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Neurodevelopmental Teratogenicity of Antiseizure Medications: The Good, the Bad, and Unknown. 抗癫痫药物的神经发育致畸性：好、坏和未知。
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-03-20 DOI: 10.1177/15357597261434723
Eliane Kobayashi
{"title":"Neurodevelopmental Teratogenicity of Antiseizure Medications: The Good, the Bad, and Unknown.","authors":"Eliane Kobayashi","doi":"10.1177/15357597261434723","DOIUrl":"10.1177/15357597261434723","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"15357597261434723"},"PeriodicalIF":4.6,"publicationDate":"2026-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13004705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147497994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ripples in Time and Space Regulate Epileptic Firing in the Hippocampus. 时空波动调节海马体的癫痫放电。
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-03-16 eCollection Date: 2026-07-01 DOI: 10.1177/15357597261431775
Carl E Stafstrom
{"title":"Ripples in Time and Space Regulate Epileptic Firing in the Hippocampus.","authors":"Carl E Stafstrom","doi":"10.1177/15357597261431775","DOIUrl":"10.1177/15357597261431775","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"325-327"},"PeriodicalIF":4.6,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12992133/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147480095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drugs, Diets, and DEEs: A Comparative Review of Medical and Dietary Treatments in Developmental and Epileptic Encephalopathies. 药物、饮食和饮食：发育性和癫痫性脑病的药物和饮食治疗的比较综述。
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-03-16 eCollection Date: 2026-07-01 DOI: 10.1177/15357597261433562
Chalongchai Phitsanuwong
{"title":"Drugs, Diets, and DEEs: A Comparative Review of Medical and Dietary Treatments in Developmental and Epileptic Encephalopathies.","authors":"Chalongchai Phitsanuwong","doi":"10.1177/15357597261433562","DOIUrl":"10.1177/15357597261433562","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"286-288"},"PeriodicalIF":4.6,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12992124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147479991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cartography of Collapse: Mapping the Architecture of SUDEP. 崩溃制图：绘制SUDEP的体系结构。
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-03-16 eCollection Date: 2026-07-01 DOI: 10.1177/15357597261433268
Ifrah Zawar
{"title":"Cartography of Collapse: Mapping the Architecture of SUDEP.","authors":"Ifrah Zawar","doi":"10.1177/15357597261433268","DOIUrl":"10.1177/15357597261433268","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"310-312"},"PeriodicalIF":4.6,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12992130/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147480029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
National Strategies on Bridging Gaps and Health Equity in Epilepsy Care. 关于缩小癫痫治疗差距和卫生公平的国家战略。
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-03-13 DOI: 10.1177/15357597261428841
Lu Lu, Weixi Xiong, Yicong Lin, Mohamad Z Koubeissi, R Edward Hogan, Dong Zhou
{"title":"National Strategies on Bridging Gaps and Health Equity in Epilepsy Care.","authors":"Lu Lu, Weixi Xiong, Yicong Lin, Mohamad Z Koubeissi, R Edward Hogan, Dong Zhou","doi":"10.1177/15357597261428841","DOIUrl":"10.1177/15357597261428841","url":null,"abstract":"<p><p>Because there are many effective treatments for epileptic seizures, there is a great need for optimal diagnostic and treatment pathways. We present national strategies to address gaps and health equity in patients with epileptic seizures, focusing on efforts in China and the USA. We outline the delay in diagnosis and treatment caused by the \"treatment gap.\" Efforts in China to address the \"treatment gap\" include the National Rural Epilepsy Management Project, the establishment of the national epilepsy quality control system, and standardized tertiary epilepsy center development. In the USA, Project Extension for Community Healthcare Outcomes (ECHO) epilepsy enables specialists to partner with primary care clinicians to deliver care. The National Association of Epilepsy Centers facilitates care and contributes to the standardization of presurgical epilepsy evaluation. A major recent and ongoing development is the Epilepsy National Plan in the USA, coordinated through the American Epilepsy Society (AES) with 120 epilepsy-related organizations, to advance a comprehensive national plan that reflects the needs of the entire epilepsy community.</p>","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"15357597261428841"},"PeriodicalIF":4.6,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12987750/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147467283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementation Science Symposium: Moving the Needle in Epilepsy Care. 实施科学研讨会：在癫痫护理中移动针头。
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-03-13 DOI: 10.1177/15357597261429571
Clio Rubinos, Adam Ostendorf, Daniel Freedman
{"title":"Implementation Science Symposium: Moving the Needle in Epilepsy Care.","authors":"Clio Rubinos, Adam Ostendorf, Daniel Freedman","doi":"10.1177/15357597261429571","DOIUrl":"10.1177/15357597261429571","url":null,"abstract":"<p><p>In order to improve epilepsy care, clinical practice guidelines need to focus on implementation and adoption. This summary of an American Epilepsy Society Annual Meeting symposium on implementation science reviews how this field offers a way to improve guideline utilization and help address knowledge-practice gaps. Historical examples in stroke and sepsis care, as well as present day examples in the treatment of status epilepticus, offer insight into how future guidelines can increase systematic uptake of evidence-based practices. The methodological tools of implementation science can also help address resource limitations and inequitable access to care. Future guideline development should incorporate implementation science practices to ensure the delivery of high-quality epilepsy care.</p>","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"15357597261429571"},"PeriodicalIF":4.6,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12987738/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147467263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in Thalamic Neuromodulation for Epilepsy: From Mechanisms to Clinical Translation. 癫痫丘脑神经调节的研究进展：从机制到临床翻译。
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-03-13 DOI: 10.1177/15357597261430312
Jorge A Gonzalez-Martinez, Arianna Damiani, Joseph Parvizi, Arthur Cukiert, Nick Gregg, Sydney S Cash
{"title":"Advances in Thalamic Neuromodulation for Epilepsy: From Mechanisms to Clinical Translation.","authors":"Jorge A Gonzalez-Martinez, Arianna Damiani, Joseph Parvizi, Arthur Cukiert, Nick Gregg, Sydney S Cash","doi":"10.1177/15357597261430312","DOIUrl":"10.1177/15357597261430312","url":null,"abstract":"<p><p>Thalamic neuromodulation has re-emerged as a central strategy for the treatment of drug-resistant epilepsy, driven by advances in stereo-electroencephalography, network neuroscience, and signal processing. This perspective paper summarizes and integrates the key scientific, technical, and clinical insights presented during the American Epilepsy Society (AES) 2025-Epilepsy Surgery Symposium on <i>Advances in Thalamic Neuromodulation for Epilepsy: From Mechanisms of Action to Clinical Application</i>. Beyond a summary of the individual presentations, this manuscript reflects the collective opinions of the panel regarding current evidence, unresolved controversies, and future directions. An unifying theme emerged: effective thalamic neuromodulation requires a shift from empiric, one-size-fits-all targeting toward patient-specific, hodology-informed strategies grounded in in situ electrophysiology and network-level biomarkers.</p>","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"15357597261430312"},"PeriodicalIF":4.6,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12987745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147467197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Breathing Before Death: Are We Closer to Identifying Premortem Biomarkers of Sudden Unexpected Death in Epilepsy (SUDEP)? 死前呼吸：我们离确定癫痫猝死（SUDEP）的死前生物标志物更近了吗？
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-03-13 eCollection Date: 2026-07-01 DOI: 10.1177/15357597261430045
Vineet Punia
{"title":"Breathing Before Death: Are We Closer to Identifying Premortem Biomarkers of Sudden Unexpected Death in Epilepsy (SUDEP)?","authors":"Vineet Punia","doi":"10.1177/15357597261430045","DOIUrl":"10.1177/15357597261430045","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"283-285"},"PeriodicalIF":4.6,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12987748/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147467223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Automating Critical Care EEG: Enhancing Accuracy, Efficiency, and Patient Outcomes in Critical Care. 危重监护脑电图自动化：提高危重监护的准确性、效率和患者预后。
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-03-13 DOI: 10.1177/15357597261426958
Clio Rubinos, Edilberto Amorim, Erafat Rehim, Andres Rodriguez-Ruiz, Sahar F Zafar, Zubeda B Sheikh, Maria Jose Bruzzone
{"title":"Automating Critical Care EEG: Enhancing Accuracy, Efficiency, and Patient Outcomes in Critical Care.","authors":"Clio Rubinos, Edilberto Amorim, Erafat Rehim, Andres Rodriguez-Ruiz, Sahar F Zafar, Zubeda B Sheikh, Maria Jose Bruzzone","doi":"10.1177/15357597261426958","DOIUrl":"10.1177/15357597261426958","url":null,"abstract":"<p><p>The rapid expansion of continuous EEG (cEEG) monitoring in critically ill patients has created a growing gap between data acquisition and the clinical capacity to interpret these data in a timely manner. This mismatch has emerged alongside major advances in EEG automation, which promise to support more efficient and clinically integrated interpretation. At the same time, evidence guiding the optimal, safe, and ethically responsible use of these tools remains limited. In this review, we trace the historical development of EEG analysis methods from early automation to contemporary AI-based approaches and examine their application in neurocritical care. We discuss the potential benefits and limitations of quantitative EEG and AI for EEG processing, as well as the role of AI in supporting clinical decision-making in these populations when integrated with electronic medical record systems. By focusing on practical implementation and real-world constraints, we aim to show how automated and AI-assisted tools can augment, rather than replace, clinical expertise and help improve the timeliness and quality of patient-centered care.</p>","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"15357597261426958"},"PeriodicalIF":4.6,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12987747/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147467183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microglia on Leave: PLX5622 Reveals Immune Neuronal Crosstalk in Epilepsy and Behavioral Comorbidities. 小胶质细胞休假：PLX5622揭示癫痫和行为合并症中的免疫神经元串扰。
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-03-05 eCollection Date: 2026-05-01 DOI: 10.1177/15357597261427873
Melissa Barker-Haliski
{"title":"Microglia on Leave: PLX5622 Reveals Immune Neuronal Crosstalk in Epilepsy and Behavioral Comorbidities.","authors":"Melissa Barker-Haliski","doi":"10.1177/15357597261427873","DOIUrl":"10.1177/15357597261427873","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"260-262"},"PeriodicalIF":4.6,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12962982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147376372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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