Endocrine最新文献

{"title":"Ethnic differences in pregnancies complicated by gestational diabetes mellitus: a multiethnic cohort study.","authors":"Kleoniki I Athanasiadou, Georgios Markozannes, Fotini Kanouta, Marina Mitropoulou, Panagiotis Antsaklis, Kalliopi Pappa, Theodora Psaltopoulou, George Daskalakis, Dimitrios G Goulis, Vasiliki Vasileiou, Stavroula A Paschou","doi":"10.1007/s12020-026-04624-5","DOIUrl":"https://doi.org/10.1007/s12020-026-04624-5","url":null,"abstract":"","PeriodicalId":11572,"journal":{"name":"Endocrine","volume":"91 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13139220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147835206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of life and associated factors among children with type 1 diabetes in paediatric tertiary care hospitals in khartoum state, sudan: a cross-sectional study.","authors":"Tebyan Abdalgader Abdallah Mohammed Ali, Moez Salah Babiker Mohammed, Hafeia A Abdelqyoum, Mohammed Abdalla Babiker Abdalla, Shamsaldeen Yusuf Mustafa Ahmed, Ahmed Hussein, Marfa Abdullah Mohamed Ali, Eyas Ahmed Yousif Mohammedalamin, Ghofran Salahelden, Ahmed Mohamed, Danya Ibrahim, Kamil Mirghani Shaaban","doi":"10.1007/s12020-026-04653-0","DOIUrl":"https://doi.org/10.1007/s12020-026-04653-0","url":null,"abstract":"","PeriodicalId":11572,"journal":{"name":"Endocrine","volume":"91 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147812336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical value of multi-time-point ⁶⁸Ga-Pentixafor PET/CT imaging in the subtype diagnosis of primary aldosteronism.","authors":"Tingting Xu, Peng Wang, Tengfei Li, Xinyao Yu, Ke Cheng, Yan Zhu, Yue Chen","doi":"10.1007/s12020-026-04649-w","DOIUrl":"https://doi.org/10.1007/s12020-026-04649-w","url":null,"abstract":"","PeriodicalId":11572,"journal":{"name":"Endocrine","volume":"91 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147812517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tumor size and vascular and perineural invasion predict mesenteric involvement in small-intestinal neuroendocrine tumors.","authors":"Murad Ali, Alessandro Gambella, Alessandro Vanoli, Chandra Bortolotto, Edoardo D'Este, Filippo Checchin, Manuela Albertelli, Diego Ferone, Virginia Sambuceti, Giuseppe Cittadini, Atta Ur Rehman, Federica Grillo","doi":"10.1007/s12020-026-04636-1","DOIUrl":"https://doi.org/10.1007/s12020-026-04636-1","url":null,"abstract":"","PeriodicalId":11572,"journal":{"name":"Endocrine","volume":"91 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147812392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circulating plasma/serum microRNAs in Type 2 Diabetes Mellitus and Its Complications: A Systematic Review and Meta-Analysis of Diagnostic Test Accuracy.","authors":"Umer Adnan, Fizzah Haroon, Syeda Samnita Batool Zaidi, Syeda Sadia Fatima","doi":"10.1007/s12020-026-04641-4","DOIUrl":"https://doi.org/10.1007/s12020-026-04641-4","url":null,"abstract":"","PeriodicalId":11572,"journal":{"name":"Endocrine","volume":"91 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147812513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetic ketoacidosis in end-stage renal disease: propensity score-matched national inpatient outcomes.","authors":"Nida Anwaar, Mohammed A Quazi, David A Baron Herrera, Humza Saeed, Raja Ravender, Eyad Mando-Dakkak, Abu Baker Sheikh","doi":"10.1007/s12020-026-04647-y","DOIUrl":"https://doi.org/10.1007/s12020-026-04647-y","url":null,"abstract":"<p><strong>Background: </strong>Diabetic ketoacidosis (DKA) increasingly occurs in patients with end-stage renal disease (ESRD), in whom standard management strategies may not be appropriate. Prior studies evaluating outcomes of DKA in ESRD are limited and yield inconsistent results. We compared in-hospital outcomes and healthcare utilization among patients hospitalized with DKA with and without ESRD using a national database.</p><p><strong>Methods: </strong>We performed a retrospective cohort study using the National Inpatient Sample (2016-2022) of adult hospitalizations with a primary diagnosis of DKA, comparing patients with and without ESRD. Propensity score matching was used to balance demographics and comorbidities; multivariable regression was used to estimate adjusted odds ratios (aORs) for in-hospital mortality, major in-hospital complications, length of stay, and inflation-adjusted hospitalization costs.</p><p><strong>Results: </strong>After propensity score matching, 78,470 hospitalizations were included (39,235 with ESRD and 39,235 without ESRD). In-hospital mortality was similar between patients with and without ESRD (0.9% vs. 1.0%; aOR 0.90, 95% CI 0.65-1.24; p = 0.524). However, ESRD was associated with significantly higher odds of vasopressor use (aOR 1.56), invasive mechanical ventilation (aOR 1.74), non-invasive ventilation (aOR 1.62), septic shock (aOR 1.71), seizures (aOR 1.67), and sudden cardiac arrest (aOR 1.65) (all p < 0.05). ESRD was also associated with longer hospital length of stay (+ 1.42 days) and higher inflation-adjusted hospitalization costs (+$24,686) compared with matched non-ESRD patients.</p><p><strong>Conclusions: </strong>Among patients hospitalized with DKA, ESRD was not associated with increased in-hospital mortality after adjustment but was linked to substantially greater morbidity and healthcare resource utilization. These findings highlight the need for ESRD-adapted DKA management strategies aimed at reducing complications rather than mortality alone.</p>","PeriodicalId":11572,"journal":{"name":"Endocrine","volume":"91 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147812570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of MRI-based vertebral bone quality scoring and its integration with BMD for identifying fragility fractures in postmenopausal women with type 2 diabetes mellitus.","authors":"Bo Yuan, Xiaobo Zhang, Hengfen Hu","doi":"10.1007/s12020-026-04654-z","DOIUrl":"https://doi.org/10.1007/s12020-026-04654-z","url":null,"abstract":"","PeriodicalId":11572,"journal":{"name":"Endocrine","volume":"91 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147812605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From disease heterogeneity to precision therapy in type 1 diabetes mellitus.","authors":"Laura Nigi, Raffaella Pagano, Francesca Sarti, Guido Sebastiani, Francesco Dotta","doi":"10.1007/s12020-026-04637-0","DOIUrl":"https://doi.org/10.1007/s12020-026-04637-0","url":null,"abstract":"","PeriodicalId":11572,"journal":{"name":"Endocrine","volume":"91 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of persistent and recurrent Cushing's disease: Efficacy of repeat transsphenoidal surgery.","authors":"Isabella Nasi-Kordhishti, Hanna Gött, Lucas Moritz Wiggenhauser, Jürgen Honegger","doi":"10.1007/s12020-026-04638-z","DOIUrl":"https://doi.org/10.1007/s12020-026-04638-z","url":null,"abstract":"<p><strong>Purpose: </strong>Transsphenoidal surgery (TSS) is the treatment of choice for Cushing's disease (CD). In experienced pituitary centers a high remission rate is reported. Nevertheless, endocrinologists and neurosurgeons face cases with persistent or recurrent CD. In addition to medical treatment, radiation therapy and bilateral adrenalectomy, repeat TSS must also be considered. This study evaluates outcomes and predictors of remission following repeat TSS in patients with CD.</p><p><strong>Methods: </strong>A retrospective single-center analysis was conducted including all patients who underwent re-TSS for persistent (n = 29) or recurrent (n = 42) CD between 2004 and 2024. Clinical, radiological, intraoperative, and biochemical data were analyzed for factors influencing remission and long-term outcome.</p><p><strong>Results: </strong>Remission was achieved in 75.4% at first follow-up and 55.7% at long-term follow-up; early/long-term remission was 70.8%/50.0% after surgery for persistence and 78.4%/59.5% after surgery for recurrence. First reoperation yielded higher remission than those with ≥ 2 prior surgeries (81.6% vs. 50.0%, p = 0.030). Invasive tumor growth was strongly associated with reduced remission (p = 0.001). Selective adenomectomy or adenomectomy with rim excision achieved the highest early remission, whereas subtotal or purely explorative resections were less effective (p = 0.011), indicating that targeted resection of an identifiable lesion improves outcome. Postoperative complications occurred in 14.1% (10/71); major complications in 8.5% (6/71); there was no perioperative mortality.</p><p><strong>Conclusion: </strong>Repeat TSS is a safe and effective treatment for both persistent and recurrent CD in specialized pituitary centers. Surgical success depends on tumor invasiveness, prior operations, and surgical strategies. Reoperation should be considered an essential part of individualized, multidisciplinary management to achieve sustained remission.</p>","PeriodicalId":11572,"journal":{"name":"Endocrine","volume":"91 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147812316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Once-weekly somapacitan vs. daily norditropin in GHD: a systematic review and meta-analysis of efficacy and safety in children and adults.","authors":"Sarah Azhar, Mohammad Daniyal, Roshni Riaz Memon, Hamza Sajid, Nad E Ali Yousfani, Hamza Yousuf Ibrahim, Syeda Umme Farwa, Shaharyar Ahmed, Mohsin Ali, Rimsha Abbas, Syed Muhammad Abbas, Ahmed Ali Khan, Haider Imran","doi":"10.1007/s12020-026-04640-5","DOIUrl":"https://doi.org/10.1007/s12020-026-04640-5","url":null,"abstract":"","PeriodicalId":11572,"journal":{"name":"Endocrine","volume":"91 1","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147812381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}