Nu Zhang, Zhiyu Wu, Mengyuan Luo, Zhihua Mi, Qiqing Shi
{"title":"Association of Serum Lactate Dehydrogenase With Sepsis-Associated Acute Kidney Injury: A Large-Scale Analysis Based on the MIMIC-IV Database.","authors":"Nu Zhang, Zhiyu Wu, Mengyuan Luo, Zhihua Mi, Qiqing Shi","doi":"10.1155/emmi/9179449","DOIUrl":"10.1155/emmi/9179449","url":null,"abstract":"<p><strong>Background: </strong>Sepsis-associated acute kidney injury (SA-AKI) frequently occurs during critical illness and represents a serious complication of sepsis. Although serum lactate dehydrogenase (LDH) may reflect tissue injury and metabolic derangement, large-cohort evidence relating LDH to SA-AKI remains limited.</p><p><strong>Methods: </strong>We analyzed a retrospective cohort of adults with sepsis identified in Medical Information Mart for Intensive Care IV (MIMIC-IV). The exposure was serum LDH recorded during the first 24 h after ICU admission, grouped by quartile. Associations with SA-AKI were estimated using logistic regression models with stepwise covariate adjustment for demographics, comorbid disease, illness severity, and selected metabolic and inflammatory laboratory variables. Restricted cubic splines were fitted to assess possible nonlinearity.</p><p><strong>Results: </strong>The final cohort comprised 9461 patients. The incidence of SA-AKI increased from 44.2% in the lowest LDH quartile to 70.6% in the highest quartile (<i>p</i> < 0.001). In the expanded model including demographics, comorbidities, illness severity, lactate, white blood cell count, and glucose, higher LDH levels retained a statistically significant association with SA-AKI (adjusted OR: 1.033 per 100 U/L, 95% CI: 1.025-1.042, <i>p</i> < 0.001). Spline modeling indicated nonlinearity, with the curve becoming steeper in the higher LDH range.</p><p><strong>Conclusion: </strong>In this MIMIC-IV cohort, LDH values obtained during the first 24 h after ICU admission were positively associated with SA-AKI. Because the analysis was observational, the results should be viewed as associative rather than causal.</p>","PeriodicalId":11528,"journal":{"name":"Emergency Medicine International","volume":"2026 ","pages":"9179449"},"PeriodicalIF":1.6,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13501253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148812175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Contrast-Enhanced CT Brain on Renal Function in Potential Intraarterial Therapy Patients in the Emergency Department.","authors":"Cheuk Ki Chan, Chi Li, Ping Chung Gordon Lee","doi":"10.1155/emmi/9010553","DOIUrl":"10.1155/emmi/9010553","url":null,"abstract":"<p><strong>Introduction: </strong>Timely imaging is the cornerstone of hyperacute stroke management in emergency departments (EDs). However, the potential nephrotoxicity of iodinated contrast media remains a significant concern for clinicians when considering potential candidates for intraarterial therapy (IAT). This study aimed to investigate the effect of contrast-enhanced computed tomography (CT) on renal function among potential IAT candidates in a local ED.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study of 112 patients at an ED in Hong Kong who underwent contrast-enhanced CT brain for IAT eligibility screening. Renal function was assessed via serum creatinine and estimated glomerular filtration rate (eGFR) at baseline and postprocedure. Subgroup analyses were performed to evaluate the impact of age, preexisting chronic kidney disease (CKD; eGFR < 60 mL/min/1.73 m<sup>2</sup>), diabetes mellitus (DM), hypertension (HT), and medications on postcontrast renal outcomes. The primary outcome was the incidence of postcontrast acute kidney injury (PC-AKI), defined according to the Kidney Disease: Improving Global Outcomes (KDIGO) criteria.</p><p><strong>Results: </strong>The overall incidence of PC-AKI was low at 0.89% (<i>n</i> = 1). Postcontrast analysis revealed an overall statistically significant reduction in mean serum creatinine from 104.97 to 90.26 μmol/L (<i>p</i> = 0.011), corresponding to an improvement in mean eGFR from 70.20 to 75.13 mL/min/1.73 m<sup>2</sup> (<i>p</i> < 0.001). Within the CKD subgroup (<i>n</i> = 27), mean eGFR increased by 8.67 mL/min/1.73 m<sup>2</sup> (95% CI 3.71, 13.63) (<i>p</i> = 0.001). Due to the low incidence, the study was underpowered to identify risk factors for PC-AKI, and multivariable regression was not feasible.</p><p><strong>Conclusions: </strong>Contrast-enhanced CT brain for the workup of potential IAT patients was not associated with clinically evident renal deterioration in this single-centered retrospective cohort. Prospective studies with larger sample sizes, standardized timing for blood tests, and systematic assessment of confounders are required to confirm these findings.</p>","PeriodicalId":11528,"journal":{"name":"Emergency Medicine International","volume":"2026 ","pages":"9010553"},"PeriodicalIF":1.6,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13501162/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148812229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to \"Characteristics of Wellens' Syndrome in the Current PCI Era: A Single-Center Retrospective Study\".","authors":"","doi":"10.1155/emmi/9838150","DOIUrl":"https://doi.org/10.1155/emmi/9838150","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1155/2023/8865553.].</p>","PeriodicalId":11528,"journal":{"name":"Emergency Medicine International","volume":"2026 ","pages":"9838150"},"PeriodicalIF":1.6,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13490703/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148789641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lin Lan, Min Dai, Yilong Chen, Hao Zhang, Luying Zhong, Shan Tang, Xiaoli Chen
{"title":"Machine Learning Models for Identifying Factors Associated With Workplace Violence Among Emergency Nurses: A Comparative Study.","authors":"Lin Lan, Min Dai, Yilong Chen, Hao Zhang, Luying Zhong, Shan Tang, Xiaoli Chen","doi":"10.1155/emmi/9275645","DOIUrl":"10.1155/emmi/9275645","url":null,"abstract":"<p><strong>Objective: </strong>To develop and compare three machine learning models for identifying factors associated with workplace violence (WPV) among emergency department nurses.</p><p><strong>Methods: </strong>A total of 1540 emergency department nurses from various regions of China were examined between December 2023 and January 2024. Data were collected using scales measuring WPV, work-family conflict, occupational stress, occupational burnout, nursing practice environment, and self-rated sleep quality. Three analytical models (logistic regression, decision tree, and random forest) were developed and compared to classify nurses with and without WPV experiences among emergency department nurses. Model performance was evaluated using sensitivity, specificity, PPV, NPV, F1-score, balanced accuracy, and area under the receiver operating characteristic curve (AUC).</p><p><strong>Results: </strong>Among the 1540 nurses, 1309 individuals (85.0%) had experienced WPV in the past year. All three models indicated that work-family conflict, occupational burnout, and occupational stress were significantly associated with WPV experiences among emergency department nurses (<i>p</i> < 0.05). In the random forest and decision tree models, sleep disorders and the nursing practice environment were also identified as significant associated factors. The accuracy of the logistic regression, decision tree, and random forest models was 0.829, 0.851, and 0.859; the specificity was 0.667, 0.605, and 0.593; the sensitivity was 0.864, 0.903, and 0.916; and the F1 score was 0.893, 0.909, and 0.915, respectively, with AUC values of 0.832 (95% CI: 0.781-0.883), 0.768 (95% CI: 0.711-0.826), and 0.834 (95% CI: 0.783-0.885).</p><p><strong>Conclusions: </strong>Work-family conflict, burnout, occupational stress, the nursing practice environment, and sleep disorders were consistently associated with WPV experiences among emergency department nurses. Random forest achieved the highest sensitivity, F1-score, and overall accuracy, whereas logistic regression showed the highest specificity and balanced accuracy. Logistic regression and random forest demonstrated similar discrimination.</p>","PeriodicalId":11528,"journal":{"name":"Emergency Medicine International","volume":"2026 ","pages":"9275645"},"PeriodicalIF":1.6,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13487808/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148789689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yani Gao, Sheng Bi, Haoran Li, Xiaojin Sun, Chaogang Wei, Xuming Zhao, Yan Xiao
{"title":"Construction of a Mortality Prediction Model for Cardiac Arrest Patients Using Lactate Clearance Rate and Albumin-Corrected Anion Gap.","authors":"Yani Gao, Sheng Bi, Haoran Li, Xiaojin Sun, Chaogang Wei, Xuming Zhao, Yan Xiao","doi":"10.1155/emmi/3964486","DOIUrl":"10.1155/emmi/3964486","url":null,"abstract":"<p><strong>Background: </strong>Cardiac arrest (CA) causes systemic circulatory failure, leading to postcardiac arrest syndrome (PCAS) and high mortality. Lactic clearance rate (LCR) and albumin-corrected anion gap (ACAG) reflect metabolic status but lack combined validation for predicting short-term mortality in CA patients.</p><p><strong>Objective: </strong>This study explores the predictive value of LCR at different time points and ACAG for 7-day mortality in post-CA patients and constructs a predictive model.</p><p><strong>Methods: </strong>Using the MIMIC-IV 3.0 database, we included eligible CA patients and calculated LCR at 6, 12, and 24 h, along with initial ACAG. ROC curves and logistic regression were used to assess predictive value, while restricted cubic splines (RCS) explored mortality risk. The best predictors were selected for model construction, with multivariate logistic regression identifying independent risk factors. Internal and external validations were performed.</p><p><strong>Results: </strong>A total of 821 patients were included, with a 7-day mortality rate of 34.47%. LCR was lower, and ACAG was higher in nonsurvivors (<i>p</i> < 0.05). The 24-h LCR combined with ACAG had the highest predictive efficacy (area under the ROC curve [AUC] = 0.716). Independent risk factors included 24-h LCR, ACAG, CK-MB, shockable rhythm, and CA etiology. The final model achieved an AUC of 0.775 (internal) and 0.743 (external).</p><p><strong>Conclusion: </strong>The 24-h LCR combined with ACAG predicts short-term mortality in post-CA patients who survive the first 24 h, supporting risk stratification after early postresuscitation stabilization.</p>","PeriodicalId":11528,"journal":{"name":"Emergency Medicine International","volume":"2026 ","pages":"3964486"},"PeriodicalIF":1.6,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13478800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148789673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yunus Emre Gemici, Furkan Ay, Alper Görkem Cimen, İbrahim Sarbay, Mustafa Calik
{"title":"Comparison of Bolus and Continuous Hydration Regimens for the Prevention of Contrast-Associated Acute Kidney Injury in the Emergency Department: A Randomized Controlled Noninferiority Trial.","authors":"Yunus Emre Gemici, Furkan Ay, Alper Görkem Cimen, İbrahim Sarbay, Mustafa Calik","doi":"10.1155/emmi/8497484","DOIUrl":"10.1155/emmi/8497484","url":null,"abstract":"<p><strong>Objectives: </strong>The optimal rate and duration of isotonic hydration therapy for preventing contrast-associated acute kidney injury (CA-AKI) remain poorly established. As prolonged hydration therapy is impractical due to the urgency of diagnostic imaging and the limited time available for monitoring in the emergency departments (EDs), this study evaluated whether bolus hydration regimens are noninferior to prolonged hydration protocols.</p><p><strong>Methods: </strong>This single-center, prospective, open-label, randomized controlled, noninferiority trial was conducted at the ED of a training and research hospital between August 10, 2024, and April 26, 2025. 257 patients undergoing contrast-enhanced computed tomography (CT) with baseline creatinine levels above the reference range (1.2 mg/dL in men and 1.1 mg/dL in women) were included. Patients were stratified by age and sex and randomized to bolus or continuous hydration. The bolus group received 500 mL of isotonic fluid within 30 min before the procedure, followed by 500 mL/hour for 2 h postprocedure. The continuous group received 150 mL/hour for 2 h before and 8 h after the procedure. The primary outcome was the development of CA-AKI, defined as an increase in serum creatinine of ≥ 25% or ≥ 0.5 mg/dL at 48-72 h following contrast administration. Secondary outcomes included 30-day all-cause mortality and the need for dialysis.</p><p><strong>Results: </strong>The two groups were well-matched in terms of demographic, clinical, or biochemical parameters. The mean baseline creatinine was 1.4 ± 0.21 mg/dL, and the eGFR was 45.6 ± 9.8 mL/min/1.73 m<sup>2</sup>. CA-AKI occurred in 1.7% of the continuous group and 4.9% of the bolus group (absolute risk difference 3.2%; 95% CI -1.3% to 7.7%). As the upper confidence interval limit was below the predefined noninferiority margin of 8%, bolus hydration was noninferior to continuous hydration for CA-AKI prevention. No patients required dialysis. Thirty-day all-cause mortality was comparable (7.6% vs. 7.9%; <i>p</i> = 0.928). Significant improvements were observed in urea, creatinine, and eGFR values in both groups at 48-72 h (<i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>In this single-center noninferiority trial, a bolus hydration regimen was noninferior to a prolonged continuous regimen for preventing CA-AKI in ED patients with moderately impaired baseline renal function. Bolus hydration may offer a practical alternative in time-constrained ED settings; however, multicenter confirmation is warranted before routine adoption. <b>Trial Registration:</b> ClinicalTrials.gov.identifier: NCT07286526.</p>","PeriodicalId":11528,"journal":{"name":"Emergency Medicine International","volume":"2026 ","pages":"8497484"},"PeriodicalIF":1.6,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13424603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148653161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development and Internal Validation of a Predictive Nomogram for Assessing Rhabdomyolysis Risk After Wasp Stings: A Multicenter Study in Sichuan, China.","authors":"Xiaoyan Xian, Guoqiang Chen, Jianping Hu, Yuanjun Zhang, Mengqin Li, Jing Chen, Jiao Li, Shuyun Xu","doi":"10.1155/emmi/8817533","DOIUrl":"10.1155/emmi/8817533","url":null,"abstract":"<p><p>Wasp venom-induced rhabdomyolysis (RM) is a serious complication associated with poor clinical prognosis. However, predictive models for RM after wasp stings remain limited. This study aimed to develop and internally validate a clinical prediction model for RM in patients with wasp stings. This multicenter retrospective cohort study included 607 patients admitted to five tertiary hospitals in Sichuan Province for wasp stings between February 2015 and December 2020. Least absolute shrinkage and selection operator (LASSO) regression and multivariate logistic regression were used to identify independent predictors of RM. A nomogram incorporating nine predictors was constructed. Model performance was assessed by internal validation and decision curve analysis (DCA). Among the 607 patients, 178 (29.3%) developed RM. Nine predictors were included in the final model: age, sting species, number of stings, tea-colored urine, white blood cell count (WBC), lactate dehydrogenase( LDH), total bilirubin (TBIL), activated partial thromboplastin time (APTT), and month of injury. The nomogram showed excellent discrimination, with an area under the receiver operating characteristic curve (AUC) of 0.949 (95% CI, 0.9319-0.9655) and a concordance index (C-index) of 0.948. DCA suggested good potential clinical utility of the model. We developed a nomogram for early prediction of RM risk after wasp stings using readily available clinical variables. This model may help identify high-risk patients at an early stage and support timely clinical management.</p>","PeriodicalId":11528,"journal":{"name":"Emergency Medicine International","volume":"2026 ","pages":"8817533"},"PeriodicalIF":1.6,"publicationDate":"2026-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13417488/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ashraf F Hefny, Sara E Aldhaheri, Fatima Aldhaheri, Fatima Alameri, Sherif A Fathi, Nirmin A Mansour
{"title":"Relation Between Injury Severity and Fractures of the First and/or Second Ribs in Blunt Chest Trauma at a Community-Based Hospital: A Retrospective Study.","authors":"Ashraf F Hefny, Sara E Aldhaheri, Fatima Aldhaheri, Fatima Alameri, Sherif A Fathi, Nirmin A Mansour","doi":"10.1155/emmi/4297853","DOIUrl":"10.1155/emmi/4297853","url":null,"abstract":"<p><strong>Objective: </strong>Trauma is a major global health concern that contributes significantly to morbidity and mortality worldwide. Road traffic collisions (RTCs) are the most common cause of blunt chest trauma (BCT). First and/or second rib fractures (FSRFs) are often indicative of high-energy trauma. This study investigated the incidence, mechanisms of injury, management, and outcomes of FSRF in patients with BCT at a community-based hospital.</p><p><strong>Methods: </strong>Data were retrospectively collected from all patients with BCT admitted to Al Ain Hospital between December 2014 and January 2020. Data for patients with FSRF were specifically reviewed. Information was obtained from the Al Ain Hospital Trauma Registry, which included all patients of all age groups who were admitted to the hospital or died in the emergency department during the study period.</p><p><strong>Results: </strong>During the study period, 958 patients with BCT were admitted to our institution, of whom 86 (9%) had FSRF. The most common mechanism of trauma was RTC in 62 (72.1%) patients. Patients with FSRF had significantly higher injury severity scores than those of patients with BCT without FSRF. Three patients with FSRF died (overall mortality, 3.5%) compared with 17 (1.9%) patients without FSRF. This difference was not statistically significant (<i>p</i> = 0.341, chi-squared test).</p><p><strong>Conclusions: </strong>This study is consistent with previous reports demonstrating that FSRFs are associated with high-energy trauma and potentially serious intrathoracic and extrathoracic injuries. The importance of these fractures in blunt trauma should be recognized to endorse close monitoring and timely therapeutic intervention, which is supported by existing literature.</p>","PeriodicalId":11528,"journal":{"name":"Emergency Medicine International","volume":"2026 ","pages":"4297853"},"PeriodicalIF":1.6,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13408435/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xuyong Chen, Shasha Ying, Xiangshu Yuan, Lihong Lv, Xingyi Yang
{"title":"Prognostic Value of the Total Bilirubin-to-Albumin Ratio in Critically Ill Patients with Gastrointestinal Bleeding: A Multicentre Cohort Study.","authors":"Xuyong Chen, Shasha Ying, Xiangshu Yuan, Lihong Lv, Xingyi Yang","doi":"10.1155/emmi/1396680","DOIUrl":"10.1155/emmi/1396680","url":null,"abstract":"<p><strong>Introduction: </strong>The total bilirubin-to-serum albumin ratio (TBAR) has been proposed as an indicator of hepatic dysfunction and systemic inflammation, yet its prognostic relevance in critically ill patients with gastrointestinal bleeding (GIB) remains unclear. This study evaluated the association between TBAR and mortality and developed a TBAR-based prognostic model.</p><p><strong>Methods: </strong>Data were extracted from the MIMIC-IV v3.1 database, with external validation using the eICU-CRD v2.0. Adult patients with GIB were included after applying predefined eligibility criteria, yielding a final cohort of 1627 individuals. The primary outcomes were 28-day all-cause mortality. Cox regression, Kaplan-Meier analyses, restricted cubic splines (RCS), ROC curves, and subgroup analyses were performed. A prediction nomogram was constructed using variables selected through the Boruta algorithm and evaluated using AUC, C-index, calibration performance, and decision curve analysis.</p><p><strong>Results: </strong>Nonsurvivors exhibited markedly greater physiological instability, more severe organ dysfunction, and substantially higher TBAR levels. TBAR was independently associated with mortality across all Cox models (fully adjusted HR for 28-day mortality: 1.10, 95% CI 1.06-1.15). High TBAR was associated with more than a twofold increased risk of death. TBAR demonstrated superior discriminatory ability compared with TBIL or ALB alone and provided incremental predictive value when combined with the SOFA score. RCS analysis supported a linear dose-response association. Subgroup analyses showed no significant interactions. The final nomogram-which incorporated SOFA, APTT, TBAR, vasopressor use, CRRT, and anion gap-achieved an AUC of 0.794 and a bootstrap-corrected C-index of 0.789. External validation in the eICU cohort confirmed the robustness of the association and the strong performance of the model (AUC 0.805).</p><p><strong>Conclusions: </strong>TBAR is an independent predictor of mortality in critically ill patients with GIB. The TBAR-based nomogram demonstrates reliable discrimination and calibration and may facilitate individualized mortality risk stratification in clinical practice.</p>","PeriodicalId":11528,"journal":{"name":"Emergency Medicine International","volume":"2026 ","pages":"1396680"},"PeriodicalIF":1.6,"publicationDate":"2026-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13401164/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148591102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Efficacy of Standardized Care for Abdominal Drainage Tubes in the Treatment of Acute Appendicitis: A Single-Center Retrospective Cohort Study.","authors":"Jiamei Lin, Yanan Zhou, Zipeng Xu, Wenhui Shi, Yan Huang, Genxi Tong, Fengjun Cai, Qinyan Yang, Chaobo Chen","doi":"10.1155/emmi/7131025","DOIUrl":"10.1155/emmi/7131025","url":null,"abstract":"<p><strong>Objective: </strong>Although abdominal drainage (AD) tubes have become an effective means to prevent and observe complications after laparoscopic appendectomy (LA), there are still controversies, and no standardized nursing process (SNP) is shown for the management of drainage tube care. This investigation aims to assess the effectiveness of SNP management in AD tubes after LA.</p><p><strong>Methods: </strong>This retrospective cohort investigation comprised individuals who had LA surgery with abdominal drain placement for acute appendicitis from July 2021 to June 2024. Individuals were classified into the SNP and non-SNP groups. A comparison of the outcomes was conducted, while univariate and multivariate analyses were conducted to assess the factors related to the SNP. <i>p</i>-value < 0.05 was regarded as significant.</p><p><strong>Results: </strong>A total of 367 patients were enrolled in this investigation, and no significant variations were shown in baseline characteristics between the SNP (<i>n</i> = 199) and non-SNP groups (<i>n</i> = 168). Multivariable logistic regression analysis displayed that SNP management was an important factor in decreasing postoperative 24-h pain scores (OR = 0.22, 95% CI: 0.12-0.42, <i>p</i> < 0.001), improving the out-of-bed activity rate (OR = 2.33, 95% CI: 1.37-3.96, <i>p</i> < 0.05) and patient's degree of satisfaction after surgery (OR = 16.02, 95% CI: 9.06-28.32, <i>p</i> < 0.001). However, SNP had no significant effect on the incidence of postoperative drainage tube dislodgement (OR = 0.49, 95% CI: 0.16-1.51, <i>p</i> > 0.05).</p><p><strong>Conclusions: </strong>In this retrospective cohort, the implementation of SNP was associated with significantly lower postoperative 24-h pain scores, a higher out-of-bed activity rate, and greater patient satisfaction after LA surgery. These findings suggest that SNP may be a beneficial component of postoperative care and warrant further investigation.</p>","PeriodicalId":11528,"journal":{"name":"Emergency Medicine International","volume":"2026 ","pages":"7131025"},"PeriodicalIF":1.6,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13390735/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148560961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}