Dysphagia最新文献

{"title":"Upper Esophageal Sphincter Abnormalities and Esophageal Motility Recovery After Peroral Endoscopic Myotomy for Achalasia.","authors":"Sihui Lin, Tiancheng Luo, Zhilong Chen, Yucheng Zhu, Shuqiang Weng, Wei Jiang, Hong Gao","doi":"10.1007/s00455-024-10773-4","DOIUrl":"10.1007/s00455-024-10773-4","url":null,"abstract":"<p><p>Abnormalities in the upper esophageal sphincter (UES) in patients with achalasia and the impact of peroral endoscopic myotomy (POEM) on the UES and esophageal body remain uncertain. To outline the prevalence and nature of UES abnormalities across different achalasia subtypes, as well as evaluate POEM's therapeutic efficacy on UES and esophageal body. A retrospective study of patients diagnosed with achalasia between January 2019 and December 2023 was conducted. POEM was performed on all patients, and preoperative and 6-month postoperative high-resolution esophageal manometry (HREM) data were obtained, along with the Eckardt symptom scores. A total of 64 patients (34 females, 30 males) who underwent POEM for achalasia (type I: 18, type II: 38, type III: 8) during the study period were included. Among the 64 patients, 42 (65.6%) exhibited abnormalities in the UES, as observed on HREM. The majority of those exhibiting abnormalities demonstrated impaired relaxation of the UES (46.9%), followed by a combination of hypertensive basal UES pressure (UESP) and impaired UES relaxation (12.5%). The dysphagia score and Eckardt score before POEM were significantly greater in the UES abnormality group than in the normal UES group (2.3 ± 0.7 vs. 1.9 ± 0.7, p = 0.040 and 6.2 ± 1.8 vs. 5.0 ± 1.6, p = 0.008, respectively). UESP and UES relaxation pressure (UESRP) decreased significantly following POEM across all types of achalasia (p < 0.05). All type I patients continued to exhibit no contractility after undergoing POEM. Pan-esophageal pressurization and spastic contractions were absent in patients with type II and type III achalasia following POEM. The high prevalence of UES abnormalities among patients with achalasia may serve as a compensatory mechanism. Patients with type II and III showed partial recovery of peristalsis following POEM.</p>","PeriodicalId":11508,"journal":{"name":"Dysphagia","volume":" ","pages":"759-766"},"PeriodicalIF":3.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12328482/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142727071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Swallow Examination Following Laryngectomy: An International e-Delphi Consensus Process.","authors":"Sarah E Wilson, Bena Brown, Clare L Burns","doi":"10.1007/s00455-024-10785-0","DOIUrl":"10.1007/s00455-024-10785-0","url":null,"abstract":"<p><p>Clinical swallow examination (CSE) following laryngectomy (± pharyngeal resection) remains a critical step in dysphagia evaluation. Whilst the core components of a standard CSE service a broad spectrum of patient populations, no evidence exists examining the essential assessment items specific to CSE in the laryngectomy population. The aim of this study was to identify the tasks, measures and observations considered necessary to include in a CSE post laryngectomy. Using an e-Delphi approach, a 4-round online survey series was undertaken with 34 speech pathologists experienced in laryngectomy swallowing management from 6 countries. In the first round (item generation) participants were provided with the questions from the swallowing outcomes after laryngectomy (SOAL) as stimulus, to generate a list of tasks, measures and observations as well as clarifying questions they would ask the patient during a CSE. In the subsequent e-Delphi rounds the participants rated the importance of the compiled assessment items. A total of 34 items were rated of critical importance for inclusion in a laryngectomy CSE by ≥ 75% of participants. Two thirds of the consensus items (23 items) were patient history and interview questions incorporating medical and swallowing history (4 items) and patient interview (19 items). The remaining 11 items related to swallow tasks and observations (9 items) and onward referral (2 items). These 34 consensus items can be considered as a draft framework for laryngectomy CSE to guide clinical practice and research.</p>","PeriodicalId":11508,"journal":{"name":"Dysphagia","volume":" ","pages":"869-885"},"PeriodicalIF":3.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12328528/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"'Without the Data You're Not Going to Know If It's Important or Not': A Mixed Methods Study on What Dysphagia Intervention Outcomes are Important to People with Parkinson's Disease and Family Members.","authors":"J Hirschwald, L Mooney, M Wolf, G Boyle, T Warnecke, M Walshe","doi":"10.1007/s00455-024-10788-x","DOIUrl":"10.1007/s00455-024-10788-x","url":null,"abstract":"<p><p>The lack of patient and public involvement in oropharyngeal dysphagia (OD) intervention studies in Parkinson's disease (PD) can bias the choice of outcomes to be measured in these studies. This study aimed to obtain perspectives of individuals living with OD in PD and family members/caregivers on OD intervention outcomes that are important to them. This is part of a larger Core Outcome Set project. A mixed methods study with an international online cross-sectional survey and subsequent focus groups involving people with OD in PD and family members/caregivers was conducted. Survey results were analyzed using descriptive and inferential statistics. Intervention outcomes rated most important, significantly different, inconclusive, or identified as missing in the survey were clarified in follow-up focus groups with seven previous survey participants. Focus group data were audio recorded, transcribed verbatim and analyzed following inductive and deductive content analysis using NVivo. Twelve outcomes were rated as important by ≥ 80% of the 62 survey participants. The most important outcomes were penetration/aspiration and laryngeal sensation. Fear of choking was added as an important but missing intervention outcome. In the focus groups, findings from the survey were validated. Four content categories with eleven sub-categories were identified. OD intervention outcome priorities by people with OD in PD and family members/caregivers show only partial agreement with outcomes measured in published intervention studies on OD in PD. This highlights the importance of stakeholder involvement in the design and implementation of these studies to make findings relevant to all.</p>","PeriodicalId":11508,"journal":{"name":"Dysphagia","volume":" ","pages":"902-919"},"PeriodicalIF":3.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measurement Properties of the Dysphagiameter for the Assessment of Dysphagia in Oculopharyngeal Muscular Dystrophy.","authors":"Claudia Côté, Bernard Brais, Charles Sèbiyo Batcho, Jean-Denis Brisson, Sarah Youssof, Emmanuel Sègnon Sogbossi, Cynthia Gagnon","doi":"10.1007/s00455-024-10791-2","DOIUrl":"10.1007/s00455-024-10791-2","url":null,"abstract":"<p><p>Oculopharyngeal muscular dystrophy (OPMD) is a rare late-onset muscle disease with progressive dysphagia as a major symptom. The Dysphagiameter is a newly developed patient-reported outcome measure (PROM) to assess the severity of dysphagia and its impact in patients with OPMD. This article reports on item reduction and a first assessment of the Dysphagiameter's psychometrics properties, in a French and English-speaking population of individuals with OPMD. Classical test theory and Rasch model were used for item reduction and scoring (n = 162). Construct validity was assessed using the time to drink 80 ml of cold water and the Sydney Swallow Questionnaire (SSQ) (n = 40). Part A of the final PROM resulted in a 21-item scale assessing the capacity to swallow foods of various textures and a 3-item scale assessing the capacity to swallow liquids (Cronbach Alpha = 0.90); the hierarchical structure of the 21-item scale was confirmed with a Rasch analysis (Person separation index = 0.95). Part B resulted in a 6 item-scale assessing the impact on mealtime and a 2-item scale assessing discomfort related to thick saliva (Alpha Cronbach = 0.91 and 0.79). Convergent validity was demonstrated by significant correlations with the SSQ. Known-group validity was supported by the ability of the Dysphagiameter to detect significant differences according to the severity of dysphagia. In summary, the Dysphagiameter-OPMD, a newly developed PROM, exhibits strong psychometric properties and holds promise as a valuable tool for assessing the severity of dysphagia and its impact on individuals with OPMD.</p>","PeriodicalId":11508,"journal":{"name":"Dysphagia","volume":" ","pages":"931-942"},"PeriodicalIF":3.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Compensatory Swallowing Strategies Recommended in Oncology Practice: Practice Patterns and Relationship to Dynamic Imaging Grade of Swallowing Toxicity (DIGEST) Grades.","authors":"Barbara M Ebersole, Julianna Chapman, Carla L Warneke, Sheila Buoy, X Tang, Holly McMillan, Ella Aldridge, Carly E A Barbon, Katherine A Hutcheson","doi":"10.1007/s00455-024-10799-8","DOIUrl":"10.1007/s00455-024-10799-8","url":null,"abstract":"<p><p>Compensatory swallow strategies are recommended to improve swallow safety and efficiency; however, there is limited evidence on use in specific populations or their relationship to swallow study results. We sought to describe/explore strategy recommendations in an oncology practice and their relationship to Dynamic Imaging Grade of Swallowing Toxicity (DIGEST) grades as a marker of clinical utility of the tool. This is a sub-study of a STARI-guided retrospective implementation evaluation at a single comprehensive cancer center. Electronic health record databases were queried to sample all modified barium swallow studies (MBS) for all adult oncology patients from 2016 to 2021, excluding total laryngectomy, leak studies and those with missing DIGEST grades. For patients with multiple MBS studies across the study period, one MBS was randomly selected to be included in the analytic sample. DIGEST grade, diet recommendation, oncologic details, and swallow strategy details were chart abstracted. Strategies and oral intake recommendations were classified from least to most restrictive. This study included 4570 patients representing diverse oncology populations (46% head and neck). DIGEST grades indicating at least mild dysphagia (grades ≥ 1) were reported in 2486 of MBS (54%). Strategies were recommended in 2028 MBS (44%). As DIGEST grade increased so did strategy utilization and complexity (Spearman's r (r_S) = 0.76, p < 0.0001). This pattern was consistent for Safety (r_S = 0.68) and Efficiency (r_S = 0.73) grades (both p < 0.0001). Swallow strategies are frequently recommended in oncology populations. This is the first study to show a systematic link between DIGEST grade and MBS compensatory strategy recommendations, supporting clinical effectiveness of DIGEST as an evidence-based practice tool.</p>","PeriodicalId":11508,"journal":{"name":"Dysphagia","volume":" ","pages":"998-1007"},"PeriodicalIF":3.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kinematic Measurements of Swallowing by Ultrasound: A Scoping Review.","authors":"S L P Giovanna da Silva Martins, Manuela Leitão de Vasconcelos, Jayne de Freitas Bandeira, Desiré Dominique Diniz de Magalhães, Giorvan Anderson Dos Santos Alves, Leandro Pernambuco","doi":"10.1007/s00455-024-10768-1","DOIUrl":"10.1007/s00455-024-10768-1","url":null,"abstract":"<p><p>Ultrasound (US) is a non-invasive method used to study the kinematics of the swallowing function. Kinematic measurements are reported in studies evaluating swallowing using US, but there is no standardization. The aim of this scoping review was to identify and characterize the kinematic measurements of swallowing obtained by ultrasound. We followed the methodological recommendations of the Joanna Briggs Institute (JBI) and the reporting guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analysis-extension for scoping reviews (PRISMA-ScR). The research question followed the acronym PCC (population, concept, and context). Seven databases and gray literature were searched. Studies were selected using a blind, paired, and independent method. Data were extracted using a standardized tool. There were 2591 studies and 42 were eligible. Most studies had samples of less than 30 participants and mostly included healthy young adults and older people. The swallowing tasks during the assessments were not standardized. The most commonly studied measures were hyoid displacement and tongue movement during swallowing. However, there is no consensus between studies on the definition of the measures and the procedures for ultrasound assessment, including image acquisition and analysis.</p>","PeriodicalId":11508,"journal":{"name":"Dysphagia","volume":" ","pages":"681-699"},"PeriodicalIF":3.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142497104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Upper Airway Sensory Testing in Dysphagia - Implications for Clinical Practice and Future Research Directions.","authors":"Norita Regio, Ruby Hutton, Emma S Wallace","doi":"10.1007/s00455-024-10789-w","DOIUrl":"10.1007/s00455-024-10789-w","url":null,"abstract":"<p><p>Adequate upper airway (oral, pharyngeal and laryngeal) sensation is crucial for safe and efficient swallowing and airway protection. Despite its importance, methods of upper airway sensory testing for individuals with dysphagia remain poorly defined. The aim of this study was to summarise and appraise current methods of upper airway sensory testing to inform dysphagia clinical practice and future research directions. A systematic review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Studies that reported a method of upper airway sensory testing in individuals with dysphagia were included. Of the 1187 studies identified and screened, 54 met the inclusion criteria. Four types of upper airway sensory testing were reported: Flexible Endoscopic Evaluation of Swallowing with Sensory Testing (n = 31), Cough Reflex Testing (n = 22), Gag Reflex Testing (n = 5) and Gustatory (taste) Testing (n = 2). Indeterminate \"tests of sensory function\" (n = 2) were also reported. Variability in methods was evident across studies and reporting was insufficient for reliable replication. This review provides a comprehensive overview of methods of upper airway sensory testing in the dysphagia literature for dysphagia clinicians and researchers. The results indicate a need to develop a valid and reliable upper airway sensory testing protocol for individuals with dysphagia to improve assessment and targeted treatments.</p>","PeriodicalId":11508,"journal":{"name":"Dysphagia","volume":" ","pages":"920-930"},"PeriodicalIF":3.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12328471/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between Quality of Life and Swallowing in Hypertensive Individuals with Obstructive Sleep Apnea.","authors":"Carla Rocha Muniz, Thalyta Georgia Vieira Borges, Flavia Rodrigues Ferreira, Mariana Pinheiro Brendim, Elizabeth Silaid Muxfeldt","doi":"10.1007/s00455-024-10783-2","DOIUrl":"10.1007/s00455-024-10783-2","url":null,"abstract":"<p><strong>Introduction: </strong>Obstructive sleep apnea (OSA) is closely associated with resistant hypertension (RHTN). Individuals with OSA may have sensory and muscular alterations in pharyngolaryngeal structures, potentially resulting in oropharyngeal dysphagia.</p><p><strong>Objective: </strong>One objective of this study was to assess and compare the quality of life (QoL) and swallowing ability of resistant hypertensive patients with and without OSA. Another objective was to evaluate the relationship between QoL and changes in swallowing in patients with RHTN and OSA.</p><p><strong>Methods: </strong>This work was an analytical observational study with a cross-sectional design that included resistant hypertensive patients who were undergoing polysomnography (the gold standard exam for the diagnosis of OSA), fiberoptic endoscopic evaluation of swallowing (FEES), dysphagia risk assessment (Eating Assessment Tool - EAT-10) and QoL assessment in swallowing (Swal-Qol).</p><p><strong>Results: </strong>Of the 65 participants, 13 (20%) did not have OSA, 13 (20%) had mild OSA, 18 (27.7%) had moderate OSA, and 21 (32.2%) had severe OSA. Compared with those without OSA, patients with OSA had lower swallowing QoL scores (\"burden\", \"symptoms\", and \"mental health\"). Furthermore, pre premature leakage, onset of the pharyngeal phase in the pyriform sinus, laryngeal penetration, pharyngeal residue and oropharyngeal dysphagia were more prevalent among patients with OSA.</p><p><strong>Conclusion: </strong>Resistant hypertensive patients with OSA have a greater prevalence of changes in swallowing and worse Swal-QoL scores than those without OSA, although such changes were not shown in the EAT-10. In addition, Swal-Qol is related to swallowing safety impairments among these individuals.</p>","PeriodicalId":11508,"journal":{"name":"Dysphagia","volume":" ","pages":"851-860"},"PeriodicalIF":3.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142643976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sarcopenia, dysphagia, and frailty in community-dwelling older adults: An analysis of mediation and moderated mediation models.","authors":"Halil Ibrahim Celik, Mustafa Sari, Demet Ozturk, Aynur Ayse Karaduman","doi":"10.1007/s00455-024-10774-3","DOIUrl":"10.1007/s00455-024-10774-3","url":null,"abstract":"<p><p>Sarcopenia, dysphagia, and frailty are geriatric syndromes that commonly occur with age and are associated with various adverse health consequences. Nevertheless, the complex associations among them require further study to be clarified. The objectives of this study were to investigate (1) the potential role of dysphagia as a mediator in the association between sarcopenia and frailty and (2) the potential role of taste and smell dysfunction as a moderator of this mediator effect in community-dwelling older adults. A total of 352 older adults (mean age = 70.48 ± 5.31 years; 57.67% female) enrolled in this cross-sectional study. The SARC-F, Eating Assessment Tool-10 (EAT-10), and Edmonton Frailty Scale (EFS) were used to assess sarcopenia, dysphagia, and frailty, respectively. The Taste and Smell Dysfunction Questionnaire (TSDQ) was employed to assess taste and smell dysfunction. Frailty was present in 21.86%, sarcopenia risk in 39.77%, and dysphagia in 26.99% of the participants. The mediation analysis showed that the SARC-F had a significant effect on the EAT-10 (B = 1.001; p < 0.001), which in turn had a significant effect on the EFS (B = 0.129; p < 0.001). The direct (B = 0.659; p < 0.001), indirect (B = 0.129), and total (B = 0.778; p < 0.001) effects of SARC-F on EFS were significant. Of the association between sarcopenia and frailty, 16.6% was explained by dysphagia. The moderated mediation analysis showed that the TSDQ (B = 0.127; p < 0.001) moderated the association between SARC-F and EAT-10 and that the EAT-10 mediated the association between SARC-F and EFS only in older adults who scored moderate and high on the TSDQ (B = 0.049 and B = 0.114, respectively). The EAT-10 partially mediates the association between the SARC-F and the EFS, implying that sarcopenia affects frailty indirectly via dysphagia. Furthermore, taste and smell dysfunction moderates this mediator effect, with sarcopenia functioning as a mediator in older adults who scored moderate and high on the TSDQ. Therefore, it is plausible to anticipate that if someone has taste and smell dysfunction in addition to sarcopenia, they are more likely to have dysphagia and, ultimately, frailty. These findings emphasize the importance of addressing sarcopenia, taste and smell dysfunction, and dysphagia concurrently in frailty management in older adults.</p>","PeriodicalId":11508,"journal":{"name":"Dysphagia","volume":" ","pages":"767-774"},"PeriodicalIF":3.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cranial Nerve Deficits Predict Pharyngeal Phase Swallowing Impairment in Patients with Neurogenic Dysphagia: A Cross-Sectional Study.","authors":"Sara Nordio, Lorenza Maistrello, Isabella Koch, Daniela D'Imperio, Irene Battel","doi":"10.1007/s00455-024-10787-y","DOIUrl":"10.1007/s00455-024-10787-y","url":null,"abstract":"<p><p>The examination of the cranial nerves (CN) provides an accurate analysis of facial-oral integrity, motility and sensitivity that is fundamental to understanding swallowing efficiency. The aim of this cross-sectional study is to verify whether the assessment of CN can provide information on the amount and location of pharyngeal residue and risk of aspiration in patients with neurogenic dysphagia. A total of 96 dysphagic patients have been enrolled. Pharyngeal residue was assessed by the Italian version of the Yale Pharyngeal Residue Severity Rating Scale (IT-YPRSRS) and presence of penetration/aspiration using the Penetration-Aspiration Scale (PAS) during Fiberoptic Endoscopic Evaluation of Swallowing (FEES), while CNs were evaluated using the I&I test. Logistic regression models were used to investigate causal associations; for each of the CN found to be significant, the optimal cut-off to best discriminate healthy patients from those with pathology was calculated. All statistical analyses were performed using R software with the significance level set at P < 0.05. Significant correlations were found between total scores on the I&I test and the PAS and IT-YPRSRS results. Impairment of CN VII was a sensitive and specific predictor of vallecular residue. Deficits of V CN and X CN were predictors of pyriform sinus residue. PAS scores were just below the statistical significance. Assessing CN can provide specific pathophysiological information about pharyngeal residue and risk of penetration/aspiration. These findings could help clinicians understand swallowing issues and early plan targeted interventions.</p>","PeriodicalId":11508,"journal":{"name":"Dysphagia","volume":" ","pages":"886-901"},"PeriodicalIF":3.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}