{"title":"Temporary sphincter-preserving covered biliary stent with a frontal umbrella-shaped occlusive mechanism for common bile duct stone removal.","authors":"Wengang Zhang, Hongyi Sun, Qingzhen Wu, Haoqi Zhai, Bozong Shao, Enqiang Linghu","doi":"10.1055/a-2813-3282","DOIUrl":"https://doi.org/10.1055/a-2813-3282","url":null,"abstract":"<p><p>Currently, endoscopic retrograde cholangiopancreatography (ERCP) has been established as standard treatment for common bile duct (CBD) stones. However, this procedure requires endoscopic sphincterotomy (EST), which compromises function of the sphincter of Oddi and may lead to adverse events (AEs) such as bleeding, perforation, biliary reflux of intestinal contents, and stone recurrence. It is particularly unsuitable for patients requiring long-term anticoagulation therapy. In light of this, several researchers, including our team, have attempted to place a self-expandable metal stent (SEMS) in the distal CBD prior to stones clearance as an alternative to EST. Nevertheless, widespread adoption of this strategy has been limited by the issue of stone impaction between the stent and CBD wall. To address this, our team developed a temporary sphincter-preserving covered biliary stent (TSP-CBS) device equipped with a frontal umbrella-shaped occlusive mechanism. The open/close operation of this umbrella component effectively prevents stone impaction as described above. This study first validated safety of TSP-CBS in four porcine models, with no intraoperative or postoperative AEs observed. Subsequently, we performed two clinical cases of EST-free ERCP using TSP-CBS for CBD stone removal. Both procedures successfully cleared the stones. One patient developed postoperative hyperamylasemia, which resolved with conservative management, and no other intraoperative or postoperative AEs occurred. In summary, this preliminary study demonstrates the safety and feasibility of TSP-CBS for performing EST-free ERCP in patients with CBD stones. Further validation in larger clinical cohorts is warranted.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"14 ","pages":"a28133282"},"PeriodicalIF":2.3,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Victor Garbay, Jean-Philippe Ratone, Cristophe Zemmour, Solene Hoibian, Yanis Dahel, Anais Palen, Jonathan Garnier, Jacques Ewald, Olivier Turrini, Marc Giovannini, Fabrice Caillol
{"title":"Correction: Management of multicausal iatrogenic bile duct injuries with biliary fistula: Twenty-year experience in a tertiary center.","authors":"Victor Garbay, Jean-Philippe Ratone, Cristophe Zemmour, Solene Hoibian, Yanis Dahel, Anais Palen, Jonathan Garnier, Jacques Ewald, Olivier Turrini, Marc Giovannini, Fabrice Caillol","doi":"10.1055/a-2837-2157","DOIUrl":"https://doi.org/10.1055/a-2837-2157","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1055/a-2788-3182.].</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"14 ","pages":"a28372157"},"PeriodicalIF":2.3,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062677/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Self-assembling peptide hydrogel prevents esophageal stenosis after endoscopic submucosal dissection for esophageal squamous cell carcinoma: Multicenter prospective study.","authors":"Yuji Urabe, Yuichi Hiyama, Naoki Asayama, Yuzuru Tamaru, Yoji Sanomura, Shigeto Yoshida, Shinji Nagata, Yuko Hiraga, Ayako Takamori, Yasushi Orihashi, Toshio Kuwai, Shiro Oka","doi":"10.1055/a-2816-5350","DOIUrl":"https://doi.org/10.1055/a-2816-5350","url":null,"abstract":"<p><strong>Background and study aims: </strong>Self-assembling peptide hydrogel (PuraStat) is a novel self-assembling peptide-based hemostatic agent that forms a transparent hydrogel upon contact with blood or bodily fluids. It has been reported to reduce the number of coagulations required with hemostatic forceps during gastrointestinal endoscopic procedures. In addition to its hemostatic effect, recent studies have suggested that PuraStat promotes wound healing. This study aimed to investigate the efficacy of PuraStat in preventing esophageal stenosis following endoscopic treatment of esophageal squamous cell carcinoma (ESCC).</p><p><strong>Patients and methods: </strong>This was a single-arm, multicenter, prospective study. Patients with esophageal squamous cell carcinoma who underwent endoscopic submucosal dissection and had a post-resection ulcer involving three-quarters or more of the full circumference of the esophagus received PuraStat application twice: once immediately after the procedure and once at second-look endoscopy 2 to 4 days later. The primary endpoint was incidence of esophageal stenosis within 12 weeks after endoscopic submucosal dissection. Secondary endpoints included the number of endoscopic balloon dilation procedures required and incidence of adverse events (AEs) and serious AEs.</p><p><strong>Results: </strong>Twenty patients were enrolled, all of whom received PuraStat application. Incidence of esophageal stenosis within 12 weeks was 20% (4/20). All cases of stenosis resolved with fewer than six endoscopic balloon dilation procedures and no patients developed refractory esophageal stenosis. AEs were observed in four patients; however, all resolved with conservative management.</p><p><strong>Conclusions: </strong>PuraStat application for post-endoscopic submucosal dissection ulcers in patients with ESCC may be useful for preventing esophageal stenosis.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"14 ","pages":"a28165350"},"PeriodicalIF":2.3,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062683/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lea Pueschel, Jennifer Gill, Marie-Louise Witte, Birgit Terjung, Petra Lynen Jansen, Heiner Wedemeyer, Miriam Wiestler, Henrike Lenzen
{"title":"Through the scope, not the ceiling: Gender distribution among endoscopy sessions at the German Visceral Medicine Congress.","authors":"Lea Pueschel, Jennifer Gill, Marie-Louise Witte, Birgit Terjung, Petra Lynen Jansen, Heiner Wedemeyer, Miriam Wiestler, Henrike Lenzen","doi":"10.1055/a-2826-9119","DOIUrl":"https://doi.org/10.1055/a-2826-9119","url":null,"abstract":"<p><strong>Background and study aims: </strong>Despite awareness of the importance of diversity, equity, and inclusion (DEI) in endoscopy, structural impediments persist. Disparities include underrepresentation of women as speakers and chairs at endoscopy congresses.</p><p><strong>Methods: </strong>Data from endoscopy sessions of the annual German Visceral Medicine congresses from 2013 to 2024 were analyzed. Gender ratios of speakers, chairs, leadership, and award recipients were analyzed over 336 sessions using linear regression and the Cochran-Armitage test for trend.</p><p><strong>Results: </strong>A trend analysis over 11 years revealed significant increases in female participation as speakers (r² = 0.628, <i>P</i> = 0.004) and chairpersons (r² = 0.815, <i>P</i> < 0.001). For speakers, the increase was significant in plenary sessions (r² = 0.628, <i>P</i> = 0.004), but not in abstract sessions (r² = 0.154, <i>P</i> = 0.232) or industry symposia (r² = 0.150, <i>P</i> = 0.239). Meanwhile, female chairperson representation increased significantly across all domains: plenary sessions (r² = 0.815, <i>P</i> < 0.001), abstract sessions (r² = 0.663, <i>P</i> = 0.002), and industry symposia (r² = 0.534, <i>P</i> = 0.011). Gender parity was not reached among speakers but among chairpersons in abstract sessions and industry symposia on isolated occasions.</p><p><strong>Conclusions: </strong>In 2019, the German Society of Gastroenterology, Digestive and Metabolic Diseases Board introduced a parity resolution concerning gender balance among congress session chairs. Since then, notable progress towards achieving gender parity has been made, with a positive trend being indicative of effectiveness of current DEI measures. Nevertheless, there remains a significant lack of adequate female representation in endoscopy sessions, particularly among central congress formats and among speakers. To address this imbalance, further measures such as binding quotas, institutional support, and targeted diversity-oriented congress planning are necessary.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"14 ","pages":"a28269119"},"PeriodicalIF":2.3,"publicationDate":"2026-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply to Coelho-Prabhu et al.","authors":"Jonas L Steinhäuser-Meerz, Franz Brinkmann","doi":"10.1055/a-2828-9613","DOIUrl":"https://doi.org/10.1055/a-2828-9613","url":null,"abstract":"","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"14 ","pages":"a28289613"},"PeriodicalIF":2.3,"publicationDate":"2026-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062673/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cadman Leggett, Jeffrey Fetzer, John League, Shounak Majumder, Darrell Pardi, Nayantara Coelho-Prabhu
{"title":"Automated video recording built into routine clinical practice: What does it take?","authors":"Cadman Leggett, Jeffrey Fetzer, John League, Shounak Majumder, Darrell Pardi, Nayantara Coelho-Prabhu","doi":"10.1055/a-2828-9572","DOIUrl":"https://doi.org/10.1055/a-2828-9572","url":null,"abstract":"","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"14 ","pages":"a28289572"},"PeriodicalIF":2.3,"publicationDate":"2026-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oscar Cahyadi, Christian Torres Reyes, Mousa Ayoub, Daniel Quast, Peter Ewald, Alanna Ebigbo
{"title":"Technical & clinical evaluation of a novel slim gastroscope in third-space procedures: Feasibility, subjective workload & system usability assessment.","authors":"Oscar Cahyadi, Christian Torres Reyes, Mousa Ayoub, Daniel Quast, Peter Ewald, Alanna Ebigbo","doi":"10.1055/a-2820-3851","DOIUrl":"https://doi.org/10.1055/a-2820-3851","url":null,"abstract":"<p><strong>Background and study aims: </strong>Third-space endoscopy, including peroral endoscopic myotomy (POEM) and endoscopic submucosal dissection (ESD), has become an established therapeutic option for various gastrointestinal disorders. A newly developed slim therapeutic gastroscope aims to improve maneuverability and provide easier access to the submucosal space and also to enhance ergonomic aspects of tedious therapeutic procedures. The aim of this study (The Slim Scop3 Trial) was to evaluate the subjective workload and usability of the novel slim therapeutic gastroscope during third space procedures. Secondary outcomes included technical and clinical performance as well as adverse events (AEs).</p><p><strong>Patients and methods: </strong>This was a prospective, single-arm, single-center study comprising 30 patients undergoing third-space endoscopy in a high-volume center in Germany. Subjective workload and usability were assessed with the NASA-Task load index (NASA-TLX) and the System Usability Score (SUS), respectively. Clinical outcomes and AEs were recorded prospectively.</p><p><strong>Results: </strong>The slim gastroscope showed a low NASA-TLX and high SUS score, which correlates with a low subjective workload and high usability. POEM showed a tendency toward lower NASA-TLX and higher SUS compared with ESD. For ESD, the en-bloc and curative R0 resection rate was 100%. No device-related AE events occurred.</p><p><strong>Conclusions: </strong>A novel slim gastroscope offers high usability with a low subjective workload for third space procedures. The slim gastroscope has the potential to reduce ergonomic strain on endoscopists during complex therapeutic interventions.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"14 ","pages":"a28203851"},"PeriodicalIF":2.3,"publicationDate":"2026-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cecile Maxime Van De Leur, Leon Mg Moons, Frank Vleggaar, Paul Didden
{"title":"Octreotide for prevention of delayed bleeding after endoscopic mucosal resection for large superficial non-ampullary duodenal tumors.","authors":"Cecile Maxime Van De Leur, Leon Mg Moons, Frank Vleggaar, Paul Didden","doi":"10.1055/a-2798-2041","DOIUrl":"https://doi.org/10.1055/a-2798-2041","url":null,"abstract":"<p><strong>Background and study aims: </strong>Effective strategies to prevent delayed bleeding (DB) following endoscopic mucosal resection (EMR) for large superficial non-ampullary duodenal tumors (SNADTs) remain limited. Octreotide exerts pharmacological effects that may influence hemostasis and thereby reduce bleeding risk. This exploratory study aimed to evaluate the association between postprocedural octreotide use and DB after duodenal EMR for large SNADTs.</p><p><strong>Patients and methods: </strong>This single-center, exploratory, retrospective study included all hot EMRs for large SNADTs ≥ 10 mm (2015-2024). Routine post-procedural intravenous octreotide (50 μg/h) was introduced in 2022, administered immediately post-EMR at 50 μg/hour during overnight observation. DB was defined as clinically significant bleeding within 30 days requiring prolonged hospitalization, readmission, or intervention.</p><p><strong>Results: </strong>A total of 107 SNADTs (median diameter 25 mm; interquartile range 15-40) were resected, including 33 treated with octreotide. Overall, DB occurred in 20% of patients (21/107), including 24% (18/74) in the control group and 9% (3/33) in the octreotide group. In logistic regression adjusting for lesion size and propensity score, octreotide showed a non-significant trend toward reduced DB overall (odds ratio [OR] 0.34; 95% confidence interval [CI] 0.08-1.17; <i>P</i> = 0.11). In the subgroup of lesions ≥ 30 mm, octreotide use was associated with a significantly lower odds of DB (OR 0.21; 95% CI 0.039-0.89; <i>P</i> = 0.045), whereas this association was not observed in smaller lesions.</p><p><strong>Conclusions: </strong>In this exploratory study, postprocedural intravenous octreotide appeared to be associated with a lower occurrence of DB after EMR for large SNADTs (≥ 30 mm). Larger, prospective studies are warranted to confirm these findings.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"14 ","pages":"a27982041"},"PeriodicalIF":2.3,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13063296/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katarzyna M Pawlak, Mateusz Jagielski, Kareem Khalaf, Jacek Piątkowski, Jacek Szeliga, Marek Jackowski
{"title":"Endoscopic ultrasound-guided transgastric drainage of pancreaticopleural fistulas.","authors":"Katarzyna M Pawlak, Mateusz Jagielski, Kareem Khalaf, Jacek Piątkowski, Jacek Szeliga, Marek Jackowski","doi":"10.1055/a-2823-8105","DOIUrl":"https://doi.org/10.1055/a-2823-8105","url":null,"abstract":"<p><strong>Background and study aims: </strong>Pancreaticopleural fistula (PPF) is a rare complication of chronic pancreatitis with prevalence of 0.4%. Drainage under endoscopic ultrasound (EUS) guidance may offer an alternative with unassessed efficacy and safety. This case series aimed to initially assess efficacy and safety of EUS-guided transgastric drainage of PPF.</p><p><strong>Patients and methods: </strong>This was a retrospective case series that analyzed outcomes of EUS-guided drainage in four patients with PPF. The study was carried out at the Department of General, Gastroenterological, and Oncological Surgery, Collegium Medicum, Nicolaus Copernicus University in Torun (Poland), between 2021-2023.</p><p><strong>Results: </strong>PPF was identified in four patients with chronic pancreatitis. Fistula tracts were arising from the body (2/4;50%), tail (1/4; 25%), and neck (1/4; 25%). Mean fistula diameter and length were 26.25 mm (15-50 mm) and 107.5 (80-150 mm), respectively. Due to inefficiency of conservative treatment and transpapillary drainage in endoscopic retrograde cholangiopancreatography (ERCP), EUS-guided transgastric/transmural drainage of the PPF was performed using metal or plastic stents. Technical and clinical success was achieved in all patients with no adverse events (AEs). Mean hospital stay was 7.75 days (5-12 days), and symptoms resolved in all patients. All stents were removed. There was no recurrence during mean follow-up of 603.5 days (93-1236 days).</p><p><strong>Conclusions: </strong>EUS-guided transgastric drainage appears to be a promising alternative for refractory PPF, resulting in technical and clinical success with minimal AEs. Long-term follow-up underscores sustained symptom resolution and absence of recurrence, highlighting its potential in managing this challenging complication.</p>","PeriodicalId":11671,"journal":{"name":"Endoscopy International Open","volume":"14 ","pages":"a28238105"},"PeriodicalIF":2.3,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13063297/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147671442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}