EndoscopyPub Date : 2026-11-01Epub Date: 2026-10-23DOI: 10.1055/a-2938-6119
Julia L Gauci, Michael J Bourke
{"title":"Reply to Masunaga and Kato.","authors":"Julia L Gauci, Michael J Bourke","doi":"10.1055/a-2938-6119","DOIUrl":"https://doi.org/10.1055/a-2938-6119","url":null,"abstract":"","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":"58 11","pages":"1356-1357"},"PeriodicalIF":11.8,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149243284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EndoscopyPub Date : 2026-11-01Epub Date: 2026-10-23DOI: 10.1055/a-2945-2063
Shisong Wang, Jiarong Xie, Lei Xu
{"title":"Reply to Wang et al.","authors":"Shisong Wang, Jiarong Xie, Lei Xu","doi":"10.1055/a-2945-2063","DOIUrl":"https://doi.org/10.1055/a-2945-2063","url":null,"abstract":"","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":"58 11","pages":"1353"},"PeriodicalIF":11.8,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149243579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EndoscopyPub Date : 2026-10-22DOI: 10.1055/a-2955-8772
Qingwei Jiang, Xiyi An, Xiaxiao Yan, Ziqi Guo, Yuelun Zhang, Na Li, Junjie Ren, Pan Li, Ying Tu, Hui Ding, Ailing Liu, Dekun Yang, Zhizhi Wang, Jie Liu, Ruigang Wang, Shanhong Tang, Lin Jin, Ai-Ming Yang, Dong Wu
{"title":"Cold versus hot snare endoscopic mucosal resection for 10-19-mm nonpedunculated colorectal polyps: a multicenter randomized trial.","authors":"Qingwei Jiang, Xiyi An, Xiaxiao Yan, Ziqi Guo, Yuelun Zhang, Na Li, Junjie Ren, Pan Li, Ying Tu, Hui Ding, Ailing Liu, Dekun Yang, Zhizhi Wang, Jie Liu, Ruigang Wang, Shanhong Tang, Lin Jin, Ai-Ming Yang, Dong Wu","doi":"10.1055/a-2955-8772","DOIUrl":"https://doi.org/10.1055/a-2955-8772","url":null,"abstract":"<p><strong>Background: </strong>Evidence for cold snare endoscopic mucosal resection (CS-EMR) in 10-19-mm nonpedunculated colorectal polyps is scarce. We conducted a multicenter randomized controlled trial (RCT) to compare CS-EMR against hot snare EMR (HS-EMR) in this setting.</p><p><strong>Methods: </strong>We enrolled patients with 10-19-mm nonpedunculated colorectal polyps from 15 centers. Eligible polyps were individually randomized (1:1) to CS-EMR or HS-EMR. The primary outcome was histologic complete resection, analyzed in modified intention-to-treat (mITT) and per-protocol (PP) populations (noninferiority margin -10%). Secondary outcomes included en bloc resection, intraprocedural and delayed adverse events, and resection time.</p><p><strong>Results: </strong>216 patients with 233 eligible polyps were included (CS-EMR 116; HS-EMR 117). In the mITT analysis, complete resection was 90.4% in the CS-EMR group and 93.2% in the HS-EMR group (difference -2.7%, 95%CI -9.8 to 4.3), showing noninferiority of CS-EMR vs. HS-EMR. PP results were consistent (CS-EMR 93.3%; HS-EMR 93.2%; difference 0.2%, 95%CI -6.7 to 7.1). CS-EMR was noninferior for 10-14-mm polyps (94.3% vs. 94.0%; 95%CI -6.8 to 7.2) but not for 15-19-mm polyps (78.6% vs. 90.9%; 95%CI -30.4 to 5.8), although interaction was not significant. En bloc resection rates and resection time were similar between groups. Intraprocedural bleeding was more frequent with CS-EMR (19.1% vs. 3.4%), whereas delayed bleeding was rare (0.0% vs. 0.9%), and no perforation occurred in either group.</p><p><strong>Conclusion: </strong>CS-EMR was noninferior to HS-EMR for histologic complete resection of 10-19-mm nonpedunculated colorectal polyps, but its applicability to 15-19-mm lesions remains uncertain.</p>","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":" ","pages":""},"PeriodicalIF":11.8,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149243710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EndoscopyPub Date : 2026-10-22DOI: 10.1055/a-2964-7886
Carlo Fabbri, Cecilia Binda, Julio Iglesias Garcia, Ilaria Tarantino, Alberto Larghi, Wim Laleman, Paolo Giorgio Arcidiacono, Virginia Hernandez-Gea, Annalisa Berzigotti, Andrada Seicean, Stefano Francesco Crinò, Andrea Anderloni, John Gásdal Karstensen, Giuseppe Vanella, Jayanta Samanta, Francesco Santopaolo, Antonio Facciorusso, Schalk W Van der Merwe, Lorenzo Fuccio
{"title":"Endoscopic ultrasound in hepatology: A European Society of Gastrointestinal Endoscopy (ESGE) Technical and Technology Review.","authors":"Carlo Fabbri, Cecilia Binda, Julio Iglesias Garcia, Ilaria Tarantino, Alberto Larghi, Wim Laleman, Paolo Giorgio Arcidiacono, Virginia Hernandez-Gea, Annalisa Berzigotti, Andrada Seicean, Stefano Francesco Crinò, Andrea Anderloni, John Gásdal Karstensen, Giuseppe Vanella, Jayanta Samanta, Francesco Santopaolo, Antonio Facciorusso, Schalk W Van der Merwe, Lorenzo Fuccio","doi":"10.1055/a-2964-7886","DOIUrl":"https://doi.org/10.1055/a-2964-7886","url":null,"abstract":"<p><strong>Background: </strong>Endoscopic ultrasound (EUS)-guided techniques are increasingly applied in hepatology, including for tissue acquisition, vascular access, pressure measurement, and selected therapeutic interventions. However, adoption remains heterogeneous because of variability in technical approaches, devices, outcome definitions, operator expertise, and the quality of available evidence.</p><p><strong>Methods: </strong>This European Society of Gastrointestinal Endoscopy (ESGE) Technical and Technology Review summarizes the current evidence on selected EUS-guided techniques in liver disease and portal hypertension, including liver stiffness assessment, focal liver lesion characterization and sampling, EUS-guided liver biopsy, EUS-guided portal pressure gradient measurement, therapy for gastric varices, and portal vein sampling for liquid biopsy applications. Evidence was identified through a structured literature search up to April 2026, and recommendation statements were graded using the GRADE framework.</p><p><strong>Results: </strong>Eight ESGE statements were developed. The available evidence supports selected use of EUS-guided shear wave elastography and contrast-enhanced EUS as adjunctive techniques; EUS-guided liver biopsy and EUS-guided portal pressure gradient measurement as complementary approaches in selected patients and expert centers; and EUS-guided treatment of gastric varices as a valid alternative to direct endoscopic injection where appropriate expertise is available. Portal vein sampling remains investigational. Across the indications, the evidence base is limited by small studies, heterogeneous techniques, variable outcome definitions, and limited prospective comparative data.</p><p><strong>Conclusions: </strong>This review provides an evidence-based framework for the selective use of EUS-guided techniques in hepatology and portal hypertension. Wider adoption will require standardized techniques, structured training, consistent outcome definitions, and prospective comparative studies.</p>","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":" ","pages":""},"PeriodicalIF":11.8,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149243830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EndoscopyPub Date : 2026-10-22DOI: 10.1055/a-2974-6039
Ivo Mendes, Carolina Palma, Carolina Renda Rodrigues, Susana Alexandra Henriques, Ana Maria Monteiro, Gonçalo Nunes
{"title":"Endoscopic treatment of colorectal anastomotic leakage with an innovative hybrid vacuum stent.","authors":"Ivo Mendes, Carolina Palma, Carolina Renda Rodrigues, Susana Alexandra Henriques, Ana Maria Monteiro, Gonçalo Nunes","doi":"10.1055/a-2974-6039","DOIUrl":"https://doi.org/10.1055/a-2974-6039","url":null,"abstract":"","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":" ","pages":""},"PeriodicalIF":11.8,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149243810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}