/15357597241238893","url":null,"abstract":"[Box: see text]","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":"46 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140300474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapid Whole Genome Sequencing: It Is Feasible! When Can We Implement It? 快速全基因组测序：它是可行的！何时才能实现？
IF 3.6 2区 医学
Epilepsy Currents Pub Date : 2024-03-25 DOI: 10.1177/15357597241237349
Charuta Joshi
{"title":"Rapid Whole Genome Sequencing: It Is Feasible! When Can We Implement It?","authors":"Charuta Joshi","doi":"10.1177/15357597241237349","DOIUrl":"https://doi.org/10.1177/15357597241237349","url":null,"abstract":"[Box: see text]","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":"24 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140301005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Of Hearth and Home: Professional Wellness After Hours 炉灶与家庭：下班后的专业健康
IF 3.6 2区 医学
Epilepsy Currents Pub Date : 2024-03-18 DOI: 10.1177/15357597241237375
Timothy J. Ainger, Meriem Bensalem-Owen, Joanna Fong-Isariyawongse, Matthew William Luedke
{"title":"Of Hearth and Home: Professional Wellness After Hours","authors":"Timothy J. Ainger, Meriem Bensalem-Owen, Joanna Fong-Isariyawongse, Matthew William Luedke","doi":"10.1177/15357597241237375","DOIUrl":"https://doi.org/10.1177/15357597241237375","url":null,"abstract":"Burnout is a prevalent problem in the contemporary practice of medicine. Defined by the Agency for Healthcare Research and Quality as, “a long-term stress reaction marked by emotional exhaustion, depersonalization, and a lack of sense of personal accomplishment,” this multifactorial condition has significant implications for the clinicians who suffer it, their patients, and families. Neurologists suffer some of the highest rates of burnout. Burnout research on interventions often focus on the work environment. In this article, we will focus on burnout’s effects on home life and features of home life that can impact resiliency, specifically sleep hygiene.","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":"143 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140166436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Double, Double Toil and Trouble: Recurrent Episodes of Status Epilepticus Are Associated With Increasingly Worse Outcomes 双倍、双倍的辛劳和麻烦：癫痫状态反复发作与越来越差的预后有关
IF 3.6 2区 医学
Epilepsy Currents Pub Date : 2024-03-18 DOI: 10.1177/15357597231223587
Nicolas Gaspard
{"title":"Double, Double Toil and Trouble: Recurrent Episodes of Status Epilepticus Are Associated With Increasingly Worse Outcomes","authors":"Nicolas Gaspard","doi":"10.1177/15357597231223587","DOIUrl":"https://doi.org/10.1177/15357597231223587","url":null,"abstract":"[Box: see text]","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":"22 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140166468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Step Climb Dosing Guidance From Simulation Studies on Lamotrigine Concentration Changes During Pregnancy 妊娠期拉莫三嗪浓度变化模拟研究的阶梯爬升剂量指南
IF 3.6 2区 医学
Epilepsy Currents Pub Date : 2024-03-12 DOI: 10.1177/15357597241237373
Eliane Kobayashi
{"title":"Step Climb Dosing Guidance From Simulation Studies on Lamotrigine Concentration Changes During Pregnancy","authors":"Eliane Kobayashi","doi":"10.1177/15357597241237373","DOIUrl":"https://doi.org/10.1177/15357597241237373","url":null,"abstract":"[Box: see text]","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":"1 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140127337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Positive Assistance of Assisted Reproductive Technology 辅助生殖技术的积极作用
IF 3.6 2区 医学
Epilepsy Currents Pub Date : 2024-03-05 DOI: 10.1177/15357597241235782
Danielle A. Becker
{"title":"The Positive Assistance of Assisted Reproductive Technology","authors":"Danielle A. Becker","doi":"10.1177/15357597241235782","DOIUrl":"https://doi.org/10.1177/15357597241235782","url":null,"abstract":"[Box: see text]","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":"36 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140044159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sleeping High and Getting Lost on the Spiky Road: What Affects Visual Memory in Older Adults With Epilepsy, and What Can We Do About It? 高枕无忧，迷失在荆棘路上：是什么影响了老年癫痫患者的视觉记忆，我们能做些什么？
IF 3.6 2区 医学
Epilepsy Currents Pub Date : 2024-03-01 DOI: 10.1177/15357597241234246
Rohit Marawar
{"title":"Sleeping High and Getting Lost on the Spiky Road: What Affects Visual Memory in Older Adults With Epilepsy, and What Can We Do About It?","authors":"Rohit Marawar","doi":"10.1177/15357597241234246","DOIUrl":"https://doi.org/10.1177/15357597241234246","url":null,"abstract":"[Box: see text]","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":"47 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140020192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Closing the Loop for Precise Seizure Control 闭合回路，实现精确的缉获控制
IF 3.6 2区 医学
Epilepsy Currents Pub Date : 2024-03-01 DOI: 10.1177/15357597241233221
Bin Gu
{"title":"Closing the Loop for Precise Seizure Control","authors":"Bin Gu","doi":"10.1177/15357597241233221","DOIUrl":"https://doi.org/10.1177/15357597241233221","url":null,"abstract":"[Box: see text]","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":"1 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140018290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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