E-journal of Chemistry最新文献_第6页

Validated Spectrophotometric Assay of Cefepime Hydrochloride and Cefuroxime Sodium Using a Tetrazolium Salt 盐酸头孢吡肟和头孢呋辛钠的四唑盐分光光度法测定

E-journal of Chemistry Pub Date : 2012-01-01 DOI: 10.1155/2012/959624

M. El-Azazy, A. Shalaby

{"title":"Validated Spectrophotometric Assay of Cefepime Hydrochloride and Cefuroxime Sodium Using a Tetrazolium Salt","authors":"M. El-Azazy, A. Shalaby","doi":"10.1155/2012/959624","DOIUrl":"https://doi.org/10.1155/2012/959624","url":null,"abstract":"A simple, rapid and sensitive spectrophotometric method for the determination of micro amounts of cefepime hydrochloride and cefuroxime sodium is described. The method is based on reduction of 2,3,5-triphenyltetrazolium chloride (TTC) by the cited drugs in slightly alkaline medium leading to formation of a highly colored formazan derivative. Different variables affecting the color development were investigated and optimized. Absorbance measurements were made at 483 nm. Under the proposed conditions, this method is applicable over concentration range of 4–50 µg ml-1 with molar absorpitivities ranging from 5.208 x 103–1.217 x 104 L.mol-1.cm-1 and Sandell's sensitivities ranging from 1.007 x 10-3–2.727 x10-3 µg cm-2. The proposed method was successfully applied for analysis of the cited drugs in formulations and the recovery percentages ranged from 99.47 to 99.8%. The results obtained demonstrated that the proposed method is equally accurate, precise and reproducible as the reported methods thus it is recommended for quality control and routine analysis where time, cost effectiveness and high specificity of analytical techniques are of great importance.","PeriodicalId":11519,"journal":{"name":"E-journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2012/959624","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64371129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Efficient Production Process for Food Grade Acetic Acid by Acetobacter aceti in Shake Flask and in Bioreactor Cultures 醋酸杆菌摇瓶和生物反应器高效生产食品级醋酸的工艺研究

E-journal of Chemistry Pub Date : 2012-01-01 DOI: 10.1155/2012/965432

H. Awad, Richard Díaz, R. Malek, N. Othman, R. Aziz, H. E. Enshasy

{"title":"Efficient Production Process for Food Grade Acetic Acid by Acetobacter aceti in Shake Flask and in Bioreactor Cultures","authors":"H. Awad, Richard Díaz, R. Malek, N. Othman, R. Aziz, H. E. Enshasy","doi":"10.1155/2012/965432","DOIUrl":"https://doi.org/10.1155/2012/965432","url":null,"abstract":"Acetic acid is one of the important weak acids which had long history in chemical industries. This weak organic acid has been widely used as one of the key intermediate for many chemical, detergent, wood and food industries. The production of this acid is mainly carried out using submerged fermentation system and the standard strain Acetobacter aceti. In the present work, six different media were chosen from the literatures and tested for acetic acid production. The highest acetic acid production was produced in medium composed of glucose, yeast extract and peptone. The composition of this medium was optimized by changing the concentration of medium components. The optimized medium was composed of (g/L): glucose, 100; yeast extract, 12 and peptone 5 and yielded 53 g/L acetic acid in shake flask after 144 h fermentation. Further optimization in the production process was achieved by transferring the process to semi-industrial scale 16-L stirred tank bioreactor and cultivation under controlled pH condition. Under fully aerobic conditions, the production of acetic acid reached maximal concentration of about 76 g/L and 51 g/L for uncontrolled and controlled pH cultures, respectively.","PeriodicalId":11519,"journal":{"name":"E-journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2012/965432","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64371312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 19

Indirect Electrochemical Analysis of Crocin in Phytochemical Sample 植物化学样品中藏红花素的间接电化学分析

E-journal of Chemistry Pub Date : 2012-01-01 DOI: 10.1155/2012/967079

R. A. Dar, Pradeep Kumar Brahaman, S. Tiwari, K. S. Pitre

{"title":"Indirect Electrochemical Analysis of Crocin in Phytochemical Sample","authors":"R. A. Dar, Pradeep Kumar Brahaman, S. Tiwari, K. S. Pitre","doi":"10.1155/2012/967079","DOIUrl":"https://doi.org/10.1155/2012/967079","url":null,"abstract":"A new electroanalytical method has been developed for the quantitative determination of crocin in a sample of stigmas of saffron (Crocus sativus L.). Crocin is polarographically inactive. However, cysteine in 0.02 M NaCl, pH=5.2±0.01 produces a well defined wave/peak with E1/2/Ep= –0.47/–0.45 V vs. Ag/AgCl. On recording polarograms of a set of solution containing a fixed concentration of cysteine and varying concentrations of crocin under aforesaid experimental conditions a gradual decrease in peak height/diffusion current and a negative shift in peak potential was observed. Thus, indicating cysteine-crocin interaction. Amperometric titration indicated crocin to cysteine ratio of 1:2. The above amperometric titration procedure has been used to determine the concentration of crocin in a sample of saffron. Crystallization process was carried out for the extraction of crocin from dried powder of saffron stigmas. The crystallized crocin was identified by UV-Visible spectrophotometry(at 255 nm and 442 nm) and the quantitative analysis by the developed amperometric method. The concentration of crocin in saffron was found to be 2.13% and purity of isolated crocin 96.81%. The percent recovery varied from 98.56–100.31% and RSD (n=5) of 2.17%.The validation of the proposed procedure for the quantitative assay of crocin was examined via an evaluation of the repeatability, recovery, selectivity and relative standard deviation.","PeriodicalId":11519,"journal":{"name":"E-journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2012/967079","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64371395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Staminate Flower of Cocos Nucifera as Green Inhibitor for Mild Steel in HCl Medium 在HCl介质中对低碳钢的抑绿作用

E-journal of Chemistry Pub Date : 2012-01-01 DOI: 10.1155/2012/138463

R. Rajalakshmi, A. Safina

{"title":"Staminate Flower of Cocos Nucifera as Green Inhibitor for Mild Steel in HCl Medium","authors":"R. Rajalakshmi, A. Safina","doi":"10.1155/2012/138463","DOIUrl":"https://doi.org/10.1155/2012/138463","url":null,"abstract":"Corrosion control methods, especially the use of inhibitors, have gained monumental importance in the present scenario of expunging corrosion and the quest for eco-friendly reasons continues. To arrive at an inexpensive non-toxic, eco-friendly inhibitor formulations the present study on the use of Staminate Flower extract of Cocos Nucifera has been carried out by the classical weight loss measurements and electrochemical polarization measurements. The acid extract could bring out a maximum of 97.3% inhibition of mild steel corrosion in 1M HCl. Thermodynamic parameters of the corrosion process were calculated from temperature study. The adsorptive behaviour of Staminate Flower extract in acid solution may be approximated both by Langmuir and Temkin type isotherms. The results obtained by Tafel, Linear polarization resistance, and impedance spectroscopy have been correlated with the classical weight loss measurements. Values of Tafel constant ba and bc confirmed that the Staminate Flower extract acts like mixed type inhibitor. Examination of the surface of the metal in the presence of the inhibitor confirmed the deposition of inhibitor on the metal surface. The Staminate Flower extract in HCl medium efficiently inhibits the corrosion and proved to be zero cost inhibitor, eco-friendly, non-toxic, and highly economical.","PeriodicalId":11519,"journal":{"name":"E-journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2012/138463","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64295321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Melamine Trisulfonic Acid as a Highly Efficient and Reusable Catalyst for the Synthesis of β-Acetamido Ketones 三聚氰胺三磺酸作为合成β-乙酰胺酮的高效可重复使用催化剂

E-journal of Chemistry Pub Date : 2012-01-01 DOI: 10.1155/2012/173197

A. Zare

引用次数: 3

Development, Estimation and Validation of Lisinopril in Bulk and its Pharmaceutical Formulation by HPLC Method 赖诺普利原料药及其制剂的高效液相色谱法开发、评价与验证

E-journal of Chemistry Pub Date : 2012-01-01 DOI: 10.1155/2012/292754

V. B. Raju, A. Rao

引用次数: 7

New Spectrophotometric Method for the Determination of Bosentan - An Anti-Hypertensive Agent in Pharmaceutical Dosage Forms 分光光度法测定药物剂型中降压药波生坦含量的新方法

E-journal of Chemistry Pub Date : 2012-01-01 DOI: 10.1155/2012/359745

A. Narendra, D. Deepika, M. M. Annapurna