Endocrinology and Metabolic Syndrome最新文献_第4页

Heme oxygenase is an important switch-box that ameliorates cardio-renal complications in diabetes 血红素加氧酶是改善糖尿病心肾并发症的重要开关

Endocrinology and Metabolic Syndrome Pub Date : 2018-10-05 DOI: 10.4172/2161-1017-C2-025

pSermin Kesebirp

引用次数: 0

Radiofrequency ablation for non-functioning benign thyroid nodules in children and adolescent 射频消融治疗儿童和青少年无功能良性甲状腺结节

Endocrinology and Metabolic Syndrome Pub Date : 2018-08-31 DOI: 10.4172/2161-1017-C1-024

P. Hassan, Kiran Rafiqp

引用次数: 0

A Mixture of Glycine and Cinnamon Extract Improves Glucose Uptake and Imparts Favourable Metabolic Changes in Men and Women in Response to an Oral Glucose Load 甘氨酸和肉桂提取物的混合物在口服葡萄糖负荷下改善葡萄糖摄取并赋予男性和女性有利的代谢变化

Endocrinology and Metabolic Syndrome Pub Date : 2018-08-23 DOI: 10.4172/2161-1017.1000289

R. Bloomer, M. Butawan, Judi Quilici Timmcke, B. Qin

{"title":"A Mixture of Glycine and Cinnamon Extract Improves Glucose Uptake and Imparts Favourable Metabolic Changes in Men and Women in Response to an Oral Glucose Load","authors":"R. Bloomer, M. Butawan, Judi Quilici Timmcke, B. Qin","doi":"10.4172/2161-1017.1000289","DOIUrl":"https://doi.org/10.4172/2161-1017.1000289","url":null,"abstract":"Objective: slightly elevated have been independently reported to favorably impact blood glucose. To our knowledge, no study has combined these two ingredients through oral supplementation in an attempt to modify the glycemic response to a glucose load. We determined the impact of acute ingestion of a novel glycine-cinnamon extract mixture on blood glucose, insulin, and related variables following an oral glucose challenge.Methods: Ten men and women (25.4 ± 8.3 yrs) with elevated fasting blood glucose (101.2 ± 6.6 mg•dL-1) ingested a 25 gram glucose beverage with and without SugarClear™, a proprietary blend of glycine+cinnamon extract (as Cinnulin PF®), separated by approximately one week. Blood was collected before and at 20, 60, and 120 minutes post ingestion and analyzed for glucose, insulin, glucagon-like peptide-1 (GLP-1), glucagon, ATP, and brainderived neurotrophic factor (BDNF).Results: Significant reductions in the area under the curve (AUC) were noted for both glucose (15% for total AUC and 52% for net incremental AUC) and insulin (7% for total AUC and 57% for net incremental AUC). The total AUC for GLP-1 was increased by 36%, while the AUC for ATP was increased by 20%. Glucagon was lower by 10% and BDNF higher by 5% with treatment but not in a statistically significant manner (p>0.05).Conclusion: Acute ingestion of SugarClear™, a proprietary blend of glycine and cinnamon extract, promotes a positive impact on blood glucose and insulin following an oral glucose load. The mixture also leads to an increase in both the plasma GLP-1 and ATP. These alterations may have favourable metabolic implications in those with elevated blood glucose. Future work is needed to determine the effect of chronic ingestion of SugarClear™ on glucose regulation and related variables.","PeriodicalId":11670,"journal":{"name":"Endocrinology and Metabolic Syndrome","volume":"57 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2018-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84062808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sirtuins Regulation In Diabetic Condition 糖尿病条件下Sirtuins的调节

Endocrinology and Metabolic Syndrome Pub Date : 2018-05-26 DOI: 10.4172/2161-1017.1000e126

Abhinav Kanwal, A. Thaliath

引用次数: 0

Beneficials Effects of Canagliflozin in a Weight-Centered Management in Patients with Type 2 Diabetes Mellitus in Real Practice 卡格列净在以体重为中心治疗2型糖尿病患者中的有益作用

Endocrinology and Metabolic Syndrome Pub Date : 2018-04-03 DOI: 10.4172/2161-1017.1000286

F. Carral, M. Cayon, Ana Isabel Jiménez, D. Cabo

{"title":"Beneficials Effects of Canagliflozin in a Weight-Centered Management in Patients with Type 2 Diabetes Mellitus in Real Practice","authors":"F. Carral, M. Cayon, Ana Isabel Jiménez, D. Cabo","doi":"10.4172/2161-1017.1000286","DOIUrl":"https://doi.org/10.4172/2161-1017.1000286","url":null,"abstract":"Objective: Evaluate the real-world efficacy and safety of canagliflozin in patients with type 2 diabetes mellitus (T2DM), associated to a weight-loss intensive lifestyle intervention program (WLIP), to achieve weight loss greater than 5% at 12 months.Methods: Retrospective review of patients with T2DM included in a WLIP, who were prescribed canagliflozin from June 2015 to December 2016 at four endocrinology clinics in the south of Spain within routine clinical practice context. Changes during 12 months in anthropometric variables, HbA1c, uric acid and adverse events were assessed.Results: 201 patients with T2DM (45.8% women, 60.3 ± 9.4 years old and BMI: 34.9 ± 8.7 kg/m2) were studied. Patients treated with canagliflozin lost an average weight and reduced an average of waist circumference of -4.0 ± 4.2 kg and -3.2 ± 8.4 cm, -5.4 ± 5.7 kg and -4.9 ± 9.9 cm and -5.3 ± 8.0 kg and -7.0 ± 14.6 cm, achieving weight loss greater than 5%: 29.0%, 47.9% and 42.7% of patients at 3, 6 and 12 months, respectively. HbA1c levels were average reduced by -1.2%, -1.3% and -1.3% and 68.8% reached an HbA1c level ≤ 7% at 12 months. 17.9% (36 patients) experienced mild adverse events and canagliflozin treatment was suspended in 23 patients (11.4%).Conclusion: The addition of canagliflozin to the treatment of overweight or obese patients with T2DM, as a complement of a weight-loss intensive lifestyle intervention, was associated with improvement in body weight and glycemic control with relative mild adverse events.","PeriodicalId":11670,"journal":{"name":"Endocrinology and Metabolic Syndrome","volume":"115 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85932475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Food Pyramid for Low Carbohydrate Diet (LCD) with its Efficacy and Actual Intake 低碳水化合物饮食的食物金字塔及其功效和实际摄入量

Endocrinology and Metabolic Syndrome Pub Date : 2018-03-10 DOI: 10.4172/2161-1017.1000I016

H. Bando, K. Ebe, Takumi Nakamura, Takako Manabe

引用次数: 2

A Case Which Hypoglycemia Might Be Caused Transiently by Performing Transcatheter Arterial Embolization (TAE) for a Traumatic Adrenal Gland Injury 外伤性肾上腺损伤行经导管动脉栓塞术可致短暂性低血糖1例

Endocrinology and Metabolic Syndrome Pub Date : 2018-03-10 DOI: 10.4172/2161-1017.1000i015

K. Shiga, K. Kase, Toshiaki Terauchi, Kenji Kobayashi, Shigeatu Endo

引用次数: 0

Unique Therapeutic Approach of Tab.Dibet-All (A Poly Herbomineral Formulation), Tab.Dtox-OD and Tab.Glybra in a Newly Diagnosed Case of Type-2 Diabetes Mellitus. A Case Report Tab独特的治疗方法。dibeti - all (A Poly herbommineral Formulation)， Tab。Dtox-OD和Tab。1例新诊断的2型糖尿病的Glybra。病例报告

Endocrinology and Metabolic Syndrome Pub Date : 2018-03-02 DOI: 10.4172/2161-1017.1000285

D. Giri

{"title":"Unique Therapeutic Approach of Tab.Dibet-All (A Poly Herbomineral Formulation), Tab.Dtox-OD and Tab.Glybra in a Newly Diagnosed Case of Type-2 Diabetes Mellitus. A Case Report","authors":"D. Giri","doi":"10.4172/2161-1017.1000285","DOIUrl":"https://doi.org/10.4172/2161-1017.1000285","url":null,"abstract":"Along with all the commonly known rationale; oxidative stress, reactive oxygen species (ROS), growing number of AGEs, accumulation and outbreak of Tridoshas. Throughout year plays decisive role in the development of Diabetes as well as its complications. In the present study, I have discussed about their effective and economical management based on the principles of Ayurveda in the form of distinctive line of treatment which includes Tab.Dibet-all (a poly herbomineral formulation), Tab. Dtox-OD and Tab Glybra. This trio is indistinguishable from allopathy drugs in terms of pharmacology. With so many benefits concealed inside; this line of treatment is having remarkable potential regarding antidibetic, antiglycating, antihyperlipidimic, rejuvinative and preventive/protective activities by the means of breaking cross-links of proteins induced by AGEs, inhibition of AGE formation, blockade of the AGE–RAGE interaction, suppression of RAGE expression and prevention from glycer-AGEs-induced ROS formation ensuring good control over intricate pathology of diabetes and thus protecting diabetics to a higher extent from the complications of diabetes slowly footing towards them. This is the most imperative thing regarding intricate and vague pathology like Diabetes mellitus. \u0000Only the integrated approach towards this gruesome situation will going to help mankind. May this study of ‘Tab. Dibet-all (a poly herbomineral formulation), Tab. Dtox-OD and Tab. Glybra’ with its sovereign effects could serve as a light of hope towards search of ideal treatment of Diabetes mellitus type-2. This can be a supplementary remedy for type-1, hereditary and chronic diabetics also and unquestionably lend a hand to revolutionize the future scenario of these tribulations.","PeriodicalId":11670,"journal":{"name":"Endocrinology and Metabolic Syndrome","volume":"118 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2018-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89609959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current Risk Factors of Ischemic Cardiovascular Diseases Estimated in a Representative Population of Casablanca 卡萨布兰卡代表性人群缺血性心血管疾病的当前危险因素评估

Endocrinology and Metabolic Syndrome Pub Date : 2018-03-02 DOI: 10.4172/2161-1017.1000284

K. Mohtadi, Rajaa Msaad, Rajaa Essadik, H. Lebrazi, A. Kettani, H. Taki, R. Saile

{"title":"Current Risk Factors of Ischemic Cardiovascular Diseases Estimated in a Representative Population of Casablanca","authors":"K. Mohtadi, Rajaa Msaad, Rajaa Essadik, H. Lebrazi, A. Kettani, H. Taki, R. Saile","doi":"10.4172/2161-1017.1000284","DOIUrl":"https://doi.org/10.4172/2161-1017.1000284","url":null,"abstract":"Background: Cardiovascular diseases have been the leading cause for mortality in the last decades. Controlling the modifiable cardiovascular risk factors may reduce mortality due to them. In this context, we tried to identify some of these cardiovascular risk factors in representative population of Casablanca.Methods: Our study concerned 609 subjects (363 women and 246 men) that were aged from 18 to 65 years old. The analyses were based on data from a lifestyle questionnaire with sociodemographic characteristics, medical history and lifestyle factors such as physical activity and smoking. We also assessed Anthropometric measurements and biochemical. Then, our population was subdivided into 3 groups according to their Body Mass Index: Obese, overweight and a normal group.Results: The analysis showed that the mean-age was 54.47 ± 10.89 years old and 59.86% were female. The prevalence of diabetes and hypertension were respectively 38.1% and 35.8% with a dominance of women. The highest atherogenic index of plasma (AIP) was observed in overweight and obese groups with 31.1%, 28.2% respectively. The prevalence of hypercholesterolemia was 7.1 %. We notice that 35.20%, 13.98% and 1.81% have respectively 3 ,4 and 5 Cardiovascular disease risk factors whereas 5.26% have none, we observed too that women have more (59.7% vs. 40.3%).Conclusion: There is a high prevalence of cardiovascular risk factors in the general population of Casablanca, which is due to unhealthy habits like sedentary life style, Diabetes and/or Hypertension.","PeriodicalId":11670,"journal":{"name":"Endocrinology and Metabolic Syndrome","volume":"24 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80887252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Serum-anti Mullerian hormone (AMH): A proposal into rethinking how we diagnose PCOS globally 血清抗苗勒管激素(AMH):重新思考全球多囊卵巢综合征诊断的建议

Endocrinology and Metabolic Syndrome Pub Date : 2018-01-04 DOI: 10.4172/2161-1017-C1-021

Jennifer E Plouffe

引用次数: 0